EGFR c.2233_2234delinsGC ;(p.K745A)

Variant ID: 7-55242463-AA-GC

NM_005228.3(EGFR):c.2233_2234delinsGC;(p.K745A)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Epidermal growth factor receptor modulates hepatitis e virus entry in human hepatocytes -HEP-22-1113.

Hepatology (Baltimore, Md.)
Schrader, Jil Alexandra JA; Burkard, Thomas Leon TL; Brüggemann, Yannick Y; Gömer, André A; Meister, Toni Luise TL; Fu, Rebecca Menhua RM; Mehnert, Ann-Kathrin AK; Dao Thi, Viet Loan VL; Behrendt, Patrick P; Durantel, David D; Broering, Ruth R; Vondran, Florian W R FWR; Todt, Daniel D; Kinast, Volker V; Steinmann, Eike E
Publication Date: 2023-02-07

Variant appearance in text: EGFR: K745A
PubMed Link: 36745934
Variant Present in the following documents:
  • Main text
  • hep-77-2104.pdf
View BVdb publication page



Computational Prediction of Resistance Induced Alanine-Mutation in ATP Site of Epidermal Growth Factor Receptor.

International Journal Of Molecular Sciences
Amelia, Tasia T; Setiawan, Aderian Novito AN; Kartasasmita, Rahmana Emran RE; Ohwada, Tomohiko T; Tjahjono, Daryono Hadi DH
Publication Date: 2022-12-13

Variant appearance in text: EGFR: K745A
PubMed Link: 36555475
Variant Present in the following documents:
  • Main text
  • ijms-23-15828.pdf
View BVdb publication page



Fluorescence Imaging of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance in Non-Small Cell Lung Cancer.

Cancers
Martin-Fernandez, Marisa L ML
Publication Date: 2022-01-28

Variant appearance in text: EGFR: K745A
PubMed Link: 35158954
Variant Present in the following documents:
  • Main text
  • cancers-14-00686.pdf
View BVdb publication page



Fluorescence Imaging of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Resistance in Non-Small Cell Lung Cancer.

Cancers
Martin-Fernandez, Marisa L ML
Publication Date: 2022-01-28

Variant appearance in text: EGFR: K745A
PubMed Link: 35158954
Variant Present in the following documents:
  • Main text
  • cancers-14-00686.pdf
View BVdb publication page



Discovery of a novel EGFR ligand DPBA that degrades EGFR and suppresses EGFR-positive NSCLC growth.

Signal Transduction And Targeted Therapy
Yao, Nan N; Wang, Chen-Ran CR; Liu, Ming-Qun MQ; Li, Ying-Jie YJ; Chen, Wei-Min WM; Li, Zheng-Qiu ZQ; Qi, Qi Q; Lu, Jin-Jian JJ; Fan, Chun-Lin CL; Chen, Min-Feng MF; Qi, Ming M; Li, Xiao-Bo XB; Hong, Jian J; Zhang, Dong-Mei DM; Ye, Wen-Cai WC
Publication Date: 2020-10-09

Variant appearance in text: EGFR: K745A
PubMed Link: 33033232
Variant Present in the following documents:
  • Main text
  • 41392_2020_Article_251.pdf
View BVdb publication page



The architecture of EGFR's basal complexes reveals autoinhibition mechanisms in dimers and oligomers.

Nature Communications
Zanetti-Domingues, Laura C LC; Korovesis, Dimitrios D; Needham, Sarah R SR; Tynan, Christopher J CJ; Sagawa, Shiori S; Roberts, Selene K SK; Kuzmanic, Antonija A; Ortiz-Zapater, Elena E; Jain, Purvi P; Roovers, Rob C RC; Lajevardipour, Alireza A; van Bergen En Henegouwen, Paul M P PMP; Santis, George G; Clayton, Andrew H A AHA; Clarke, David T DT; Gervasio, Francesco L FL; Shan, Yibing Y; Shaw, David E DE; Rolfe, Daniel J DJ; Parker, Peter J PJ; Martin-Fernandez, Marisa L ML
Publication Date: 2018-10-18

Variant appearance in text: EGFR: K745A
PubMed Link: 30337523
Variant Present in the following documents:
  • 41467_2018_6632_MOESM1_ESM.pdf
View BVdb publication page



Mitochondrial translocation of EGFR regulates mitochondria dynamics and promotes metastasis in NSCLC.

Oncotarget
Che, Ting-Fang TF; Lin, Ching-Wen CW; Wu, Yi-Ying YY; Chen, Yu-Ju YJ; Han, Chia-Li CL; Chang, Yih-leong YL; Wu, Chen-Tu CT; Hsiao, Tzu-Hung TH; Hong, Tse-Ming TM; Yang, Pan-Chyr PC
Publication Date: 2015-11-10

Variant appearance in text: EGFR: K745A
PubMed Link: 26497368
Variant Present in the following documents:
  • Main text
  • oncotarget-06-37349.pdf
View BVdb publication page



Bisphosphonates inactivate human EGFRs to exert antitumor actions.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Yuen, Tony T; Stachnik, Agnes A; Iqbal, Jameel J; Sgobba, Miriam M; Gupta, Yogesh Y; Lu, Ping P; Colaianni, Graziana G; Ji, Yaoting Y; Zhu, Ling-Ling LL; Kim, Se-Min SM; Li, Jianhua J; Liu, Peng P; Izadmehr, Sudeh S; Sangodkar, Jaya J; Bailey, Jack J; Latif, Yathin Y; Mujtaba, Shiraz S; Epstein, Solomon S; Davies, Terry F TF; Bian, Zhuan Z; Zallone, Alberta A; Aggarwal, Aneel K AK; Haider, Shozeb S; New, Maria I MI; Sun, Li L; Narla, Goutham G; Zaidi, Mone M
Publication Date: 2014-12-16

Variant appearance in text: EGFR: K745A
PubMed Link: 25453081
Variant Present in the following documents:
  • Main text
View BVdb publication page



Modeling oncogene addiction using RNA interference.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Rothenberg, S Michael SM; Engelman, Jeffrey A JA; Le, Sheila S; Riese, David J DJ; Haber, Daniel A DA; Settleman, Jeffrey J
Publication Date: 2008-08-26

Variant appearance in text: EGFR: K745A
PubMed Link: 18711136
Variant Present in the following documents:
  • Main text
View BVdb publication page