EGFR c.2155G>C ;(p.G719R)

Variant ID: 7-55241707-G-C

NM_005228.3(EGFR):c.2155G>C;(p.G719R)

This variant was identified in 26 publications

View GRCh38 version.




Publications:


Blood tumor mutational burden and dynamic changes in circulating tumor DNA predict response to pembrolizumab treatment in advanced non-small cell lung cancer.

Translational Lung Cancer Research
Stensgaard, Simone S; Thomsen, Astrid A; Helstrup, Sofie S; Meldgaard, Peter P; Sorensen, Boe S BS
Publication Date: 2023-05-31

Variant appearance in text: EGFR: Gly719Arg
PubMed Link: 37323168
Variant Present in the following documents:
  • tlcr-12-05-971-supplementary.pdf
View BVdb publication page



Pan-cancer clinical impact of latent drivers from double mutations.

Communications Biology
Yavuz, Bengi Ruken BR; Tsai, Chung-Jung CJ; Nussinov, Ruth R; Tuncbag, Nurcan N
Publication Date: 2023-02-20

Variant appearance in text: EGFR: G719R
PubMed Link: 36808143
Variant Present in the following documents:
  • 42003_2023_4519_MOESM3_ESM.xlsx, sheet 3
View BVdb publication page



Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics
G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A
Publication Date: 2022

Variant appearance in text: EGFR: G719R
PubMed Link: 36561320
Variant Present in the following documents:
  • Table3.xlsx, sheet 1
  • Table2.xlsx, sheet 4
View BVdb publication page



Landscape of EGFR mutations in lung adenocarcinoma: a single institute experience with comparison of PANAMutyper testing and targeted next-generation sequencing.

Journal Of Pathology And Translational Medicine
Lee, Jeonghyo J; Han, Yeon Bi YB; Kwon, Hyun Jung HJ; Lee, Song Kook SK; Kim, Hyojin H; Chung, Jin-Haeng JH
Publication Date: 2022-09

Variant appearance in text: EGFR: 2155G>C; G719R
PubMed Link: 36128861
Variant Present in the following documents:
  • Main text
  • jptm-2022-06-11.pdf
View BVdb publication page



Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society
Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW
Publication Date: 2022-05-23

Variant appearance in text: EGFR: 2155G>C; Gly719Arg
PubMed Link: 35606799
Variant Present in the following documents:
  • 41021_2022_248_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Ultrasensitive analysis of genetic instability related to chemical exposure.

Journal Of Applied Genetics
Domoradzki, Tomasz T; Grochowski, Piotr P; Jaśkiewicz, Anna A; Pająk, Beata B
Publication Date: 2022-05

Variant appearance in text: EGFR: G719R
PubMed Link: 34967917
Variant Present in the following documents:
  • Main text
View BVdb publication page



Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine
Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z
Publication Date: 2021-10

Variant appearance in text: EGFR: Gly719Arg
PubMed Link: 34599863
Variant Present in the following documents:
  • CAM4-10-7360-s002.xlsx, sheet 2
View BVdb publication page



Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine
Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z
Publication Date: 2021-10

Variant appearance in text: EGFR: Gly719Arg
PubMed Link: 34599863
Variant Present in the following documents:
  • CAM4-10-7360-s002.xlsx, sheet 2
View BVdb publication page



Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports
Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O
Publication Date: 2020-10-13

Variant appearance in text: rs28929495
PubMed Link: 33051506
Variant Present in the following documents:
  • 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports
Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA
Publication Date: 2020-09-21

Variant appearance in text: EGFR: G719R
PubMed Link: 32958805
Variant Present in the following documents:
  • 41598_2020_72404_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



EGFR mutation status in a series of Turkish non-small cell lung cancer patients.

Biomedical Reports
Calibasi-Kocal, Gizem G; Amirfallah, Arsalan A; Sever, Tolga T; Umit Unal, Olcun O; Gurel, Duygu D; Oztop, Ilhan I; Ellidokuz, Hulya H; Basbinar, Yasemin Y
Publication Date: 2020-08

Variant appearance in text: EGFR: Gly719Arg
PubMed Link: 32509305
Variant Present in the following documents:
  • Main text
View BVdb publication page



Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non-small cell lung cancer: Analysis of over 8000 cases.

Cancer
Mack, Philip C PC; Banks, Kimberly C KC; Espenschied, Carin R CR; Burich, Rebekah A RA; Zill, Oliver A OA; Lee, Christine E CE; Riess, Jonathan W JW; Mortimer, Stefanie A SA; Talasaz, AmirAli A; Lanman, Richard B RB; Gandara, David R DR
Publication Date: 2020-07-15

Variant appearance in text: EGFR: G719R
PubMed Link: 32365229
Variant Present in the following documents:
  • Main text
  • CNCR-126-3219.pdf
View BVdb publication page



Inherited lung cancer: a review.

Ecancermedicalscience
de Alencar, Viviane Teixeira Loiola VTL; Formiga, Maria Nirvana MN; de Lima, Vladmir Cláudio Cordeiro VCC
Publication Date: 2020

Variant appearance in text: EGFR: G719R
PubMed Link: 32104210
Variant Present in the following documents:
  • can-14-1008.pdf
View BVdb publication page



A combined computational and experimental strategy identifies mutations conferring resistance to drugs targeting the BCR-ABL fusion protein.

Communications Biology
Liu, Jinxin J; Pei, Jianfeng J; Lai, Luhua L
Publication Date: 2020-01-09

Variant appearance in text: EGFR: G719R
PubMed Link: 31925328
Variant Present in the following documents:
  • Main text
View BVdb publication page



Detection of clinically relevant epidermal growth factor receptor pathway mutations in circulating cell-free tumor DNA using next generation sequencing in squamous cell carcinoma lung.

South Asian Journal Of Cancer
Govind, Kanakasetty Babu KB; Koppaka, Deepak D; Dasappa, Lokanatha L; Jacob, Linu Abraham LA; C Babu, Suresh M SM; Lokesh, N Kadabur NK; Haleshappa, Rudresha Antapura RA; Rajeev, L K LK; Saldanha, Smitha Carol SC; Abhishek, Anand A; Asati, Vikas V; Chethan, R R; Ramprasad, Vedam Laxmi VL
Publication Date: 2019

Variant appearance in text: EGFR: Gly719Arg
PubMed Link: 31807490
Variant Present in the following documents:
  • Main text
  • SAJC-8-247.pdf
View BVdb publication page



Targeted therapies for non-HPV-related head and neck cancer: challenges and opportunities in the context of predictive, preventive, and personalized medicine.

The Epma Journal
Shahoumi, Linah A LA; Yeudall, W Andrew WA
Publication Date: 2019-09

Variant appearance in text: EGFR: G719R
PubMed Link: 31462945
Variant Present in the following documents:
  • Main text
View BVdb publication page



Co-mutational assessment of circulating tumour DNA (ctDNA) during osimertinib treatment for T790M mutant lung cancer.

Journal Of Cellular And Molecular Medicine
Xing, Puyuan P; Han, Xiaohong X; Wang, Sha S; Liu, Yutao Y; Yang, Sheng S; Hao, Xuezhi X; Wang, Yan Y; Liu, Peng P; Li, Junling J; Wang, Lin L; Chang, Lianpeng L; Guan, Yanfang Y; Zhang, Zhishang Z; Wu, Di D; Yao, Jiarui J; Yi, Xin X; Shi, Yuankai Y
Publication Date: 2019-10

Variant appearance in text: EGFR: G719R
PubMed Link: 31393074
Variant Present in the following documents:
  • Main text
  • JCMM-23-6812.pdf
View BVdb publication page



Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours.

Oncotarget
Izquierdo, Elisa E; Yuan, Lina L; George, Sally S; Hubank, Michael M; Jones, Chris C; Proszek, Paula P; Shipley, Janet J; Gatz, Susanne A SA; Stinson, Caedyn C; Moore, Andrew S AS; Clifford, Steven C SC; Hicks, Debbie D; Lindsey, Janet C JC; Hill, Rebecca M RM; Jacques, Thomas S TS; Chalker, Jane J; Thway, Khin K; O'Connor, Simon S; Marshall, Lynley L; Moreno, Lucas L; Pearson, Andrew A; Chesler, Louis L; Walker, Brian A BA; De Castro, David Gonzalez DG
Publication Date: 2017-12-19

Variant appearance in text: rs28929495
PubMed Link: 29340109
Variant Present in the following documents:
  • oncotarget-08-112036-s003.xlsx, sheet 1
View BVdb publication page



The detectability of the pretreatment EGFR T790M mutations in lung adenocarcinoma using CAST-PCR and digital PCR.

Journal Of Thoracic Disease
Tatematsu, Tsutomu T; Okuda, Katsuhiro K; Suzuki, Ayumi A; Oda, Risa R; Sakane, Tadashi T; Kawano, Osamu O; Haneda, Hiroshi H; Moriyama, Satoru S; Sasaki, Hidefumi H; Nakanishi, Ryoichi R
Publication Date: 2017-08

Variant appearance in text: EGFR: G719R
PubMed Link: 28932544
Variant Present in the following documents:
  • Main text
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: rs28929495
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page



Rational design of non-resistant targeted cancer therapies.

Scientific Reports
Martínez-Jiménez, Francisco F; Overington, John P JP; Al-Lazikani, Bissan B; Marti-Renom, Marc A MA
Publication Date: 2017-04-24

Variant appearance in text: EGFR: G719R
PubMed Link: 28436422
Variant Present in the following documents:
  • Main text
  • srep46632.pdf
View BVdb publication page



Publication of nuclear magnetic resonance experimental data with semantic web technology and the application thereof to biomedical research of proteins.

Journal Of Biomedical Semantics
Yokochi, Masashi M; Kobayashi, Naohiro N; Ulrich, Eldon L EL; Kinjo, Akira R AR; Iwata, Takeshi T; Ioannidis, Yannis E YE; Livny, Miron M; Markley, John L JL; Nakamura, Haruki H; Kojima, Chojiro C; Fujiwara, Toshimichi T
Publication Date: 2016-05-05

Variant appearance in text: rs28929495
PubMed Link: 27927232
Variant Present in the following documents:
  • 13326_2016_57_MOESM1_ESM.pdf
View BVdb publication page



Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One
Holehouse, Alex S AS; Naegle, Kristen M KM
Publication Date: 2015

Variant appearance in text: rs28929495
PubMed Link: 26659599
Variant Present in the following documents:
  • pone.0144692.s002.xlsx, sheet 1
View BVdb publication page



EGFR molecular testing in African-American non-small cell lung cancer patients - a review of discrepant data.

Translational Lung Cancer Research
Clifford, Bradley T BT; Fu, Pingfu P; Pennell, Nathan A NA; Halmos, Balazs B; Leidner, Rom S RS
Publication Date: 2013-06

Variant appearance in text: EGFR: G719R
PubMed Link: 25806239
Variant Present in the following documents:
  • Main text
View BVdb publication page



[Advances of driver gene and targeted therapy of non-small cell lung cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Zhang, Dan D; Huang, Yan Y; Wang, Hongyang H
Publication Date: 2014-10-20

Variant appearance in text: EGFR: G719R
PubMed Link: 25342042
Variant Present in the following documents:
  • Main text
  • zgfazz-17-10-750.pdf
View BVdb publication page