EGFR c.2348C>T ;(p.T783I)

Variant ID: 7-55249050-C-T

NM_005228.3(EGFR):c.2348C>T;(p.T783I)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Rationale and design of a phase II trial of dacomitinib in advanced non-small cell lung cancer patients with uncommon epidermal growth factor receptor mutations: a prospective and single arm study (DANCE study).

Bmc Cancer
Zhang, Bo B; Shi, Chunlei C; Gao, Zhiqiang Z; Zhong, Hua H; Xiong, Liwen L; Gu, Aiqin A; Wang, Weimin W; Chu, Tianqing T; Zhang, Wei W; Wang, Huimin H; Zhang, Xueyan X; Zhong, Runbo R; Han, Baohui B
Publication Date: 2022-03-19

Variant appearance in text: EGFR: T783I
PubMed Link: 35305596
Variant Present in the following documents:
  • Main text
  • 12885_2022_Article_9409.pdf
View BVdb publication page



HER2 transmembrane domain mutation: comprehensive characteristics and real-world evidence of treatment response in Chinese lung adenocarcinoma.

Translational Lung Cancer Research
Jia, Ziqi Z; Xing, Jiahua J; Li, Ji J; Wang, Weiwei W; Wang, Yadong Y; Song, Yang Y; Yang, Xiaoying X; Xue, Jianchao J; Ye, Junyi J; Li, Bing B; Han-Zhang, Han H; Zhao, Jiaxing J; Zhang, Xiaochun X; Peng, Feng F; Chen, Fengxia F; Chen, Xueqin X; Lu, Yan Y; Ying, Shenpeng S; Wu, Dongping D; Zhang, Xinwei X; Ma, Caixia C; Lai, Lipeng L; Ma, Songling S; Liang, Dianjing D; Liu, Peng P; Li, Xiaoguang X; Liang, Naixin N; Li, Shanqing S
Publication Date: 2021-03

Variant appearance in text: EGFR: T783I
PubMed Link: 33889517
Variant Present in the following documents:
  • Main text
  • tlcr-10-03-1383.pdf
View BVdb publication page



ErBb Family Proteins in Cholangiocarcinoma and Clinical Implications.

Journal Of Clinical Medicine
Jin, Wook W
Publication Date: 2020-07-16

Variant appearance in text: EGFR: T783I
PubMed Link: 32708604
Variant Present in the following documents:
  • Main text
  • jcm-09-02255.pdf
View BVdb publication page



[A Review of EGFR-TKIs Therapy of Non-small Cell Lung Cancer
with Uncommon EGFR Mutations].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Du, Wenxing W; Wo, Yang Y; Lu, Tong T; Wang, Yuanyong Y; Jiao, Wenjie W
Publication Date: 2019-09-20

Variant appearance in text: EGFR: T783I
PubMed Link: 31526464
Variant Present in the following documents:
  • Main text
  • zgfazz-22-9-590.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: T783I
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
View BVdb publication page



Efficacy analysis of tyrosine kinase inhibitors on rare non-small cell lung cancer patients harboring complex EGFR mutations.

Scientific Reports
Peng, Liang L; Song, Zhi-Gang ZG; Jiao, Shun-Chang SC
Publication Date: 2014-08-18

Variant appearance in text: EGFR: T783I
PubMed Link: 25130612
Variant Present in the following documents:
  • Main text
  • srep06104.pdf
View BVdb publication page



The energy landscape analysis of cancer mutations in protein kinases.

Plos One
Dixit, Anshuman A; Verkhivker, Gennady M GM
Publication Date: 2011

Variant appearance in text: EGFR: T783I
PubMed Link: 21998754
Variant Present in the following documents:
View BVdb publication page



Epidemiology of doublet/multiplet mutations in lung cancers: evidence that a subset arises by chronocoordinate events.

Plos One
Chen, Zhenbin Z; Feng, Jinong J; Buzin, Carolyn H CH; Sommer, Steve S SS
Publication Date: 2008

Variant appearance in text: EGFR: T783I
PubMed Link: 19005564
Variant Present in the following documents:
  • Main text
  • pone.0003714.pdf
View BVdb publication page