Publications:

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Overview on Therapeutic Options in Uncommon EGFR Mutant Non-Small Cell Lung Cancer (NSCLC): New Lights for an Unmet Medical Need.

International Journal Of Molecular Sciences

Pretelli, Giulia G; Spagnolo, Calogera Claudia CC; Ciappina, Giuliana G; Santarpia, Mariacarmela M; Pasello, Giulia G

Publication Date: 2023-05-17

Variant appearance in text: EGFR: L747S

PubMed Link: 37240224

Variant Present in the following documents:

• Main text
• ijms-24-08878.pdf

View BVdb publication page

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Evaluating the efficacy and cardiotoxicity of EGFR-TKI AC0010 with a novel multifunctional biosensor.

Microsystems & Nanoengineering

Jiang, Deming D; Wei, Xinwei X; Zhu, Yuxuan Y; Qiu, Yong Y; Liu, Xin X; Kong, Liubing L; Li, Fengheng F; Liu, Jingwen J; Zhuang, Liujing L; Wan, Hao H; Ying, Kejing K; Wang, Ping P

Publication Date: 2023

Variant appearance in text: EGFR: L747S

PubMed Link: 37180453

Variant Present in the following documents:

• Main text
• 41378_2023_Article_493.pdf

View BVdb publication page

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Performance of Ultra-Rapid Idylla™ EGFR Mutation Test in Non-Small-Cell Lung Cancer and Its Potential at Clinical Molecular Screening.

Cancers

Suda, Kenichi K; Sakai, Kazuko K; Ohira, Tatsuo T; Chikugo, Takaaki T; Satou, Takao T; Matsubayashi, Jun J; Nagao, Toshitaka T; Ikeda, Norihiko N; Tsutani, Yasuhiro Y; Mitsudomi, Tetsuya T; Nishio, Kazuto K

Publication Date: 2023-05-07

Variant appearance in text: EGFR: L747S

PubMed Link: 37174112

Variant Present in the following documents:

• cancers-15-02648.pdf

View BVdb publication page

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Monitoring EGFR-lung cancer evolution: a possible beginning of a "methylation era" in TKI resistance prediction.

Frontiers In Oncology

Fabrizio, Federico Pio FP; Sparaneo, Angelo A; Muscarella, Lucia Anna LA

Publication Date: 2023

Variant appearance in text: EGFR: L747S

PubMed Link: 37152062

Variant Present in the following documents:

• Main text
• fonc-13-1137384.pdf

View BVdb publication page

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Comprehensive analysis of prediction of the EGFR mutation and subtypes based on the spinal metastasis from primary lung adenocarcinoma.

Frontiers In Oncology

Cao, Ran R; Chen, Huanhuan H; Wang, Huan H; Wang, Yan Y; Cui, E-Nuo EN; Jiang, Wenyan W

Publication Date: 2023

Variant appearance in text: EGFR: L747S

PubMed Link: 37143947

Variant Present in the following documents:

• fonc-13-1154327.pdf

View BVdb publication page

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Toward the next generation EGFR inhibitors: an overview of osimertinib resistance mediated by EGFR mutations in non-small cell lung cancer.

Cell Communication And Signaling : Ccs

Li, Yufeng Y; Mao, Tianyu T; Wang, Jing J; Zheng, Hongrui H; Hu, Ziyi Z; Cao, Pingping P; Yang, Suisui S; Zhu, Lingyun L; Guo, Shunyao S; Zhao, Xinfei X; Tian, Yue Y; Shen, Hua H; Lin, Fan F

Publication Date: 2023-04-11

Variant appearance in text: EGFR: L747S

PubMed Link: 37041601

Variant Present in the following documents:

• Main text
• 12964_2023_Article_1082.pdf

View BVdb publication page

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[A Real-world Study on the Expression Characteristics of PD-L1 in Patients 
with Advanced EGFR Positive NSCLC and Its Relationship with the 
Therapeutic Efficacy of EGFR-TKIs].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Chen, Ran R; Gao, Xiang X; Xu, Fudong F; Zhang, Shucai S; Ma, Li L; Hu, Bo B

Publication Date: 2023-03-20

Variant appearance in text: EGFR: L747S

PubMed Link: 37035884

Variant Present in the following documents:

• zgfazz-26-3-217.pdf

View BVdb publication page

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T790M and Acquired Resistance of Epidermal Growth Factor Receptor to Tyrosine Kinase Inhibitors in Patients with Lung Adenocarcinoma.

Tanaffos

Mirtavoos-Mahyari, Hanifeh H; Abbasi Dezfouli, Azizollah A; Esfahani-Monfared, Zahra Z; Khosravi, Adnan A; Seifi, Sharareh S; Sheikhy, Kambiz K

Publication Date: 2022-03

Variant appearance in text: EGFR: L747S

PubMed Link: 37025321

Variant Present in the following documents:

• Main text
• Tanaffos-21-376.pdf

View BVdb publication page

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Genomic Landscape of Primary Resistance to Osimertinib Among Hispanic Patients with EGFR-Mutant Non-Small Cell Lung Cancer (NSCLC): Results of an Observational Longitudinal Cohort Study.

Targeted Oncology

Chamorro, Diego F DF; Cardona, Andrés F AF; Rodríguez, July J; Ruiz-Patiño, Alejandro A; Arrieta, Oscar O; Moreno-Pérez, Darwin A DA; Rojas, Leonardo L; Zatarain-Barrón, Zyanya Lucia ZL; Ardila, Dora V DV; Viola, Lucia L; Recondo, Gonzalo G; Blaquier, Juan B JB; Martín, Claudio C; Raez, Luis L; Samtani, Suraj S; Ordóñez-Reyes, Camila C; Garcia-Robledo, Juan Esteban JE; Corrales, Luis L; Sotelo, Carolina C; Ricaurte, Luisa L; Cuello, Mauricio M; Mejía, Sergio S; Jaller, Elvira E; Vargas, Carlos C; Carranza, Hernán H; Otero, Jorge J; Archila, Pilar P; Bermudez, Maritza M; Gamez, Tatiana T; Russo, Alessandro A; Malapelle, Umberto U; de Miguel Perez, Diego D; de Lima, Vladmir C Cordeiro VCC; Freitas, Helano H; Saldahna, Erick E; Rolfo, Christian C; Rosell, Rafael R; ,

Publication Date: 2023-04-05

Variant appearance in text: EGFR: L747S

PubMed Link: 37017806

Variant Present in the following documents:

• Main text
• 11523_2023_Article_955.pdf

View BVdb publication page

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Trends in Survival Rates of Non-Small Cell Lung Cancer With Use of Molecular Testing and Targeted Therapy in Korea, 2010-2020.

Jama Network Open

Chi, Sang Ah SA; Yu, Hyeyeon H; Choi, Yoon-La YL; Park, Sehhoon S; Sun, Jong-Mu JM; Lee, Se-Hoon SH; Ahn, Jin Seok JS; Ahn, Myung-Ju MJ; Choi, Dae-Ho DH; Kim, Kyunga K; Jung, Hyun Ae HA; Park, Keunchil K

Publication Date: 2023-03-01

Variant appearance in text: EGFR: L747S

PubMed Link: 36929402

Variant Present in the following documents:

• Main text

View BVdb publication page

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Development and validation of a mutation-based model to predict immunotherapeutic efficacy in NSCLC.

Frontiers In Oncology

He, Ping P; Liu, Jie J; Xu, Qingyuan Q; Ma, Huaijun H; Niu, Beifang B; Huang, Gang G; Wu, Wei W

Publication Date: 2023

Variant appearance in text: EGFR: 2240T>C; L747S; rs397517097

PubMed Link: 36910641

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 8

View BVdb publication page

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Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications

Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G

Publication Date: 2023-03-11

Variant appearance in text: EGFR: 2240T>C; Leu747Ser

PubMed Link: 36906579

Variant Present in the following documents:

• 41467_2023_36922_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Nanotechnology - a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer.

Beilstein Journal Of Nanotechnology

Gorachinov, Filip F; Mraiche, Fatima F; Moustafa, Diala Alhaj DA; Hishari, Ola O; Ismail, Yomna Y; Joseph, Jensa J; Crcarevska, Maja Simonoska MS; Dodov, Marija Glavas MG; Geskovski, Nikola N; Goracinova, Katerina K

Publication Date: 2023

Variant appearance in text: EGFR: L747S

PubMed Link: 36865093

Variant Present in the following documents:

• Beilstein_J_Nanotechnol-14-240.pdf

View BVdb publication page

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Durable response to osimertinib in an advanced lung adenocarcinoma patient with an uncommon EGFR T854A mutation: A case report.

Medicine

Zhao, Nan N; Xin, Hua H; Qin, Changjuan C; Li, Zhiqi Z; Sun, Hongbin H

Publication Date: 2022-12-09

Variant appearance in text: EGFR: L747S

PubMed Link: 36626541

Variant Present in the following documents:

• medi-101-e31875.pdf

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: EGFR: L747S

PubMed Link: 36561320

Variant Present in the following documents:

• Table3.xlsx, sheet 1
• Table2.xlsx, sheet 4

View BVdb publication page

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: EGFR: 2240T>C; L747S

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 3
• Table_2.xlsx, sheet 2

View BVdb publication page

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Non-Small Cell Lung Cancer Targeted Therapy: Drugs and Mechanisms of Drug Resistance.

International Journal Of Molecular Sciences

Wu, Jiajia J; Lin, Zhenghong Z

Publication Date: 2022-12-01

Variant appearance in text: EGFR: L747S

PubMed Link: 36499382

Variant Present in the following documents:

• Main text
• ijms-23-15056.pdf

View BVdb publication page

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Inconsistent clinical outcomes following afatinib treatment in NSCLC patients harboring uncommon epidermal growth factor receptor mutation.

Frontiers In Oncology

Dong, Wei W; Wang, Congjie C; Wang, Chunsheng C; Zhao, Kewei K; Ma, Zhao Z; Hu, Shanliang S

Publication Date: 2022

Variant appearance in text: EGFR: L747S

PubMed Link: 36425553

Variant Present in the following documents:

• DataSheet_1.pdf

View BVdb publication page

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Clinical characteristics and prognostic factors of pulmonary sarcomatoid carcinoma.

Journal Of Thoracic Disease

Zhao, Chenguang C; Gao, Shugeng S; Xue, Qi Q; Tan, Fengwei F; Gao, Yushun Y; Mao, Yousheng Y; Wang, Dali D; Zhao, Jun J; Yang, Ding D; Hong, Qian Q; Mu, Juwei J

Publication Date: 2022-10

Variant appearance in text: EGFR: L747S

PubMed Link: 36389311

Variant Present in the following documents:

• jtd-14-10-3773.pdf

View BVdb publication page

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Multiple mutations in the EGFR gene in lung cancer: a systematic review.

Translational Lung Cancer Research

Castañeda-González, Juan Pablo JP; Chaves, Juan José JJ; Parra-Medina, Rafael R

Publication Date: 2022-10

Variant appearance in text: EGFR: L747S

PubMed Link: 36386461

Variant Present in the following documents:

• Main text
• tlcr-11-10-2148.pdf

View BVdb publication page

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Predictive mutation signature of immunotherapy benefits in NSCLC based on machine learning algorithms.

Frontiers In Immunology

Liu, Zhichao Z; Lin, Guo G; Yan, Zeping Z; Li, Linduo L; Wu, Xingchen X; Shi, Jingrong J; He, Jianxing J; Zhao, Lei L; Liang, Hengrui H; Wang, Wei W

Publication Date: 2022

Variant appearance in text: EGFR: 2240T>C; L747S

PubMed Link: 36238300

Variant Present in the following documents:

• Table_1.xlsx, sheet 4

View BVdb publication page

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Durable response to afatinib rechallenge in a long-term survivor of non-small cell lung cancer harboring EGFR L858R and L747V mutations.

Thoracic Cancer

Kanbe, Mio M; Sunaga, Noriaki N; Hara, Kenichiro K; Sawada, Hiiru H; Wakamatsu, Ikuo I; Hara, Kentaro K; Muto, Sohei S; Sawada, Yuri Y; Masubuchi, Hiroaki H; Sato, Mari M; Miura, Yosuke Y; Tsurumaki, Hiroaki H; Yatomi, Masakiyo M; Sakurai, Reiko R; Koga, Yasuhiko Y; Ohtaki, Yoichi Y; Nagashima, Toshiteru T; Okano, Naoko N; Kubo, Nobuteru N; Maeno, Toshitaka T; Hisada, Takeshi T

Publication Date: 2022-11

Variant appearance in text: EGFR: L747S

PubMed Link: 36193787

Variant Present in the following documents:

• Main text
• TCA-13-3225.pdf

View BVdb publication page

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EPHA5 mutation was associated with adverse outcome of atezolizumab treatment in late-stage non-small cell lung cancers.

Bmc Pulmonary Medicine

Li, Zhenxiang Z; Zhou, Qing Q; Wang, Qi Q; Wang, Haiyong H; Yue, Weiming W

Publication Date: 2022-09-19

Variant appearance in text: EGFR: 2240T>C; L747S

PubMed Link: 36123678

Variant Present in the following documents:

• 12890_2022_2161_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: EGFR: 2240T>C; L747S

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Mucoepidermoid carcinoma (MEC) and adenosquamous carcinoma (ASC), the same or different entities?

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc

White, Valerie A VA; Hyrcza, Martin D MD; Lennerz, Jochen K JK; Thierauf, Julia J; Lokuhetty, Dilani D; Cree, Ian A IA; Indave, Blanca Iciar BI

Publication Date: 2022-10

Variant appearance in text: EGFR: L747S

PubMed Link: 35871081

Variant Present in the following documents:

• 41379_2022_1100_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Allele-specific activation, enzyme kinetics, and inhibitor sensitivities of EGFR exon 19 deletion mutations in lung cancer.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Brown, Benjamin P BP; Zhang, Yun-Kai YK; Kim, Soyeon S; Finneran, Patrick P; Yan, Yingjun Y; Du, Zhenfang Z; Kim, Jiyoon J; Hartzler, Abigail Leigh AL; LeNoue-Newton, Michele L ML; Smith, Adam W AW; Meiler, Jens J; Lovly, Christine M CM

Publication Date: 2022-07-26

Variant appearance in text: EGFR: L747S

PubMed Link: 35867821

Variant Present in the following documents:

• pnas.202206588.pdf

View BVdb publication page

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Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology

Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J

Publication Date: 2022

Variant appearance in text: EGFR: 2240T>C; L747S

PubMed Link: 35814426

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 2

View BVdb publication page

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Uncommon EGFR mutations in lung carcinoma: features and treatment outcomes in a retrospective French cohort.

Journal Of Thoracic Disease

Tankere, Pierre P; Boidot, Romain R; Bonniaud, Philippe P; Zouak, Ayoube A; Foucher, Pascal P; Milliere, Alice A; Bertaut, Aurélie A; Favier, Laure L; Lagrange, Aurélie A; Ghiringhelli, François F; Kaderbhai, Courèche Guillaume CG; Fraisse, Cléa C

Publication Date: 2022-06

Variant appearance in text: EGFR: L747S

PubMed Link: 35813741

Variant Present in the following documents:

• jtd-14-06-2034.pdf

View BVdb publication page

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Genomic profiling reveals non-small cell lung cancer with common mutations of EGFR exon 20 and exon 21: a case report.

Translational Cancer Research

Bi, Xiaojun X; Song, Pengyu P; Wang, Chengye C; Zhang, Xuefei X; Liu, Changhong C

Publication Date: 2022-05

Variant appearance in text: EGFR: L747S

PubMed Link: 35706785

Variant Present in the following documents:

• Main text
• tcr-11-05-1423.pdf

View BVdb publication page

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: EGFR: 2240T>C; L747S

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

View BVdb publication page

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Unique characteristics of G719X and S768I compound double mutations of epidermal growth factor receptor (EGFR) gene in lung cancer of coal-producing areas of East Yunnan in Southwestern China.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society

Wang, Jun-Ling JL; Fu, Yu-Dong YD; Gao, Yan-Hong YH; Li, Xiu-Ping XP; Xiong, Qian Q; Li, Rui R; Hou, Bo B; Huang, Ruo-Shan RS; Wang, Jun-Feng JF; Zhang, Jian-Kun JK; Lv, Jia-Ling JL; Zhang, Chao C; Li, Hong-Wei HW

Publication Date: 2022-05-23

Variant appearance in text: EGFR: L747S

PubMed Link: 35606799

Variant Present in the following documents:

• 41021_2022_248_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Molecular landscape and therapeutic alterations in Asian soft-tissue sarcoma patients.

Cancer Medicine

Gan, Meifu M; Zhang, Chen C; Qiu, Liqing L; Wang, Yue Y; Bao, Hua H; Yu, Ruoying R; Liu, Rui R; Wu, Xue X; Shao, Yang Y; Hou, Peifeng P; Fei, Zhenglei Z

Publication Date: 2022-11

Variant appearance in text: EGFR: 2240T>C; L747S

PubMed Link: 35586877

Variant Present in the following documents:

• CAM4-11-4070-s004.xlsx, sheet 1

View BVdb publication page

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TP53 Loss of Heterozygosity Induces De Novo SCLC Formation in EGFR-Mutated Lung Adenocarcinoma: A Case Report.

Jto Clinical And Research Reports

Kunimasa, Kei K; Hirotsu, Yosuke Y; Amemiya, Kenji K; Nakamura, Harumi H; Nishino, Kazumi K; Honma, Keiichiro K; Okami, Jiro J; Omata, Masao M; Kumagai, Toru T

Publication Date: 2022-05

Variant appearance in text: rs397517097

PubMed Link: 35498386

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

View BVdb publication page

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Osimertinib-Centered Therapy Against Uncommon Epidermal Growth Factor Receptor-Mutated Non-Small-Cell Lung Cancer- A Mini Review.

Frontiers In Oncology

Song, Chengyang C; Yang, Xueying X

Publication Date: 2022

Variant appearance in text: EGFR: L747S

PubMed Link: 35494059

Variant Present in the following documents:

• Main text
• fonc-12-834585.pdf

View BVdb publication page

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[Targeted Therapy and Mechanism of Drug Resistance in Non-small Cell Lung Cancer 
with Epidermal Growth Factor Receptor Gene Mutation].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Huang, Junxia J; Wang, Hong H

Publication Date: 2022-03-20

Variant appearance in text: EGFR: L747S

PubMed Link: 35340161

Variant Present in the following documents:

• Main text
• zgfazz-25-3-183.pdf

View BVdb publication page

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Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L

Publication Date: 2022-03-10

Variant appearance in text: EGFR: 2240T>C; L747S

PubMed Link: 35273153

Variant Present in the following documents:

• 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research

Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL

Publication Date: 2022-05

Variant appearance in text: EGFR: L747S

PubMed Link: 35229492

Variant Present in the following documents:

• PCMR-35-369-s003.xlsx, sheet 12

View BVdb publication page

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The Lifted Veil of Uncommon EGFR Mutation p.L747P in Non-Small Cell Lung Cancer: Molecular Feature and Targeting Sensitivity to Tyrosine Kinase Inhibitors.

Frontiers In Oncology

Yang, Guangjian G; Liu, Chengming C; Hu, Jiaqi J; Sun, Yang Y; Hu, Peizeng P; Liu, Liu L; Xu, Haiyan H; Li, Dazhou D; Li, Weihua W; Yang, Yaning Y; Sun, Nan N; He, Jie J; Wang, Yan Y

Publication Date: 2022

Variant appearance in text: EGFR: L747S

PubMed Link: 35223527

Variant Present in the following documents:

• Main text
• fonc-12-843299.pdf

View BVdb publication page

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: EGFR: Leu747Ser

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Osimertinib in advanced EGFR-mutant lung adenocarcinoma with asymptomatic brain metastases: an open-label, 3-arm, phase II pilot study.

Neuro-Oncology Advances

Peled, Nir N; Kian, Waleed W; Inbar, Edna E; Goldstein, Iris M IM; Zemel, Melanie M; Rotem, Ofer O; Rozenblum, Anna B AB; Nechushtan, Hovav H; Dudnik, Elizabeth E; Levin, Daniel D; Zer, Alona A; Keren-Rosenberg, Shoshana S; Yust-Katz, Shlomit S; Fuchs, Vered V; Remilah, Areen A AA; Shelef, Ilan I; Roisman, Laila C LC

Publication Date: 2022

Variant appearance in text: EGFR: L747S

PubMed Link: 35156036

Variant Present in the following documents:

• vdab188.pdf

View BVdb publication page

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Investigation of PALB2 Mutation and Correlation With Immunotherapy Biomarker in Chinese Non-Small Cell Lung Cancer Patients.

Frontiers In Oncology

Zhang, Jiexia J; Tang, Shuangfeng S; Zhang, Chunning C; Li, Mingyao M; Zheng, Yating Y; Hu, Xue X; Huang, Mengli M; Cheng, Xiangyang X

Publication Date: 2021

Variant appearance in text: EGFR: 2240T>C; L747S

PubMed Link: 35087742

Variant Present in the following documents:

• Table_2.xlsx, sheet 1

View BVdb publication page

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Therapeutic advances in non-small cell lung cancer: Focus on clinical development of targeted therapy and immunotherapy.

Medcomm

Cheng, Yuan Y; Zhang, Tao T; Xu, Qing Q

Publication Date: 2021-12

Variant appearance in text: EGFR: L747S

PubMed Link: 34977873

Variant Present in the following documents:

• Main text
• MCO2-2-692.pdf

View BVdb publication page

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MicroSEC filters sequence errors for formalin-fixed and paraffin-embedded samples.

Communications Biology

Ikegami, Masachika M; Kohsaka, Shinji S; Hirose, Takeshi T; Ueno, Toshihide T; Inoue, Satoshi S; Kanomata, Naoki N; Yamauchi, Hideko H; Mori, Taisuke T; Sekine, Shigeki S; Inamoto, Yoshihiro Y; Yatabe, Yasushi Y; Kobayashi, Hiroshi H; Tanaka, Sakae S; Mano, Hiroyuki H

Publication Date: 2021-12-15

Variant appearance in text: EGFR: 2240T>C; Leu747Ser

PubMed Link: 34912045

Variant Present in the following documents:

• 42003_2021_2930_MOESM4_ESM.xlsx, sheet 2

View BVdb publication page

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MicroSEC filters sequence errors for formalin-fixed and paraffin-embedded samples.

Communications Biology

Ikegami, Masachika M; Kohsaka, Shinji S; Hirose, Takeshi T; Ueno, Toshihide T; Inoue, Satoshi S; Kanomata, Naoki N; Yamauchi, Hideko H; Mori, Taisuke T; Sekine, Shigeki S; Inamoto, Yoshihiro Y; Yatabe, Yasushi Y; Kobayashi, Hiroshi H; Tanaka, Sakae S; Mano, Hiroyuki H

Publication Date: 2021-12-15

Variant appearance in text: EGFR: 2240T>C; Leu747Ser

PubMed Link: 34912045

Variant Present in the following documents:

• 42003_2021_2930_MOESM4_ESM.xlsx, sheet 2

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Identification of Immune-Related Gene Signatures in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma.

Frontiers In Immunology

Li, Na N; Wang, Jiahong J; Zhan, Xianquan X

Publication Date: 2021

Variant appearance in text: EGFR: 2240T>C; L747P

PubMed Link: 34887858

Variant Present in the following documents:

• Table_3.xlsx, sheet 1

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Real-World Approach for Molecular Analysis of Acquired EGFR Tyrosine Kinase Inhibitor Resistance Mechanisms in NSCLC.

Jto Clinical And Research Reports

Hondelink, Liesbeth M LM; Jebbink, Merel M; von der Thüsen, Jan H JH; Cohen, Danielle D; Dubbink, Hendrikus J HJ; Paats, Marthe S MS; Dingemans, Anne-Marie C AC; de Langen, Adrianus J AJ; Boelens, Mirjam C MC; Smit, Egbert F EF; Postmus, Pieter E PE; van Wezel, Tom T; Monkhorst, Kim K

Publication Date: 2021-12

Variant appearance in text: EGFR: L747S

PubMed Link: 34849493

Variant Present in the following documents:

• Main text
• main.pdf

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Qing-Kai-Ling Injection Acts Better Than Shen-Fu Injection in Enhancing the Antitumor Effect of Gefitinib in Resistant Non-Small Cell Lung Cancer Models.

Evidence-Based Complementary And Alternative Medicine : Ecam

Yu, Ya-Ya YY; Zhu, Yan-Juan YJ; Zou, Ying Y; Xiao, Zhen-Zhen ZZ; Shi, Shuai S; Liu, Yi-Hong YH; Chang, Xue-Song XS; Chen, Ya-Dong YD; Zhang, Hai-Bo HB

Publication Date: 2021

Variant appearance in text: EGFR: L747S

PubMed Link: 34646330

Variant Present in the following documents:

• ECAM2021-9911935.pdf

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Molecular Mechanism of EGFR-TKI Resistance in EGFR-Mutated Non-Small Cell Lung Cancer: Application to Biological Diagnostic and Monitoring.

Cancers

Reita, Damien D; Pabst, Lucile L; Pencreach, Erwan E; Guérin, Eric E; Dano, Laurent L; Rimelen, Valérie V; Voegeli, Anne-Claire AC; Vallat, Laurent L; Mascaux, Céline C; Beau-Faller, Michèle M

Publication Date: 2021-09-30

Variant appearance in text: EGFR: L747S

PubMed Link: 34638411

Variant Present in the following documents:

• Main text

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: EGFR: L747S

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Leu747Ser

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

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Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine

Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z

Publication Date: 2021-10

Variant appearance in text: EGFR: Leu747Ser

PubMed Link: 34599863

Variant Present in the following documents:

• CAM4-10-7360-s002.xlsx, sheet 2

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High Incidence of C797S Mutation in Patients With Long Treatment History of EGFR Tyrosine Kinase Inhibitors Including Osimertinib.

Jto Clinical And Research Reports

Osoegawa, Atsushi A; Yamaguchi, Masafumi M; Nakamura, Tomomi T; Morinaga, Ryotaro R; Tanaka, Kentaro K; Kashiwabara, Kosuke K; Miura, Takashi T; Suetsugu, Takayuki T; Harada, Taishi T; Asoh, Tatsuma T; Taguchi, Kenichi K; Nabeshima, Kazuki K; Kishimoto, Junji J; Sakai, Kazuko K; Nishio, Kazuto K; Sugio, Kenji K

Publication Date: 2021-07

Variant appearance in text: rs397517097

PubMed Link: 34590037

Variant Present in the following documents:

• mmc2.xlsx, sheet 1
• mmc1.xlsx, sheet 1

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Afatinib treatment response in advanced lung adenocarcinomas harboring uncommon mutations.

Thoracic Cancer

Li, Teng T; Wang, Shouzheng S; Ying, Jianming J; Wang, Yan Y; Hu, Xingsheng X; Hao, Xuezhi X; Xu, Ziyi Z; Xing, Puyuan P; Li, Junling J

Publication Date: 2021-11

Variant appearance in text: EGFR: L747S

PubMed Link: 34549528

Variant Present in the following documents:

• Main text

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Afatinib treatment response in advanced lung adenocarcinomas harboring uncommon mutations.

Thoracic Cancer

Li, Teng T; Wang, Shouzheng S; Ying, Jianming J; Wang, Yan Y; Hu, Xingsheng X; Hao, Xuezhi X; Xu, Ziyi Z; Xing, Puyuan P; Li, Junling J

Publication Date: 2021-11

Variant appearance in text: EGFR: L747S

PubMed Link: 34549528

Variant Present in the following documents:

• Main text

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