Publications:

Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket.

Chemical Science

Kannan, Srinivasaraghavan S; Venkatachalam, Gireedhar G; Lim, Hong Hwa HH; Surana, Uttam U; Verma, Chandra C

Publication Date: 2018-06-21

Variant appearance in text: EGFR: M766F

PubMed Link: 29997876

Variant Present in the following documents:

• Main text
• SC-009-C8SC01262H.pdf

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Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib.

Scientific Reports

Kannan, Srinivasaraghavan S; Pradhan, Mohan R MR; Tiwari, Garima G; Tan, Wei-Chong WC; Chowbay, Balram B; Tan, Eng Huat EH; Tan, Daniel Shao-Weng DS; Verma, Chandra C

Publication Date: 2017-05-08

Variant appearance in text: EGFR: M766F

PubMed Link: 28484248

Variant Present in the following documents:

• Main text
• 41598_2017_Article_1491.pdf

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Computational and Experimental Characterization of Patient Derived Mutations Reveal an Unusual Mode of Regulatory Spine Assembly and Drug Sensitivity in EGFR Kinase.

Biochemistry

Ruan, Zheng Z; Katiyar, Samiksha S; Kannan, Natarajan N

Publication Date: 2017-01-10

Variant appearance in text: EGFR: M766F

PubMed Link: 27936599

Variant Present in the following documents:

• Main text

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