Publications:

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Overview on Therapeutic Options in Uncommon EGFR Mutant Non-Small Cell Lung Cancer (NSCLC): New Lights for an Unmet Medical Need.

International Journal Of Molecular Sciences

Pretelli, Giulia G; Spagnolo, Calogera Claudia CC; Ciappina, Giuliana G; Santarpia, Mariacarmela M; Pasello, Giulia G

Publication Date: 2023-05-17

Variant appearance in text: EGFR: I706T

PubMed Link: 37240224

Variant Present in the following documents:

• Main text
• ijms-24-08878.pdf

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: rs397517084

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 4

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Inconsistent clinical outcomes following afatinib treatment in NSCLC patients harboring uncommon epidermal growth factor receptor mutation.

Frontiers In Oncology

Dong, Wei W; Wang, Congjie C; Wang, Chunsheng C; Zhao, Kewei K; Ma, Zhao Z; Hu, Shanliang S

Publication Date: 2022

Variant appearance in text: EGFR: I706T

PubMed Link: 36425553

Variant Present in the following documents:

• DataSheet_1.pdf

View BVdb publication page

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Development and Validation of a Concise Prediction Scoring System for Asian Lung Cancer Patients with EGFR Mutation Before Treatment.

Technology In Cancer Research & Treatment

An, Wenting W; Fan, Wei W; Zhong, Feiyang F; Wang, Binchen B; Wang, Shan S; Gan, Tian T; Tian, Sufang S; Liao, Meiyan M

Publication Date: 2022

Variant appearance in text: EGFR: I706T

PubMed Link: 35234540

Variant Present in the following documents:

• Main text
• 10.1177_15330338221078732.pdf

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Real-World Approach for Molecular Analysis of Acquired EGFR Tyrosine Kinase Inhibitor Resistance Mechanisms in NSCLC.

Jto Clinical And Research Reports

Hondelink, Liesbeth M LM; Jebbink, Merel M; von der Thüsen, Jan H JH; Cohen, Danielle D; Dubbink, Hendrikus J HJ; Paats, Marthe S MS; Dingemans, Anne-Marie C AC; de Langen, Adrianus J AJ; Boelens, Mirjam C MC; Smit, Egbert F EF; Postmus, Pieter E PE; van Wezel, Tom T; Monkhorst, Kim K

Publication Date: 2021-12

Variant appearance in text: EGFR: I706T

PubMed Link: 34849493

Variant Present in the following documents:

• Main text
• main.pdf

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Oncogenic Fusions May Be Frequently Present at Resistance of EGFR Tyrosine Kinase Inhibitors in Patients With NSCLC: A Brief Report.

Jto Clinical And Research Reports

Enrico, Diego D; Lacroix, Ludovic L; Chen, Jeanne J; Rouleau, Etienne E; Scoazec, Jean-Yves JY; Loriot, Yohann Y; Tselikas, Lambros L; Jovelet, Cécile C; Planchard, David D; Gazzah, Anas A; Mezquita, Laura L; Ngo-Camus, Maud M; Michiels, Stefan S; Massard, Christophe C; Recondo, Gonzalo G; Facchinetti, Francesco F; Remon, Jordi J; Soria, Jean-Charles JC; André, Fabrice F; Vassal, Gilles G; Friboulet, Luc L; Besse, Benjamin B

Publication Date: 2020-06

Variant appearance in text: EGFR: I706T

PubMed Link: 34589930

Variant Present in the following documents:

• Main text

View BVdb publication page

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Mutation Spectrum of EGFR From 21,324 Chinese Patients With Non-Small Cell Lung Cancer (NSCLC) Successfully Tested by Multiple Methods in a CAP-Accredited Laboratory.

Pathology Oncology Research : Por

Mao, Linlin L; Zhao, Weiwei W; Li, Xiaoxia X; Zhang, Shangfei S; Zhou, Changhong C; Zhou, Danyan D; Ou, Xiaohua X; Xu, Yanyan Y; Tang, Yuanxiao Y; Ou, Xiaoyong X; Hu, Changming C; Ding, Xiangdong X; Luo, Pifu P; Yu, Shihui S

Publication Date: 2021

Variant appearance in text: EGFR: I706T

PubMed Link: 34257561

Variant Present in the following documents:

• Main text
• pore-27-602726.pdf

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Molecular characterization of advanced non-small cell lung cancer patients by cfDNA analysis: experience from routine laboratory practice.

Journal Of Thoracic Disease

González de Aledo-Castillo, José Manuel JM; Arcocha, Ainara A; Victoria, Iván I; Martinez-Puchol, Ana Isabel AI; Sánchez, Cristina C; Jares, Pedro P; Rodríguez, Gabriel Felipe GF; Viñolas, Núria N; Reyes, Roxana R; Reguart, Noemí N; Puig-Butillé, Joan Antón JA

Publication Date: 2021-03

Variant appearance in text: EGFR: Ile706Thr

PubMed Link: 33841957

Variant Present in the following documents:

• Main text

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Clinical impact of rebiopsy among patients with epidermal growth factor receptor-mutant lung adenocarcinoma in a real-world clinical setting.

Thoracic Cancer

Nam, Yunha Y; Kim, Ho Cheol HC; Kim, Young-Chul YC; Jang, Seung Hun SH; Lee, Kye Young KY; Lee, Shin Yup SY; Lee, Sang Hoon SH; Lee, Sung Yong SY; Yoon, Seong Hoon SH; Ryu, Jeong-Seon JS; Jang, Tae Won TW; Chang, Yoon Soo YS; Kim, Seung Joon SJ; Park, Chan Kwon CK; Lee, Jeong Eun JE; Jung, Chi Young CY; Choi, Chang-Min CM

Publication Date: 2021-03

Variant appearance in text: EGFR: I706T

PubMed Link: 33529490

Variant Present in the following documents:

• Main text
• TCA-12-890.pdf

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Heterogeneous Responses to Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors (TKIs) in Patients with Uncommon EGFR Mutations: New Insights and Future Perspectives in this Complex Clinical Scenario.

International Journal Of Molecular Sciences

Russo, Alessandro A; Franchina, Tindara T; Ricciardi, Giuseppina G; Battaglia, Alessandra A; Picciotto, Maria M; Adamo, Vincenzo V

Publication Date: 2019-03-21

Variant appearance in text: EGFR: I706T

PubMed Link: 30901844

Variant Present in the following documents:

• Main text
• ijms-20-01431.pdf

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Better Progression-Free Survival in Elderly Patients with Stage IV Lung Adenocarcinoma Harboring Uncommon Epidermal Growth Factor Receptor Mutations Treated with the First-line Tyrosine Kinase Inhibitors.

Cancers

Tsai, Ming-Ju MJ; Hung, Jen-Yu JY; Lee, Mei-Hsuan MH; Kuo, Chia-Yu CY; Tsai, Yu-Chen YC; Tsai, Ying-Ming YM; Liu, Ta-Chih TC; Yang, Chih-Jen CJ; Huang, Ming-Shyan MS; Chong, Inn-Wen IW

Publication Date: 2018-11-13

Variant appearance in text: EGFR: I706T

PubMed Link: 30428509

Variant Present in the following documents:

• Main text
• cancers-10-00434.pdf

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: EGFR: I706T

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 3
• pone.0196434.s001.xlsx, sheet 2
• pone.0196434.s001.xlsx, sheet 1

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Clinical mutational profiling of 1006 lung cancers by next generation sequencing.

Oncotarget

Illei, Peter B PB; Belchis, Deborah D; Tseng, Li-Hui LH; Nguyen, Doreen D; De Marchi, Federico F; Haley, Lisa L; Riel, Stacy S; Beierl, Katie K; Zheng, Gang G; Brahmer, Julie R JR; Askin, Frederic B FB; Gocke, Christopher D CD; Eshleman, James R JR; Forde, Patrick M PM; Lin, Ming-Tseh MT

Publication Date: 2017-11-14

Variant appearance in text: EGFR: I706T

PubMed Link: 29228562

Variant Present in the following documents:

• oncotarget-08-96684.pdf

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Lung adenocarcinoma patients of young age have lower EGFR mutation rate and poorer efficacy of EGFR tyrosine kinase inhibitors.

Erj Open Research

Wu, Shang-Gin SG; Chang, Yih-Leong YL; Yu, Chong-Jen CJ; Yang, Pan-Chyr PC; Shih, Jin-Yuan JY

Publication Date: 2017-07

Variant appearance in text: EGFR: I706T

PubMed Link: 28717642

Variant Present in the following documents:

• Main text
• 00092-2016.pdf

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Circulating-free DNA Mutation Associated with Response of Targeted Therapy in Human Epidermal Growth Factor Receptor 2-positive Metastatic Breast Cancer.

Chinese Medical Journal

Ye, Qing Q; Qi, Fan F; Bian, Li L; Zhang, Shao-Hua SH; Wang, Tao T; Jiang, Ze-Fei ZF

Publication Date: 2017-03-05

Variant appearance in text: EGFR: I706T

PubMed Link: 28229982

Variant Present in the following documents:

• CMJ-130-522.pdf

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Not all epidermal growth factor receptor mutations in lung cancer are created equal: Perspectives for individualized treatment strategy.

Cancer Science

Kobayashi, Yoshihisa Y; Mitsudomi, Tetsuya T

Publication Date: 2016-09

Variant appearance in text: EGFR: I706T

PubMed Link: 27323238

Variant Present in the following documents:

• Main text
• CAS-107-1179.pdf

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Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma.

Cancer Biology & Therapy

Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS

Publication Date: 2016

Variant appearance in text: EGFR: I706T

PubMed Link: 26785607

Variant Present in the following documents:

• Main text
• kcbt-17-03-1139235.pdf

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Different prognostic impact of STK11 mutations in non-squamous non-small-cell lung cancer.

Oncotarget

Pécuchet, Nicolas N; Laurent-Puig, Pierre P; Mansuet-Lupo, Audrey A; Legras, Antoine A; Alifano, Marco M; Pallier, Karine K; Didelot, Audrey A; Gibault, Laure L; Danel, Claire C; Just, Pierre-Alexandre PA; Riquet, Marc M; Le Pimpec-Barthes, Françoise F; Damotte, Diane D; Fabre, Elisabeth E; Blons, Hélène H

Publication Date: 2017-04-04

Variant appearance in text: EGFR: I706T

PubMed Link: 26625312

Variant Present in the following documents:

• oncotarget-08-23831-s002.xls, sheet 1

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EGFR Exon 18 Mutations in East Asian Patients with Lung Adenocarcinomas: A Comprehensive Investigation of Prevalence, Clinicopathologic Characteristics and Prognosis.

Scientific Reports

Cheng, Chao C; Wang, Rui R; Li, Yuan Y; Pan, Yunjian Y; Zhang, Yang Y; Li, Hang H; Zheng, Difan D; Zheng, Shanbo S; Shen, Xuxia X; Sun, Yihua Y; Chen, Haiquan H

Publication Date: 2015-09-10

Variant appearance in text: EGFR: I706T

PubMed Link: 26354324

Variant Present in the following documents:

• Main text

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Elderly former smoker with HRAS mutant non-small-cell lung cancer.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer

Cathcart-Rake, Elizabeth E; Corless, Christopher C; Sauer, David D; Lopez-Chavez, Ariel A

Publication Date: 2014-10

Variant appearance in text: EGFR: I706T

PubMed Link: 25521407

Variant Present in the following documents:

• jto-9-e075.pdf

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Impact of EGFR mutation detection methods on the efficacy of erlotinib in patients with advanced EGFR-wild type lung adenocarcinoma.

Plos One

Tseng, Jeng-Sen JS; Wang, Chih-Liang CL; Huang, Ming-Shyan MS; Chen, Chung-Yu CY; Chang, Cheng-Yu CY; Yang, Tsung-Ying TY; Tsai, Chi-Ren CR; Chen, Kun-Chieh KC; Hsu, Kuo-Hsuan KH; Tsai, Meen-Hsin MH; Yu, Sung-Liang SL; Su, Kang-Yi KY; Wu, Chih-Wei CW; Yang, Cheng-Ta CT; Chen, Yuh-Min YM; Chang, Gee-Chen GC

Publication Date: 2014

Variant appearance in text: EGFR: I706T

PubMed Link: 25215536

Variant Present in the following documents:

• Main text
• pone.0107160.pdf

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Co-conserved features associated with cis regulation of ErbB tyrosine kinases.

Plos One

Mirza, Amar A; Mustafa, Morad M; Talevich, Eric E; Kannan, Natarajan N

Publication Date: 2010-12-13

Variant appearance in text: EGFR: I706T

PubMed Link: 21179209

Variant Present in the following documents:

• Main text
• pone.0014310.pdf

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