EGFR c.2126A>T ;(p.E709V)

Variant ID: 7-55241678-A-T

NM_005228.3(EGFR):c.2126A>T;(p.E709V)

This variant was identified in 51 publications

View GRCh38 version.




Publications:


Pan-cancer clinical impact of latent drivers from double mutations.

Communications Biology
Yavuz, Bengi Ruken BR; Tsai, Chung-Jung CJ; Nussinov, Ruth R; Tuncbag, Nurcan N
Publication Date: 2023-02-20

Variant appearance in text: EGFR: E709V
PubMed Link: 36808143
Variant Present in the following documents:
  • 42003_2023_4519_MOESM3_ESM.xlsx, sheet 3
View BVdb publication page



Successful treatment of a patient with advanced lung adenocarcinoma (EGFR-T790M and C797S cis) with lazertinib: A case report and literature review.

Frontiers In Oncology
Fang, Yue Y; Zhang, Qiankun Q; Wang, Weimin W; Tong, Juanjuan J; Li, Xialin X
Publication Date: 2022

Variant appearance in text: EGFR: Glu709Val
PubMed Link: 36698414
Variant Present in the following documents:
  • Main text
  • fonc-12-1037964.pdf
View BVdb publication page



Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics
G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A
Publication Date: 2022

Variant appearance in text: EGFR: E709V
PubMed Link: 36561320
Variant Present in the following documents:
  • Table3.xlsx, sheet 1
  • Table2.xlsx, sheet 4
View BVdb publication page



An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology
Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y
Publication Date: 2022

Variant appearance in text: EGFR: 2126A>T; E709V
PubMed Link: 36505399
Variant Present in the following documents:
  • Table_2.xlsx, sheet 3
  • Table_2.xlsx, sheet 2
View BVdb publication page



Multiple mutations in the EGFR gene in lung cancer: a systematic review.

Translational Lung Cancer Research
Castañeda-González, Juan Pablo JP; Chaves, Juan José JJ; Parra-Medina, Rafael R
Publication Date: 2022-10

Variant appearance in text: EGFR: E709V
PubMed Link: 36386461
Variant Present in the following documents:
  • Main text
  • tlcr-11-10-2148.pdf
View BVdb publication page



Molecular Profiling in Non-Squamous Non-Small Cell Lung Carcinoma: Towards a Switch to Next-Generation Sequencing Reflex Testing.

Journal Of Personalized Medicine
Pujol, Nina N; Heeke, Simon S; Bontoux, Christophe C; Boutros, Jacques J; Ilié, Marius M; Hofman, Véronique V; Marquette, Charles-Hugo CH; Hofman, Paul P; Benzaquen, Jonathan J
Publication Date: 2022-10-09

Variant appearance in text: EGFR: E709V
PubMed Link: 36294823
Variant Present in the following documents:
  • Main text
  • jpm-12-01684.pdf
View BVdb publication page



Real-world global data on targeting epidermal growth factor receptor mutations in stage III non-small-cell lung cancer: the results of the KINDLE study.

Therapeutic Advances In Medical Oncology
Jazieh, Abdul Rahman AR; Onal, Huseyin Cem HC; Tan, Daniel Shao-Weng DS; Soo, Ross A RA; Prabhash, Kumar K; Kumar, Amit A; Huggenberger, Reto R; Cho, Byoung Chul BC
Publication Date: 2022

Variant appearance in text: EGFR: E709V
PubMed Link: 36119641
Variant Present in the following documents:
  • Main text
  • 10.1177_17588359221122720.pdf
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: EGFR: 2126A>T; E709V
PubMed Link: 35936718
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society
Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW
Publication Date: 2022-05-23

Variant appearance in text: EGFR: 2126A>T; Glu709Val
PubMed Link: 35606799
Variant Present in the following documents:
  • 41021_2022_248_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications
Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L
Publication Date: 2022-03-10

Variant appearance in text: EGFR: 2126A>T; E709V
PubMed Link: 35273153
Variant Present in the following documents:
  • 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Various Subtypes of EGFR Mutations in Patients With NSCLC Define Genetic, Immunologic Diversity and Possess Different Prognostic Biomarkers.

Frontiers In Immunology
Lei, Youming Y; Wang, Kun K; Liu, Yinqiang Y; Wang, Xuming X; Xiang, Xudong X; Ning, Xiangu X; Ding, Wanbao W; Duan, Jin J; Li, Dingbiao D; Zhao, Wei W; Li, Yi Y; Zhang, Fujun F; Luo, Xiaoyu X; Shi, Yunfei Y; Wang, Ying Y; Huang, Depei D; Bai, Yuezong Y; Zhang, Hushan H
Publication Date: 2022

Variant appearance in text: EGFR: E709V
PubMed Link: 35265073
Variant Present in the following documents:
  • Main text
  • fimmu-13-811601.pdf
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: EGFR: E709V
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine
Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z
Publication Date: 2021-10

Variant appearance in text: EGFR: Glu709Val
PubMed Link: 34599863
Variant Present in the following documents:
  • CAM4-10-7360-s002.xlsx, sheet 2
View BVdb publication page



Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine
Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z
Publication Date: 2021-10

Variant appearance in text: EGFR: Glu709Val
PubMed Link: 34599863
Variant Present in the following documents:
  • CAM4-10-7360-s002.xlsx, sheet 2
View BVdb publication page



The Potential Use of Dynamics Changes of ctDNA and cfDNA in the Perioperative Period to Predict the Recurrence Risk in Early NSCLC.

Frontiers In Oncology
Zhao, Xiaolong X; Dai, Fuqiang F; Mei, Longyong L; Huang, Depei D; Shen, Xudong X; Zhang, Hushan H; She, Xueke X; Ma, Zheng Z
Publication Date: 2021

Variant appearance in text: EGFR: E709V
PubMed Link: 34336662
Variant Present in the following documents:
  • Main text
  • fonc-11-671963.pdf
View BVdb publication page



Neoantigen vaccination induces clinical and immunologic responses in non-small cell lung cancer patients harboring EGFR mutations.

Journal For Immunotherapy Of Cancer
Li, Fenge F; Deng, Ligang L; Jackson, Kyle R KR; Talukder, Amjad H AH; Katailiha, Arjun S AS; Bradley, Sherille D SD; Zou, Qingwei Q; Chen, Caixia C; Huo, Chong C; Chiu, Yulun Y; Stair, Matthew M; Feng, Weihong W; Bagaev, Aleksander A; Kotlov, Nikita N; Svekolkin, Viktor V; Ataullakhanov, Ravshan R; Miheecheva, Natalia N; Frenkel, Felix F; Wang, Yaling Y; Zhang, Minying M; Hawke, David D; Han, Ling L; Zhou, Shuo S; Zhang, Yan Y; Wang, Zhenglu Z; Decker, William K WK; Sonnemann, Heather M HM; Roszik, Jason J; Forget, Marie-Andree MA; Davies, Michael A MA; Bernatchez, Chantale C; Yee, Cassian C; Bassett, Roland R; Hwu, Patrick P; Du, Xueming X; Lizee, Gregory G
Publication Date: 2021-07

Variant appearance in text: EGFR: E709V
PubMed Link: 34244308
Variant Present in the following documents:
  • jitc-2021-002531supp006.xlsx, sheet 1
  • jitc-2021-002531supp004.xlsx, sheet 1
View BVdb publication page



Comparison of Resistance Spectra after First and Second Line Osimertinib Treatment Detected by Liquid Biopsy.

Cancers
Jóri, Balázs B; Schatz, Stefanie S; Kaller, Len L; Kah, Bettina B; Roeper, Julia J; Ramdani, Hayat O HO; Diehl, Linda L; Hoffknecht, Petra P; Grohé, Christian C; Griesinger, Frank F; Tiemann, Markus M; Heukamp, Lukas C LC; Falk, Markus M
Publication Date: 2021-06-08

Variant appearance in text: EGFR: E709V
PubMed Link: 34201252
Variant Present in the following documents:
  • Main text
  • cancers-13-02861.pdf
View BVdb publication page



Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: EGFR: 2126A>T; E709V
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2126A>T; E709V
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Mass Spectrometry as a Highly Sensitive Method for Specific Circulating Tumor DNA Analysis in NSCLC: A Comparison Study.

Cancers
Lamy, Pierre-Jean PJ; van der Leest, Paul P; Lozano, Nicolas N; Becht, Catherine C; Duboeuf, Frédérique F; Groen, Harry J M HJM; Hilgers, Werner W; Pourel, Nicolas N; Rifaela, Naomi N; Schuuring, Ed E; Alix-Panabières, Catherine C
Publication Date: 2020-10-16

Variant appearance in text: EGFR: 2126A>T; E709V
PubMed Link: 33081150
Variant Present in the following documents:
  • cancers-12-03002-s001.pdf
View BVdb publication page



Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports
Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O
Publication Date: 2020-10-13

Variant appearance in text: rs397517085
PubMed Link: 33051506
Variant Present in the following documents:
  • 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



The effectiveness of afatinib in patients with lung adenocarcinoma harboring complex epidermal growth factor receptor mutation.

Therapeutic Advances In Medical Oncology
Wu, Shang-Gin SG; Yu, Chong-Jen CJ; Yang, James Chih-Hsin JC; Shih, Jin-Yuan JY
Publication Date: 2020

Variant appearance in text: EGFR: E709V
PubMed Link: 32843903
Variant Present in the following documents:
  • Main text
  • 10.1177_1758835920946156.pdf
View BVdb publication page



Rapid EGFR mutation testing in lung cancer tissue samples using a fully automated system and single-use cartridge.

Practical Laboratory Medicine
Al-Turkmani, M Rabie MR; Suriawinata, Michael A MA; Deharvengt, Sophie J SJ; Green, Donald C DC; Black, Candice C CC; Shirai, Keisuke K; Dragnev, Konstantin H KH; Tsongalis, Gregory J GJ
Publication Date: 2020-05

Variant appearance in text: EGFR: E709V
PubMed Link: 32181314
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: EGFR: E709V
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



Validation and Clinical Applications of a Comprehensive Next Generation Sequencing System for Molecular Characterization of Solid Cancer Tissues.

Frontiers In Molecular Biosciences
Dehghani, Mehdi M; Rosenblatt, Kevin P KP; Li, Lei L; Rakhade, Mrudula M; Amato, Robert J RJ
Publication Date: 2019

Variant appearance in text: EGFR: E709V
PubMed Link: 31681791
Variant Present in the following documents:
  • Data_Sheet_9.xlsx, sheet 1
View BVdb publication page



Variation in nomenclature of somatic variants for selection of oncological therapies: Can we reach a consensus soon?

Human Mutation
Keppens, Cleo C; Tack, Véronique V; Dufraing, Kelly K; Rouleau, Etienne E; Ligtenberg, Marjolijn J L MJL; Schuuring, Ed E; Dequeker, Elisabeth M C EMC
Publication Date: 2020-01

Variant appearance in text: EGFR: 2126A>T; Glu709Val
PubMed Link: 31553104
Variant Present in the following documents:
  • HUMU-41-7-s001.pdf
View BVdb publication page



Discrepancies between ALK protein disruption and occurrence of ALK gene rearrangement in Polish NSCLC patients.

Journal Of Thoracic Disease
Grenda, Anna A; Jarosz, Bożena B; Krawczyk, Paweł P; Kucharczyk, Tomasz T; Wojas-Krawczyk, Kamila K; Reszka, Katarzyna K; Krukowska, Kinga K; Nicoś, Marcin M; Pankowski, Juliusz J; Bryl, Maciej M; Ramlau, Rodryg R; Kuźnar-Kamińska, Barbara B; Grodzki, Tomasz T; Szczęsna, Aleksandra A; Siemiątkowska, Krystyna K; Szumiło, Justyna J; Batura-Gabryel, Halina H; Palonka, Michał M; Milanowski, Janusz J
Publication Date: 2018-08

Variant appearance in text: EGFR: 2126A>T; Glu709Val
PubMed Link: 30233874
Variant Present in the following documents:
  • Main text
View BVdb publication page



Oncogene mutational analysis in Chinese gastrointestinal stromal tumor patients.

Oncotargets And Therapy
Chen, Qiong Q; Li, Rong R; Zhang, Zhi-Gao ZG; Deng, Qiao-Ting QT; Li, Kun K; Wang, Hao H; Yang, Xue-Xi XX; Wu, Ying-Song YS
Publication Date: 2018

Variant appearance in text: EGFR: E709V
PubMed Link: 29719410
Variant Present in the following documents:
  • Main text
  • ott-11-2279.pdf
View BVdb publication page



Intercalated Treatment Following Rebiopsy Is Associated with a Shorter Progression-Free Survival of Osimertinib Treatment.

Cancer Research And Treatment
Tseng, Jeng-Sen JS; Yang, Tsung-Ying TY; Chen, Kun-Chieh KC; Hsu, Kuo-Hsuan KH; Huang, Yen-Hsiang YH; Su, Kang-Yi KY; Yu, Sung-Liang SL; Chang, Gee-Chen GC
Publication Date: 2018-10

Variant appearance in text: EGFR: E709V
PubMed Link: 29228521
Variant Present in the following documents:
  • crt-2017-460-suppl1.pdf
View BVdb publication page



Immunohistochemical assays incorporating SP142 and 22C3 monoclonal antibodies for detection of PD-L1 expression in NSCLC patients with known status of EGFR and ALK genes.

Oncotarget
Krawczyk, Paweł P; Jarosz, Bożena B; Kucharczyk, Tomasz T; Grenda, Anna A; Reszka, Katarzyna K; Pankowski, Juliusz J; Wojas-Krawczyk, Kamila K; Nicoś, Marcin M; Szumiło, Justyna J; Trojanowski, Tomasz T; Milanowski, Janusz J
Publication Date: 2017-09-08

Variant appearance in text: EGFR: 2126A>T; Glu709Val
PubMed Link: 28969070
Variant Present in the following documents:
  • Main text
  • oncotarget-08-64283.pdf
View BVdb publication page



Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications
Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ
Publication Date: 2017-08-04

Variant appearance in text: EGFR: 2126A>T; E709V
PubMed Link: 28775315
Variant Present in the following documents:
  • 41467_2017_289_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Prevalence of EGFR Mutations in Lung Cancer in Uruguayan Population.

Journal Of Cancer Epidemiology
Berois, Nora N; Touya, Diego D; Ubillos, Luis L; Bertoni, Bernardo B; Osinaga, Eduardo E; Varangot, Mario M
Publication Date: 2017

Variant appearance in text: EGFR: 2126A>T; E709V
PubMed Link: 28744312
Variant Present in the following documents:
  • Main text
  • JCE2017-6170290.pdf
View BVdb publication page



Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research
Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U
Publication Date: 2017-04

Variant appearance in text: EGFR: 2126A>T; E709V
PubMed Link: 28179366
Variant Present in the following documents:
  • supp_gr.213546.116_Supplemental_Table_S7.xlsx, sheet 1
View BVdb publication page



Analysis of progression-free survival of first-line tyrosine kinase inhibitors in patients with non-small cell lung cancer harboring leu858Arg or exon 19 deletions.

Oncotarget
Kuan, Feng-Che FC; Li, Shih-Hong SH; Wang, Chih-Liang CL; Lin, Meng-Hung MH; Tsai, Ying-Huang YH; Yang, Cheng-Ta CT
Publication Date: 2017-01-03

Variant appearance in text: EGFR: E709V
PubMed Link: 27935868
Variant Present in the following documents:
  • oncotarget-08-1343-s001.pdf
View BVdb publication page



Effectiveness of tyrosine kinase inhibitors on uncommon E709X epidermal growth factor receptor mutations in non-small-cell lung cancer.

Oncotargets And Therapy
Wu, Jenn-Yu JY; Shih, Jin-Yuan JY
Publication Date: 2016

Variant appearance in text: EGFR: E709V
PubMed Link: 27785061
Variant Present in the following documents:
  • Main text
  • ott-9-6137.pdf
View BVdb publication page



The emergence of T790M mutation in EGFR-mutant lung adenocarcinoma patients having a history of acquired resistance to EGFR-TKI: focus on rebiopsy timing and long-term existence of T790M.

Oncotarget
Tseng, Jeng-Sen JS; Su, Kang-Yi KY; Yang, Tsung-Ying TY; Chen, Kun-Chieh KC; Hsu, Kuo-Hsuan KH; Chen, Hsuan-Yu HY; Tsai, Chi-Ren CR; Yu, Sung-Liang SL; Chang, Gee-Chen GC
Publication Date: 2016-07-26

Variant appearance in text: EGFR: E709V
PubMed Link: 27384480
Variant Present in the following documents:
  • oncotarget-07-48059-s001.pdf
View BVdb publication page



Identification of five driver gene mutations in patients with treatment-naïve lung adenocarcinoma in Taiwan.

Plos One
Hsu, Kuo-Hsuan KH; Ho, Chao-Chi CC; Hsia, Te-Chun TC; Tseng, Jeng-Sen JS; Su, Kang-Yi KY; Wu, Ming-Fang MF; Chiu, Kuo-Liang KL; Yang, Tsung-Ying TY; Chen, Kun-Chieh KC; Ooi, Hean H; Wu, Tzu-Chin TC; Chen, Hung-Jen HJ; Chen, Hsuan-Yu HY; Chang, Chi-Sheng CS; Hsu, Chung-Ping CP; Hsia, Jiun-Yi JY; Chuang, Cheng-Yen CY; Lin, Chin-Hung CH; Chen, Jeremy J W JJ; Chen, Kuan-Yu KY; Liao, Wei-Yu WY; Shih, Jin-Yuan JY; Yu, Sung-Liang SL; Yu, Chong-Jen CJ; Yang, Pan-Chyr PC; Chang, Gee-Chen GC
Publication Date: 2015

Variant appearance in text: EGFR: E709V
PubMed Link: 25789627
Variant Present in the following documents:
  • Main text
  • pone.0120852.pdf
View BVdb publication page



Impact of EGFR mutation detection methods on the efficacy of erlotinib in patients with advanced EGFR-wild type lung adenocarcinoma.

Plos One
Tseng, Jeng-Sen JS; Wang, Chih-Liang CL; Huang, Ming-Shyan MS; Chen, Chung-Yu CY; Chang, Cheng-Yu CY; Yang, Tsung-Ying TY; Tsai, Chi-Ren CR; Chen, Kun-Chieh KC; Hsu, Kuo-Hsuan KH; Tsai, Meen-Hsin MH; Yu, Sung-Liang SL; Su, Kang-Yi KY; Wu, Chih-Wei CW; Yang, Cheng-Ta CT; Chen, Yuh-Min YM; Chang, Gee-Chen GC
Publication Date: 2014

Variant appearance in text: EGFR: E709V
PubMed Link: 25215536
Variant Present in the following documents:
  • pone.0107160.s001.pdf
  • pone.0107160.s004.pdf
View BVdb publication page



Oncogene mutational profile in nasopharyngeal carcinoma.

Oncotargets And Therapy
Zhang, Zi-Chen ZC; Fu, Sha S; Wang, Fang F; Wang, Hai-Yun HY; Zeng, Yi-Xin YX; Shao, Jian-Yong JY
Publication Date: 2014

Variant appearance in text: EGFR: E709V
PubMed Link: 24672248
Variant Present in the following documents:
  • Main text
  • ott-7-457.pdf
View BVdb publication page



Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer
Lindeman, Neal I NI; Cagle, Philip T PT; Beasley, Mary Beth MB; Chitale, Dhananjay Arun DA; Dacic, Sanja S; Giaccone, Giuseppe G; Jenkins, Robert Brian RB; Kwiatkowski, David J DJ; Saldivar, Juan-Sebastian JS; Squire, Jeremy J; Thunnissen, Erik E; Ladanyi, Marc M
Publication Date: 2013-07

Variant appearance in text: EGFR: 2126A>T; E709V
PubMed Link: 23552377
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology.

Archives Of Pathology & Laboratory Medicine
Lindeman, Neal I NI; Cagle, Philip T PT; Beasley, Mary Beth MB; Chitale, Dhananjay Arun DA; Dacic, Sanja S; Giaccone, Giuseppe G; Jenkins, Robert Brian RB; Kwiatkowski, David J DJ; Saldivar, Juan-Sebastian JS; Squire, Jeremy J; Thunnissen, Erik E; Ladanyi, Marc M
Publication Date: 2013-06

Variant appearance in text: EGFR: 2126A>T; E709V
PubMed Link: 23551194
Variant Present in the following documents:
  • Main text
View BVdb publication page



Compound EGFR mutations and response to EGFR tyrosine kinase inhibitors.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer
Kobayashi, Susumu S; Canepa, Hannah M HM; Bailey, Alexandra S AS; Nakayama, Sohei S; Yamaguchi, Norihiro N; Goldstein, Michael A MA; Huberman, Mark S MS; Costa, Daniel B DB
Publication Date: 2013-01

Variant appearance in text: EGFR: E709V
PubMed Link: 23242437
Variant Present in the following documents:
  • Main text
View BVdb publication page



Fresh surgical specimens yield breast stem/progenitor cells and reveal their oncogenic abnormalities.

Annals Of Surgical Oncology
Pommier, Suellen J SJ; Hernandez, Ariel A; Han, Esther E; Massimino, Kristen K; Muller, Patrick P; Diggs, Brian B; Chamberlain, Erin E; Murphy, Jennifer J; Hansen, Juliana J; Naik, Arpana A; Vetto, John J; Pommier, Rodney F RF
Publication Date: 2012-02

Variant appearance in text: EGFR: E709V
PubMed Link: 21748247
Variant Present in the following documents:
  • 10434_2011_1892_MOESM2_ESM.pdf
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Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research
Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C
Publication Date: 2011-09-01

Variant appearance in text: EGFR: E709V
PubMed Link: 21727090
Variant Present in the following documents:
  • supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1
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Absence of common activating mutations of the epidermal growth factor receptor gene in thyroid cancers from American and Japanese patients.

International Journal Of Cancer
Ricarte-Filho, Julio C JC; Matsuse, Michiko M; Lau, Christopher C; Ryder, Mabel M; Nishihara, Eijun E; Ghossein, Ronald A RA; Ladanyi, Marc M; Yamashita, Shunichi S; Mitsutake, Norisato N; Fagin, James A JA
Publication Date: 2012-05-01

Variant appearance in text: EGFR: 2126A>T; E709V
PubMed Link: 21717456
Variant Present in the following documents:
  • Main text
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Co-conserved features associated with cis regulation of ErbB tyrosine kinases.

Plos One
Mirza, Amar A; Mustafa, Morad M; Talevich, Eric E; Kannan, Natarajan N
Publication Date: 2010-12-13

Variant appearance in text: EGFR: E709V
PubMed Link: 21179209
Variant Present in the following documents:
  • Main text
  • pone.0014310.pdf
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A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes.

Bmc Cancer
Fumagalli, Debora D; Gavin, Patrick G PG; Taniyama, Yusuke Y; Kim, Seung-Il SI; Choi, Hyun-Joo HJ; Paik, Soonmyung S; Pogue-Geile, Katherine L KL
Publication Date: 2010-03-16

Variant appearance in text: EGFR: E709V
PubMed Link: 20233444
Variant Present in the following documents:
  • Main text
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Epidemiology of doublet/multiplet mutations in lung cancers: evidence that a subset arises by chronocoordinate events.

Plos One
Chen, Zhenbin Z; Feng, Jinong J; Buzin, Carolyn H CH; Sommer, Steve S SS
Publication Date: 2008

Variant appearance in text: EGFR: E709V
PubMed Link: 19005564
Variant Present in the following documents:
  • pone.0003714.s003.xls, sheet 1
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High tumour islet macrophage infiltration correlates with improved patient survival but not with EGFR mutations, gene copy number or protein expression in resected non-small cell lung cancer.

British Journal Of Cancer
Kim, D-W DW; Min, H S HS; Lee, K-H KH; Kim, Y J YJ; Oh, D-Y DY; Jeon, Y K YK; Lee, S-H SH; Im, S-A SA; Chung, D H DH; Kim, Y T YT; Kim, T-Y TY; Bang, Y-J YJ; Sung, S W SW; Kim, J H JH; Heo, D S DS
Publication Date: 2008-03-25

Variant appearance in text: EGFR: E709V
PubMed Link: 18283317
Variant Present in the following documents:
  • 6604256a.pdf
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Somatic mutations of the epidermal growth factor receptor and non-small-cell lung cancer.

Journal Of Medical Genetics
Zhang, Xiaozhu X; Chang, Alex A
Publication Date: 2007-03

Variant appearance in text: EGFR: E709V
PubMed Link: 17158592
Variant Present in the following documents:
  • Main text
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