EGFR c.2175G>A ;(p.T725=)

Variant ID: 7-55241727-G-A

NM_005228.3(EGFR):c.2175G>A;(p.T725=)

This variant was identified in 14 publications

View GRCh38 version.




Publications:


Identifying potential ligand molecules EGFR mediated TNBC targeting the kinase domain-identification of customized drugs through in silico methods.

Research In Pharmaceutical Sciences
Vyshnavi, Hima H; Namboori, Krishnan K
Publication Date: 2023-04

Variant appearance in text: rs55959834
PubMed Link: 36873279
Variant Present in the following documents:
  • Main text
  • RPS-18-121.pdf
View BVdb publication page



Clinicopathologic Characteristics of Grade 2/3 Meningiomas: A Perspective on the Role of Next-Generation Sequencing.

Frontiers In Oncology
Kim, Junhyung J; Hwang, Kihwan K; Kwon, Hyun Jung HJ; Lee, Ji Eun JE; Lee, Kyu Sang KS; Choe, Gheeyoung G; Han, Jung Ho JH; Kim, Chae-Yong CY
Publication Date: 2022

Variant appearance in text: N/A
PubMed Link: 35774130
Variant Present in the following documents:
View BVdb publication page



Identifying Actionable Variants Using Capture-Based Targeted Sequencing in 563 Patients With Non-Small Cell Lung Carcinoma.

Frontiers In Oncology
Jiang, Haiping H; Wang, Yinan Y; Xu, Hanlin H; Lei, Wei W; Yu, Xiaoyun X; Tian, Haiying H; Meng, Cong C; Wang, Xueying X; Zhao, Zicheng Z; Jin, Xiangfeng X
Publication Date: 2021

Variant appearance in text: N/A
PubMed Link: 35186718
Variant Present in the following documents:
View BVdb publication page



Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (New York, N.Y.)
Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J
Publication Date: 2021-05-28

Variant appearance in text: EGFR: T725T
PubMed Link: 34557754
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (Cambridge (Mass.))
Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J
Publication Date: 2021-05-28

Variant appearance in text: EGFR: T725T
PubMed Link: 34557754
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Comprehensive omic characterization of breast cancer in Mexican-Hispanic women.

Nature Communications
Romero-Cordoba, Sandra L SL; Salido-Guadarrama, Ivan I; Rebollar-Vega, Rosa R; Bautista-Piña, Veronica V; Dominguez-Reyes, Carlos C; Tenorio-Torres, Alberto A; Villegas-Carlos, Felipe F; Fernández-López, Juan C JC; Uribe-Figueroa, Laura L; Alfaro-Ruiz, Luis L; Hidalgo-Miranda, Alfredo A
Publication Date: 2021-04-14

Variant appearance in text: EGFR: T725=
PubMed Link: 33854067
Variant Present in the following documents:
  • 41467_2021_22478_MOESM8_ESM.xlsx, sheet 9
View BVdb publication page



Peripheral type squamous cell carcinoma of the lung: clinicopathologic characteristics in comparison to the central type.

Journal Of Pathology And Translational Medicine
Sung, Yeoun Eun YE; Cho, Uiju U; Lee, Kyo Young KY
Publication Date: 2020-07

Variant appearance in text: EGFR: 2175G>A; Thr725Thr
PubMed Link: 32544984
Variant Present in the following documents:
  • Main text
  • jptm-2020-05-04.pdf
View BVdb publication page



Simultaneous targeting of HER family pro-survival signaling with Pan-HER antibody mixture is highly effective in TNBC: a preclinical trial with PDXs.

Breast Cancer Research : Bcr
Reddy, Tejaswini P TP; Choi, Dong S DS; Anselme, Ann C AC; Qian, Wei W; Chen, Wen W; Lantto, Johan J; Horak, Ivan D ID; Kragh, Michael M; Chang, Jenny C JC; Rosato, Roberto R RR
Publication Date: 2020-05-15

Variant appearance in text: EGFR: T725T
PubMed Link: 32414394
Variant Present in the following documents:
  • 13058_2020_1280_MOESM1_ESM.pdf
View BVdb publication page



Genetic Evidence Supporting the Role of the Calcium Channel, CACNA1S, in Tooth Cusp and Root Patterning.

Frontiers In Physiology
Laugel-Haushalter, Virginie V; Morkmued, Supawich S; Stoetzel, Corinne C; Geoffroy, Véronique V; Muller, Jean J; Boland, Anne A; Deleuze, Jean-François JF; Chennen, Kirsley K; Pitiphat, Waranuch W; Dollfus, Hélène H; Niederreither, Karen K; Bloch-Zupan, Agnès A; Pungchanchaikul, Patimaporn P
Publication Date: 2018

Variant appearance in text: EGFR: 2175G>A; rs55959834
PubMed Link: 30319441
Variant Present in the following documents:
  • Table_7.xlsx, sheet 1
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: T725T
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Whole-exome sequencing analysis of Waardenburg syndrome in a Chinese family.

Human Genome Variation
Chen, Dezhong D; Zhao, Na N; Wang, Jing J; Li, Zhuoyu Z; Wu, Changxin C; Fu, Jie J; Xiao, Han H
Publication Date: 2017

Variant appearance in text: rs55959834
PubMed Link: 28690861
Variant Present in the following documents:
  • hgv201727-s1.xls, sheet 1
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: N/A
PubMed Link: 28492226
Variant Present in the following documents:
View BVdb publication page



Clinical characteristics and response to tyrosine kinase inhibitors of patients with non-small cell lung cancer harboring uncommon epidermal growth factor receptor mutations.

Chinese Journal Of Cancer Research = Chung-Kuo Yen Cheng Yen Chiu
Zhang, Yan Y; Wang, Zheng Z; Hao, Xuezhi X; Hu, Xingsheng X; Wang, Hongyu H; Wang, Yan Y; Ying, Jianming J
Publication Date: 2017-02

Variant appearance in text: EGFR: T725T
PubMed Link: 28373750
Variant Present in the following documents:
  • Main text
  • cjcr-29-1-18.pdf
View BVdb publication page



Whole-genome sequencing of the world's oldest people.

Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Publication Date: 2014

Variant appearance in text: N/A
PubMed Link: 25390934
Variant Present in the following documents:
View BVdb publication page



The human epidermal growth factor receptor (EGFR) gene in European patients with advanced colorectal cancer harbors infrequent mutations in its tyrosine kinase domain.

Bmc Medical Genetics
Metzger, Brigitte B; Chambeau, Laetitia L; Begon, Dominique Y DY; Faber, Carlo C; Kayser, Jacques J; Berchem, Guy G; Pauly, Marc M; Boniver, Jacques J; Delvenne, Philippe P; Dicato, Mario M; Wenner, Thomas T
Publication Date: 2011-10-25

Variant appearance in text: EGFR: T725T
PubMed Link: 22026926
Variant Present in the following documents:
  • 1471-2350-12-144.pdf
View BVdb publication page