Molecular Profiling in Non-Squamous Non-Small Cell Lung Carcinoma: Towards a Switch to Next-Generation Sequencing Reflex Testing.
Journal Of Personalized Medicine
Pujol, Nina N; Heeke, Simon S; Bontoux, Christophe C; Boutros, Jacques J; Ilié, Marius M; Hofman, Véronique V; Marquette, Charles-Hugo CH; Hofman, Paul P; Benzaquen, Jonathan J
Real-world global data on targeting epidermal growth factor receptor mutations in stage III non-small-cell lung cancer: the results of the KINDLE study.
Therapeutic Advances In Medical Oncology
Jazieh, Abdul Rahman AR; Onal, Huseyin Cem HC; Tan, Daniel Shao-Weng DS; Soo, Ross A RA; Prabhash, Kumar K; Kumar, Amit A; Huggenberger, Reto R; Cho, Byoung Chul BC
Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.
Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society
Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.
Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Comparison of Resistance Spectra after First and Second Line Osimertinib Treatment Detected by Liquid Biopsy.
Cancers
Jóri, Balázs B; Schatz, Stefanie S; Kaller, Len L; Kah, Bettina B; Roeper, Julia J; Ramdani, Hayat O HO; Diehl, Linda L; Hoffknecht, Petra P; Grohé, Christian C; Griesinger, Frank F; Tiemann, Markus M; Heukamp, Lukas C LC; Falk, Markus M
Mass Spectrometry as a Highly Sensitive Method for Specific Circulating Tumor DNA Analysis in NSCLC: A Comparison Study.
Cancers
Lamy, Pierre-Jean PJ; van der Leest, Paul P; Lozano, Nicolas N; Becht, Catherine C; Duboeuf, Frédérique F; Groen, Harry J M HJM; Hilgers, Werner W; Pourel, Nicolas N; Rifaela, Naomi N; Schuuring, Ed E; Alix-Panabières, Catherine C
Rapid EGFR mutation testing in lung cancer tissue samples using a fully automated system and single-use cartridge.
Practical Laboratory Medicine
Al-Turkmani, M Rabie MR; Suriawinata, Michael A MA; Deharvengt, Sophie J SJ; Green, Donald C DC; Black, Candice C CC; Shirai, Keisuke K; Dragnev, Konstantin H KH; Tsongalis, Gregory J GJ
Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.
Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Discrepancies between ALK protein disruption and occurrence of ALK gene rearrangement in Polish NSCLC patients.
Journal Of Thoracic Disease
Grenda, Anna A; Jarosz, Bożena B; Krawczyk, Paweł P; Kucharczyk, Tomasz T; Wojas-Krawczyk, Kamila K; Reszka, Katarzyna K; Krukowska, Kinga K; Nicoś, Marcin M; Pankowski, Juliusz J; Bryl, Maciej M; Ramlau, Rodryg R; Kuźnar-Kamińska, Barbara B; Grodzki, Tomasz T; Szczęsna, Aleksandra A; Siemiątkowska, Krystyna K; Szumiło, Justyna J; Batura-Gabryel, Halina H; Palonka, Michał M; Milanowski, Janusz J
Publication Date: 2018-08
Variant appearance in text: EGFR: 2126A>T; Glu709Val
Immunohistochemical assays incorporating SP142 and 22C3 monoclonal antibodies for detection of PD-L1 expression in NSCLC patients with known status of EGFR and ALK genes.
Oncotarget
Krawczyk, Paweł P; Jarosz, Bożena B; Kucharczyk, Tomasz T; Grenda, Anna A; Reszka, Katarzyna K; Pankowski, Juliusz J; Wojas-Krawczyk, Kamila K; Nicoś, Marcin M; Szumiło, Justyna J; Trojanowski, Tomasz T; Milanowski, Janusz J
Publication Date: 2017-09-08
Variant appearance in text: EGFR: 2126A>T; Glu709Val
Pan-urologic cancer genomic subtypes that transcend tissue of origin.
Nature Communications
Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ
Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.
Genome Research
Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U
Analysis of progression-free survival of first-line tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring leu858Arg or exon 19 deletions.
The emergence of T790M mutation in EGFR-mutant lung adenocarcinoma patients having a history of acquired resistance to EGFR-TKI: focus on rebiopsy timing and long-term existence of T790M.
Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology.
Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer
Lindeman, Neal I NI; Cagle, Philip T PT; Beasley, Mary Beth MB; Chitale, Dhananjay Arun DA; Dacic, Sanja S; Giaccone, Giuseppe G; Jenkins, Robert Brian RB; Kwiatkowski, David J DJ; Saldivar, Juan-Sebastian JS; Squire, Jeremy J; Thunnissen, Erik E; Ladanyi, Marc M
Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology.
Archives Of Pathology & Laboratory Medicine
Lindeman, Neal I NI; Cagle, Philip T PT; Beasley, Mary Beth MB; Chitale, Dhananjay Arun DA; Dacic, Sanja S; Giaccone, Giuseppe G; Jenkins, Robert Brian RB; Kwiatkowski, David J DJ; Saldivar, Juan-Sebastian JS; Squire, Jeremy J; Thunnissen, Erik E; Ladanyi, Marc M
Compound EGFR mutations and response to EGFR tyrosine kinase inhibitors.
Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer
Kobayashi, Susumu S; Canepa, Hannah M HM; Bailey, Alexandra S AS; Nakayama, Sohei S; Yamaguchi, Norihiro N; Goldstein, Michael A MA; Huberman, Mark S MS; Costa, Daniel B DB
Absence of common activating mutations of the epidermal growth factor receptor gene in thyroid cancers from American and Japanese patients.
International Journal Of Cancer
Ricarte-Filho, Julio C JC; Matsuse, Michiko M; Lau, Christopher C; Ryder, Mabel M; Nishihara, Eijun E; Ghossein, Ronald A RA; Ladanyi, Marc M; Yamashita, Shunichi S; Mitsutake, Norisato N; Fagin, James A JA
High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected non-small cell lung cancer.
British Journal Of Cancer
Kim, D-W DW; Min, H S HS; Lee, K-H KH; Kim, Y J YJ; Oh, D-Y DY; Jeon, Y K YK; Lee, S-H SH; Im, S-A SA; Chung, D H DH; Kim, Y T YT; Kim, T-Y TY; Bang, Y-J YJ; Sung, S W SW; Kim, J H JH; Heo, D S DS