Publications:

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Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.

Cancer Medicine

Liu, Binliang B; Yi, Zongbi Z; Guan, Yanfang Y; Ouyang, Quchang Q; Li, Chunxiao C; Guan, Xiuwen X; Lv, Dan D; Li, Lixi L; Zhai, Jingtong J; Qian, Haili H; Xu, Binghe B; Ma, Fei F; Zeng, Yixin Y

Publication Date: 2022-07

Variant appearance in text: EGFR: 2249C>A; A750E

PubMed Link: 35393784

Variant Present in the following documents:

• CAM4-11-2767-s001.xlsx, sheet 1

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Identification of Immune-Related Gene Signatures in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma.

Frontiers In Immunology

Li, Na N; Wang, Jiahong J; Zhan, Xianquan X

Publication Date: 2021

Variant appearance in text: EGFR: 2249C>A

PubMed Link: 34887858

Variant Present in the following documents:

• Table_3.xlsx, sheet 1

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Structure-based classification predicts drug response in EGFR-mutant NSCLC.

Nature

Robichaux, Jacqulyne P JP; Le, Xiuning X; Vijayan, R S K RSK; Hicks, J Kevin JK; Heeke, Simon S; Elamin, Yasir Y YY; Lin, Heather Y HY; Udagawa, Hibiki H; Skoulidis, Ferdinandos F; Tran, Hai H; Varghese, Susan S; He, Junqin J; Zhang, Fahao F; Nilsson, Monique B MB; Hu, Lemei L; Poteete, Alissa A; Rinsurongkawong, Waree W; Zhang, Xiaoshan X; Ren, Chenghui C; Liu, Xiaoke X; Hong, Lingzhi L; Zhang, Jianjun J; Diao, Lixia L; Madison, Russell R; Schrock, Alexa B AB; Saam, Jennifer J; Raymond, Victoria V; Fang, Bingliang B; Wang, Jing J; Ha, Min Jin MJ; Cross, Jason B JB; Gray, Jhanelle E JE; Heymach, John V JV

Publication Date: 2021-09

Variant appearance in text: EGFR: A750E

PubMed Link: 34526717

Variant Present in the following documents:

• 41586_2021_3898_MOESM1_ESM.pdf

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Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer.

Npj Breast Cancer

Yi, Zongbi Z; Rong, Guohua G; Guan, Yanfang Y; Li, Jin J; Chang, Lianpeng L; Li, Hui H; Liu, Binliang B; Wang, Wenna W; Guan, Xiuwen X; Ouyang, Quchang Q; Li, Lixi L; Zhai, Jingtong J; Li, Chunxiao C; Li, Lifeng L; Xia, Xuefeng X; Yang, Ling L; Qian, Haili H; Yi, Xin X; Xu, Binghe B; Ma, Fei F

Publication Date: 2020

Variant appearance in text: EGFR: 2249C>A; A750E

PubMed Link: 33145402

Variant Present in the following documents:

• 41523_2020_201_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Blood-Based Next-Generation Sequencing Analysis of Appendiceal Cancers.

The Oncologist

Shaib, Walid L WL; Zakka, Katerina K; Staley, Charles C; Roberts, Ali A; Akce, Mehmet M; Wu, Christina C; Alese, Olatunji B OB; El-Rayes, Bassel F BF

Publication Date: 2020-05

Variant appearance in text: EGFR: A750E

PubMed Link: 31784493

Variant Present in the following documents:

• Main text

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Competitive evolution of NSCLC tumor clones and the drug resistance mechanism of first-generation EGFR-TKIs in Chinese NSCLC patients.

Heliyon

Deng, Qinfang Q; Xie, Boxiong B; Wu, Leilei L; Ji, Xianxiu X; Li, Chao C; Feng, Li L; Fang, Qiyu Q; Bao, Yuchen Y; Li, Jialu J; Jin, Shengnan S; Ding, Chunming C; Li, Yixue Y; Zhou, Songwen S

Publication Date: 2018-12

Variant appearance in text: EGFR: A750E

PubMed Link: 30603682

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

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Organotypic three-dimensional cancer cell cultures mirror drug responses in vivo: lessons learned from the inhibition of EGFR signaling.

Oncotarget

Jacobi, Nico N; Seeboeck, Rita R; Hofmann, Elisabeth E; Schweiger, Helmut H; Smolinska, Veronika V; Mohr, Thomas T; Boyer, Alexandra A; Sommergruber, Wolfgang W; Lechner, Peter P; Pichler-Huebschmann, Corina C; Önder, Kamil K; Hundsberger, Harald H; Wiesner, Christoph C; Eger, Andreas A

Publication Date: 2017-12-08

Variant appearance in text: EGFR: A750E

PubMed Link: 29296175

Variant Present in the following documents:

• Main text
• oncotarget-08-107423.pdf

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Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients.

Neoplasia (New York, N.Y.)

Xiao, Zhiguang Z; Gaertner, Silvia S; Morresi-Hauf, Alicia A; Genzel, Rebecca R; Duell, Thomas T; Ullrich, Axel A; Knyazev, Pjotr G PG

Publication Date: 2017-05

Variant appearance in text: EGFR: A750E

PubMed Link: 28391030

Variant Present in the following documents:

• Main text
• main.pdf

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Discrepancies in cancer genomic sequencing highlight opportunities for driver mutation discovery.

Cancer Research

Hudson, Andrew M AM; Yates, Tim T; Li, Yaoyong Y; Trotter, Eleanor W EW; Fawdar, Shameem S; Chapman, Phil P; Lorigan, Paul P; Biankin, Andrew A; Miller, Crispin J CJ; Brognard, John J

Publication Date: 2014-11-15

Variant appearance in text: EGFR: A750E

PubMed Link: 25256751

Variant Present in the following documents:

• Main text

View BVdb publication page

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