EGFR c.2254_2255delinsAT ;(p.S752I)

Variant ID: 7-55242484-TC-AT

NM_005228.3(EGFR):c.2254_2255delinsAT;(p.S752I)

This variant was identified in 18 publications

View GRCh38 version.




Publications:


Protein co-expression network-based profiles revealed from laser-microdissected cancerous cells of lung squamous-cell carcinomas.

Scientific Reports
Nishimura, Toshihide T; Fujii, Kiyonaga K; Nakamura, Haruhiko H; Naruki, Saeko S; Sakai, Hiroki H; Kimura, Hiroyuki H; Miyazawa, Tomoyuki T; Takagi, Masayuki M; Furuya, Naoki N; Marko-Varga, Gyorgy G; Kato, Harubumi H; Saji, Hisashi H
Publication Date: 2021-10-12

Variant appearance in text: EGFR: S752I
PubMed Link: 34642392
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_99695.pdf
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Upfront admixing antibodies and EGFR inhibitors preempts sequential treatments in lung cancer models.

Embo Molecular Medicine
Marrocco, Ilaria I; Romaniello, Donatella D; Vaknin, Itay I; Drago-Garcia, Diana D; Oren, Roni R; Uribe, Mary Luz ML; Belugali Nataraj, Nishanth N; Ghosh, Soma S; Eilam, Raya R; Salame, Tomer-Meir TM; Lindzen, Moshit M; Yarden, Yosef Y
Publication Date: 2021-04-09

Variant appearance in text: EGFR: S752I
PubMed Link: 33660397
Variant Present in the following documents:
  • EMMM-13-e13144-s007.pdf
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Promoter Methylation of Selected Genes in Non-Small-Cell Lung Cancer Patients and Cell Lines.

International Journal Of Molecular Sciences
Sarne, Victoria V; Huter, Samuel S; Braunmueller, Sandrina S; Rakob, Lisa L; Jacobi, Nico N; Kitzwögerer, Melitta M; Wiesner, Christoph C; Obrist, Peter P; Seeboeck, Rita R
Publication Date: 2020-06-28

Variant appearance in text: EGFR: S752I
PubMed Link: 32605217
Variant Present in the following documents:
  • Main text
  • ijms-21-04595.pdf
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Expression of C-terminal ALK, RET, or ROS1 in lung cancer cells with or without fusion.

Bmc Cancer
Furugaki, Koh K; Mochizuki, Marie M; Kohno, Mirei M; Shu, Sei S; Harada, Naoki N; Yoshimura, Yasushi Y
Publication Date: 2019-04-03

Variant appearance in text: EGFR: S752I
PubMed Link: 30943926
Variant Present in the following documents:
  • Main text
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Oncogene mutational analysis in Chinese gastrointestinal stromal tumor patients.

Oncotargets And Therapy
Chen, Qiong Q; Li, Rong R; Zhang, Zhi-Gao ZG; Deng, Qiao-Ting QT; Li, Kun K; Wang, Hao H; Yang, Xue-Xi XX; Wu, Ying-Song YS
Publication Date: 2018

Variant appearance in text: EGFR: S752I
PubMed Link: 29719410
Variant Present in the following documents:
  • Main text
  • ott-11-2279.pdf
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Organotypic three-dimensional cancer cell cultures mirror drug responses in vivo: lessons learned from the inhibition of EGFR signaling.

Oncotarget
Jacobi, Nico N; Seeboeck, Rita R; Hofmann, Elisabeth E; Schweiger, Helmut H; Smolinska, Veronika V; Mohr, Thomas T; Boyer, Alexandra A; Sommergruber, Wolfgang W; Lechner, Peter P; Pichler-Huebschmann, Corina C; Önder, Kamil K; Hundsberger, Harald H; Wiesner, Christoph C; Eger, Andreas A
Publication Date: 2017-12-08

Variant appearance in text: EGFR: S752I
PubMed Link: 29296175
Variant Present in the following documents:
  • Main text
  • oncotarget-08-107423.pdf
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The RAS-related GTPase RHOB confers resistance to EGFR-tyrosine kinase inhibitors in non-small-cell lung cancer via an AKT-dependent mechanism.

Embo Molecular Medicine
Calvayrac, Olivier O; Mazières, Julien J; Figarol, Sarah S; Marty-Detraves, Claire C; Raymond-Letron, Isabelle I; Bousquet, Emilie E; Farella, Magali M; Clermont-Taranchon, Estelle E; Milia, Julie J; Rouquette, Isabelle I; Guibert, Nicolas N; Lusque, Amélie A; Cadranel, Jacques J; Mathiot, Nathalie N; Savina, Ariel A; Pradines, Anne A; Favre, Gilles G
Publication Date: 2017-02

Variant appearance in text: EGFR: S752I
PubMed Link: 28003335
Variant Present in the following documents:
  • Main text
  • EMMM-9-238.pdf
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EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 function.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Phuchareon, Janyaporn J; McCormick, Frank F; Eisele, David W DW; Tetsu, Osamu O
Publication Date: 2015-07-21

Variant appearance in text: EGFR: S752I
PubMed Link: 26150526
Variant Present in the following documents:
  • Main text
View BVdb publication page



Single-Tube Mutation Scanning of The Epidermal Growth Factor Receptor Gene Using Multiplex LATE-PCR and Lights-On/Lights-Off Probes.

Journal Of Molecular Biomarkers & Diagnosis
Tetrault, Shana M SM; Rice, John E JE; Wangh, Lawrence J LJ; Sanchez, J Aquiles JA
Publication Date: 2014-05-01

Variant appearance in text: EGFR: S752I
PubMed Link: 25411647
Variant Present in the following documents:
  • Main text
View BVdb publication page



Tongue carcinoma infrequently harbor common actionable genetic alterations.

Bmc Cancer
Tan, Daniel S W DS; Wang, Weining W; Leong, Hui Sun HS; Sew, Pui Hoon PH; Lau, Dawn P DP; Chong, Fui Teen FT; Krisna, Sai Sakktee SS; Lim, Tony K H TK; Iyer, N Gopalakrishna NG
Publication Date: 2014-09-19

Variant appearance in text: EGFR: S752I
PubMed Link: 25234657
Variant Present in the following documents:
  • Main text
View BVdb publication page



Absence of 19 known hotspot oncogenic mutations in soft tissue clear cell sarcoma: two cases report with review of the literature.

International Journal Of Clinical And Experimental Pathology
Liu, Chunxia C; Ren, Yan Y; Li, Xiaoying X; Cao, Yuwen Y; Chen, Yunzhao Y; Cui, Xiaobin X; Li, Li L; Li, Feng F
Publication Date: 2014

Variant appearance in text: EGFR: S752I
PubMed Link: 25197404
Variant Present in the following documents:
  • Main text
View BVdb publication page



Validation and utilisation of high-coverage next-generation sequencing to deliver the pharmacological audit trail.

British Journal Of Cancer
Ong, M M; Carreira, S S; Goodall, J J; Mateo, J J; Figueiredo, I I; Rodrigues, D N DN; Perkins, G G; Seed, G G; Yap, T A TA; Attard, G G; de Bono, J S JS
Publication Date: 2014-08-26

Variant appearance in text: EGFR: S752I
PubMed Link: 24983367
Variant Present in the following documents:
View BVdb publication page



Oncogene mutational profile in nasopharyngeal carcinoma.

Oncotargets And Therapy
Zhang, Zi-Chen ZC; Fu, Sha S; Wang, Fang F; Wang, Hai-Yun HY; Zeng, Yi-Xin YX; Shao, Jian-Yong JY
Publication Date: 2014

Variant appearance in text: EGFR: S752I
PubMed Link: 24672248
Variant Present in the following documents:
  • Main text
  • ott-7-457.pdf
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Genotyping and genomic profiling of non-small-cell lung cancer: implications for current and future therapies.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology
Li, Tianhong T; Kung, Hsing-Jien HJ; Mack, Philip C PC; Gandara, David R DR
Publication Date: 2013-03-10

Variant appearance in text: EGFR: S752I
PubMed Link: 23401433
Variant Present in the following documents:
  • Main text
View BVdb publication page



Oncogene Mutation Survey in MPNST Cell Lines Enhances the Dominant Role of Hyperactive Ras in NF1 Associated Pro-Survival and Malignancy.

Translational Oncogenomics
Sun, Daochun D; Tainsky, Michael A MA; Haddad, Ramsi R
Publication Date: 2012

Variant appearance in text: EGFR: S752I
PubMed Link: 22346343
Variant Present in the following documents:
  • Main text
View BVdb publication page



Fresh surgical specimens yield breast stem/progenitor cells and reveal their oncogenic abnormalities.

Annals Of Surgical Oncology
Pommier, Suellen J SJ; Hernandez, Ariel A; Han, Esther E; Massimino, Kristen K; Muller, Patrick P; Diggs, Brian B; Chamberlain, Erin E; Murphy, Jennifer J; Hansen, Juliana J; Naik, Arpana A; Vetto, John J; Pommier, Rodney F RF
Publication Date: 2012-02

Variant appearance in text: EGFR: S752I
PubMed Link: 21748247
Variant Present in the following documents:
  • 10434_2011_1892_MOESM2_ESM.pdf
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Establishment and characterization of primary lung cancer cell lines from Chinese population.

Acta Pharmacologica Sinica
Zheng, Chao C; Sun, Yi-hua YH; Ye, Xiao-lei XL; Chen, Hai-quan HQ; Ji, Hong-bin HB
Publication Date: 2011-03

Variant appearance in text: EGFR: S752I
PubMed Link: 21372829
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients.

British Journal Of Cancer
Koivunen, J P JP; Kim, J J; Lee, J J; Rogers, A M AM; Park, J O JO; Zhao, X X; Naoki, K K; Okamoto, I I; Nakagawa, K K; Yeap, B Y BY; Meyerson, M M; Wong, K-K KK; Richards, W G WG; Sugarbaker, D J DJ; Johnson, B E BE; Jänne, P A PA
Publication Date: 2008-07-22

Variant appearance in text: EGFR: S752I
PubMed Link: 18594528
Variant Present in the following documents:
  • Main text
  • 6604469a.pdf
View BVdb publication page