EGFR c.2260_2262del ;(p.K754del)

Variant ID: 7-55242490-GAAA-G

NM_005228.3(EGFR):c.2260_2262del;(p.K754del)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene
Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S
Publication Date: 2022-04

Variant appearance in text: EGFR: K754del
PubMed Link: 35304574
Variant Present in the following documents:
  • 41388_2022_Article_2263.pdf
View BVdb publication page



Structure-based classification predicts drug response in EGFR-mutant NSCLC.

Nature
Robichaux, Jacqulyne P JP; Le, Xiuning X; Vijayan, R S K RSK; Hicks, J Kevin JK; Heeke, Simon S; Elamin, Yasir Y YY; Lin, Heather Y HY; Udagawa, Hibiki H; Skoulidis, Ferdinandos F; Tran, Hai H; Varghese, Susan S; He, Junqin J; Zhang, Fahao F; Nilsson, Monique B MB; Hu, Lemei L; Poteete, Alissa A; Rinsurongkawong, Waree W; Zhang, Xiaoshan X; Ren, Chenghui C; Liu, Xiaoke X; Hong, Lingzhi L; Zhang, Jianjun J; Diao, Lixia L; Madison, Russell R; Schrock, Alexa B AB; Saam, Jennifer J; Raymond, Victoria V; Fang, Bingliang B; Wang, Jing J; Ha, Min Jin MJ; Cross, Jason B JB; Gray, Jhanelle E JE; Heymach, John V JV
Publication Date: 2021-09

Variant appearance in text: EGFR: K754del
PubMed Link: 34526717
Variant Present in the following documents:
  • Main text
  • 41586_2021_3898_MOESM1_ESM.pdf
  • 41586_2021_Article_3898.pdf
View BVdb publication page



EGFR mutation status in a series of Turkish non-small cell lung cancer patients.

Biomedical Reports
Calibasi-Kocal, Gizem G; Amirfallah, Arsalan A; Sever, Tolga T; Umit Unal, Olcun O; Gurel, Duygu D; Oztop, Ilhan I; Ellidokuz, Hulya H; Basbinar, Yasemin Y
Publication Date: 2020-08

Variant appearance in text: EGFR: Lys754del
PubMed Link: 32509305
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular Characteristics and Clinical Outcomes of EGFR Exon 19 C-Helix Deletion in Non-Small Cell Lung Cancer and Response to EGFR TKIs.

Translational Oncology
Xu, Chun-Wei CW; Lei, Lei L; Wang, Wen-Xian WX; Lin, Li L; Zhu, You-Cai YC; Wang, Hong H; Miao, Li-Yun LY; Wang, Li-Ping LP; Zhuang, Wu W; Fang, Mei-Yu MY; Lv, Tang-Feng TF; Song, Yong Y
Publication Date: 2020-09

Variant appearance in text: EGFR: K754del
PubMed Link: 32492620
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Molecular characteristics and clinical outcomes of EGFR exon 19 indel subtypes to EGFR TKIs in NSCLC patients.

Oncotarget
Su, Jian J; Zhong, Wenzhao W; Zhang, Xuchao X; Huang, Ying Y; Yan, Honghong H; Yang, Jinji J; Dong, Zhongyi Z; Xie, Zhi Z; Zhou, Qing Q; Huang, Xiaosui X; Lu, Danxia D; Yan, Wenqing W; Wu, Yi-Long YL
Publication Date: 2017-12-19

Variant appearance in text: EGFR: K754del
PubMed Link: 29340050
Variant Present in the following documents:
  • oncotarget-08-111246.pdf
View BVdb publication page



Assessment of EGFR mutation status in lung adenocarcinoma by immunohistochemistry using antibodies specific to the two major forms of mutant EGFR.

The Journal Of Molecular Diagnostics : Jmd
Brevet, Marie M; Arcila, Maria M; Ladanyi, Marc M
Publication Date: 2010-03

Variant appearance in text: EGFR: K754del
PubMed Link: 20093391
Variant Present in the following documents:
  • Main text
View BVdb publication page



Frequently increased epidermal growth factor receptor (EGFR) copy numbers and decreased BRCA1 mRNA expression in Japanese triple-negative breast cancers.

Bmc Cancer
Toyama, Tatsuya T; Yamashita, Hiroko H; Kondo, Naoto N; Okuda, Katsuhiro K; Takahashi, Satoru S; Sasaki, Hidefumi H; Sugiura, Hiroshi H; Iwase, Hirotaka H; Fujii, Yoshitaka Y
Publication Date: 2008-10-25

Variant appearance in text: EGFR: K754del
PubMed Link: 18950515
Variant Present in the following documents:
  • Main text
  • 1471-2407-8-309.pdf
View BVdb publication page