Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.
Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Frequency and clinical relevance of EGFR mutations and EML4-ALK translocations in octogenarians with non-small cell lung cancer.
Oncotargets And Therapy
Tufman, Amanda A; Kahnert, Kathrin K; Duell, Thomas T; Kauffmann-Guerrero, Diego D; Milger, Katrin K; Schneider, Christian C; Stump, Julia J; Syunyaeva, Zulfiya Z; Huber, Rudolf Maria RM; Reu, Simone S
'Classical' but not 'other' mutations of EGFR kinase domain are associated with clinical outcome in gefitinib-treated patients with non-small cell lung cancer.
British Journal Of Cancer
Pallis, A G AG; Voutsina, A A; Kalikaki, Ar A; Souglakos, J J; Briasoulis, E E; Murray, S S; Koutsopoulos, A A; Tripaki, M M; Stathopoulos, E E; Mavroudis, D D; Georgoulias, V V