EGFR c.2312A>C ;(p.N771T)

Variant ID: 7-55249014-A-C

NM_005228.3(EGFR):c.2312A>C;(p.N771T)

This variant was identified in 15 publications

View GRCh38 version.




Publications:


[Progress in Detection of EGFR Exon 20 Insertion Mutation and Targeted Therapies 
in Non-small Cell Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Wang, Yulu Y; Chu, Tianqing T
Publication Date: 2023-02-20

Variant appearance in text: EGFR: N771T
PubMed Link: 36872052
Variant Present in the following documents:
  • zgfazz-26-135.pdf
View BVdb publication page



Ultrasensitive analysis of genetic instability related to chemical exposure.

Journal Of Applied Genetics
Domoradzki, Tomasz T; Grochowski, Piotr P; Jaśkiewicz, Anna A; Pająk, Beata B
Publication Date: 2022-05

Variant appearance in text: EGFR: N771T
PubMed Link: 34967917
Variant Present in the following documents:
  • Main text
  • 13353_2021_Article_677.pdf
View BVdb publication page



DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties.

Oncogenesis
Little, A C AC; Sham, D D; Hristova, M M; Danyal, K K; Heppner, D E DE; Bauer, R A RA; Sipsey, L M LM; Habibovic, A A; van der Vliet, A A
Publication Date: 2016-10-03

Variant appearance in text: EGFR: N771T
PubMed Link: 27694834
Variant Present in the following documents:
  • Main text
  • oncsis201661a.pdf
View BVdb publication page



Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma.

Cancer Biology & Therapy
Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS
Publication Date: 2016

Variant appearance in text: EGFR: N771T
PubMed Link: 26785607
Variant Present in the following documents:
  • Main text
View BVdb publication page



Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer.

Oncotarget
Xu, Naiqing N; Fang, Wenfeng W; Mu, Libing L; Tang, Yanna Y; Gao, Lei L; Ren, Shengxiang S; Cao, Dengfeng D; Zhou, Lixin L; Zhang, Aiqun A; Liu, Deruo D; Zhou, Caicun C; Wong, Kwok-Kin KK; Yu, Lei L; Zhang, Li L; Chen, Liang L
Publication Date: 2016-01-26

Variant appearance in text: EGFR: N771T
PubMed Link: 26646697
Variant Present in the following documents:
  • oncotarget-07-3884-s001.pdf
View BVdb publication page



Kinome-wide decoding of network-attacking mutations rewiring cancer signaling.

Cell
Creixell, Pau P; Schoof, Erwin M EM; Simpson, Craig D CD; Longden, James J; Miller, Chad J CJ; Lou, Hua Jane HJ; Perryman, Lara L; Cox, Thomas R TR; Zivanovic, Nevena N; Palmeri, Antonio A; Wesolowska-Andersen, Agata A; Helmer-Citterich, Manuela M; Ferkinghoff-Borg, Jesper J; Itamochi, Hiroaki H; Bodenmiller, Bernd B; Erler, Janine T JT; Turk, Benjamin E BE; Linding, Rune R
Publication Date: 2015-09-24

Variant appearance in text: EGFR: N771T
PubMed Link: 26388441
Variant Present in the following documents:
  • mmc4.xlsx, sheet 1
View BVdb publication page



Epidermal growth factor receptor in non-small cell lung cancer.

Translational Lung Cancer Research
Prabhakar, Charles N CN
Publication Date: 2015-04

Variant appearance in text: EGFR: N771T
PubMed Link: 25870793
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular testing in lung cancer in the era of precision medicine.

Translational Lung Cancer Research
Popper, Helmut H HH; Ryska, Ales A; Tímár, József J; Olszewski, Wlodzimierz W
Publication Date: 2014-10

Variant appearance in text: EGFR: N771T
PubMed Link: 25806314
Variant Present in the following documents:
  • Main text
View BVdb publication page



Multiplex genomic profiling of non-small cell lung cancers from the LETS phase III trial of first-line S-1/carboplatin versus paclitaxel/carboplatin: results of a West Japan Oncology Group study.

Oncotarget
Okamoto, Isamu I; Sakai, Kazuko K; Morita, Satoshi S; Yoshioka, Hiroshige H; Kaneda, Hiroyasu H; Takeda, Koji K; Hirashima, Tomonori T; Kogure, Yoshihito Y; Kimura, Tatsuo T; Takahashi, Toshiaki T; Atagi, Shinji S; Seto, Takashi T; Sawa, Toshiyuki T; Yamamoto, Masashi M; Satouchi, Miyako M; Okuno, Motoyasu M; Nagase, Seisuke S; Takayama, Koichi K; Tomii, Keisuke K; Maeda, Tadashi T; Oizumi, Satoshi S; Fujii, Shinji S; Akashi, Yusaku Y; Nishino, Kazumi K; Ebi, Noriyuki N; Nakagawa, Kazuhiko K; Nakanishi, Yoichi Y; Nishio, Kazuto K
Publication Date: 2014-04-30

Variant appearance in text: EGFR: N771T
PubMed Link: 24810493
Variant Present in the following documents:
  • oncotarget-05-2293-s001.pdf
View BVdb publication page



Drug resistance and its significance for treatment decisions in non-small-cell lung cancer.

Current Oncology (Toronto, Ont.)
Tsvetkova, E E; Goss, G D GD
Publication Date: 2012-06

Variant appearance in text: EGFR: N771T
PubMed Link: 22787410
Variant Present in the following documents:
  • Main text
View BVdb publication page



Biomarkers of clinical benefit for anti-epidermal growth factor receptor agents in patients with non-small-cell lung cancer.

British Journal Of Cancer
Pallis, A G AG; Fennell, D A DA; Szutowicz, E E; Leighl, N B NB; Greillier, L L; Dziadziuszko, R R
Publication Date: 2011-06-28

Variant appearance in text: EGFR: N771T
PubMed Link: 21654681
Variant Present in the following documents:
  • Main text
  • bjc2011207a.pdf
View BVdb publication page



Mechanisms of drug resistance in kinases.

Expert Opinion On Investigational Drugs
Barouch-Bentov, Rina R; Sauer, Karsten K
Publication Date: 2011-02

Variant appearance in text: EGFR: N771T
PubMed Link: 21235428
Variant Present in the following documents:
  • Main text
View BVdb publication page



Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer.

Nature Reviews. Cancer
Pao, William W; Chmielecki, Juliann J
Publication Date: 2010-11

Variant appearance in text: EGFR: N771T
PubMed Link: 20966921
Variant Present in the following documents:
  • Main text
View BVdb publication page



A panel of high resolution melting (HRM) technology-based assays with direct sequencing possibility for effective mutation screening of EGFR and K-ras genes.

Cellular Oncology : The Official Journal Of The International Society For Cellular Oncology
Heideman, D A M DA; Thunnissen, F B FB; Doeleman, M M; Kramer, D D; Verheul, H M HM; Smit, E F EF; Postmus, P E PE; Meijer, C J L M CJ; Meijer, G A GA; Snijders, P J F PJ
Publication Date: 2009

Variant appearance in text: EGFR: N771T
PubMed Link: 19759413
Variant Present in the following documents:
  • ACP-2009-31-5-465850.pdf
View BVdb publication page



Activating and resistance mutations of EGFR in non-small-cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitors.

Oncogene
Gazdar, A F AF
Publication Date: 2009-08

Variant appearance in text: EGFR: N771T
PubMed Link: 19680293
Variant Present in the following documents:
  • Main text
View BVdb publication page