Utilizing phenotypic characteristics of metastatic brain tumors to improve the probability of detecting circulating tumor DNA from cerebrospinal fluid in non-small-cell lung cancer patients: development and validation of a prediction model in a prospective cohort study.
Esmo Open
Li, M M; Hou, X X; Zheng, L L; Ma, Y Y; Li, D D; Lv, Y Y; Chen, J J; Zheng, W W; Shao, Y Y; Mou, Y Y; Chen, L L
A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses.
Cancers
Koopman, Bart B; Cajiao Garcia, Betzabel N BN; Kuijpers, Chantal C H J CCHJ; Damhuis, Ronald A M RAM; van der Wekken, Anthonie J AJ; Groen, Harry J M HJM; Schuuring, Ed E; Willems, Stefan M SM; van Kempen, Léon C LC
Longitudinal Circulating Tumor DNA Analysis in Blood and Saliva for Prediction of Response to Osimertinib and Disease Progression in EGFR-Mutant Lung Adenocarcinoma.
Cancers
Kim, Chul C; Xi, Liqiang L; Cultraro, Constance M CM; Wei, Fang F; Jones, Gregory G; Cheng, Jordan J; Shafiei, Ahmad A; Pham, Trinh Hoc-Tran TH; Roper, Nitin N; Akoth, Elizabeth E; Ghafoor, Azam A; Misra, Vikram V; Monkash, Nina N; Strom, Charles C; Tu, Michael M; Liao, Wei W; Chia, David D; Morris, Clive C; Steinberg, Seth M SM; Bagheri, Hadi H; Wong, David T W DTW; Raffeld, Mark M; Guha, Udayan U
Spatially interacting phosphorylation sites and mutations in cancer.
Nature Communications
Huang, Kuan-Lin KL; Scott, Adam D AD; Zhou, Daniel Cui DC; Wang, Liang-Bo LB; Weerasinghe, Amila A; Elmas, Abdulkadir A; Liu, Ruiyang R; Wu, Yige Y; Wendl, Michael C MC; Wyczalkowski, Matthew A MA; Baral, Jessika J; Sengupta, Sohini S; Lai, Chin-Wen CW; Ruggles, Kelly K; Payne, Samuel H SH; Raphael, Benjamin B; Fenyö, David D; Chen, Ken K; Mills, Gordon G; Ding, Li L
Identification of relevant genetic alterations in cancer using topological data analysis.
Nature Communications
Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG
Liquid biopsy mutation panel for non-small cell lung cancer: analytical validation and clinical concordance.
Npj Precision Oncology
Schwartzberg, Lee S LS; Horinouchi, Hidehito H; Chan, David D; Chernilo, Sara S; Tsai, Michaela L ML; Isla, Dolores D; Escriu, Carles C; Bennett, John P JP; Clark-Langone, Kim K; Svedman, Christer C; Tomasini, Pascale P; ,
Tumor Analyses Reveal Squamous Transformation and Off-Target Alterations As Early Resistance Mechanisms to First-line Osimertinib in EGFR-Mutant Lung Cancer.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Schoenfeld, Adam J AJ; Chan, Joseph M JM; Kubota, Daisuke D; Sato, Hiroki H; Rizvi, Hira H; Daneshbod, Yahya Y; Chang, Jason C JC; Paik, Paul K PK; Offin, Michael M; Arcila, Maria E ME; Davare, Monika A MA; Shinde, Ujwal U; Pe'er, Dana D; Rekhtman, Natasha N; Kris, Mark G MG; Somwar, Romel R; Riely, Gregory J GJ; Ladanyi, Marc M; Yu, Helena A HA
Survival Disparities in Black Patients With EGFR-mutated Non-small-cell Lung Cancer.
Clinical Lung Cancer
Cheng, Haiying H; Hosgood, H Dean HD; Deng, Lei L; Ye, Kenny K; Su, Christopher C; Sharma, Janaki J; Yang, Yuanquan Y; Halmos, Balazs B; Perez-Soler, Roman R
[Characteristics of Epidermal Growth Factor Receptor with Rare Mutations in Non-small Cell Lung Cancer and the Effect of EGFR Tyrosine Kinase Inhibitors on Them].
Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
MHC class II restricted neoantigen peptides predicted by clonal mutation analysis in lung adenocarcinoma patients: implications on prognostic immunological biomarker and vaccine design.
Integrative omics analyses broaden treatment targets in human cancer.
Genome Medicine
Sengupta, Sohini S; Sun, Sam Q SQ; Huang, Kuan-Lin KL; Oh, Clara C; Bailey, Matthew H MH; Varghese, Rajees R; Wyczalkowski, Matthew A MA; Ning, Jie J; Tripathi, Piyush P; McMichael, Joshua F JF; Johnson, Kimberly J KJ; Kandoth, Cyriac C; Welch, John J; Ma, Cynthia C; Wendl, Michael C MC; Payne, Samuel H SH; Fenyö, David D; Townsend, Reid R RR; Dipersio, John F JF; Chen, Feng F; Ding, Li L
Frequency, impact and a preclinical study of novel ERBB gene family mutations in HER2-positive breast cancer.
Therapeutic Advances In Medical Oncology
Elster, Naomi N; Toomey, Sinead S; Fan, Yue Y; Cremona, Mattia M; Morgan, Clare C; Weiner Gorzel, Karolina K; Bhreathnach, Una U; Milewska, Malgorzata M; Murphy, Madeline M; Madden, Stephen S; Naidoo, Jarushka J; Fay, Joanna J; Kay, Elaine E; Carr, Aoife A; Kennedy, Sean S; Furney, Simon S; Mezynski, Janusz J; Breathhnach, Oscar O; Morris, Patrick P; Grogan, Liam L; Hill, Arnold A; Kennedy, Susan S; Crown, John J; Gallagher, William W; Hennessy, Bryan B; Eustace, Alex A
Genomic Features of Response to Combination Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer.
Cancer Cell
Hellmann, Matthew D MD; Nathanson, Tavi T; Rizvi, Hira H; Creelan, Benjamin C BC; Sanchez-Vega, Francisco F; Ahuja, Arun A; Ni, Ai A; Novik, Jacki B JB; Mangarin, Levi M B LMB; Abu-Akeel, Mohsen M; Liu, Cailian C; Sauter, Jennifer L JL; Rekhtman, Natasha N; Chang, Eliza E; Callahan, Margaret K MK; Chaft, Jamie E JE; Voss, Martin H MH; Tenet, Megan M; Li, Xue-Mei XM; Covello, Kelly K; Renninger, Andrea A; Vitazka, Patrik P; Geese, William J WJ; Borghaei, Hossein H; Rudin, Charles M CM; Antonia, Scott J SJ; Swanton, Charles C; Hammerbacher, Jeff J; Merghoub, Taha T; McGranahan, Nicholas N; Snyder, Alexandra A; Wolchok, Jedd D JD
Clinical value of the new International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society classification of lung adenocarcinoma.
Comparison of Prevalence and Types of Mutations in Lung Cancers Among Black and White Populations.
Jama Oncology
Campbell, Joshua D JD; Lathan, Christopher C; Sholl, Lynette L; Ducar, Matthew M; Vega, Mikenah M; Sunkavalli, Ashwini A; Lin, Ling L; Hanna, Megan M; Schubert, Laura L; Thorner, Aaron A; Faris, Nicholas N; Williams, David R DR; Osarogiagbon, Raymond U RU; van Hummelen, Paul P; Meyerson, Matthew M; MacConaill, Laura L
Non-classic EGFR mutations in a cohort of Dutch EGFR-mutated NSCLC patients and outcomes following EGFR-TKI treatment.
British Journal Of Cancer
Kuiper, J L JL; Hashemi, S M S SM; Thunnissen, E E; Snijders, P J F PJ; Grünberg, K K; Bloemena, E E; Sie, D D; Postmus, P E PE; Heideman, D A M DA; Smit, E F EF
Assessing the clinical value of targeted massively parallel sequencing in a longitudinal, prospective population-based study of cancer patients.
British Journal Of Cancer
Wong, S Q SQ; Fellowes, A A; Doig, K K; Ellul, J J; Bosma, T J TJ; Irwin, D D; Vedururu, R R; Tan, A Y-C AY; Weiss, J J; Chan, K S KS; Lucas, M M; Thomas, D M DM; Dobrovic, A A; Parisot, J P JP; Fox, S B SB
Publication Date: 2015-04-14
Variant appearance in text: EGFR: 2305G>C; Val769Leu
Identification of EGFR Mutations by Immunohistochemistry with EGFR Mutation-Specific Antibodies in Biopsy and Resection Specimens from Pulmonary Adenocarcinoma.
Cancer Research And Treatment
Kim, Chi Hong CH; Kim, Seung Hoon SH; Park, Sonya Youngju SY; Yoo, Jinyoung J; Kim, Sung Kyoung SK; Kim, Hoon Kyo HK
Structure-based network analysis of activation mechanisms in the ErbB family of receptor tyrosine kinases: the regulatory spine residues are global mediators of structural stability and allosteric interactions.
Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B