Publications:

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Overview on Therapeutic Options in Uncommon EGFR Mutant Non-Small Cell Lung Cancer (NSCLC): New Lights for an Unmet Medical Need.

International Journal Of Molecular Sciences

Pretelli, Giulia G; Spagnolo, Calogera Claudia CC; Ciappina, Giuliana G; Santarpia, Mariacarmela M; Pasello, Giulia G

Publication Date: 2023-05-17

Variant appearance in text: EGFR: V689L

PubMed Link: 37240224

Variant Present in the following documents:

• Main text
• ijms-24-08878.pdf

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Comprehensive analyses of genomic features and mutational signatures in adenosquamous carcinoma of the lung.

Frontiers In Oncology

Wang, Hongbiao H; Liu, Jun J; Zhu, Sujuan S; Miao, Kun K; Li, Zhifeng Z; Qi, Xiaofang X; Huang, Lujia L; Guo, Lijie L; Wang, Yan Y; Cai, Yuyin Y; Lin, Yingcheng Y

Publication Date: 2022

Variant appearance in text: EGFR: V689L

PubMed Link: 36185247

Variant Present in the following documents:

• Main text
• fonc-12-945843.pdf

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AXL and Error-Prone DNA Replication Confer Drug Resistance and Offer Strategies to Treat EGFR-Mutant Lung Cancer.

Cancer Discovery

Noronha, Ashish A; Belugali Nataraj, Nishanth N; Lee, Joo Sang JS; Zhitomirsky, Benny B; Oren, Yaara Y; Oster, Sara S; Lindzen, Moshit M; Mukherjee, Saptaparna S; Will, Rainer R; Ghosh, Soma S; Simoni-Nieves, Arturo A; Verma, Aakanksha A; Chatterjee, Rishita R; Borgoni, Simone S; Robinson, Welles W; Sinha, Sanju S; Brandis, Alexander A; Kerr, D Lucas DL; Wu, Wei W; Sekar, Arunachalam A; Giri, Suvendu S; Chung, Youngmin Y; Drago-Garcia, Diana D; Danysh, Brian P BP; Lauriola, Mattia M; Fiorentino, Michelangelo M; Ardizzoni, Andrea A; Oren, Moshe M; Blakely, Collin M CM; Ezike, Jideofor J; Wiemann, Stefan S; Parida, Laxmi L; Bivona, Trever G TG; Aqeilan, Rami I RI; Brugge, Joan S JS; Regev, Aviv A; Getz, Gad G; Ruppin, Eytan E; Yarden, Yosef Y

Publication Date: 2022-11-02

Variant appearance in text: EGFR: V689L

PubMed Link: 35895872

Variant Present in the following documents:

• Main text
• 2666.pdf

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Investigation of PALB2 Mutation and Correlation With Immunotherapy Biomarker in Chinese Non-Small Cell Lung Cancer Patients.

Frontiers In Oncology

Zhang, Jiexia J; Tang, Shuangfeng S; Zhang, Chunning C; Li, Mingyao M; Zheng, Yating Y; Hu, Xue X; Huang, Mengli M; Cheng, Xiangyang X

Publication Date: 2021

Variant appearance in text: EGFR: 2065G>T; V689L

PubMed Link: 35087742

Variant Present in the following documents:

• Table_2.xlsx, sheet 1

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RBM10 Deficiency Is Associated With Increased Immune Activity in Lung Adenocarcinoma.

Frontiers In Oncology

Liu, Bing B; Wang, Yaqi Y; Wang, Han H; Li, Zhongwu Z; Yang, Lujing L; Yan, Shi S; Yang, Xin X; Ma, Yuanyuan Y; Gao, Xuan X; Guan, Yanfang Y; Yi, Xin X; Xia, Xuefeng X; Li, Jingjing J; Wu, Nan N

Publication Date: 2021

Variant appearance in text: EGFR: V689L

PubMed Link: 34367963

Variant Present in the following documents:

• Table_3.xlsx, sheet 1

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Clinical Value of EGFR Copy Number Gain Determined by Amplicon-Based Targeted Next Generation Sequencing in Patients with EGFR-Mutated NSCLC.

Targeted Oncology

Wei, Jiacong J; Meng, Pei P; Terpstra, Miente Martijn MM; van Rijk, Anke A; Tamminga, Menno M; Scherpen, Frank F; Ter Elst, Arja A; Alimohamed, Mohamed Z MZ; Johansson, Lennart F LF; Stigt, Jos J; Gijtenbeek, Rolof P G RPG; van Putten, John J; Hiltermann, T Jeroen N TJN; Groen, Harry J M HJM; Kok, Klaas K; van der Wekken, Anthonie J AJ; van den Berg, Anke A

Publication Date: 2021-03

Variant appearance in text: EGFR: V689L

PubMed Link: 33606136

Variant Present in the following documents:

• 11523_2021_798_MOESM1_ESM.pdf

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2065G>T; V689L

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

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The effectiveness of afatinib in patients with lung adenocarcinoma harboring complex epidermal growth factor receptor mutation.

Therapeutic Advances In Medical Oncology

Wu, Shang-Gin SG; Yu, Chong-Jen CJ; Yang, James Chih-Hsin JC; Shih, Jin-Yuan JY

Publication Date: 2020

Variant appearance in text: EGFR: V689L

PubMed Link: 32843903

Variant Present in the following documents:

• Main text
• 10.1177_1758835920946156.pdf

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Afatinib in the first-line treatment of patients with non-small cell lung cancer: clinical evidence and experience.

Therapeutic Advances In Respiratory Disease

Ricciuti, Biagio B; Baglivo, Sara S; De Giglio, Andrea A; Chiari, Rita R

Publication Date: 2018

Variant appearance in text: EGFR: V689L

PubMed Link: 30355049

Variant Present in the following documents:

• Main text
• 10.1177_1753466618808659.pdf

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Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma.

Cancer Biology & Therapy

Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS

Publication Date: 2016

Variant appearance in text: EGFR: V689L

PubMed Link: 26785607

Variant Present in the following documents:

• Main text
• kcbt-17-03-1139235.pdf

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Genetic heterogeneity of actionable genes between primary and metastatic tumor in lung adenocarcinoma.

Bmc Cancer

Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Kim, Arum A; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS

Publication Date: 2016-01-18

Variant appearance in text: EGFR: 2065G>T

PubMed Link: 26782967

Variant Present in the following documents:

• 12885_2016_2049_MOESM1_ESM.xlsx, sheet 1

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EGFR Exon 18 Mutations in East Asian Patients with Lung Adenocarcinomas: A Comprehensive Investigation of Prevalence, Clinicopathologic Characteristics and Prognosis.

Scientific Reports

Cheng, Chao C; Wang, Rui R; Li, Yuan Y; Pan, Yunjian Y; Zhang, Yang Y; Li, Hang H; Zheng, Difan D; Zheng, Shanbo S; Shen, Xuxia X; Sun, Yihua Y; Chen, Haiquan H

Publication Date: 2015-09-10

Variant appearance in text: EGFR: V689L

PubMed Link: 26354324

Variant Present in the following documents:

• Main text
• srep13959.pdf

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Pooled analysis of clinical outcome for EGFR TKI-treated patients with EGFR mutation-positive NSCLC.

Journal Of Cellular And Molecular Medicine

Paz-Ares, Luis L; Soulières, Denis D; Moecks, Joachim J; Bara, Ilze I; Mok, Tony T; Klughammer, Barbara B

Publication Date: 2014-08

Variant appearance in text: EGFR: V689L

PubMed Link: 25100284

Variant Present in the following documents:

• Main text
• jcmm0018-1519.pdf

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Frequency of driver mutations in lung adenocarcinoma from female never-smokers varies with histologic subtypes and age at diagnosis.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Zhang, Yang Y; Sun, Yihua Y; Pan, Yunjian Y; Li, Chenguang C; Shen, Lei L; Li, Yuan Y; Luo, Xiaoyang X; Ye, Ting T; Wang, Rui R; Hu, Haichuan H; Li, Hang H; Wang, Lei L; Pao, William W; Chen, Haiquan H

Publication Date: 2012-04-01

Variant appearance in text: EGFR: V689L

PubMed Link: 22317764

Variant Present in the following documents:

• Main text

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Genomic aberrations in lung adenocarcinoma in never smokers.

Plos One

Job, Bastien B; Bernheim, Alain A; Beau-Faller, Michèle M; Camilleri-Broët, Sophie S; Girard, Philippe P; Hofman, Paul P; Mazières, Julien J; Toujani, Saloua S; Lacroix, Ludovic L; Laffaire, Julien J; Dessen, Philippe P; Fouret, Pierre P; ,

Publication Date: 2010-12-06

Variant appearance in text: EGFR: Val689Leu

PubMed Link: 21151896

Variant Present in the following documents:

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Clinical outcomes in non-small-cell lung cancer patients with EGFR mutations: pooled analysis.

Journal Of Cellular And Molecular Medicine

Paz-Ares, Luis L; Soulières, Denis D; Melezínek, Ivan I; Moecks, Joachim J; Keil, Lorenz L; Mok, Tony T; Rosell, Rafael R; Klughammer, Barbara B

Publication Date: 2010-01

Variant appearance in text: EGFR: V689L

PubMed Link: 20015198

Variant Present in the following documents:

• Main text
• jcmm0014-0051.pdf

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