Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.
Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Circulating-free DNA Mutation Associated with Response of Targeted Therapy in Human Epidermal Growth Factor Receptor 2-positive Metastatic Breast Cancer.
Chinese Medical Journal
Ye, Qing Q; Qi, Fan F; Bian, Li L; Zhang, Shao-Hua SH; Wang, Tao T; Jiang, Ze-Fei ZF
EGFR exon-level biomarkers of the response to bevacizumab/erlotinib in non-small cell lung cancer.
Plos One
Baty, Florent F; Rothschild, Sacha S; Früh, Martin M; Betticher, Daniel D; Dröge, Cornelia C; Cathomas, Richard R; Rauch, Daniel D; Gautschi, Oliver O; Bubendorf, Lukas L; Crowe, Susanne S; Zappa, Francesco F; Pless, Miklos M; Brutsche, Martin M; ,
A patient-derived somatic mutation in the epidermal growth factor receptor ligand-binding domain confers increased sensitivity to cetuximab in head and neck cancer.
European Journal Of Cancer (Oxford, England : 1990)
Bahassi, El Mustapha el M; Li, Ya-Qin YQ; Wise-Draper, Trisha M TM; Deng, Li L; Wang, Jiang J; Darnell, Colleen N CN; Wilson, Keith M KM; Wells, Susanne I SI; Stambrook, Peter J PJ; Rixe, Olivier O