EGFR c.2293G>T ;(p.V765L)

Variant ID: 7-55248995-G-T

NM_005228.3(EGFR):c.2293G>T;(p.V765L)

This variant was identified in 11 publications

View GRCh38 version.




Publications:


Dynamics of Sequence and Structural Cell-Free DNA Landscapes in Small-Cell Lung Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Sivapalan, Lavanya L; Iams, Wade T WT; Belcaid, Zineb Z; Scott, Susan C SC; Niknafs, Noushin N; Balan, Archana A; White, James R JR; Kopparapu, Prasad P; Cann, Christopher C; Landon, Blair V BV; Pereira, Gavin G; Velculescu, Victor E VE; Hann, Christine L CL; Lovly, Christine M CM; Anagnostou, Valsamo V
Publication Date: 2023-04-18

Variant appearance in text: EGFR: V765L
PubMed Link: 37071497
Variant Present in the following documents:
  • ccr-22-2242_ts1-9_suppts1-9.xlsx, sheet 6
View BVdb publication page



A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.

Genome Research
Chen, Siwei S; Liu, Yuan Y; Zhang, Yingying Y; Wierbowski, Shayne D SD; Lipkin, Steven M SM; Wei, Xiaomu X; Yu, Haiyuan H
Publication Date: 2022-01

Variant appearance in text: EGFR: V765L
PubMed Link: 34963661
Variant Present in the following documents:
  • supp_gr.275437.121_Supplementary_Table_1.xlsx, sheet 3
View BVdb publication page



Integrative Bioinformatics approaches to therapeutic gene target selection in various cancers for Nitroglycerin.

Scientific Reports
Chinnappan, Jayaprakash J; Ramu, Akilandeswari A; V, Vidhya Rajalakshmi VR; S, Akil Kavya AK
Publication Date: 2021-11-11

Variant appearance in text: EGFR: V765L
PubMed Link: 34764329
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_1508.pdf
View BVdb publication page



Structure-based classification predicts drug response in EGFR-mutant NSCLC.

Nature
Robichaux, Jacqulyne P JP; Le, Xiuning X; Vijayan, R S K RSK; Hicks, J Kevin JK; Heeke, Simon S; Elamin, Yasir Y YY; Lin, Heather Y HY; Udagawa, Hibiki H; Skoulidis, Ferdinandos F; Tran, Hai H; Varghese, Susan S; He, Junqin J; Zhang, Fahao F; Nilsson, Monique B MB; Hu, Lemei L; Poteete, Alissa A; Rinsurongkawong, Waree W; Zhang, Xiaoshan X; Ren, Chenghui C; Liu, Xiaoke X; Hong, Lingzhi L; Zhang, Jianjun J; Diao, Lixia L; Madison, Russell R; Schrock, Alexa B AB; Saam, Jennifer J; Raymond, Victoria V; Fang, Bingliang B; Wang, Jing J; Ha, Min Jin MJ; Cross, Jason B JB; Gray, Jhanelle E JE; Heymach, John V JV
Publication Date: 2021-09

Variant appearance in text: EGFR: V765L
PubMed Link: 34526717
Variant Present in the following documents:
  • Main text
  • 41586_2021_Article_3898.pdf
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2293G>T; V765L
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports
Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA
Publication Date: 2020-09-21

Variant appearance in text: EGFR: V765L
PubMed Link: 32958805
Variant Present in the following documents:
  • 41598_2020_72404_MOESM2_ESM.xlsx, sheet 3
View BVdb publication page



Specific TP53 subtype as biomarker for immune checkpoint inhibitors in lung adenocarcinoma.

Ebiomedicine
Sun, Hao H; Liu, Si-Yang SY; Zhou, Jia-Ying JY; Xu, Jin-Tian JT; Zhang, Huang-Kai HK; Yan, Hong-Hong HH; Huan, Jiao-Jiao JJ; Dai, Ping-Ping PP; Xu, Chong-Rui CR; Su, Jian J; Guan, Yan-Fang YF; Yi, Xin X; Yu, Rong-Shan RS; Zhong, Wen-Zhao WZ; Wu, Yi-Long YL
Publication Date: 2020-10

Variant appearance in text: EGFR: 2293G>T; V765L
PubMed Link: 32927274
Variant Present in the following documents:
  • mmc2.xlsx, sheet 1
View BVdb publication page



Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Ikemura, Shinnosuke S; Yasuda, Hiroyuki H; Matsumoto, Shingo S; Kamada, Mayumi M; Hamamoto, Junko J; Masuzawa, Keita K; Kobayashi, Keigo K; Manabe, Tadashi T; Arai, Daisuke D; Nakachi, Ichiro I; Kawada, Ichiro I; Ishioka, Kota K; Nakamura, Morio M; Namkoong, Ho H; Naoki, Katsuhiko K; Ono, Fumie F; Araki, Mitsugu M; Kanada, Ryo R; Ma, Biao B; Hayashi, Yuichiro Y; Mimaki, Sachiyo S; Yoh, Kiyotaka K; Kobayashi, Susumu S SS; Kohno, Takashi T; Okuno, Yasushi Y; Goto, Koichi K; Tsuchihara, Katsuya K; Soejima, Kenzo K
Publication Date: 2019-05-14

Variant appearance in text: EGFR: V765L
PubMed Link: 31043566
Variant Present in the following documents:
  • pnas.1819430116.sapp.pdf
View BVdb publication page



Deciphering mechanisms of acquired T790M mutation after EGFR inhibitors for NSCLC by computational simulations.

Scientific Reports
Zou, Bin B; Lee, Victor H F VHF; Chen, Lijiang L; Ma, Lichun L; Wang, Debby D DD; Yan, Hong H
Publication Date: 2017-07-26

Variant appearance in text: EGFR: V765L
PubMed Link: 28747773
Variant Present in the following documents:
  • Main text
  • 41598_2017_Article_6632.pdf
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: ERBB: 2293G>T
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086-s3.xlsx, sheet 1
View BVdb publication page