Publications:

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Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: P741S

PubMed Link: 35304574

Variant Present in the following documents:

• 41388_2022_Article_2263.pdf

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Integrative Bioinformatics approaches to therapeutic gene target selection in various cancers for Nitroglycerin.

Scientific Reports

Chinnappan, Jayaprakash J; Ramu, Akilandeswari A; V, Vidhya Rajalakshmi VR; S, Akil Kavya AK

Publication Date: 2021-11-11

Variant appearance in text: EGFR: P741S

PubMed Link: 34764329

Variant Present in the following documents:

• Main text
• 41598_2021_Article_1508.pdf

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Characterization of epidermal growth factor receptor (EGFR) P848L, an unusual EGFR variant present in lung cancer patients, in a murine Ba/F3 model.

Febs Open Bio

Sarcar, Bhaswati B; Gimbrone, Nicholas T NT; Wright, Gabriela G; Remsing Rix, Lily L LL; Gordian, Edna R ER; Rix, Uwe U; Chiappori, Alberto A AA; Reuther, Gary W GW; Santiago-Cardona, Pedro G PG; Muñoz-Antonia, Teresita T; Cress, William Douglas WD

Publication Date: 2019-10

Variant appearance in text: EGFR: P741S

PubMed Link: 31314158

Variant Present in the following documents:

• Main text
• FEB4-9-1689.pdf

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: EGFR: P741S

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 3

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Epidermal growth factor receptor somatic mutation analysis in 354 Chinese patients with non-small cell lung cancer.

Oncology Letters

Quan, Xueping X; Gao, Hongjun H; Wang, Zhikuan Z; Li, Jie J; Zhao, Wentao W; Liang, Wei W; Yu, Qiang Q; Guo, Dongliang D; Hao, Zhanping Z; Liu, Jingxin J

Publication Date: 2018-02

Variant appearance in text: EGFR: P741S

PubMed Link: 29434916

Variant Present in the following documents:

• Main text
• ol-15-02-2131.pdf

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Circulating-free DNA Mutation Associated with Response of Targeted Therapy in Human Epidermal Growth Factor Receptor 2-positive Metastatic Breast Cancer.

Chinese Medical Journal

Ye, Qing Q; Qi, Fan F; Bian, Li L; Zhang, Shao-Hua SH; Wang, Tao T; Jiang, Ze-Fei ZF

Publication Date: 2017-03-05

Variant appearance in text: EGFR: P741S

PubMed Link: 28229982

Variant Present in the following documents:

• CMJ-130-522.pdf

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Spatio-temporal mutation profiles of case-matched colorectal carcinomas and their metastases reveal unique de novo mutations in metachronous lung metastases by targeted next generation sequencing.

Molecular Cancer

Kovaleva, Valentina V; Geissler, Anna-Lena AL; Lutz, Lisa L; Fritsch, Ralph R; Makowiec, Frank F; Wiesemann, Sebastian S; Hopt, Ulrich T UT; Passlick, Bernward B; Werner, Martin M; Lassmann, Silke S

Publication Date: 2016-10-18

Variant appearance in text: EGFR: 2221C>T; Pro741Ser

PubMed Link: 27756406

Variant Present in the following documents:

• 12943_2016_549_MOESM2_ESM.xlsx, sheet 1

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Tyr1068-phosphorylated epidermal growth factor receptor (EGFR) predicts cancer stem cell targeting by erlotinib in preclinical models of wild-type EGFR lung cancer.

Cell Death & Disease

Sette, G G; Salvati, V V; Mottolese, M M; Visca, P P; Gallo, E E; Fecchi, K K; Pilozzi, E E; Duranti, E E; Policicchio, E E; Tartaglia, M M; Milella, M M; De Maria, R R; Eramo, A A

Publication Date: 2015-08-06

Variant appearance in text: EGFR: P741S

PubMed Link: 26247735

Variant Present in the following documents:

• Main text
• cddis2015217a.pdf

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Aberrations in the epidermal growth factor receptor gene in 958 patients with diverse advanced tumors: implications for therapy.

Annals Of Oncology : Official Journal Of The European Society For Medical Oncology

Wheler, J J JJ; Falchook, G S GS; Tsimberidou, A M AM; Hong, D S DS; Naing, A A; Piha-Paul, S A SA; Chen, S S SS; Fu, S S; Stephen, B B; Fok, J Y JY; Janku, F F; Kurzrock, R R

Publication Date: 2013-03

Variant appearance in text: EGFR: P741S

PubMed Link: 23139256

Variant Present in the following documents:

• Main text

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