EGFR c.2124G>T ;(p.K708N)

Variant ID: 7-55241676-G-T

NM_005228.3(EGFR):c.2124G>T;(p.K708N)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene
Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S
Publication Date: 2022-04

Variant appearance in text: EGFR: K708N
PubMed Link: 35304574
Variant Present in the following documents:
  • 41388_2022_Article_2263.pdf
View BVdb publication page



Development and validation of a multigene variant profiling assay to guide targeted and immuno therapy selection in solid tumors.

Plos One
Akolkar, Dadasaheb D; Patil, Darshana D; Srivastava, Navin N; Patil, Revati R; Datta, Vineet V; Apurwa, Sachin S; Yashwante, Nitin N; Dhasarathan, Raja R; Gosavi, Rahul R; John, Jinumary J; Khan, Shabishta S; Jadhav, Ninad N; Mene, Priti P; Ahire, Dhanashri D; Pawar, Sushant S; Bodke, Harshal H; Sahoo, Subhraline S; Nile, Arun A; Saindane, Dinesh D; Darokar, Harshal H; Devhare, Pradip P; Srinivasan, Ajay A; Datar, Rajan R
Publication Date: 2021

Variant appearance in text: EGFR: K708N
PubMed Link: 33556149
Variant Present in the following documents:
  • pone.0246048.s008.xlsx, sheet 1
View BVdb publication page



Non-classic EGFR mutations in a cohort of Dutch EGFR-mutated NSCLC patients and outcomes following EGFR-TKI treatment.

British Journal Of Cancer
Kuiper, J L JL; Hashemi, S M S SM; Thunnissen, E E; Snijders, P J F PJ; Grünberg, K K; Bloemena, E E; Sie, D D; Postmus, P E PE; Heideman, D A M DA; Smit, E F EF
Publication Date: 2016-12-06

Variant appearance in text: EGFR: K708N
PubMed Link: 27875527
Variant Present in the following documents:
  • Main text
  • bjc2016372a.pdf
View BVdb publication page



Next-generation sequencing of lung cancer EGFR exons 18-21 allows effective molecular diagnosis of small routine samples (cytology and biopsy).

Plos One
de Biase, Dario D; Visani, Michela M; Malapelle, Umberto U; Simonato, Francesca F; Cesari, Valentina V; Bellevicine, Claudio C; Pession, Annalisa A; Troncone, Giancarlo G; Fassina, Ambrogio A; Tallini, Giovanni G
Publication Date: 2013

Variant appearance in text: EGFR: K708N
PubMed Link: 24376723
Variant Present in the following documents:
  • Main text
  • pone.0083607.pdf
View BVdb publication page



Common and rare EGFR and KRAS mutations in a Dutch non-small-cell lung cancer population and their clinical outcome.

Plos One
Kerner, Gerald S M A GS; Schuuring, Ed E; Sietsma, Johanna J; Hiltermann, Thijo J N TJ; Pieterman, Remge M RM; de Leede, Gerard P J GP; van Putten, John W G JW; Liesker, Jeroen J; Renkema, Tineke E J TE; van Hengel, Peter P; Platteel, Inge I; Timens, Wim W; Groen, Harry J M HJ; ,
Publication Date: 2013

Variant appearance in text: EGFR: K708N
PubMed Link: 23922984
Variant Present in the following documents:
  • Main text
  • pone.0070346.pdf
View BVdb publication page