EGFR c.2257_2259delinsGTAAGC ;(p.P753delinsVS)

Variant ID: 7-55242487-CCG-GTAAGC

NM_005228.3(EGFR):c.2257_2259delinsGTAAGC;(p.P753delinsVS)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Analysis of acquired resistance mechanisms to osimertinib in patients with EGFR-mutated advanced non-small cell lung cancer from the AURA3 trial.

Nature Communications
Chmielecki, Juliann J; Mok, Tony T; Wu, Yi-Long YL; Han, Ji-Youn JY; Ahn, Myung-Ju MJ; Ramalingam, Suresh S SS; John, Thomas T; Okamoto, Isamu I; Yang, James Chih-Hsin JC; Shepherd, Frances A FA; Bulusu, Krishna C KC; Laus, Gianluca G; Collins, Barbara B; Barrett, J Carl JC; Hartmaier, Ryan J RJ; Papadimitrakopoulou, Vassiliki V
Publication Date: 2023-02-27

Variant appearance in text: EGFR: P753delinsVS
PubMed Link: 36849516
Variant Present in the following documents:
  • 41467_2023_35962_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



A multicenter-retrospective study of non-small-cell lung carcinoma harboring uncommon epidermal growth factor receptor (EGFR) mutations: different subtypes of EGFR exon 19 deletion-insertions exhibit the clinical characteristics and prognosis of non-small cell lung carcinoma.

Translational Lung Cancer Research
Chen, Ying Y; Xu, Jinhe J; Zhang, Lei L; Song, Yingfang Y; Wen, Wen W; Lu, Jun J; Zhao, Zhongquan Z; Kong, Wencui W; Liu, Wei W; Guo, Aiping A; Santarpia, Mariacarmela M; Yamada, Tadaaki T; Cai, Xiuyu X; Yu, Zongyang Z
Publication Date: 2022-02

Variant appearance in text: EGFR: P753delinsVS
PubMed Link: 35280318
Variant Present in the following documents:
  • Main text
  • tlcr-11-02-238.pdf
View BVdb publication page



A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses.

Cancers
Koopman, Bart B; Cajiao Garcia, Betzabel N BN; Kuijpers, Chantal C H J CCHJ; Damhuis, Ronald A M RAM; van der Wekken, Anthonie J AJ; Groen, Harry J M HJM; Schuuring, Ed E; Willems, Stefan M SM; van Kempen, Léon C LC
Publication Date: 2021-07-20

Variant appearance in text: EGFR: P753delinsVS
PubMed Link: 34298851
Variant Present in the following documents:
  • Main text
  • cancers-13-03641.pdf
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: EGFR: P753delinsVS
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Phase and context shape the function of composite oncogenic mutations.

Nature
Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS
Publication Date: 2020-06

Variant appearance in text: EGFR: P753delinsVS
PubMed Link: 32461694
Variant Present in the following documents:
  • NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx, sheet 2
View BVdb publication page



Influence of afatinib dose on outcomes of advanced EGFR-mutant NSCLC patients with brain metastases.

Bmc Cancer
Tan, Wan-Ling WL; Ng, Quan Sing QS; Lim, Cindy C; Tan, Eng Huat EH; Toh, Chee Keong CK; Ang, Mei-Kim MK; Kanesvaran, Ravindran R; Jain, Amit A; Tan, Daniel S W DSW; Lim, Darren Wan-Teck DW
Publication Date: 2018-12-03

Variant appearance in text: EGFR: P753delinsVS
PubMed Link: 30509246
Variant Present in the following documents:
  • Main text
  • 12885_2018_Article_5110.pdf
View BVdb publication page



StrandAdvantage test for early-line and advanced-stage treatment decisions in solid tumors.

Cancer Medicine
Sen, Manimala M; Katragadda, Shanmukh S; Ravichandran, Aarthi A; Deshpande, Gouri G; Parulekar, Minothi M; Nayanala, Swetha S; Vittal, Vikram V; Shen, Weiming W; Phooi Nee Yong, Melanie M; Jacob, Jemima J; Parchuru, Sravanthi S; Dhanuskodi, Kalpana K; Eyring, Kenneth K; Agrawal, Pooja P; Agarwal, Smita S; Shanmugam, Ashwini A; Gupta, Satish S; Vishwanath, Divya D; Kumari, Kiran K; Hariharan, Arun K AK; Balaji, Sai A SA; Liang, Qiaoling Q; Robolledo, Belen B; Gauribidanur Raghavendrachar, Vijayashree V; Oomer Farooque, Mohammed M; Buresh, Cary J CJ; Ramamoorthy, Preveen P; Bahadur, Urvashi U; Subramanian, Kalyanasundaram K; Hariharan, Ramesh R; Veeramachaneni, Vamsi V; Sankaran, Satish S; Gupta, Vaijayanti V
Publication Date: 2017-05

Variant appearance in text: EGFR: P753delinsVS
PubMed Link: 28371134
Variant Present in the following documents:
  • CAM4-6-883-s002.xlsx, sheet 4
View BVdb publication page