EGFR c.2098A>G ;(p.N700D)

Variant ID: 7-55241650-A-G

NM_005228.3(EGFR):c.2098A>G;(p.N700D)

This variant was identified in 12 publications

View GRCh38 version.




Publications:


[Progress in Detection of EGFR Exon 20 Insertion Mutation and Targeted Therapies 
in Non-small Cell Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Wang, Yulu Y; Chu, Tianqing T
Publication Date: 2023-02-20

Variant appearance in text: EGFR: N700D
PubMed Link: 36872052
Variant Present in the following documents:
  • zgfazz-26-135.pdf
View BVdb publication page



Rationale and design of a phase II trial of dacomitinib in advanced non-small cell lung cancer patients with uncommon epidermal growth factor receptor mutations: a prospective and single arm study (DANCE study).

Bmc Cancer
Zhang, Bo B; Shi, Chunlei C; Gao, Zhiqiang Z; Zhong, Hua H; Xiong, Liwen L; Gu, Aiqin A; Wang, Weimin W; Chu, Tianqing T; Zhang, Wei W; Wang, Huimin H; Zhang, Xueyan X; Zhong, Runbo R; Han, Baohui B
Publication Date: 2022-03-19

Variant appearance in text: EGFR: N700D
PubMed Link: 35305596
Variant Present in the following documents:
  • Main text
  • 12885_2022_Article_9409.pdf
View BVdb publication page



Durable response to afatinib in an advanced lung adenocarcinoma patient with an EGFR L858R/G729A compound mutation: a case report.

Annals Of Translational Medicine
Wu, Lige L; Fang, Cheng C; Zhao, Weiqing W; Li, Dong D; Tang, Shuxian S; Li, Xi X; Ji, Mei M
Publication Date: 2022-01

Variant appearance in text: EGFR: N700D
PubMed Link: 35282062
Variant Present in the following documents:
  • Main text
  • atm-10-02-116.pdf
View BVdb publication page



EGFR first- and second-generation TKIs-there is still place for them in EGFR-mutant NSCLC patients.

Translational Cancer Research
Karachaliou, Niki N; Fernandez-Bruno, Manuel M; Bracht, Jillian Wilhelmina Paulina JWP; Rosell, Rafael R
Publication Date: 2019-01

Variant appearance in text: EGFR: N700D
PubMed Link: 35117062
Variant Present in the following documents:
  • tcr-08-S1-S23.pdf
View BVdb publication page



[A Review of EGFR-TKIs Therapy of Non-small Cell Lung Cancer
with Uncommon EGFR Mutations].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Du, Wenxing W; Wo, Yang Y; Lu, Tong T; Wang, Yuanyong Y; Jiao, Wenjie W
Publication Date: 2019-09-20

Variant appearance in text: EGFR: N700D
PubMed Link: 31526464
Variant Present in the following documents:
  • Main text
  • zgfazz-22-9-590.pdf
View BVdb publication page



Multigene Mutation Profiling and Clinical Characteristics of Small-Cell Lung Cancer in Never-Smokers vs. Heavy Smokers (Geno1.3-CLICaP).

Frontiers In Oncology
Cardona, Andrés F AF; Rojas, Leonardo L; Zatarain-Barrón, Zyanya Lucia ZL; Ruiz-Patiño, Alejandro A; Ricaurte, Luisa L; Corrales, Luis L; Martín, Claudio C; Freitas, Helano H; Cordeiro de Lima, Vladmir Cláudio VC; Rodriguez, July J; Avila, Jenny J; Bravo, Melissa M; Archila, Pilar P; Carranza, Hernán H; Vargas, Carlos C; Otero, Jorge J; Barrón, Feliciano F; Karachaliou, Niki N; Rosell, Rafael R; Arrieta, Oscar O
Publication Date: 2019

Variant appearance in text: EGFR: N700D
PubMed Link: 31058075
Variant Present in the following documents:
  • Main text
  • fonc-09-00254.pdf
View BVdb publication page



Heterogeneous Responses to Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors (TKIs) in Patients with Uncommon EGFR Mutations: New Insights and Future Perspectives in this Complex Clinical Scenario.

International Journal Of Molecular Sciences
Russo, Alessandro A; Franchina, Tindara T; Ricciardi, Giuseppina G; Battaglia, Alessandra A; Picciotto, Maria M; Adamo, Vincenzo V
Publication Date: 2019-03-21

Variant appearance in text: EGFR: N700D
PubMed Link: 30901844
Variant Present in the following documents:
  • Main text
  • ijms-20-01431.pdf
View BVdb publication page



Frequency, impact and a preclinical study of novel ERBB gene family mutations in HER2-positive breast cancer.

Therapeutic Advances In Medical Oncology
Elster, Naomi N; Toomey, Sinead S; Fan, Yue Y; Cremona, Mattia M; Morgan, Clare C; Weiner Gorzel, Karolina K; Bhreathnach, Una U; Milewska, Malgorzata M; Murphy, Madeline M; Madden, Stephen S; Naidoo, Jarushka J; Fay, Joanna J; Kay, Elaine E; Carr, Aoife A; Kennedy, Sean S; Furney, Simon S; Mezynski, Janusz J; Breathhnach, Oscar O; Morris, Patrick P; Grogan, Liam L; Hill, Arnold A; Kennedy, Susan S; Crown, John J; Gallagher, William W; Hennessy, Bryan B; Eustace, Alex A
Publication Date: 2018

Variant appearance in text: EGFR: N700D
PubMed Link: 30023006
Variant Present in the following documents:
  • Supplementary_material.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: N700D
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 2
  • pone.0196434.s001.xlsx, sheet 1
View BVdb publication page



BRCA2, EGFR, and NTRK mutations in mismatch repair-deficient colorectal cancers with MSH2 or MLH1 mutations.

Oncotarget
Deihimi, Safoora S; Lev, Avital A; Slifker, Michael M; Shagisultanova, Elena E; Xu, Qifang Q; Jung, Kyungsuk K; Vijayvergia, Namrata N; Ross, Eric A EA; Xiu, Joanne J; Swensen, Jeffrey J; Gatalica, Zoran Z; Andrake, Mark M; Dunbrack, Roland L RL; El-Deiry, Wafik S WS
Publication Date: 2017-06-20

Variant appearance in text: EGFR: N700D
PubMed Link: 28591715
Variant Present in the following documents:
  • Main text
  • oncotarget-08-39945.pdf
View BVdb publication page



Epidermal growth factor receptor in non-small cell lung cancer.

Translational Lung Cancer Research
Prabhakar, Charles N CN
Publication Date: 2015-04

Variant appearance in text: EGFR: N700D
PubMed Link: 25870793
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mechanisms of drug resistance in kinases.

Expert Opinion On Investigational Drugs
Barouch-Bentov, Rina R; Sauer, Karsten K
Publication Date: 2011-02

Variant appearance in text: EGFR: N700D
PubMed Link: 21235428
Variant Present in the following documents:
  • Main text
View BVdb publication page