Publications:

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Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Bmc Cancer

Xie, Jianjiang J; Yao, Weishen W; Chen, Lingxiu L; Zhu, Wenjun W; Liu, Qiang Q; Geng, Geng G; Fang, Jing J; Zhao, Yang Y; Xiao, Li L; Huang, Zhenhua Z; Zhao, Jing J

Publication Date: 2023-03-31

Variant appearance in text: EGFR: Leu747_Ser752del

PubMed Link: 37004022

Variant Present in the following documents:

• 12885_2023_10674_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Exon-18-EGFR Mutated Transformed Small-Cell Lung Cancer: A Case Report and Literature Review.

Current Oncology (Toronto, Ont.)

Digiacomo, Nunzio N; De Pas, Tommaso T; Rossi, Giovanna G; Bossi, Paola P; Stucchi, Erika E; Conforti, Fabio F; Cocorocchio, Emilia E; Laszlo, Daniele D; Pala, Laura L; Zattarin, Emma E; Catania, Chiara C

Publication Date: 2023-03-20

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 36975478

Variant Present in the following documents:

• Main text
• curroncol-30-00265.pdf

View BVdb publication page

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Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial.

Nature Medicine

Cascone, Tina T; Leung, Cheuk H CH; Weissferdt, Annikka A; Pataer, Apar A; Carter, Brett W BW; Godoy, Myrna C B MCB; Feldman, Hope H; William, William N WN; Xi, Yuanxin Y; Basu, Sreyashi S; Sun, Jing Jing JJ; Yadav, Shalini S SS; Rojas Alvarez, Frank R FR; Lee, Younghee Y; Mishra, Aditya K AK; Chen, Lili L; Pradhan, Monika M; Guo, Haiping H; Sinjab, Ansam A; Zhou, Nicolas N; Negrao, Marcelo V MV; Le, Xiuning X; Gay, Carl M CM; Tsao, Anne S AS; Byers, Lauren Averett LA; Altan, Mehmet M; Glisson, Bonnie S BS; Fossella, Frank V FV; Elamin, Yasir Y YY; Blumenschein, George G; Zhang, Jianjun J; Skoulidis, Ferdinandos F; Wu, Jia J; Mehran, Reza J RJ; Rice, David C DC; Walsh, Garrett L GL; Hofstetter, Wayne L WL; Rajaram, Ravi R; Antonoff, Mara B MB; Fujimoto, Junya J; Solis, Luisa M LM; Parra, Edwin R ER; Haymaker, Cara C; Wistuba, Ignacio I II; Swisher, Stephen G SG; Vaporciyan, Ara A AA; Lin, Heather Y HY; Wang, Jing J; Gibbons, Don L DL; Jack Lee, J J; Ajami, Nadim J NJ; Wargo, Jennifer A JA; Allison, James P JP; Sharma, Padmanee P; Kadara, Humam H; Heymach, John V JV; Sepesi, Boris B

Publication Date: 2023-03-16

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 36928818

Variant Present in the following documents:

• 41591_2022_2189_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery

Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI

Publication Date: 2023-03-02

Variant appearance in text: EGFR: 2239_2256del; L747_S752del; rs121913440

PubMed Link: 36862804

Variant Present in the following documents:

• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 6

View BVdb publication page

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Analysis of acquired resistance mechanisms to osimertinib in patients with EGFR-mutated advanced non-small cell lung cancer from the AURA3 trial.

Nature Communications

Chmielecki, Juliann J; Mok, Tony T; Wu, Yi-Long YL; Han, Ji-Youn JY; Ahn, Myung-Ju MJ; Ramalingam, Suresh S SS; John, Thomas T; Okamoto, Isamu I; Yang, James Chih-Hsin JC; Shepherd, Frances A FA; Bulusu, Krishna C KC; Laus, Gianluca G; Collins, Barbara B; Barrett, J Carl JC; Hartmaier, Ryan J RJ; Papadimitrakopoulou, Vassiliki V

Publication Date: 2023-02-27

Variant appearance in text: EGFR: 2239_2256delTTAAGAGAAGCAACATCT

PubMed Link: 36849516

Variant Present in the following documents:

• 41467_2023_35962_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: EGFR: 2239_2256del; Leu747_Ser752del

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Case report: olaparib use in metastatic lung adenocarcinoma with BRCA2 pathogenic variant.

Cold Spring Harbor Molecular Case Studies

Soon Jian Hao, Jonathan J; Hoai, Chan Sock CS; Weng, Daniel Tan Shao DTS; Ngeow, Joanne J; Chiang, Jianbang J

Publication Date: 2022-12

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 36577523

Variant Present in the following documents:

• supp_mcs.a006223_Supplemental_Material.pdf

View BVdb publication page

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: EGFR: 2239_2256delTTAAGAGAAGCAACATCT; L747_S752del

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 3
• Table_2.xlsx, sheet 2

View BVdb publication page

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Immunotherapy for bilateral multiple ground glass opacities: An exploratory study for synchronous multiple primary lung cancer.

Frontiers In Immunology

Xu, Lin L; Shi, Meiqi M; Wang, Siwei S; Li, Ming M; Yin, Wenda W; Zhang, Jingyuan J; Zhu, Jun J; Jiang, Feng F; Xia, Wenjia W; Qiu, Ninglei N; Zhang, Zhi Z; Huang, Jianfeng J; Ma, Zhifei Z; Meng, Fanchen F; Zhu, Hongyu H; Dong, Guozhang G; Wang, Jie J; Yin, Rong R

Publication Date: 2022

Variant appearance in text: EGFR: 2239_2256del; Leu747_Ser752del; rs121913440

PubMed Link: 36389707

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 2

View BVdb publication page

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Liquid biopsy using ascitic fluid and pleural effusion supernatants for genomic profiling in gastrointestinal and lung cancers.

Bmc Cancer

Wu, Huita H; Ji, Haonan H; Yang, Wenhui W; Zhang, Min M; Guo, Yifang Y; Li, Bangkai B; Wang, Jiayin J; Chen, Rongrong R; Chen, Yuan Y; Wang, Xin X

Publication Date: 2022-09-27

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 36167530

Variant Present in the following documents:

• 12885_2022_9922_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Landscape of EGFR mutations in lung adenocarcinoma: a single institute experience with comparison of PANAMutyper testing and targeted next-generation sequencing.

Journal Of Pathology And Translational Medicine

Lee, Jeonghyo J; Han, Yeon Bi YB; Kwon, Hyun Jung HJ; Lee, Song Kook SK; Kim, Hyojin H; Chung, Jin-Haeng JH

Publication Date: 2022-09

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 36128861

Variant Present in the following documents:

• jptm-2022-06-11-suppl1.pdf

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Allele-specific activation, enzyme kinetics, and inhibitor sensitivities of EGFR exon 19 deletion mutations in lung cancer.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Brown, Benjamin P BP; Zhang, Yun-Kai YK; Kim, Soyeon S; Finneran, Patrick P; Yan, Yingjun Y; Du, Zhenfang Z; Kim, Jiyoon J; Hartzler, Abigail Leigh AL; LeNoue-Newton, Michele L ML; Smith, Adam W AW; Meiler, Jens J; Lovly, Christine M CM

Publication Date: 2022-07-26

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 35867821

Variant Present in the following documents:

• pnas.2206588119.sapp.pdf

View BVdb publication page

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Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology

Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J

Publication Date: 2022

Variant appearance in text: EGFR: 2239_2256delTTAAGAGAAGCAACATCT; L747_S752del

PubMed Link: 35814426

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 2

View BVdb publication page

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: EGFR: 2239_2256delTTAAGAGAAGCAACATCT; L747_S752del

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

View BVdb publication page

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Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society

Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW

Publication Date: 2022-05-23

Variant appearance in text: EGFR: 2239_2256delTTAAGAGAAGCAACATCT; Leu747_Ser752del

PubMed Link: 35606799

Variant Present in the following documents:

• 41021_2022_248_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Altered splicing of ATG16-L1 mediates acquired resistance to tyrosine kinase inhibitors of EGFR by blocking autophagy in non-small cell lung cancer.

Molecular Oncology

Hatat, Anne-Sophie AS; Benoit-Pilven, Clara C; Pucciarelli, Amélie A; de Fraipont, Florence F; Lamothe, Lucie L; Perron, Pascal P; Rey, Amandine A; Levra, Matteo Giaj MG; Toffart, Anne-Claire AC; Auboeuf, Didier D; Eymin, Beatrice B; Gazzeri, Sylvie S

Publication Date: 2022-10

Variant appearance in text: EGFR: 2239_2256del

PubMed Link: 35593080

Variant Present in the following documents:

• MOL2-16-3490-s004.pdf

View BVdb publication page

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Molecular landscape and therapeutic alterations in Asian soft-tissue sarcoma patients.

Cancer Medicine

Gan, Meifu M; Zhang, Chen C; Qiu, Liqing L; Wang, Yue Y; Bao, Hua H; Yu, Ruoying R; Liu, Rui R; Wu, Xue X; Shao, Yang Y; Hou, Peifeng P; Fei, Zhenglei Z

Publication Date: 2022-11

Variant appearance in text: EGFR: 2239_2256delTTAAGAGAAGCAACATCT; L747_S752del

PubMed Link: 35586877

Variant Present in the following documents:

• CAM4-11-4070-s004.xlsx, sheet 1

View BVdb publication page

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Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L

Publication Date: 2022-03-10

Variant appearance in text: EGFR: 2239_2256delTTAAGAGAAGCAACATCT; L747_S752del

PubMed Link: 35273153

Variant Present in the following documents:

• 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Molecular genetic profiling of small cell lung carcinoma in a Chinese cohort.

Translational Cancer Research

Wang, Zeng Z; Jiang, Zhiming Z; Lu, Hongyang H

Publication Date: 2019-02

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 35116754

Variant Present in the following documents:

• Main text

View BVdb publication page

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Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics

Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y

Publication Date: 2022-01-15

Variant appearance in text: EGFR: 2239_2256del; Leu747_Ser752del

PubMed Link: 35031014

Variant Present in the following documents:

• Main text
• 12864_2021_8289_MOESM1_ESM.xlsx, sheet 1
• 12864_2021_Article_8289.pdf

View BVdb publication page

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Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics

Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y

Publication Date: 2022-01-15

Variant appearance in text: EGFR: 2239_2256del; Leu747_Ser752del

PubMed Link: 35031014

Variant Present in the following documents:

• Main text
• 12864_2021_8289_MOESM1_ESM.xlsx, sheet 1
• 12864_2021_Article_8289.pdf

View BVdb publication page

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Secondary myelodysplastic syndromes identified via next-generation sequencing in a non-small cell lung cancer patient.

Bmc Medical Genomics

Feng, Yongzhi Y; Chen, Xialin X; Jiang, Keran K; Zhang, Ding D; Tao, Feng F; Ni, Dan D; Zhang, Jun J; Wu, Lixin L; Cai, Jinping J; Jiang, Libin L; Yu, GenHua G; Shi, Lin L

Publication Date: 2021-12-20

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 34930266

Variant Present in the following documents:

• Main text
• 12920_2021_Article_1147.pdf

View BVdb publication page

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Secondary myelodysplastic syndromes identified via next-generation sequencing in a non-small cell lung cancer patient.

Bmc Medical Genomics

Feng, Yongzhi Y; Chen, Xialin X; Jiang, Keran K; Zhang, Ding D; Tao, Feng F; Ni, Dan D; Zhang, Jun J; Wu, Lixin L; Cai, Jinping J; Jiang, Libin L; Yu, GenHua G; Shi, Lin L

Publication Date: 2021-12-20

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 34930266

Variant Present in the following documents:

• Main text
• 12920_2021_Article_1147.pdf

View BVdb publication page

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Dynamic recurrence risk and adjuvant chemotherapy benefit prediction by ctDNA in resected NSCLC.

Nature Communications

Qiu, Bin B; Guo, Wei W; Zhang, Fan F; Lv, Fang F; Ji, Ying Y; Peng, Yue Y; Chen, Xiaoxi X; Bao, Hua H; Xu, Yang Y; Shao, Yang Y; Tan, Fengwei F; Xue, Qi Q; Gao, Shugeng S; He, Jie J

Publication Date: 2021-11-19

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 34799585

Variant Present in the following documents:

• 41467_2021_27022_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Dynamic recurrence risk and adjuvant chemotherapy benefit prediction by ctDNA in resected NSCLC.

Nature Communications

Qiu, Bin B; Guo, Wei W; Zhang, Fan F; Lv, Fang F; Ji, Ying Y; Peng, Yue Y; Chen, Xiaoxi X; Bao, Hua H; Xu, Yang Y; Shao, Yang Y; Tan, Fengwei F; Xue, Qi Q; Gao, Shugeng S; He, Jie J

Publication Date: 2021-11-19

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 34799585

Variant Present in the following documents:

• 41467_2021_27022_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Patients harboring uncommon EGFR exon 19 deletion-insertion mutations respond well to first-generation EGFR inhibitors and osimeritinib upon acquisition of T790M.

Bmc Cancer

Wang, Yurong Y; Zheng, Ruipan R; Hu, Peizhu P; Zhang, Ziheng Z; Shen, Shujing S; Li, Xingya X

Publication Date: 2021-11-13

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 34774017

Variant Present in the following documents:

• Main text
• 12885_2021_Article_8942.pdf

View BVdb publication page

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The immune microenvironment in EGFR- and ERBB2-mutated lung adenocarcinoma.

Esmo Open

Kirchner, M M; Kluck, K K; Brandt, R R; Volckmar, A-L AL; Penzel, R R; Kazdal, D D; Endris, V V; Neumann, O O; Seker-Cin, H H; Goldschmid, H H; Glade, J J; Allgäuer, M M; Kriegsmann, M M; Winter, H H; Muley, T T; Perner, S S; Frost, N N; Reck, M M; Fröhling, S S; Schirmacher, P P; Thomas, M M; Budczies, J J; Christopoulos, P P; Stenzinger, A A

Publication Date: 2021-10

Variant appearance in text: EGFR: Leu747_Ser752del

PubMed Link: 34487971

Variant Present in the following documents:

• mmc1.xlsx, sheet 1

View BVdb publication page

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Integrated Analysis of Genomic and Immunological Features in Lung Adenocarcinoma With Micropapillary Component.

Frontiers In Oncology

Zhang, Shirong S; Xu, Yang Y; Zhao, Pan P; Bao, Hua H; Wang, Xiyong X; Liu, Rui R; Xu, Rujun R; Xiang, Jingjing J; Jiang, Hong H; Yan, Junrong J; Wu, Xue X; Shao, Yang Y; Liang, Jiafeng J; Wu, Qiong Q; Zhang, Zhihao Z; Lu, Shun S; Ma, Shenglin S

Publication Date: 2021

Variant appearance in text: EGFR: 2239_2256delTTAAGAGAAGCAACATCT

PubMed Link: 34221970

Variant Present in the following documents:

• Table_3.xlsx, sheet 1

View BVdb publication page

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Dynamic Evaluation of Circulating miRNA Profile in EGFR-Mutated NSCLC Patients Treated with EGFR-TKIs.

Cells

Leonetti, Alessandro A; Capula, Mjriam M; Minari, Roberta R; Mazzaschi, Giulia G; Gregori, Alessandro A; El Hassouni, Btissame B; Papini, Filippo F; Bordi, Paola P; Verzè, Michela M; Avan, Amir A; Tiseo, Marcello M; Giovannetti, Elisa E

Publication Date: 2021-06-16

Variant appearance in text: EGFR: 2239_2256del

PubMed Link: 34208765

Variant Present in the following documents:

• Main text
• cells-10-01520.pdf

View BVdb publication page

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EGFR-Mutated Squamous Cell Lung Cancer and Its Association With Outcomes.

Frontiers In Oncology

Jin, Rui R; Peng, Ling L; Shou, Jiawei J; Wang, Jin J; Jin, Yin Y; Liang, Fei F; Zhao, Jing J; Wu, Mengmeng M; Li, Qin Q; Zhang, Bin B; Wu, Xiaoying X; Lan, Fen F; Xia, Lixia L; Yan, Junrong J; Shao, Yang Y; Stebbing, Justin J; Shen, Huahao H; Li, Wen W; Xia, Yang Y

Publication Date: 2021

Variant appearance in text: EGFR: 2239_2256delTTAAGAGAAGCAACATCT; L747_S752del

PubMed Link: 34195081

Variant Present in the following documents:

• Table_2.xlsx, sheet 2

View BVdb publication page

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Deciphering the immunosuppressive tumor microenvironment in ALK- and EGFR-positive lung adenocarcinoma.

Cancer Immunology, Immunotherapy : Cii

Budczies, Jan J; Kirchner, Martina M; Kluck, Klaus K; Kazdal, Daniel D; Glade, Julia J; Allgäuer, Michael M; Kriegsmann, Mark M; Heußel, Claus-Peter CP; Herth, Felix J FJ; Winter, Hauke H; Meister, Michael M; Muley, Thomas T; Goldmann, Torsten T; Fröhling, Stefan S; Wermke, Martin M; Waller, Cornelius F CF; Tufman, Amanda A; Reck, Martin M; Peters, Solange S; Schirmacher, Peter P; Thomas, Michael M; Christopoulos, Petros P; Stenzinger, Albrecht A

Publication Date: 2021-06-14

Variant appearance in text: EGFR: Leu747_Ser752del

PubMed Link: 34125345

Variant Present in the following documents:

• 262_2021_2981_MOESM1_ESM.pdf

View BVdb publication page

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Deciphering the immunosuppressive tumor microenvironment in ALK- and EGFR-positive lung adenocarcinoma.

Cancer Immunology, Immunotherapy : Cii

Budczies, Jan J; Kirchner, Martina M; Kluck, Klaus K; Kazdal, Daniel D; Glade, Julia J; Allgäuer, Michael M; Kriegsmann, Mark M; Heußel, Claus-Peter CP; Herth, Felix J FJ; Winter, Hauke H; Meister, Michael M; Muley, Thomas T; Goldmann, Torsten T; Fröhling, Stefan S; Wermke, Martin M; Waller, Cornelius F CF; Tufman, Amanda A; Reck, Martin M; Peters, Solange S; Schirmacher, Peter P; Thomas, Michael M; Christopoulos, Petros P; Stenzinger, Albrecht A

Publication Date: 2022-02

Variant appearance in text: EGFR: Leu747_Ser752del

PubMed Link: 34125345

Variant Present in the following documents:

• 262_2021_2981_MOESM1_ESM.pdf

View BVdb publication page

---

Sensitivity, specificity, and accuracy of a liquid biopsy approach utilizing molecular amplification pools.

Scientific Reports

Garcia, Jessica J; Kamps-Hughes, Nick N; Geiguer, Florence F; Couraud, Sébastien S; Sarver, Brice B; Payen, Léa L; Ionescu-Zanetti, Cristian C

Publication Date: 2021-05-24

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 34031447

Variant Present in the following documents:

• 41598_2021_89592_MOESM1_ESM.xlsx, sheet 3

View BVdb publication page

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Presentation of EGFR mutations in 162 family probands with multiple primary lung cancer.

Translational Lung Cancer Research

Li, Chunxiang C; Wang, Yalong Y; Su, Kai K; Liu, Yu Y; Wang, Liyu L; Zheng, Bo B; Yan, Na N; Yuan, Dawei D; Zhang, Yanxiang Y; Xue, Liyan L; Gao, Shugeng S; He, Jie J

Publication Date: 2021-04

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 34012789

Variant Present in the following documents:

• Main text

View BVdb publication page

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Evaluation of the Idylla ctEGFR mutation assay to detect EGFR mutations in plasma from patients with non-small cell lung cancers.

Scientific Reports

Gilson, Pauline P; Saurel, Chloé C; Salleron, Julia J; Husson, Marie M; Demange, Jessica J; Merlin, Jean-Louis JL; Harlé, Alexandre A

Publication Date: 2021-05-18

Variant appearance in text: EGFR: 2239_2256del

PubMed Link: 34006948

Variant Present in the following documents:

• 41598_2021_90091_MOESM2_ESM.pdf

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Routine Molecular Screening of Patients with Advanced Non-SmallCell Lung Cancer in Circulating Cell-Free DNA at Diagnosis and During Progression Using OncoBEAMTM EGFR V2 and NGS Technologies.

Molecular Diagnosis & Therapy

Garcia, Jessica J; Gauthier, Arnaud A; Lescuyer, Gaëlle G; Barthelemy, David D; Geiguer, Florence F; Balandier, Julie J; Edelstein, Daniel L DL; Jones, Frederick S FS; Holtrup, Frank F; Duruisseau, Mickael M; Grolleau, Emmanuel E; Rodriguez-Lafrasse, Claire C; Merle, Patrick P; Couraud, Sébastien S; Payen, Léa L

Publication Date: 2021-03

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 33660188

Variant Present in the following documents:

• 40291_2021_515_MOESM1_ESM.pdf

View BVdb publication page

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Assessment of Clinical Benefit of Integrative Genomic Profiling in Advanced Solid Tumors.

Jama Oncology

Cobain, Erin F EF; Wu, Yi-Mi YM; Vats, Pankaj P; Chugh, Rashmi R; Worden, Francis F; Smith, David C DC; Schuetze, Scott M SM; Zalupski, Mark M MM; Sahai, Vaibhav V; Alva, Ajjai A; Schott, Anne F AF; Caram, Megan E V MEV; Hayes, Daniel F DF; Stoffel, Elena M EM; Jacobs, Michelle F MF; Kumar-Sinha, Chandan C; Cao, Xuhong X; Wang, Rui R; Lucas, David D; Ning, Yu Y; Rabban, Erica E; Bell, Janice J; Camelo-Piragua, Sandra S; Udager, Aaron M AM; Cieslik, Marcin M; Lonigro, Robert J RJ; Kunju, Lakshmi P LP; Robinson, Dan R DR; Talpaz, Moshe M; Chinnaiyan, Arul M AM

Publication Date: 2021-04-01

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 33630025

Variant Present in the following documents:

• jamaoncol-e207987-s004.xlsx, sheet 2

View BVdb publication page

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Standardization of pleural effusion-based tumor mutation burden (TMB) estimation using capture-based targeted sequencing.

Annals Of Translational Medicine

Yu, Yongfeng Y; Shen, Lan L; Ji, Wenxiang W; Lu, Shun S

Publication Date: 2021-01

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 33569442

Variant Present in the following documents:

• Main text

View BVdb publication page

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Morphological, immunohistochemical, and genetic analyses of bronchiolar adenoma and its putative variants.

The Journal Of Pathology. Clinical Research

Shao, Jinchen J; Yin, Jiani C JC; Bao, Hairong H; Zhao, Ruiying R; Han, Yuchen Y; Zhu, Lei L; Wu, Xue X; Shao, Yang Y; Zhang, Jie J

Publication Date: 2021-05

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 33400370

Variant Present in the following documents:

• Main text
• CJP2-7-287.pdf

View BVdb publication page

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Morphological, immunohistochemical, and genetic analyses of bronchiolar adenoma and its putative variants.

The Journal Of Pathology. Clinical Research

Shao, Jinchen J; Yin, Jiani C JC; Bao, Hairong H; Zhao, Ruiying R; Han, Yuchen Y; Zhu, Lei L; Wu, Xue X; Shao, Yang Y; Zhang, Jie J

Publication Date: 2021-05

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 33400370

Variant Present in the following documents:

• Main text
• CJP2-7-287.pdf

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2239_2256delTTAAGAGAAGCAACATCT; L747_S752del

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
• 41467_2020_20162_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma.

Nature Communications

Wang, Siwei S; Du, Mulong M; Zhang, Jingyuan J; Xu, Weizhang W; Yuan, Qianyu Q; Li, Ming M; Wang, Jie J; Zhu, Hongyu H; Wang, Yuzhuo Y; Wang, Cheng C; Gong, Yuhua Y; Wang, Xiaonan X; Hu, Zhibin Z; Christiani, David C DC; Xu, Lin L; Shen, Hongbing H; Yin, Rong R

Publication Date: 2020-11-27

Variant appearance in text: EGFR: 2239_2256delTTAAGAGAAGCAACATCT; L747_S752del; rs121913440

PubMed Link: 33247113

Variant Present in the following documents:

• 41467_2020_19855_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Predicting osimertinib-treatment outcomes through EGFR mutant-fraction monitoring in the circulating tumor DNA of EGFR T790M-positive patients with non-small cell lung cancer (WJOG8815L).

Molecular Oncology

Sakai, Kazuko K; Takahama, Takayuki T; Shimokawa, Mototsugu M; Azuma, Koichi K; Takeda, Masayuki M; Kato, Terufumi T; Daga, Haruko H; Okamoto, Isamu I; Akamatsu, Hiroaki H; Teraoka, Shunsuke S; Ono, Akira A; Ohira, Tatsuo T; Yokoyama, Toshihide T; Yamamoto, Nobuyuki N; Nakagawa, Kazuhiko K; Nishio, Kazuto K

Publication Date: 2021-01

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 33131198

Variant Present in the following documents:

• MOL2-15-126-s007.xlsx, sheet 1

View BVdb publication page

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Comprehensive cross-platform comparison of methods for non-invasive EGFR mutation testing: results of the RING observational trial.

Molecular Oncology

Romero, Atocha A; Jantus-Lewintre, Eloisa E; García-Peláez, Beatriz B; Royuela, Ana A; Insa, Amelia A; Cruz, Patricia P; Collazo, Ana A; Pérez Altozano, Javier J; Vidal, Oscar Juan OJ; Diz, Pilar P; Cobo, Manuel M; Hernández, Berta B; Vázquez Estevez, Sergio S; Benítez, Gretel G; Guirado, Maria M; Majem, Margarita M; Bernabé, Reyes R; Ortega, Ana Laura AL; Blasco, Ana A; Bosch-Barrera, Joaquim J; Jurado, Jose M JM; García González, Jorge J; Viteri, Santiago S; Garcia Giron, Carlos C; Massutí, Bartomeu B; Lopez Martín, Ana A; Rodriguez-Festa, Alejandro A; Calabuig-Fariñas, Silvia S; Molina-Vila, Miguel Ángel MÁ; Provencio, Mariano M

Publication Date: 2021-01

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 33107189

Variant Present in the following documents:

• Main text
• MOL2-15-43-s002.xls, sheet 1

View BVdb publication page

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Mass Spectrometry as a Highly Sensitive Method for Specific Circulating Tumor DNA Analysis in NSCLC: A Comparison Study.

Cancers

Lamy, Pierre-Jean PJ; van der Leest, Paul P; Lozano, Nicolas N; Becht, Catherine C; Duboeuf, Frédérique F; Groen, Harry J M HJM; Hilgers, Werner W; Pourel, Nicolas N; Rifaela, Naomi N; Schuuring, Ed E; Alix-Panabières, Catherine C

Publication Date: 2020-10-16

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 33081150

Variant Present in the following documents:

• cancers-12-03002-s001.pdf

View BVdb publication page

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Oncogenic mutations within the β3-αC loop of EGFR/ERBB2/BRAF/MAP2K1 predict response to therapies.

Molecular Genetics & Genomic Medicine

Zhang, Biao B; Chen, Yongsheng Y; Dai, Pingping P; Yu, Haoda H; Ma, Jianhui J; Chen, Chen C; Zhang, Yan Y; Guan, Yanfang Y; Chen, Rongrong R; Liu, Tao T; Wang, Jiayin J; Yang, Ling L; Yi, Xin X; Xia, Xuefeng X; Ma, Haitao H

Publication Date: 2020-10

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 32757330

Variant Present in the following documents:

• Main text
• MGG3-8-e1395.pdf

View BVdb publication page

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Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine

Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y

Publication Date: 2020-08-01

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 32738923

Variant Present in the following documents:

• 12967_2020_2449_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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EGFR mutation genotypes affect efficacy and resistance mechanisms of osimertinib in T790M-positive NSCLC patients.

Translational Lung Cancer Research

Zheng, Qiufan Q; Huang, Yan Y; Zhao, Hongyun H; Yang, Yunpeng Y; Hong, Shaodong S; Hou, Xue X; Zhao, Yuanyuan Y; Ma, Yuxiang Y; Zhou, Ting T; Zhang, Yaxiong Y; Fang, Wenfeng W; Zhang, Li L

Publication Date: 2020-06

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 32676311

Variant Present in the following documents:

• tlcr-09-03-471.pdf

View BVdb publication page

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Comprehensive routine diagnostic screening to identify predictive mutations, gene amplifications, and microsatellite instability in FFPE tumor material.

Bmc Cancer

Steeghs, Elisabeth M P EMP; Kroeze, Leonie I LI; Tops, Bastiaan B J BBJ; van Kempen, Leon C LC; Ter Elst, Arja A; Kastner-van Raaij, Annemiek W M AWM; Hendriks-Cornelissen, Sandra J B SJB; Hermsen, Mandy J W MJW; Jansen, Erik A M EAM; Nederlof, Petra M PM; Schuuring, Ed E; Ligtenberg, Marjolijn J L MJL; Eijkelenboom, Astrid A

Publication Date: 2020-04-07

Variant appearance in text: EGFR: 2239_2256del

PubMed Link: 32264863

Variant Present in the following documents:

• 12885_2020_6785_MOESM2_ESM.xlsx, sheet 7

View BVdb publication page

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Targeted sequencing analysis of cell-free DNA from metastatic non-small-cell lung cancer patients: clinical and biological implications.

Translational Lung Cancer Research

Pasquale, Raffaella R; Forgione, Laura L; Roma, Cristin C; Fenizia, Francesca F; Bergantino, Francesca F; Rachiglio, Anna M AM; De Luca, Antonella A; Gallo, Marianna M; Maiello, Monica R MR; Palumbo, Giuliano G; Morabito, Alessandro A; Azzaro, Rosa R; Normanno, Nicola N

Publication Date: 2020-02

Variant appearance in text: EGFR: 2239_2256del

PubMed Link: 32206554

Variant Present in the following documents:

• Main text

View BVdb publication page

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Rapid EGFR mutation testing in lung cancer tissue samples using a fully automated system and single-use cartridge.

Practical Laboratory Medicine

Al-Turkmani, M Rabie MR; Suriawinata, Michael A MA; Deharvengt, Sophie J SJ; Green, Donald C DC; Black, Candice C CC; Shirai, Keisuke K; Dragnev, Konstantin H KH; Tsongalis, Gregory J GJ

Publication Date: 2020-05

Variant appearance in text: EGFR: 2239_2256del

PubMed Link: 32181314

Variant Present in the following documents:

• Main text

View BVdb publication page

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Rapid detection of EGFR mutations in decalcified lung cancer bone metastasis.

Journal Of Bone Oncology

Boureille, Antoine A; Ferraro-Peyret, Carole C; Pontarollo, Guillaume G; Confavreux, Cyrille C; Pialat, Jean-Baptiste JB; Isaac, Sylvie S; Forest, Fabien F; Yvorel, Violaine V; Watkin, Emmanuel E; Girard, Nicolas N; Brevet, Marie M

Publication Date: 2020-04

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 31956476

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Clinical feasibility of NGS liquid biopsy analysis in NSCLC patients.

Plos One

Papadopoulou, Eirini E; Tsoulos, Nikolaos N; Tsantikidi, Katerina K; Metaxa-Mariatou, Vasiliki V; Stamou, Pinelopi Eleftheria PE; Kladi-Skandali, Athina A; Kapeni, Evgenia E; Tsaousis, Georgios G; Pentheroudakis, George G; Petrakis, Dimitrios D; Lampropoulou, Dimitra Ioanna DI; Aravantinos, Gerasimos G; Varthalitis, Ioannis I; Kesisis, George G; Boukovinas, Ioannis I; Papakotoulas, Pavlos P; Katirtzoglou, Nikolaos N; Athanasiadis, Elias E; Stavridi, Flora F; Christodoulou, Christos C; Koumarianou, Anna A; Eralp, Yeşim Y; Nasioulas, George G

Publication Date: 2019

Variant appearance in text: EGFR: L747_S752del

PubMed Link: 31860648

Variant Present in the following documents:

• Main text

View BVdb publication page

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EGFR, KRAS, BRAF, ALK, and cMET genetic alterations in 1440 Sardinian patients with lung adenocarcinoma.

Bmc Pulmonary Medicine

Colombino, Maria M; Paliogiannis, Panagiotis P; Cossu, Antonio A; Santeufemia, Davide Adriano DA; , ; Sini, Maria Cristina MC; Casula, Milena M; Palomba, Grazia G; Manca, Antonella A; Pisano, Marina M; Doneddu, Valentina V; Palmieri, Giuseppe G

Publication Date: 2019-11-11

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 31711449

Variant Present in the following documents:

View BVdb publication page

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Patient-derived lung cancer organoids as in vitro cancer models for therapeutic screening.

Nature Communications

Kim, Minsuh M; Mun, Hyemin H; Sung, Chang Oak CO; Cho, Eun Jeong EJ; Jeon, Hye-Joon HJ; Chun, Sung-Min SM; Jung, Da Jung DJ; Shin, Tae Hoon TH; Jeong, Gi Seok GS; Kim, Dong Kwan DK; Choi, Eun Kyung EK; Jeong, Seong-Yun SY; Taylor, Alison M AM; Jain, Sejal S; Meyerson, Matthew M; Jang, Se Jin SJ

Publication Date: 2019-09-05

Variant appearance in text: EGFR: 2239_2256delTTAAGAGAAGCAACATCT; Leu747_Ser752del; rs121913440

PubMed Link: 31488816

Variant Present in the following documents:

• 41467_2019_11867_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Saliva-derived cfDNA is applicable for EGFR mutation detection but not for quantitation analysis in non-small cell lung cancer.

Thoracic Cancer

Ding, Shanshan S; Song, Xingguo X; Geng, Xinran X; Liu, Lele L; Ma, Hongxin H; Wang, Xiujuan X; Wei, Ling L; Xie, Li L; Song, Xianrang X

Publication Date: 2019-10

Variant appearance in text: EGFR: 2239_2256del

PubMed Link: 31441578

Variant Present in the following documents:

• Main text
• TCA-10-1973.pdf

View BVdb publication page

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Oncogenic driver mutations in Swiss never smoker patients with lung adenocarcinoma and correlation with clinicopathologic characteristics and outcome.

Plos One

Grosse, Claudia C; Soltermann, Alex A; Rechsteiner, Markus M; Grosse, Alexandra A

Publication Date: 2019

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 31386689

Variant Present in the following documents:

• Main text
• pone.0220691.pdf

View BVdb publication page

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Exosome-based detection of activating and resistance EGFR mutations from plasma of non-small cell lung cancer patients.

Oncotarget

Castellanos-Rizaldos, Elena E; Zhang, Xuan X; Tadigotla, Vasisht R VR; Grimm, Dominik G DG; Karlovich, Chris C; Raez, Luis E LE; Skog, Johan K JK

Publication Date: 2019-04-23

Variant appearance in text: EGFR: 2239_2256del

PubMed Link: 31080561

Variant Present in the following documents:

• Main text
• oncotarget-10-2911.pdf

View BVdb publication page

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Mutational profile of Brazilian lung adenocarcinoma unveils association of EGFR mutations with high Asian ancestry and independent prognostic role of KRAS mutations.

Scientific Reports

Leal, Letícia Ferro LF; de Paula, Flávia Escremim FE; De Marchi, Pedro P; de Souza Viana, Luciano L; Pinto, Gustavo Dix Junqueira GDJ; Carlos, Carolina Dias CD; Berardinelli, Gustavo Noriz GN; Miziara, José Elias JE; da Silva, Carlos Maciel CM; Silva, Eduardo Caetano Albino ECA; Pereira, Rui R; de Oliveira, Marco Antonio MA; Scapulatempo-Neto, Cristovam C; Reis, Rui Manuel RM

Publication Date: 2019-03-01

Variant appearance in text: EGFR: Leu747_Ser752del

PubMed Link: 30824880

Variant Present in the following documents:

• Main text

View BVdb publication page

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Analysis of the frequency of oncogenic driver mutations and correlation with clinicopathological characteristics in patients with lung adenocarcinoma from Northeastern Switzerland.

Diagnostic Pathology

Grosse, Alexandra A; Grosse, Claudia C; Rechsteiner, Markus M; Soltermann, Alex A

Publication Date: 2019-02-11

Variant appearance in text: EGFR: 2239_2256del; L747_S752del

PubMed Link: 30744664

Variant Present in the following documents:

• Main text
• 13000_2019_Article_789.pdf

View BVdb publication page

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