EGFR c.2310_2311insGGT ;(p.D770_N771insG)

Variant ID: 7-55249012-C-CGGT

NM_005228.3(EGFR):c.2310_2311insGGT;(p.D770_N771insG)

This variant was identified in 57 publications

View GRCh38 version.




Publications:


Phase 1b trial of anti-EGFR antibody JMT101 and Osimertinib in EGFR exon 20 insertion-positive non-small-cell lung cancer.

Nature Communications
Zhao, Shen S; Zhuang, Wu W; Han, Baohui B; Song, Zhengbo Z; Guo, Wei W; Luo, Feng F; Wu, Lin L; Hu, Yi Y; Wang, Huijuan H; Dong, Xiaorong X; Jiang, Da D; Wang, Mingxia M; Miao, Liyun L; Wang, Qian Q; Zhang, Junping J; Fu, Zhenming Z; Huang, Yihua Y; Xu, Chunwei C; Hu, Longyu L; Li, Lei L; Hu, Rong R; Yang, Yang Y; Li, Mengke M; Yang, Xiugao X; Zhang, Li L; Huang, Yan Y; Fang, Wenfeng W
Publication Date: 2023-06-12

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 37308490
Variant Present in the following documents:
  • 41467_2023_39139_MOESM4_ESM.xlsx, sheet 23
  • 41467_2023_39139_MOESM4_ESM.xlsx, sheet 3
View BVdb publication page



Development and validation of a mutation-based model to predict immunotherapeutic efficacy in NSCLC.

Frontiers In Oncology
He, Ping P; Liu, Jie J; Xu, Qingyuan Q; Ma, Huaijun H; Niu, Beifang B; Huang, Gang G; Wu, Wei W
Publication Date: 2023

Variant appearance in text: EGFR: 2310_2311insGGT
PubMed Link: 36910641
Variant Present in the following documents:
  • DataSheet_1.xlsx, sheet 8
View BVdb publication page



Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery
Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI
Publication Date: 2023-03-02

Variant appearance in text: EGFR: 2310_2311insGGT; Asp770_Asn771insGly
PubMed Link: 36862804
Variant Present in the following documents:
  • cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 6
View BVdb publication page



Case report: olaparib use in metastatic lung adenocarcinoma with BRCA2 pathogenic variant.

Cold Spring Harbor Molecular Case Studies
Soon Jian Hao, Jonathan J; Hoai, Chan Sock CS; Weng, Daniel Tan Shao DTS; Ngeow, Joanne J; Chiang, Jianbang J
Publication Date: 2022-12

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 36577523
Variant Present in the following documents:
  • supp_mcs.a006223_Supplemental_Material.pdf
View BVdb publication page



An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology
Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y
Publication Date: 2022

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 36505399
Variant Present in the following documents:
  • Table_2.xlsx, sheet 3
  • Table_2.xlsx, sheet 2
View BVdb publication page



Analytical and clinical validation of a custom 15-gene next-generation sequencing panel for the evaluation of circulating tumor DNA mutations in patients with advanced non-small-cell lung cancer.

Plos One
Chow, Yock Ping YP; Zainul Abidin, Norziha N; Kow, Ken Siong KS; Tho, Lye Mun LM; Wong, Chieh Lee CL
Publication Date: 2022

Variant appearance in text: EGFR: D770_N771insG
PubMed Link: 36256645
Variant Present in the following documents:
  • Main text
  • pone.0276161.pdf
  • pone.0276161.s002.xlsx, sheet 1
View BVdb publication page



Landscape of EGFR mutations in lung adenocarcinoma: a single institute experience with comparison of PANAMutyper testing and targeted next-generation sequencing.

Journal Of Pathology And Translational Medicine
Lee, Jeonghyo J; Han, Yeon Bi YB; Kwon, Hyun Jung HJ; Lee, Song Kook SK; Kim, Hyojin H; Chung, Jin-Haeng JH
Publication Date: 2022-09

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 36128861
Variant Present in the following documents:
  • jptm-2022-06-11-suppl1.pdf
View BVdb publication page



Modified Taq DNA Polymerase for Allele-Specific Ultra-Sensitive Detection of Genetic Variants.

The Journal Of Molecular Diagnostics : Jmd
Lim, Youngshin Y; Park, Il-Hyun IH; Lee, Huy-Ho HH; Baek, Kyuwon K; Lee, Byung-Chul BC; Cho, Ginam G
Publication Date: 2022-11

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 36058471
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Comprehensive characterization of genomic and radiologic features reveals distinct driver patterns of RTK/RAS pathway in ground-glass opacity pulmonary nodules.

International Journal Of Cancer
Yu, Fenglei F; Peng, Muyun M; Bai, Jing J; Zhu, Xiuli X; Zhang, Bingyu B; Tang, Jingqun J; Liu, Wenliang W; Chen, Chen C; Wang, Xiang X; Chen, Mingjiu M; Tan, Sichuang S; Sun, Yi Y; Liang, Qingchun Q; Li, Jina J; Hu, Yan Y; Liao, Aihui A; Hu, Huali H; He, Yu Y; Xiao, Xiao X; Wang, Bin B; Xing, Guanlan G; Xu, Yaping Y; Chen, Rongrong R; Xia, Xuefeng X; Chen, Xiaofeng X
Publication Date: 2022-12-01

Variant appearance in text: EGFR: D770_N771insG
PubMed Link: 36029220
Variant Present in the following documents:
  • IJC-151-2020-s001.pdf
  • IJC-151-2020.pdf
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 35936718
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine
Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R
Publication Date: 2022-05

Variant appearance in text: EGFR: 2310_2311insGGT; Asp770_Asn771insGly
PubMed Link: 35244186
Variant Present in the following documents:
  • Supplementary_Data3.xlsx, sheet 1
View BVdb publication page



Preparation of multiplexed control materials for cancer mutation analysis by genome editing in GM12878 cells.

Journal Of Clinical Laboratory Analysis
Lin, Guigao G; Zhang, Kuo K; Han, Yanxi Y; Peng, Rongxue R; Li, Jinming J
Publication Date: 2022-01

Variant appearance in text: EGFR: 2310_2311insGGT
PubMed Link: 34811797
Variant Present in the following documents:
  • Main text
View BVdb publication page



R-Score: A New Parameter to Assess the Quality of Variants' Calls Assessed by NGS Using Liquid Biopsies.

Biology
Serna-Blasco, Roberto R; Sánchez-Herrero, Estela E; Berrocal Renedo, María M; Calabuig-Fariñas, Silvia S; Molina-Vila, Miguel Ángel MÁ; Provencio, Mariano M; Romero, Atocha A
Publication Date: 2021-09-24

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 34681053
Variant Present in the following documents:
  • Main text
  • biology-10-00954.pdf
View BVdb publication page



EGFR Exon 20 Insertion in Metastatic Non-Small-Cell Lung Cancer: Survival and Clinical Efficacy of EGFR Tyrosine-Kinase Inhibitor and Chemotherapy.

Cancers
Chelabi, Samy S; Mignard, Xavier X; Leroy, Karen K; Monnet, Isabelle I; Brosseau, Solenn S; Theou-Anton, Nathalie N; Massiani, Marie-Ange MA; Friard, Sylvie S; Duchemann, Boris B; Fabre, Elizabeth E; Giroux-Leprieur, Etienne E; Cadranel, Jacques J; Wislez, Marie M
Publication Date: 2021-10-13

Variant appearance in text: EGFR: Asp770_Asn771insGly
PubMed Link: 34680280
Variant Present in the following documents:
  • Main text
View BVdb publication page



Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine
Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z
Publication Date: 2021-10

Variant appearance in text: EGFR: Asp770_Asn771insGly
PubMed Link: 34599863
Variant Present in the following documents:
  • CAM4-10-7360-s002.xlsx, sheet 2
View BVdb publication page



Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine
Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z
Publication Date: 2021-10

Variant appearance in text: EGFR: Asp770_Asn771insGly
PubMed Link: 34599863
Variant Present in the following documents:
  • CAM4-10-7360-s002.xlsx, sheet 2
View BVdb publication page



The immune microenvironment in EGFR- and ERBB2-mutated lung adenocarcinoma.

Esmo Open
Kirchner, M M; Kluck, K K; Brandt, R R; Volckmar, A-L AL; Penzel, R R; Kazdal, D D; Endris, V V; Neumann, O O; Seker-Cin, H H; Goldschmid, H H; Glade, J J; Allgäuer, M M; Kriegsmann, M M; Winter, H H; Muley, T T; Perner, S S; Frost, N N; Reck, M M; Fröhling, S S; Schirmacher, P P; Thomas, M M; Budczies, J J; Christopoulos, P P; Stenzinger, A A
Publication Date: 2021-10

Variant appearance in text: EGFR: Asp770_Asn771insGly
PubMed Link: 34487971
Variant Present in the following documents:
  • mmc1.xlsx, sheet 1
View BVdb publication page



Dynamic Evaluation of Circulating miRNA Profile in EGFR-Mutated NSCLC Patients Treated with EGFR-TKIs.

Cells
Leonetti, Alessandro A; Capula, Mjriam M; Minari, Roberta R; Mazzaschi, Giulia G; Gregori, Alessandro A; El Hassouni, Btissame B; Papini, Filippo F; Bordi, Paola P; Verzè, Michela M; Avan, Amir A; Tiseo, Marcello M; Giovannetti, Elisa E
Publication Date: 2021-06-16

Variant appearance in text: EGFR: 2310_2311insGGT
PubMed Link: 34208765
Variant Present in the following documents:
  • Main text
  • cells-10-01520.pdf
View BVdb publication page



Evaluation of the Idylla ctEGFR mutation assay to detect EGFR mutations in plasma from patients with non-small cell lung cancers.

Scientific Reports
Gilson, Pauline P; Saurel, Chloé C; Salleron, Julia J; Husson, Marie M; Demange, Jessica J; Merlin, Jean-Louis JL; Harlé, Alexandre A
Publication Date: 2021-05-18

Variant appearance in text: EGFR: 2310_2311insGGT
PubMed Link: 34006948
Variant Present in the following documents:
  • 41598_2021_90091_MOESM2_ESM.pdf
View BVdb publication page



Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Clinical impact of rebiopsy among patients with epidermal growth factor receptor-mutant lung adenocarcinoma in a real-world clinical setting.

Thoracic Cancer
Nam, Yunha Y; Kim, Ho Cheol HC; Kim, Young-Chul YC; Jang, Seung Hun SH; Lee, Kye Young KY; Lee, Shin Yup SY; Lee, Sang Hoon SH; Lee, Sung Yong SY; Yoon, Seong Hoon SH; Ryu, Jeong-Seon JS; Jang, Tae Won TW; Chang, Yoon Soo YS; Kim, Seung Joon SJ; Park, Chan Kwon CK; Lee, Jeong Eun JE; Jung, Chi Young CY; Choi, Chang-Min CM
Publication Date: 2021-03

Variant appearance in text: EGFR: D770_n771insG
PubMed Link: 33529490
Variant Present in the following documents:
  • Main text
  • TCA-12-890.pdf
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
  • 41467_2020_20162_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Impact of EGFR amplification on survival of patients with EGFR exon 20 insertion-positive non-small cell lung cancer.

Journal Of Thoracic Disease
Gao, Xin X; Wei, Xue-Wu XW; Zheng, Ming-Ying MY; Chen, Zhi-Hong ZH; Zhang, Xu-Chao XC; Zhong, Wen-Zhao WZ; Yang, Jin-Ji JJ; Wu, Yi-Long YL; Zhou, Qing Q
Publication Date: 2020-10

Variant appearance in text: EGFR: D770_N771insG
PubMed Link: 33209414
Variant Present in the following documents:
  • jtd-12-10-5822.pdf
View BVdb publication page



Mass Spectrometry as a Highly Sensitive Method for Specific Circulating Tumor DNA Analysis in NSCLC: A Comparison Study.

Cancers
Lamy, Pierre-Jean PJ; van der Leest, Paul P; Lozano, Nicolas N; Becht, Catherine C; Duboeuf, Frédérique F; Groen, Harry J M HJM; Hilgers, Werner W; Pourel, Nicolas N; Rifaela, Naomi N; Schuuring, Ed E; Alix-Panabières, Catherine C
Publication Date: 2020-10-16

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 33081150
Variant Present in the following documents:
  • cancers-12-03002-s001.pdf
View BVdb publication page



Plasma-based early screening and monitoring of EGFR mutations in NSCLC patients by a 3-color digital PCR assay.

British Journal Of Cancer
Song, Xiang X; Gong, Jian J; Zhang, Xiaoling X; Feng, Xiaoyan X; Huang, Hui H; Gao, Min M; Chu, Li L
Publication Date: 2020-10

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 32782293
Variant Present in the following documents:
  • 41416_2020_1024_MOESM1_ESM.pdf
View BVdb publication page



Variability of EGFR exon 20 insertions in 24 468 Chinese lung cancer patients and their divergent responses to EGFR inhibitors.

Molecular Oncology
Qin, YanRu Y; Jian, Hong H; Tong, Xiaoling X; Wu, Xue X; Wang, Fufeng F; Shao, Yang W YW; Zhao, Xinmin X
Publication Date: 2020-08

Variant appearance in text: EGFR: D770_N771insG
PubMed Link: 32412152
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clinical performance evaluation of the Idylla™ EGFR Mutation Test on formalin-fixed paraffin-embedded tissue of non-small cell lung cancer.

Bmc Cancer
Delgado-García, Mercedes M; Weynand, Birgit B; Gómez-Izquierdo, Lourdes L; Hernández, María José MJ; Blanco, Ángela María ÁM; Varela, Mar M; Matias-Guiu, Xavier X; Nadal, Ernest E; Márquez-Lobo, Bélgica B; Alarcão, Ana A; de Álava, Enrique E; Biscuola, Michele M
Publication Date: 2020-04-03

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 32245434
Variant Present in the following documents:
  • Main text
  • 12885_2020_Article_6697.pdf
View BVdb publication page



Rapid EGFR mutation testing in lung cancer tissue samples using a fully automated system and single-use cartridge.

Practical Laboratory Medicine
Al-Turkmani, M Rabie MR; Suriawinata, Michael A MA; Deharvengt, Sophie J SJ; Green, Donald C DC; Black, Candice C CC; Shirai, Keisuke K; Dragnev, Konstantin H KH; Tsongalis, Gregory J GJ
Publication Date: 2020-05

Variant appearance in text: EGFR: 2310_2311insGGT
PubMed Link: 32181314
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Detection of Targetable Genetic Alterations in Korean Lung Cancer Patients: A Comparison Study of Single-Gene Assays and Targeted Next-Generation Sequencing.

Cancer Research And Treatment
Park, Eunhyang E; Shim, Hyo Sup HS
Publication Date: 2020-04

Variant appearance in text: EGFR: D770_N771insG
PubMed Link: 31726498
Variant Present in the following documents:
  • Main text
  • crt-2019-305.pdf
View BVdb publication page



Targeted Gene Next-Generation Sequencing Panel in Patients with Advanced Lung Adenocarcinoma: Paving the Way for Clinical Implementation.

Cancers
Fernandes, Maria Gabriela O MGO; Jacob, Maria M; Martins, Natália N; Moura, Conceição Souto CS; Guimarães, Susana S; Reis, Joana Pereira JP; Justino, Ana A; Pina, Maria João MJ; Cirnes, Luís L; Sousa, Catarina C; Pinto, Josué J; Marques, José Agostinho JA; Machado, José Carlos JC; Hespanhol, Venceslau V; Costa, José Luis JL
Publication Date: 2019-08-22

Variant appearance in text: EGFR: D770_N771insG
PubMed Link: 31443496
Variant Present in the following documents:
  • cancers-11-01229-s001.pdf
View BVdb publication page



Oncogenic driver mutations in Swiss never smoker patients with lung adenocarcinoma and correlation with clinicopathologic characteristics and outcome.

Plos One
Grosse, Claudia C; Soltermann, Alex A; Rechsteiner, Markus M; Grosse, Alexandra A
Publication Date: 2019

Variant appearance in text: EGFR: D770_N771insG
PubMed Link: 31386689
Variant Present in the following documents:
  • Main text
  • pone.0220691.pdf
View BVdb publication page



Clinical utility of custom-designed NGS panel testing in pediatric tumors.

Genome Medicine
Surrey, Lea F LF; MacFarland, Suzanne P SP; Chang, Fengqi F; Cao, Kajia K; Rathi, Komal S KS; Akgumus, Gozde T GT; Gallo, Daniel D; Lin, Fumin F; Gleason, Adam A; Raman, Pichai P; Aplenc, Richard R; Bagatell, Rochelle R; Minturn, Jane J; Mosse, Yael Y; Santi, Mariarita M; Tasian, Sarah K SK; Waanders, Angela J AJ; Sarmady, Mahdi M; Maris, John M JM; Hunger, Stephen P SP; Li, Marilyn M MM
Publication Date: 2019-05-28

Variant appearance in text: EGFR: 2310_2311insGGT; Asp770_Asn771insGly
PubMed Link: 31133068
Variant Present in the following documents:
  • 13073_2019_644_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Multilaboratory Assessment of a New Reference Material for Quality Assurance of Cell-Free Tumor DNA Measurements.

The Journal Of Molecular Diagnostics : Jmd
He, Hua-Jun HJ; Stein, Erica V EV; Konigshofer, Yves Y; Forbes, Thomas T; Tomson, Farol L FL; Garlick, Russell R; Yamada, Emiko E; Godfrey, Tony T; Abe, Toshiya T; Tamura, Koji K; Borges, Michael M; Goggins, Michael M; Elmore, Sandra S; Gulley, Margaret L ML; Larson, Jessica L JL; Ringel, Lando L; Haynes, Brian C BC; Karlovich, Chris C; Williams, P Mickey PM; Garnett, Aaron A; Ståhlberg, Anders A; Filges, Stefan S; Sorbara, Lynn L; Young, Mathew R MR; Srivastava, Sudhir S; Cole, Kenneth D KD
Publication Date: 2019-07

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 31055023
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Targeted Single Primer Enrichment Sequencing with Single End Duplex-UMI.

Scientific Reports
Peng, Quan Q; Xu, Chang C; Kim, Daniel D; Lewis, Marcus M; DiCarlo, John J; Wang, Yexun Y
Publication Date: 2019-03-18

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 30886209
Variant Present in the following documents:
  • 41598_2019_41215_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Fibroblast growth factor receptor 3 (FGFR3) aberrations in muscle-invasive urothelial carcinoma.

Bmc Urology
Kim, Young Saing YS; Kim, Kyung K; Kwon, Ghee-Young GY; Lee, Su Jin SJ; Park, Se Hoon SH
Publication Date: 2018-07-31

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 30064409
Variant Present in the following documents:
  • 12894_2018_380_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Clinical Outcomes of EGFR Exon 20 Insertion Mutations in Advanced Non-small Cell Lung Cancer in Korea.

Cancer Research And Treatment
Byeon, Seonggyu S; Kim, Youjin Y; Lim, Sung Won SW; Cho, Jang Ho JH; Park, Sehoon S; Lee, Jiyun J; Sun, Jong-Mu JM; Choi, Yoon-La YL; Lee, Se-Hoon SH; Ahn, Jin Seok JS; Park, Keunchil K; Ahn, Myung-Ju MJ
Publication Date: 2019-04

Variant appearance in text: EGFR: D770_N771insG
PubMed Link: 30049203
Variant Present in the following documents:
  • Main text
  • crt-2018-151.pdf
View BVdb publication page



EGFR exon 20 insertion mutation in advanced thymic squamous cell carcinoma: Response to apatinib and clinical outcomes.

Thoracic Cancer
Yudong, Su S; Zhaoting, Meng M; Xinyue, Wang W; Li, Lin L; Xiaoyan, Xu X; Ran, Zuo Z; Jinliang, Chen C; Peng, Chen C
Publication Date: 2018-07

Variant appearance in text: EGFR: Asp770_Asn771insGly
PubMed Link: 29740957
Variant Present in the following documents:
  • Main text
  • TCA-9-885.pdf
View BVdb publication page



Performance of next-generation sequencing on small tumor specimens and/or low tumor content samples using a commercially available platform.

Plos One
Morris, Scott M SM; Subramanian, Janakiraman J; Gel, Esma S ES; Runger, George C GC; Thompson, Eric J EJ; Mallery, David W DW; Weiss, Glen J GJ
Publication Date: 2018

Variant appearance in text: ERBB1: 2310_2311insGGT
PubMed Link: 29702695
Variant Present in the following documents:
  • pone.0196556.s001.xlsx, sheet 1
View BVdb publication page



Feasibility study of cancer genome alterations identified by next generation sequencing: ABC study.

Japanese Journal Of Clinical Oncology
Naito, Yoichi Y; Takahashi, Hideaki H; Shitara, Kohei K; Okamoto, Wataru W; Bando, Hideaki H; Kuwata, Takeshi T; Kuboki, Yasutoshi Y; Matsumoto, Shingo S; Miki, Izumi I; Yamanaka, Takeharu T; Watanabe, Atsushi A; Kojima, Motohiro M
Publication Date: 2018-06-01

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 29659903
Variant Present in the following documents:
  • hyy052supplementaltable1ionver1.xls, sheet 1
View BVdb publication page



Analytical validation of a next generation sequencing liquid biopsy assay for high sensitivity broad molecular profiling.

Plos One
Plagnol, Vincent V; Woodhouse, Samuel S; Howarth, Karen K; Lensing, Stefanie S; Smith, Matt M; Epstein, Michael M; Madi, Mikidache M; Smalley, Sarah S; Leroy, Catherine C; Hinton, Jonathan J; de Kievit, Frank F; Musgrave-Brown, Esther E; Herd, Colin C; Baker-Neblett, Katherine K; Brennan, Will W; Dimitrov, Peter P; Campbell, Nathan N; Morris, Clive C; Rosenfeld, Nitzan N; Clark, James J; Gale, Davina D; Platt, Jamie J; Calaway, John J; Jones, Greg G; Forshew, Tim T
Publication Date: 2018

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 29543828
Variant Present in the following documents:
  • pone.0193802.s007.xlsx, sheet 1
View BVdb publication page



Prognostic value of quantitative ctDNA levels in non small cell lung cancer patients.

Oncotarget
Provencio, Mariano M; Torrente, María M; Calvo, Virginia V; Pérez-Callejo, David D; Gutiérrez, Lourdes L; Franco, Fernando F; Pérez-Barrios, Clara C; Barquín, Miguel M; Royuela, Ana A; García-García, Francisco F; Bueno, Coralia C; Garcia-Grande, Aranzazu A; Camps, Carlos C; Massuti, Bartomeu B; Sotomayor, Eduardo E; Romero, Atocha A
Publication Date: 2018-01-02

Variant appearance in text: EGFR: D770_N771insG
PubMed Link: 29416630
Variant Present in the following documents:
  • Main text
  • oncotarget-09-488.pdf
View BVdb publication page



Droplet digital PCR-based EGFR mutation detection with an internal quality control index to determine the quality of DNA.

Scientific Reports
Kim, Sung-Su SS; Choi, Hyun-Jeung HJ; Kim, Jin Ju JJ; Kim, M Sun MS; Lee, In-Seon IS; Byun, Bohyun B; Jia, Lina L; Oh, Myung Ryurl MR; Moon, Youngho Y; Park, Sarah S; Choi, Joon-Seok JS; Chae, Seoung Wan SW; Nam, Byung-Ho BH; Kim, Jin-Soo JS; Kim, Jihun J; Min, Byung Soh BS; Lee, Jae Seok JS; Won, Jae-Kyung JK; Cho, Soo Youn SY; Choi, Yoon-La YL; Shin, Young Kee YK
Publication Date: 2018-01-11

Variant appearance in text: EGFR: D770_N771insG
PubMed Link: 29323170
Variant Present in the following documents:
  • 41598_2017_18642_MOESM1_ESM.pdf
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Optimization of EGFR mutation detection by the fully-automated qPCR-based Idylla system on tumor tissue from patients with non-small cell lung cancer.

Oncotarget
Ilie, Marius M; Butori, Catherine C; Lassalle, Sandra S; Heeke, Simon S; Piton, Nicolas N; Sabourin, Jean-Christophe JC; Tanga, Virginie V; Washetine, Kevin K; Long-Mira, Elodie E; Maitre, Priscilla P; Yazbeck, Nathalie N; Bordone, Olivier O; Lespinet, Virginie V; Leroy, Sylvie S; Cohen, Charlotte C; Mouroux, Jérôme J; Marquette, Charles Hugo CH; Hofman, Véronique V; Hofman, Paul P
Publication Date: 2017-11-28

Variant appearance in text: EGFR: 2310_2311insGGT
PubMed Link: 29262544
Variant Present in the following documents:
  • oncotarget-08-103055-s003.xlsx, sheet 1
View BVdb publication page



Molecular Characterization of Urothelial Carcinoma of the Bladder and Upper Urinary Tract.

Translational Oncology
Lee, Ji Yun JY; Kim, Kyung K; Sung, Hyun Hwan HH; Jeon, Hwang Gyun HG; Jeong, Byong Chang BC; Seo, Seong Il SI; Jeon, Seong Soo SS; Lee, Hyun Moo HM; Choi, Han-Yong HY; Kwon, Ghee-Young GY; Kim, Kyoung-Mee KM; Lee, Jeeyun J; Lim, Ho Yeong HY; Park, Se Hoon SH
Publication Date: 2018-02

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 29161613
Variant Present in the following documents:
  • mmc1.xlsx, sheet 1
View BVdb publication page



Cancer gene profiling in non-small cell lung cancers reveals activating mutations in JAK2 and JAK3 with therapeutic implications.

Genome Medicine
Li, Shuyu D SD; Ma, Meng M; Li, Hui H; Waluszko, Aneta A; Sidorenko, Tatyana T; Schadt, Eric E EE; Zhang, David Y DY; Chen, Rong R; Ye, Fei F
Publication Date: 2017-10-30

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 29082853
Variant Present in the following documents:
  • 13073_2017_478_MOESM1_ESM.xlsx, sheet 2
View BVdb publication page



Dynamic circulating tumor DNA quantificaton for the individualization of non-small-cell lung cancer patients treatment.

Oncotarget
Provencio, Mariano M; Torrente, María M; Calvo, Virgina V; Gutiérrez, Lourdes L; Pérez-Callejo, David D; Pérez-Barrios, Clara C; Barquín, Miguel M; Royuela, Ana A; Rodriguez-Alfonso, Begoña B; Sotelo, Miguel M; Cruz-Bermúdez, Juan Luis JL; Mendez, Miriam M; Cruz-Bermúdez, Alberto A; Romero, Atocha A
Publication Date: 2017-09-01

Variant appearance in text: EGFR: D770_N771insG
PubMed Link: 28947971
Variant Present in the following documents:
  • Main text
  • oncotarget-08-60291.pdf
View BVdb publication page



Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research
Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U
Publication Date: 2017-04

Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
PubMed Link: 28179366
Variant Present in the following documents:
  • supp_gr.213546.116_Supplemental_Table_S7.xlsx, sheet 1
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Prospective Evaluation of First-Line Erlotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) Carrying an Activating EGFR Mutation: A Multicenter Academic Phase II Study in Caucasian Patients (FIELT).

Plos One
De Grève, Jacques J; Van Meerbeeck, Jan J; Vansteenkiste, Johan F JF; Decoster, Lore L; Meert, Anne-Pascale AP; Vuylsteke, Peter P; Focan, Christian C; Canon, Jean-Luc JL; Humblet, Yves Y; Berchem, Guy G; Colinet, Benoit B; Galdermans, Danny D; Bosquée, Lionel L; Vermeij, Joanna J; Dewaele, Alex A; Geers, Caroline C; Schallier, Denis D; Teugels, Erik E
Publication Date: 2016

Variant appearance in text: EGFR: 2310_2311insGGT; Asp770_Asn771insGly
PubMed Link: 27032107
Variant Present in the following documents:
  • Main text
  • pone.0147599.pdf
View BVdb publication page