EGFR c.2230A>G ;(p.I744V)

Variant ID: 7-55242460-A-G

NM_005228.3(EGFR):c.2230A>G;(p.I744V)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications
Boström, Martin M; Larsson, Erik E
Publication Date: 2022-11-17

Variant appearance in text: EGFR: I744V
PubMed Link: 36396655
Variant Present in the following documents:
  • 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Spatially interacting phosphorylation sites and mutations in cancer.

Nature Communications
Huang, Kuan-Lin KL; Scott, Adam D AD; Zhou, Daniel Cui DC; Wang, Liang-Bo LB; Weerasinghe, Amila A; Elmas, Abdulkadir A; Liu, Ruiyang R; Wu, Yige Y; Wendl, Michael C MC; Wyczalkowski, Matthew A MA; Baral, Jessika J; Sengupta, Sohini S; Lai, Chin-Wen CW; Ruggles, Kelly K; Payne, Samuel H SH; Raphael, Benjamin B; Fenyö, David D; Chen, Ken K; Mills, Gordon G; Ding, Li L
Publication Date: 2021-04-19

Variant appearance in text: EGFR: I744V
PubMed Link: 33875650
Variant Present in the following documents:
  • 41467_2021_22481_MOESM4_ESM.xlsx, sheet 1
  • 41467_2021_22481_MOESM4_ESM.xlsx, sheet 5
  • 41467_2021_22481_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports
Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM
Publication Date: 2020-06-23

Variant appearance in text: EGFR: I744V
PubMed Link: 32579932
Variant Present in the following documents:
  • mmc5.xlsx, sheet 3
View BVdb publication page



Epidermal growth factor receptor somatic mutation analysis in 354 Chinese patients with non-small cell lung cancer.

Oncology Letters
Quan, Xueping X; Gao, Hongjun H; Wang, Zhikuan Z; Li, Jie J; Zhao, Wentao W; Liang, Wei W; Yu, Qiang Q; Guo, Dongliang D; Hao, Zhanping Z; Liu, Jingxin J
Publication Date: 2018-02

Variant appearance in text: EGFR: I744V
PubMed Link: 29434916
Variant Present in the following documents:
  • Main text
  • ol-15-02-2131.pdf
View BVdb publication page



EGFR with TKI-sensitive mutations in exon 19 is highly expressed and frequently detected in Chinese patients with lung squamous carcinoma.

Oncotargets And Therapy
Memon, Aadil Ahmed AA; Zhang, Haiping H; Gu, Ye Y; Luo, Qian Q; Shi, Jiajun J; Deng, Zixin Z; Ma, Jian J; Ma, Wei W
Publication Date: 2017

Variant appearance in text: EGFR: Ile744Val
PubMed Link: 29075127
Variant Present in the following documents:
  • Main text
  • ott-10-4607.pdf
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: ERBB: 2230A>G
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page



High-throughput detection of clinically targetable alterations using next-generation sequencing.

Oncotarget
Vendrell, Julie A JA; Grand, David D; Rouquette, Isabelle I; Costes, Valérie V; Icher, Samira S; Selves, Janick J; Larrieux, Marion M; Barbe, Aurore A; Brousset, Pierre P; Solassol, Jérôme J
Publication Date: 2017-06-20

Variant appearance in text: EGFR: 2230A>G; Ile744Val
PubMed Link: 28404952
Variant Present in the following documents:
  • Main text
  • oncotarget-08-40345.pdf
View BVdb publication page



Impact of EGFR mutation detection methods on the efficacy of erlotinib in patients with advanced EGFR-wild type lung adenocarcinoma.

Plos One
Tseng, Jeng-Sen JS; Wang, Chih-Liang CL; Huang, Ming-Shyan MS; Chen, Chung-Yu CY; Chang, Cheng-Yu CY; Yang, Tsung-Ying TY; Tsai, Chi-Ren CR; Chen, Kun-Chieh KC; Hsu, Kuo-Hsuan KH; Tsai, Meen-Hsin MH; Yu, Sung-Liang SL; Su, Kang-Yi KY; Wu, Chih-Wei CW; Yang, Cheng-Ta CT; Chen, Yuh-Min YM; Chang, Gee-Chen GC
Publication Date: 2014

Variant appearance in text: EGFR: I744V
PubMed Link: 25215536
Variant Present in the following documents:
  • pone.0107160.s004.pdf
View BVdb publication page



Prognostic and predictive value of epidermal growth factor receptor tyrosine kinase domain mutation status and gene copy number for adjuvant chemotherapy in non-small cell lung cancer.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer
Tsao, Ming-Sound MS; Sakurada, Akira A; Ding, Keyue K; Aviel-Ronen, Sarit S; Ludkovski, Olga O; Liu, Ni N; Le Maître, Aurélie A; Gandara, David D; Johnson, David H DH; Rigas, James R JR; Seymour, Lesley L; Shepherd, Frances A FA
Publication Date: 2011-01

Variant appearance in text: EGFR: I744V
PubMed Link: 21107284
Variant Present in the following documents:
  • Main text
View BVdb publication page