EGFR c.2235G>A ;(p.K745=)

Variant ID: 7-55242465-G-A

NM_005228.3(EGFR):c.2235G>A;(p.K745=)

This variant was identified in 9 publications

View GRCh38 version.




Publications:


Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: EGFR: K745k
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 2
View BVdb publication page



Predictive mutation signature of immunotherapy benefits in NSCLC based on machine learning algorithms.

Frontiers In Immunology
Liu, Zhichao Z; Lin, Guo G; Yan, Zeping Z; Li, Linduo L; Wu, Xingchen X; Shi, Jingrong J; He, Jianxing J; Zhao, Lei L; Liang, Hengrui H; Wang, Wei W
Publication Date: 2022

Variant appearance in text: EGFR: 2235G>A; K745K
PubMed Link: 36238300
Variant Present in the following documents:
  • Table_1.xlsx, sheet 4
View BVdb publication page



EPHA5 mutation was associated with adverse outcome of atezolizumab treatment in late-stage non-small cell lung cancers.

Bmc Pulmonary Medicine
Li, Zhenxiang Z; Zhou, Qing Q; Wang, Qi Q; Wang, Haiyong H; Yue, Weiming W
Publication Date: 2022-09-19

Variant appearance in text: EGFR: 2235G>A; K745K
PubMed Link: 36123678
Variant Present in the following documents:
  • 12890_2022_2161_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Meta-Data Analysis to Explore the Hub of the Hub-Genes That Influence SARS-CoV-2 Infections Highlighting Their Pathogenetic Processes and Drugs Repurposing.

Vaccines
Mosharaf, Md Parvez MP; Kibria, Md Kaderi MK; Hossen, Md Bayazid MB; Islam, Md Ariful MA; Reza, Md Selim MS; Mahumud, Rashidul Alam RA; Alam, Khorshed K; Gow, Jeff J; Mollah, Md Nurul Haque MNH
Publication Date: 2022-08-03

Variant appearance in text: EGFR: LYS745LYS
PubMed Link: 36016137
Variant Present in the following documents:
  • vaccines-10-01248.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: K745K
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Anti-tumor efficacy of theliatinib in esophageal cancer patient-derived xenografts models with epidermal growth factor receptor (EGFR) overexpression and gene amplification.

Oncotarget
Ren, Yongxin Y; Zheng, Jianming J; Fan, Shiming S; Wang, Linfang L; Cheng, Min M; Shi, Dongxia D; Zhang, Wei W; Tang, Renxiang R; Yu, Ying Y; Jiao, Longxian L; Ni, Jun J; Yang, Haibin H; Cai, Huaqing H; Yin, Fang F; Chen, Yunxin Y; Zhou, Feng F; Zhang, Weihan W; Qing, Weiguo W; Su, Weiguo W
Publication Date: 2017-08-01

Variant appearance in text: EGFR: K745K
PubMed Link: 28881608
Variant Present in the following documents:
  • Main text
  • oncotarget-08-50832-s002.xlsx, sheet 1
  • oncotarget-08-50832.pdf
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: ERBB: 2235G>A
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page



Complex mutations & subpopulations of deletions at exon 19 of EGFR in NSCLC revealed by next generation sequencing: potential clinical implications.

Plos One
Marchetti, Antonio A; Del Grammastro, Maela M; Filice, Giampaolo G; Felicioni, Lara L; Rossi, Giulio G; Graziano, Paolo P; Sartori, Giuliana G; Leone, Alvaro A; Malatesta, Sara S; Iacono, Michele M; Guetti, Luigi L; Viola, Patrizia P; Mucilli, Felice F; Cuccurullo, Franco F; Buttitta, Fiamma F
Publication Date: 2012

Variant appearance in text: EGFR: 2235G>A
PubMed Link: 22848739
Variant Present in the following documents:
  • pone.0042164.s003.xls, sheet 1
View BVdb publication page



A panel of high resolution melting (HRM) technology-based assays with direct sequencing possibility for effective mutation screening of EGFR and K-ras genes.

Cellular Oncology : The Official Journal Of The International Society For Cellular Oncology
Heideman, D A M DA; Thunnissen, F B FB; Doeleman, M M; Kramer, D D; Verheul, H M HM; Smit, E F EF; Postmus, P E PE; Meijer, C J L M CJ; Meijer, G A GA; Snijders, P J F PJ
Publication Date: 2009

Variant appearance in text: EGFR: K745K
PubMed Link: 19759413
Variant Present in the following documents:
  • ACP-2009-31-5-465850.pdf
View BVdb publication page