EGFR c.2234A>T ;(p.K745M)

Variant ID: 7-55242464-A-T

NM_005228.3(EGFR):c.2234A>T;(p.K745M)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


A rotamer relay information system in the epidermal growth factor receptor-drug complexes reveals clues to new paradigm in protein conformational change.

Computational And Structural Biotechnology Journal
Hameduh, Tareq T; Mokry, Michal M; Miller, Andrew D AD; Adam, Vojtech V; Heger, Zbynek Z; Haddad, Yazan Y
Publication Date: 2021

Variant appearance in text: EGFR: K745M
PubMed Link: 34667537
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: EGFR: K745M
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Targeted Next-Generation Sequencing Combined With Circulating-Free DNA Deciphers Spatial Heterogeneity of Resected Multifocal Hepatocellular Carcinoma.

Frontiers In Immunology
Lin, Jianzhen J; Zhao, Songhui S; Wang, Dongxu D; Song, Yang Y; Che, Yue Y; Yang, Xu X; Mao, Jinzhu J; Xie, Fucun F; Long, Junyu J; Bai, Yi Y; Yang, Xiaobo X; Zhang, Lei L; Bian, Jin J; Lu, Xin X; Sang, Xinting X; Pan, Jie J; Wang, Kai K; Zhao, Haitao H
Publication Date: 2021

Variant appearance in text: EGFR: 2234A>T
PubMed Link: 34211467
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: EGFR: K745M
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



Pockets as structural descriptors of EGFR kinase conformations.

Plos One
Hasenahuer, Marcia Anahi MA; Barletta, German Patricio GP; Fernandez-Alberti, Sebastián S; Parisi, Gustavo G; Fornasari, María Silvina MS
Publication Date: 2017

Variant appearance in text: EGFR: K745M
PubMed Link: 29228029
Variant Present in the following documents:
  • pone.0189147.s003.xls, sheet 1
View BVdb publication page



The interactome of a PTB domain-containing adapter protein, Odin, revealed by SILAC.

Journal Of Proteomics
Zhong, Jun J; Chaerkady, Raghothama R; Kandasamy, Kumaran K; Gucek, Marjan M; Cole, Robert N RN; Pandey, Akhilesh A
Publication Date: 2011-03-01

Variant appearance in text: EGFR: K745M
PubMed Link: 21081186
Variant Present in the following documents:
  • Main text
View BVdb publication page