Analytical and clinical validation of a custom 15-gene next-generation sequencing panel for the evaluation of circulating tumor DNA mutations in patients with advanced non-small-cell lung cancer.
Plos One
Chow, Yock Ping YP; Zainul Abidin, Norziha N; Kow, Ken Siong KS; Tho, Lye Mun LM; Wong, Chieh Lee CL
Landscape of EGFR mutations in lung adenocarcinoma: a single institute experience with comparison of PANAMutyper testing and targeted next-generation sequencing.
Journal Of Pathology And Translational Medicine
Lee, Jeonghyo J; Han, Yeon Bi YB; Kwon, Hyun Jung HJ; Lee, Song Kook SK; Kim, Hyojin H; Chung, Jin-Haeng JH
Publication Date: 2022-09
Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
Comprehensive characterization of genomic and radiologic features reveals distinct driver patterns of RTK/RAS pathway in ground-glass opacity pulmonary nodules.
Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.
International Journal Of Molecular Medicine
Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R
Publication Date: 2022-05
Variant appearance in text: EGFR: 2310_2311insGGT; Asp770_Asn771insGly
R-Score: A New Parameter to Assess the Quality of Variants' Calls Assessed by NGS Using Liquid Biopsies.
Biology
Serna-Blasco, Roberto R; Sánchez-Herrero, Estela E; Berrocal Renedo, María M; Calabuig-Fariñas, Silvia S; Molina-Vila, Miguel Ángel MÁ; Provencio, Mariano M; Romero, Atocha A
Publication Date: 2021-09-24
Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
The immune microenvironment in EGFR- and ERBB2-mutated lung adenocarcinoma.
Esmo Open
Kirchner, M M; Kluck, K K; Brandt, R R; Volckmar, A-L AL; Penzel, R R; Kazdal, D D; Endris, V V; Neumann, O O; Seker-Cin, H H; Goldschmid, H H; Glade, J J; Allgäuer, M M; Kriegsmann, M M; Winter, H H; Muley, T T; Perner, S S; Frost, N N; Reck, M M; Fröhling, S S; Schirmacher, P P; Thomas, M M; Budczies, J J; Christopoulos, P P; Stenzinger, A A
Publication Date: 2021-10
Variant appearance in text: EGFR: Asp770_Asn771insGly
Clinical impact of rebiopsy among patients with epidermal growth factor receptor-mutant lung adenocarcinoma in a real-world clinical setting.
Thoracic Cancer
Nam, Yunha Y; Kim, Ho Cheol HC; Kim, Young-Chul YC; Jang, Seung Hun SH; Lee, Kye Young KY; Lee, Shin Yup SY; Lee, Sang Hoon SH; Lee, Sung Yong SY; Yoon, Seong Hoon SH; Ryu, Jeong-Seon JS; Jang, Tae Won TW; Chang, Yoon Soo YS; Kim, Seung Joon SJ; Park, Chan Kwon CK; Lee, Jeong Eun JE; Jung, Chi Young CY; Choi, Chang-Min CM
Mass Spectrometry as a Highly Sensitive Method for Specific Circulating Tumor DNA Analysis in NSCLC: A Comparison Study.
Cancers
Lamy, Pierre-Jean PJ; van der Leest, Paul P; Lozano, Nicolas N; Becht, Catherine C; Duboeuf, Frédérique F; Groen, Harry J M HJM; Hilgers, Werner W; Pourel, Nicolas N; Rifaela, Naomi N; Schuuring, Ed E; Alix-Panabières, Catherine C
Publication Date: 2020-10-16
Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
Clinical performance evaluation of the Idylla™ EGFR Mutation Test on formalin-fixed paraffin-embedded tissue of non-small cell lung cancer.
Bmc Cancer
Delgado-García, Mercedes M; Weynand, Birgit B; Gómez-Izquierdo, Lourdes L; Hernández, María José MJ; Blanco, Ángela María ÁM; Varela, Mar M; Matias-Guiu, Xavier X; Nadal, Ernest E; Márquez-Lobo, Bélgica B; Alarcão, Ana A; de Álava, Enrique E; Biscuola, Michele M
Publication Date: 2020-04-03
Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
Rapid EGFR mutation testing in lung cancer tissue samples using a fully automated system and single-use cartridge.
Practical Laboratory Medicine
Al-Turkmani, M Rabie MR; Suriawinata, Michael A MA; Deharvengt, Sophie J SJ; Green, Donald C DC; Black, Candice C CC; Shirai, Keisuke K; Dragnev, Konstantin H KH; Tsongalis, Gregory J GJ
Detection of Targetable Genetic Alterations in Korean Lung Cancer Patients: A Comparison Study of Single-Gene Assays and Targeted Next-Generation Sequencing.
Targeted Gene Next-Generation Sequencing Panel in Patients with Advanced Lung Adenocarcinoma: Paving the Way for Clinical Implementation.
Cancers
Fernandes, Maria Gabriela O MGO; Jacob, Maria M; Martins, Natália N; Moura, Conceição Souto CS; Guimarães, Susana S; Reis, Joana Pereira JP; Justino, Ana A; Pina, Maria João MJ; Cirnes, Luís L; Sousa, Catarina C; Pinto, Josué J; Marques, José Agostinho JA; Machado, José Carlos JC; Hespanhol, Venceslau V; Costa, José Luis JL
Clinical utility of custom-designed NGS panel testing in pediatric tumors.
Genome Medicine
Surrey, Lea F LF; MacFarland, Suzanne P SP; Chang, Fengqi F; Cao, Kajia K; Rathi, Komal S KS; Akgumus, Gozde T GT; Gallo, Daniel D; Lin, Fumin F; Gleason, Adam A; Raman, Pichai P; Aplenc, Richard R; Bagatell, Rochelle R; Minturn, Jane J; Mosse, Yael Y; Santi, Mariarita M; Tasian, Sarah K SK; Waanders, Angela J AJ; Sarmady, Mahdi M; Maris, John M JM; Hunger, Stephen P SP; Li, Marilyn M MM
Publication Date: 2019-05-28
Variant appearance in text: EGFR: 2310_2311insGGT; Asp770_Asn771insGly
Multilaboratory Assessment of a New Reference Material for Quality Assurance of Cell-Free Tumor DNA Measurements.
The Journal Of Molecular Diagnostics : Jmd
He, Hua-Jun HJ; Stein, Erica V EV; Konigshofer, Yves Y; Forbes, Thomas T; Tomson, Farol L FL; Garlick, Russell R; Yamada, Emiko E; Godfrey, Tony T; Abe, Toshiya T; Tamura, Koji K; Borges, Michael M; Goggins, Michael M; Elmore, Sandra S; Gulley, Margaret L ML; Larson, Jessica L JL; Ringel, Lando L; Haynes, Brian C BC; Karlovich, Chris C; Williams, P Mickey PM; Garnett, Aaron A; Ståhlberg, Anders A; Filges, Stefan S; Sorbara, Lynn L; Young, Mathew R MR; Srivastava, Sudhir S; Cole, Kenneth D KD
Publication Date: 2019-07
Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
Analytical validation of a next generation sequencing liquid biopsy assay for high sensitivity broad molecular profiling.
Plos One
Plagnol, Vincent V; Woodhouse, Samuel S; Howarth, Karen K; Lensing, Stefanie S; Smith, Matt M; Epstein, Michael M; Madi, Mikidache M; Smalley, Sarah S; Leroy, Catherine C; Hinton, Jonathan J; de Kievit, Frank F; Musgrave-Brown, Esther E; Herd, Colin C; Baker-Neblett, Katherine K; Brennan, Will W; Dimitrov, Peter P; Campbell, Nathan N; Morris, Clive C; Rosenfeld, Nitzan N; Clark, James J; Gale, Davina D; Platt, Jamie J; Calaway, John J; Jones, Greg G; Forshew, Tim T
Publication Date: 2018
Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
Prognostic value of quantitative ctDNA levels in non small cell lung cancer patients.
Oncotarget
Provencio, Mariano M; Torrente, María M; Calvo, Virginia V; Pérez-Callejo, David D; Gutiérrez, Lourdes L; Franco, Fernando F; Pérez-Barrios, Clara C; Barquín, Miguel M; Royuela, Ana A; García-García, Francisco F; Bueno, Coralia C; Garcia-Grande, Aranzazu A; Camps, Carlos C; Massuti, Bartomeu B; Sotomayor, Eduardo E; Romero, Atocha A
Dynamic circulating tumor DNA quantificaton for the individualization of non-small-cell lung cancer patients treatment.
Oncotarget
Provencio, Mariano M; Torrente, María M; Calvo, Virgina V; Gutiérrez, Lourdes L; Pérez-Callejo, David D; Pérez-Barrios, Clara C; Barquín, Miguel M; Royuela, Ana A; Rodriguez-Alfonso, Begoña B; Sotelo, Miguel M; Cruz-Bermúdez, Juan Luis JL; Mendez, Miriam M; Cruz-Bermúdez, Alberto A; Romero, Atocha A
Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.
Genome Research
Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U
Publication Date: 2017-04
Variant appearance in text: EGFR: 2310_2311insGGT; D770_N771insG
Prospective Evaluation of First-Line Erlotinib in Advanced Non-Small Cell Lung Cancer (NSCLC) Carrying an Activating EGFR Mutation: A Multicenter Academic Phase II Study in Caucasian Patients (FIELT).
Plos One
De Grève, Jacques J; Van Meerbeeck, Jan J; Vansteenkiste, Johan F JF; Decoster, Lore L; Meert, Anne-Pascale AP; Vuylsteke, Peter P; Focan, Christian C; Canon, Jean-Luc JL; Humblet, Yves Y; Berchem, Guy G; Colinet, Benoit B; Galdermans, Danny D; Bosquée, Lionel L; Vermeij, Joanna J; Dewaele, Alex A; Geers, Caroline C; Schallier, Denis D; Teugels, Erik E
Publication Date: 2016
Variant appearance in text: EGFR: 2310_2311insGGT; Asp770_Asn771insGly