EGFR c.2309A>G ;(p.D770G)

Variant ID: 7-55249011-A-G

NM_005228.3(EGFR):c.2309A>G;(p.D770G)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Prevalence of Epidermal Growth Factor Receptor Exon 20 Insertion Mutations in Non-small-Cell Lung Cancer in Europe: A Pragmatic Literature Review and Meta-analysis.

Targeted Oncology
Van Sanden, Suzy S; Murton, Molly M; Bobrowska, Anna A; Rahhali, Nora N; Sermon, Jan J; Rodrigues, Bernardo B; Goff-Leggett, Danielle D; Chouaid, Christos C; Sebastian, Martin M; Greystoke, Alastair A
Publication Date: 2022-03

Variant appearance in text: EGFR: D770G
PubMed Link: 35226283
Variant Present in the following documents:
  • Main text
  • 11523_2022_Article_868.pdf
View BVdb publication page



Utilizing phenotypic characteristics of metastatic brain tumors to improve the probability of detecting circulating tumor DNA from cerebrospinal fluid in non-small-cell lung cancer patients: development and validation of a prediction model in a prospective cohort study.

Esmo Open
Li, M M; Hou, X X; Zheng, L L; Ma, Y Y; Li, D D; Lv, Y Y; Chen, J J; Zheng, W W; Shao, Y Y; Mou, Y Y; Chen, L L
Publication Date: 2022-02

Variant appearance in text: EGFR: D770G
PubMed Link: 34922300
Variant Present in the following documents:
  • mmc1.xlsx, sheet 1
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: D770G
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Response Heterogeneity of EGFR and HER2 Exon 20 Insertions to Covalent EGFR and HER2 Inhibitors.

Cancer Research
Kosaka, Takayuki T; Tanizaki, Junko J; Paranal, Raymond M RM; Endoh, Hideki H; Lydon, Christine C; Capelletti, Marzia M; Repellin, Claire E CE; Choi, Jihyun J; Ogino, Atsuko A; Calles, Antonio A; Ercan, Dalia D; Redig, Amanda J AJ; Bahcall, Magda M; Oxnard, Geoffrey R GR; Eck, Michael J MJ; Jänne, Pasi A PA
Publication Date: 2017-05-15

Variant appearance in text: EGFR: Asp770Gly
PubMed Link: 28363995
Variant Present in the following documents:
  • Main text
View BVdb publication page



Common and rare EGFR and KRAS mutations in a Dutch non-small-cell lung cancer population and their clinical outcome.

Plos One
Kerner, Gerald S M A GS; Schuuring, Ed E; Sietsma, Johanna J; Hiltermann, Thijo J N TJ; Pieterman, Remge M RM; de Leede, Gerard P J GP; van Putten, John W G JW; Liesker, Jeroen J; Renkema, Tineke E J TE; van Hengel, Peter P; Platteel, Inge I; Timens, Wim W; Groen, Harry J M HJ; ,
Publication Date: 2013

Variant appearance in text: EGFR: D770G
PubMed Link: 23922984
Variant Present in the following documents:
  • Main text
View BVdb publication page



Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells.

Nature Biotechnology
Taipale, Mikko M; Krykbaeva, Irina I; Whitesell, Luke L; Santagata, Sandro S; Zhang, Jianming J; Liu, Qingsong Q; Gray, Nathanael S NS; Lindquist, Susan S
Publication Date: 2013-07

Variant appearance in text: EGFR: D770G
PubMed Link: 23811600
Variant Present in the following documents:
  • Main text
  • nihms484224.pdf
View BVdb publication page