EGFR c.2071C>T ;(p.P691S)

Variant ID: 7-55241623-C-T

NM_005228.3(EGFR):c.2071C>T;(p.P691S)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene
Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S
Publication Date: 2022-04

Variant appearance in text: EGFR: P691S
PubMed Link: 35304574
Variant Present in the following documents:
  • 41388_2022_Article_2263.pdf
View BVdb publication page



Circulating tumour DNA in metastatic breast cancer to guide clinical trial enrolment and precision oncology: A cohort study.

Plos Medicine
Zivanovic Bujak, Andjelija A; Weng, Chen-Fang CF; Silva, Maria João MJ; Yeung, Miriam M; Lo, Louisa L; Ftouni, Sarah S; Litchfield, Cassandra C; Ko, Yi-An YA; Kuykhoven, Keilly K; Van Geelen, Courtney C; Chandrashekar, Sushma S; Dawson, Mark A MA; Loi, Sherene S; Wong, Stephen Q SQ; Dawson, Sarah-Jane SJ
Publication Date: 2020-10

Variant appearance in text: EGFR: P691S
PubMed Link: 33001984
Variant Present in the following documents:
  • pmed.1003363.s013.xlsx, sheet 1
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: P691S
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Epidermal growth factor receptor somatic mutation analysis in 354 Chinese patients with non-small cell lung cancer.

Oncology Letters
Quan, Xueping X; Gao, Hongjun H; Wang, Zhikuan Z; Li, Jie J; Zhao, Wentao W; Liang, Wei W; Yu, Qiang Q; Guo, Dongliang D; Hao, Zhanping Z; Liu, Jingxin J
Publication Date: 2018-02

Variant appearance in text: EGFR: P691S
PubMed Link: 29434916
Variant Present in the following documents:
  • Main text
View BVdb publication page



Frequency and clinical relevance of EGFR mutations and EML4-ALK translocations in octogenarians with non-small cell lung cancer.

Oncotargets And Therapy
Tufman, Amanda A; Kahnert, Kathrin K; Duell, Thomas T; Kauffmann-Guerrero, Diego D; Milger, Katrin K; Schneider, Christian C; Stump, Julia J; Syunyaeva, Zulfiya Z; Huber, Rudolf Maria RM; Reu, Simone S
Publication Date: 2017

Variant appearance in text: EGFR: P691S
PubMed Link: 29123416
Variant Present in the following documents:
  • Main text
  • ott-10-5179.pdf
View BVdb publication page



'Classical' but not 'other' mutations of EGFR kinase domain are associated with clinical outcome in gefitinib-treated patients with non-small cell lung cancer.

British Journal Of Cancer
Pallis, A G AG; Voutsina, A A; Kalikaki, Ar A; Souglakos, J J; Briasoulis, E E; Murray, S S; Koutsopoulos, A A; Tripaki, M M; Stathopoulos, E E; Mavroudis, D D; Georgoulias, V V
Publication Date: 2007-12-03

Variant appearance in text: EGFR: P691S
PubMed Link: 18000506
Variant Present in the following documents:
  • Main text
  • 6604068a.pdf
View BVdb publication page