Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.
Rationale and design of a phase II trial of dacomitinib in advanced non-small cell lung cancer patients with uncommon epidermal growth factor receptor mutations: a prospective and single arm study (DANCE study).
Structure-based classification predicts drug response in EGFR-mutant NSCLC.
Nature
Robichaux, Jacqulyne P JP; Le, Xiuning X; Vijayan, R S K RSK; Hicks, J Kevin JK; Heeke, Simon S; Elamin, Yasir Y YY; Lin, Heather Y HY; Udagawa, Hibiki H; Skoulidis, Ferdinandos F; Tran, Hai H; Varghese, Susan S; He, Junqin J; Zhang, Fahao F; Nilsson, Monique B MB; Hu, Lemei L; Poteete, Alissa A; Rinsurongkawong, Waree W; Zhang, Xiaoshan X; Ren, Chenghui C; Liu, Xiaoke X; Hong, Lingzhi L; Zhang, Jianjun J; Diao, Lixia L; Madison, Russell R; Schrock, Alexa B AB; Saam, Jennifer J; Raymond, Victoria V; Fang, Bingliang B; Wang, Jing J; Ha, Min Jin MJ; Cross, Jason B JB; Gray, Jhanelle E JE; Heymach, John V JV
A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses.
Cancers
Koopman, Bart B; Cajiao Garcia, Betzabel N BN; Kuijpers, Chantal C H J CCHJ; Damhuis, Ronald A M RAM; van der Wekken, Anthonie J AJ; Groen, Harry J M HJM; Schuuring, Ed E; Willems, Stefan M SM; van Kempen, Léon C LC
Targeted Sequencing Facilitated Diagnosis of an Uncommon Patient Harboring Both Multiple Primary and Intrapulmonary Metastatic Lung Cancer: A Case Report.
Oncotargets And Therapy
Li, Hefei H; Dong, Shaoyong S; Zhang, Duo D; Guo, Zhimin Z; Li, Ce C; Xiang, Jianxing J; Zou, Xiao X; Yan, Li L; Sun, Ying Y; Li, Wei W
A Local and Low-Dose Chemotherapy/Autophagy-Enhancing Regimen Treatment Markedly Inhibited the Growth of Established Solid Tumors Through a Systemic Antitumor Immune Response.
The Pan-Cancer Landscape of Coamplification of the Tyrosine Kinases KIT, KDR, and PDGFRA.
The Oncologist
Disel, Umut U; Madison, Russell R; Abhishek, Kumar K; Chung, Jon H JH; Trabucco, Sally E SE; Matos, Asli O AO; Frampton, Garrett M GM; Albacker, Lee A LA; Reddy, Venkataprasanth V; Karadurmus, Nuri N; Benson, Adam A; Webster, Jennifer J; Paydas, Semra S; Cabanillas, Ruben R; Nangia, Chaitali C; Ozturk, M A MA; Millis, Sherri Z SZ; Pal, Sumanta K SK; Wilky, Breelyn B; Sokol, Ethan S ES; Gay, Laurie M LM; Soman, Salil S; Ganesan, Shridar S; Janeway, Katherine K; Stephens, Phil J PJ; Zhu, Viola W VW; Ou, Sai-Hong Ignatius SI; Lovly, Christine M CM; Gounder, Mrinal M; Schrock, Alexa B AB; Ross, Jeffrey S JS; Miller, Vincent A VA; Klempner, Samuel J SJ; Ali, Siraj M SM
Targeted mutation detection in breast cancer using MammaSeq™.
Breast Cancer Research : Bcr
Smith, Nicholas G NG; Gyanchandani, Rekha R; Shah, Osama S OS; Gurda, Grzegorz T GT; Lucas, Peter C PC; Hartmaier, Ryan J RJ; Brufsky, Adam M AM; Puhalla, Shannon S; Bahreini, Amir A; Kota, Karthik K; Wald, Abigail I AI; Nikiforov, Yuri E YE; Nikiforova, Marina N MN; Oesterreich, Steffi S; Lee, Adrian V AV
Better Progression-Free Survival in Elderly Patients with Stage IV Lung Adenocarcinoma Harboring Uncommon Epidermal Growth Factor Receptor Mutations Treated with the First-line Tyrosine Kinase Inhibitors.
Non-classic EGFR mutations in a cohort of Dutch EGFR-mutated NSCLC patients and outcomes following EGFR-TKI treatment.
British Journal Of Cancer
Kuiper, J L JL; Hashemi, S M S SM; Thunnissen, E E; Snijders, P J F PJ; Grünberg, K K; Bloemena, E E; Sie, D D; Postmus, P E PE; Heideman, D A M DA; Smit, E F EF
Correlations of EGFR mutations and increases in EGFR and HER2 copy number to gefitinib response in a retrospective analysis of lung cancer patients.
Bmc Cancer
Pugh, Trevor J TJ; Bebb, Gwyn G; Barclay, Lorena L; Sutcliffe, Margaret M; Fee, John J; Salski, Chris C; O'Connor, Robert R; Ho, Cheryl C; Murray, Nevin N; Melosky, Barbara B; English, John J; Vielkind, Jeurgen J; Horsman, Doug D; Laskin, Janessa J JJ; Marra, Marco A MA