EGFR c.2264C>G ;(p.A755G)

Variant ID: 7-55242494-C-G

NM_005228.3(EGFR):c.2264C>G;(p.A755G)

This variant was identified in 12 publications

View GRCh38 version.




Publications:


An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology
Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y
Publication Date: 2022

Variant appearance in text: EGFR: 2264C>G; A755G
PubMed Link: 36505399
Variant Present in the following documents:
  • Table_2.xlsx, sheet 3
  • Table_2.xlsx, sheet 2
View BVdb publication page



Assessing and Evaluating the Scope and Constraints of Idylla Molecular Assays by Using Different Source Materials in Routine Diagnostic Settings.

International Journal Of Molecular Sciences
Boppudi, Sanga Mitra SM; Scheil-Bertram, Stefanie S; Faust, Elisabeth E; Annamneedi, Anil A; Fisseler-Eckhoff, Annette A
Publication Date: 2022-10-19

Variant appearance in text: EGFR: A755G
PubMed Link: 36293374
Variant Present in the following documents:
  • ijms-23-12515.pdf
View BVdb publication page



Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications
Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L
Publication Date: 2022-03-10

Variant appearance in text: EGFR: 2264C>G; A755G
PubMed Link: 35273153
Variant Present in the following documents:
  • 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Utilizing phenotypic characteristics of metastatic brain tumors to improve the probability of detecting circulating tumor DNA from cerebrospinal fluid in non-small-cell lung cancer patients: development and validation of a prediction model in a prospective cohort study.

Esmo Open
Li, M M; Hou, X X; Zheng, L L; Ma, Y Y; Li, D D; Lv, Y Y; Chen, J J; Zheng, W W; Shao, Y Y; Mou, Y Y; Chen, L L
Publication Date: 2022-02

Variant appearance in text: EGFR: A755G
PubMed Link: 34922300
Variant Present in the following documents:
  • mmc1.xlsx, sheet 1
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2264C>G; A755G
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



The effectiveness of afatinib in patients with lung adenocarcinoma harboring complex epidermal growth factor receptor mutation.

Therapeutic Advances In Medical Oncology
Wu, Shang-Gin SG; Yu, Chong-Jen CJ; Yang, James Chih-Hsin JC; Shih, Jin-Yuan JY
Publication Date: 2020

Variant appearance in text: EGFR: A755G
PubMed Link: 32843903
Variant Present in the following documents:
  • Main text
  • 10.1177_1758835920946156.pdf
View BVdb publication page



Phase and context shape the function of composite oncogenic mutations.

Nature
Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS
Publication Date: 2020-06

Variant appearance in text: EGFR: A755G
PubMed Link: 32461694
Variant Present in the following documents:
  • NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx, sheet 2
View BVdb publication page



Population pharmacokinetics of afatinib and exposure-safety relationships in Japanese patients with EGFR mutation-positive non-small cell lung cancer.

Scientific Reports
Nakao, Keiko K; Kobuchi, Shinji S; Marutani, Shuhei S; Iwazaki, Ayano A; Tamiya, Akihiro A; Isa, Shunichi S; Okishio, Kyoichi K; Kanazu, Masaki M; Tamiya, Motohiro M; Hirashima, Tomonori T; Imai, Kimie K; Sakaeda, Toshiyuki T; Atagi, Shinji S
Publication Date: 2019-12-03

Variant appearance in text: EGFR: A755G
PubMed Link: 31796841
Variant Present in the following documents:
  • Main text
  • 41598_2019_Article_54804.pdf
View BVdb publication page



Analysis on GENIE reveals novel recurrent variants that affect molecular diagnosis of sizable number of cancer patients.

Bmc Cancer
Koyama, Takahiko T; Rhrissorrakrai, Kahn K; Parida, Laxmi L
Publication Date: 2019-02-01

Variant appearance in text: EGFR: 2264C>G; A755G
PubMed Link: 30709382
Variant Present in the following documents:
  • 12885_2019_5313_MOESM2_ESM.xlsx, sheet 1
  • 12885_2019_5313_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Comprehensive targeted super-deep next generation sequencing enhances differential diagnosis of solitary pulmonary nodules.

Journal Of Thoracic Disease
Ye, Mingzhi M; Li, Shiyong S; Huang, Weizhe W; Wang, Chunli C; Liu, Liping L; Liu, Jun J; Liu, Jilong J; Pan, Hui H; Deng, Qiuhua Q; Tang, Hailing H; Jiang, Long L; Huang, Weizhe W; Chen, Xi X; Shao, Di D; Peng, Zhiyu Z; Wu, Renhua R; Zhong, Jing J; Wang, Zhe Z; Zhang, Xiaoping X; Kristiansen, Karsten K; Wang, Jian J; Yin, Ye Y; Mao, Mao M; He, Jianxing J; Liang, Wenhua W
Publication Date: 2018-04

Variant appearance in text: EGFR: Ala755Gly
PubMed Link: 29780628
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clinical mutational profiling of 1006 lung cancers by next generation sequencing.

Oncotarget
Illei, Peter B PB; Belchis, Deborah D; Tseng, Li-Hui LH; Nguyen, Doreen D; De Marchi, Federico F; Haley, Lisa L; Riel, Stacy S; Beierl, Katie K; Zheng, Gang G; Brahmer, Julie R JR; Askin, Frederic B FB; Gocke, Christopher D CD; Eshleman, James R JR; Forde, Patrick M PM; Lin, Ming-Tseh MT
Publication Date: 2017-11-14

Variant appearance in text: EGFR: 2264C>G
PubMed Link: 29228562
Variant Present in the following documents:
  • oncotarget-08-96684.pdf
View BVdb publication page



Routine genetic testing of lung cancer specimens derived from surgery, bronchoscopy and fluid aspiration by next generation sequencing.

International Journal Of Oncology
Yamamoto, Gou G; Kikuchi, Mari M; Kobayashi, Shiho S; Arai, Yoshiko Y; Fujiyoshi, Kenji K; Wakatsuki, Tomokazu T; Kakuta, Miho M; Yamane, Yuki Y; Iijima, Yoshihito Y; Mizutani, Hideaki H; Nakajima, Yuki Y; Sudo, Junko J; Kinoshita, Hiroyasu H; Kurimoto, Futoshi F; Akiyama, Hirohiko H; Uramoto, Hidetaka H; Sakai, Hiroshi H; Akagi, Yoshito Y; Akagi, Kiwamu K
Publication Date: 2017-05

Variant appearance in text: EGFR: A755G
PubMed Link: 28350094
Variant Present in the following documents:
  • Main text
  • ijo-50-05-1579.pdf
View BVdb publication page