EGFR c.2236_2249del ;(p.E746Nfs*12)

Variant ID: 7-55242466-GGAATTAAGAGAAGC-G

NM_005228.3(EGFR):c.2236_2249del;(p.E746Nfs*12)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Integrative Bioinformatics approaches to therapeutic gene target selection in various cancers for Nitroglycerin.

Scientific Reports
Chinnappan, Jayaprakash J; Ramu, Akilandeswari A; V, Vidhya Rajalakshmi VR; S, Akil Kavya AK
Publication Date: 2021-11-11

Variant appearance in text: N/A
PubMed Link: 34764329
Variant Present in the following documents:
View BVdb publication page



Unveiling mutational dynamics in non-small cell lung cancer patients by quantitative EGFR profiling in vesicular RNA.

Molecular Oncology
Pasini, Luigi L; Notarangelo, Michela M; Vagheggini, Alessandro A; Burgio, Marco Angelo MA; Crinò, Lucio L; Chiadini, Elisa E; Prochowski, Andrea Iamurri AI; Delmonte, Angelo A; Ulivi, Paola P; D'Agostino, Vito Giuseppe VG
Publication Date: 2021-09

Variant appearance in text: EGFR: 2236_2249del
PubMed Link: 33942501
Variant Present in the following documents:
  • Main text
View BVdb publication page



Next‑generation sequencing‑based detection of EGFR, KRAS, BRAF, NRAS, PIK3CA, Her‑2 and TP53 mutations in patients with non‑small cell lung cancer.

Molecular Medicine Reports
Jing, Changwen C; Mao, Xuhua X; Wang, Zhuo Z; Sun, Kejing K; Ma, Rong R; Wu, Jianzhong J; Cao, Haixia H
Publication Date: 2018-08

Variant appearance in text: EGFR: 2236_2249del; E746fs
PubMed Link: 29956783
Variant Present in the following documents:
  • Main text
  • mmr-18-02-2191.pdf
View BVdb publication page



Molecular characteristics and clinical outcomes of EGFR exon 19 indel subtypes to EGFR TKIs in NSCLC patients.

Oncotarget
Su, Jian J; Zhong, Wenzhao W; Zhang, Xuchao X; Huang, Ying Y; Yan, Honghong H; Yang, Jinji J; Dong, Zhongyi Z; Xie, Zhi Z; Zhou, Qing Q; Huang, Xiaosui X; Lu, Danxia D; Yan, Wenqing W; Wu, Yi-Long YL
Publication Date: 2017-12-19

Variant appearance in text: EGFR: 2236_2249del
PubMed Link: 29340050
Variant Present in the following documents:
  • Main text
  • oncotarget-08-111246.pdf
View BVdb publication page



Complex mutations & subpopulations of deletions at exon 19 of EGFR in NSCLC revealed by next generation sequencing: potential clinical implications.

Plos One
Marchetti, Antonio A; Del Grammastro, Maela M; Filice, Giampaolo G; Felicioni, Lara L; Rossi, Giulio G; Graziano, Paolo P; Sartori, Giuliana G; Leone, Alvaro A; Malatesta, Sara S; Iacono, Michele M; Guetti, Luigi L; Viola, Patrizia P; Mucilli, Felice F; Cuccurullo, Franco F; Buttitta, Fiamma F
Publication Date: 2012

Variant appearance in text: EGFR: 2236_2249del
PubMed Link: 22848739
Variant Present in the following documents:
  • pone.0042164.s003.xls, sheet 1
View BVdb publication page