Publications:

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Durable response to afatinib rechallenge in a long-term survivor of non-small cell lung cancer harboring EGFR L858R and L747V mutations.

Thoracic Cancer

Kanbe, Mio M; Sunaga, Noriaki N; Hara, Kenichiro K; Sawada, Hiiru H; Wakamatsu, Ikuo I; Hara, Kentaro K; Muto, Sohei S; Sawada, Yuri Y; Masubuchi, Hiroaki H; Sato, Mari M; Miura, Yosuke Y; Tsurumaki, Hiroaki H; Yatomi, Masakiyo M; Sakurai, Reiko R; Koga, Yasuhiko Y; Ohtaki, Yoichi Y; Nagashima, Toshiteru T; Okano, Naoko N; Kubo, Nobuteru N; Maeno, Toshitaka T; Hisada, Takeshi T

Publication Date: 2022-11

Variant appearance in text: EGFR: 2239T>G; L747V

PubMed Link: 36193787

Variant Present in the following documents:

• Main text
• TCA-13-3225.pdf

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Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine

Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R

Publication Date: 2022-05

Variant appearance in text: EGFR: 2239T>G; Leu747Val

PubMed Link: 35244186

Variant Present in the following documents:

• Supplementary_Data2.xlsx, sheet 1
• Supplementary_Data3.xlsx, sheet 1

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A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses.

Cancers

Koopman, Bart B; Cajiao Garcia, Betzabel N BN; Kuijpers, Chantal C H J CCHJ; Damhuis, Ronald A M RAM; van der Wekken, Anthonie J AJ; Groen, Harry J M HJM; Schuuring, Ed E; Willems, Stefan M SM; van Kempen, Léon C LC

Publication Date: 2021-07-20

Variant appearance in text: EGFR: L747V

PubMed Link: 34298851

Variant Present in the following documents:

• Main text

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Mutation Spectrum of EGFR From 21,324 Chinese Patients With Non-Small Cell Lung Cancer (NSCLC) Successfully Tested by Multiple Methods in a CAP-Accredited Laboratory.

Pathology Oncology Research : Por

Mao, Linlin L; Zhao, Weiwei W; Li, Xiaoxia X; Zhang, Shangfei S; Zhou, Changhong C; Zhou, Danyan D; Ou, Xiaohua X; Xu, Yanyan Y; Tang, Yuanxiao Y; Ou, Xiaoyong X; Hu, Changming C; Ding, Xiangdong X; Luo, Pifu P; Yu, Shihui S

Publication Date: 2021

Variant appearance in text: EGFR: L747V

PubMed Link: 34257561

Variant Present in the following documents:

• Main text
• pore-27-602726.pdf

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Afatinib as first-line treatment in patients with EGFR-mutated non-small cell lung cancer in routine clinical practice.

Therapeutic Advances In Medical Oncology

Brückl, Wolfgang M WM; Reck, Martin M; Griesinger, Frank F; Schäfer, Harald H; Kortsik, Cornelius C; Gaska, Tobias T; Rawluk, Justyna J; Krüger, Stefan S; Kokowski, Konrad K; Budweiser, Stephan S; Ficker, Joachim H JH; Hoffmann, Christopher C; Schüler, Andrea A; Laack, Eckart E

Publication Date: 2021

Variant appearance in text: EGFR: L747V

PubMed Link: 33995597

Variant Present in the following documents:

• Main text
• 10.1177_17588359211012361.pdf

View BVdb publication page

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EGFR (p. G719A+L747V)/EML4-ALK Co-alterations in Lung Adenocarcinoma with Leptomeningeal Metastasis Responding to Afatinib Treatment: A Case Report.

Oncotargets And Therapy

Lu, Zhiqin Z; Wang, Xia X; Luo, Yuxi Y; Wei, Jianping J; Zeng, Zhimin Z; Xiong, Qiang Q; Cai, Jing J; Liu, Anwen A

Publication Date: 2021

Variant appearance in text: EGFR: L747V

PubMed Link: 33935502

Variant Present in the following documents:

• Main text

View BVdb publication page

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Non-invasive detection of EGFR and TP53 mutations through the combination of plasma, urine and sputum in advanced non-small cell lung cancer.

Oncology Letters

Wu, Zhen Z; Yang, Zhen Z; Li, Chun-Sun CS; Zhao, Wei W; Liang, Zhi-Xin ZX; Dai, Yu Y; Zeng, Jing J; Zhu, Qiang Q; Miao, Kai-Ling KL; Cui, Dong-Hua DH; Chen, Liang-An LA

Publication Date: 2019-10

Variant appearance in text: EGFR: L747V

PubMed Link: 31516572

Variant Present in the following documents:

• Supplementary_Data.pdf

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Afatinib in the first-line treatment of patients with non-small cell lung cancer: clinical evidence and experience.

Therapeutic Advances In Respiratory Disease

Ricciuti, Biagio B; Baglivo, Sara S; De Giglio, Andrea A; Chiari, Rita R

Publication Date: 2018

Variant appearance in text: EGFR: L747V

PubMed Link: 30355049

Variant Present in the following documents:

• Main text
• 10.1177_1753466618808659.pdf

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Comparison of uncommon EGFR exon 21 L858R compound mutations with single mutation.

Oncotargets And Therapy

Peng, Liang L; Song, Zhigang Z; Jiao, Shunchang S

Publication Date: 2015

Variant appearance in text: EGFR: L747V

PubMed Link: 25960661

Variant Present in the following documents:

• Main text
• ott-8-905.pdf

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Compound EGFR mutations and response to EGFR tyrosine kinase inhibitors.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer

Kobayashi, Susumu S; Canepa, Hannah M HM; Bailey, Alexandra S AS; Nakayama, Sohei S; Yamaguchi, Norihiro N; Goldstein, Michael A MA; Huberman, Mark S MS; Costa, Daniel B DB

Publication Date: 2013-01

Variant appearance in text: EGFR: L747V

PubMed Link: 23242437

Variant Present in the following documents:

• Main text

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