EGFR c.2386G>A ;(p.G796S)

Variant ID: 7-55249088-G-A

NM_005228.3(EGFR):c.2386G>A;(p.G796S)

This variant was identified in 111 publications

View GRCh38 version.




Publications:


Making the Best Use of Available Weapons for the Inevitable Rivalry-Resistance to EGFR-TKIs.

Biomedicines
Li, Dongyu D; Wang, Jingnan J; Liu, Chengming C; Luo, Yuejun Y; Xu, Haiyan H; Wang, Yan Y; Sun, Nan N; He, Jie J
Publication Date: 2023-04-10

Variant appearance in text: EGFR: G796s
PubMed Link: 37189759
Variant Present in the following documents:
  • biomedicines-11-01141.pdf
View BVdb publication page



Challenges of EGFR-TKIs in NSCLC and the potential role of herbs and active compounds: From mechanism to clinical practice.

Frontiers In Pharmacology
Song, Xiaotong X; Cao, Luchang L; Ni, Baoyi B; Wang, Jia J; Qin, Xiaoyan X; Sun, Xiaoyue X; Xu, Bowen B; Wang, Xinmiao X; Li, Jie J
Publication Date: 2023

Variant appearance in text: EGFR: G796S
PubMed Link: 37089959
Variant Present in the following documents:
  • fphar-14-1090500.pdf
View BVdb publication page



Toward the next generation EGFR inhibitors: an overview of osimertinib resistance mediated by EGFR mutations in non-small cell lung cancer.

Cell Communication And Signaling : Ccs
Li, Yufeng Y; Mao, Tianyu T; Wang, Jing J; Zheng, Hongrui H; Hu, Ziyi Z; Cao, Pingping P; Yang, Suisui S; Zhu, Lingyun L; Guo, Shunyao S; Zhao, Xinfei X; Tian, Yue Y; Shen, Hua H; Lin, Fan F
Publication Date: 2023-04-11

Variant appearance in text: EGFR: G796S
PubMed Link: 37041601
Variant Present in the following documents:
  • Main text
  • 12964_2023_Article_1082.pdf
View BVdb publication page



Analysis of acquired resistance mechanisms to osimertinib in patients with EGFR-mutated advanced non-small cell lung cancer from the AURA3 trial.

Nature Communications
Chmielecki, Juliann J; Mok, Tony T; Wu, Yi-Long YL; Han, Ji-Youn JY; Ahn, Myung-Ju MJ; Ramalingam, Suresh S SS; John, Thomas T; Okamoto, Isamu I; Yang, James Chih-Hsin JC; Shepherd, Frances A FA; Bulusu, Krishna C KC; Laus, Gianluca G; Collins, Barbara B; Barrett, J Carl JC; Hartmaier, Ryan J RJ; Papadimitrakopoulou, Vassiliki V
Publication Date: 2023-02-27

Variant appearance in text: EGFR: G796S
PubMed Link: 36849516
Variant Present in the following documents:
  • Main text
  • 41467_2023_35962_MOESM2_ESM.xlsx, sheet 1
  • 41467_2023_Article_35962.pdf
View BVdb publication page



Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer.

Nature Communications
Chmielecki, Juliann J; Gray, Jhanelle E JE; Cheng, Ying Y; Ohe, Yuichiro Y; Imamura, Fumio F; Cho, Byoung Chul BC; Lin, Meng-Chih MC; Majem, Margarita M; Shah, Riyaz R; Rukazenkov, Yuri Y; Todd, Alexander A; Markovets, Aleksandra A; Barrett, J Carl JC; Hartmaier, Ryan J RJ; Ramalingam, Suresh S SS
Publication Date: 2023-02-27

Variant appearance in text: EGFR: G796S
PubMed Link: 36849494
Variant Present in the following documents:
  • 41467_2023_35961_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Response to Brigatinib Targeted Therapy in Non-Small Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Exon 19 Deletion, T790M, and cis-C797S Triple Mutations: A Case Report.

International Journal Of Molecular Sciences
Chen, Zi-Wei ZW; Lin, Gigin G; Shih, Hsuan-Jen HJ; Wu, Chiao-En CE
Publication Date: 2022-12-29

Variant appearance in text: EGFR: G796S
PubMed Link: 36614045
Variant Present in the following documents:
  • ijms-24-00602.pdf
View BVdb publication page



Afatinib plus osimertinib in the treatment of osimertinib-resistant non-small cell lung carcinoma: a phase I clinical trial.

Bmc Cancer
Miura, Satoru S; Koh, Yasuhiro Y; Azuma, Koichi K; Yoshioka, Hiroshige H; Koyama, Kenichi K; Teraoka, Shunsuke S; Ishii, Hidenobu H; Kibata, Kayoko K; Ozawa, Yuichi Y; Tokito, Takaaki T; Oyanagi, Jun J; Shimokawa, Toshio T; Kurata, Takayasu T; Yamamoto, Nobuyuki N; Tanaka, Hiroshi H
Publication Date: 2023-01-03

Variant appearance in text: EGFR: G796S
PubMed Link: 36597021
Variant Present in the following documents:
  • Main text
  • 12885_2022_Article_10467.pdf
View BVdb publication page



Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics
G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A
Publication Date: 2022

Variant appearance in text: rs754426793
PubMed Link: 36561320
Variant Present in the following documents:
  • Table2.xlsx, sheet 4
View BVdb publication page



Molecular pathways, resistance mechanisms and targeted interventions in non-small-cell lung cancer.

Molecular Biomedicine
Wang, Zixi Z; Xing, Yurou Y; Li, Bingjie B; Li, Xiaoyu X; Liu, Bin B; Wang, Yongsheng Y
Publication Date: 2022-12-12

Variant appearance in text: EGFR: G796S
PubMed Link: 36508072
Variant Present in the following documents:
  • Main text
  • 43556_2022_Article_107.pdf
View BVdb publication page



Therapeutic strategies for EGFR-mutated non-small cell lung cancer patients with osimertinib resistance.

Journal Of Hematology & Oncology
Fu, Kai K; Xie, Fachao F; Wang, Fang F; Fu, Liwu L
Publication Date: 2022-12-08

Variant appearance in text: EGFR: G796S
PubMed Link: 36482474
Variant Present in the following documents:
  • Main text
  • 13045_2022_Article_1391.pdf
View BVdb publication page



Calibration of computational tools for missense variant pathogenicity classification and ClinGen recommendations for PP3/BP4 criteria.

American Journal Of Human Genetics
Pejaver, Vikas V; Byrne, Alicia B AB; Feng, Bing-Jian BJ; Pagel, Kymberleigh A KA; Mooney, Sean D SD; Karchin, Rachel R; O'Donnell-Luria, Anne A; Harrison, Steven M SM; Tavtigian, Sean V SV; Greenblatt, Marc S MS; Biesecker, Leslie G LG; Radivojac, Predrag P; Brenner, Steven E SE; ,
Publication Date: 2022-12-01

Variant appearance in text: EGFR: G796S; rs754426793
PubMed Link: 36413997
Variant Present in the following documents:
  • mmc3.xlsx, sheet 1
View BVdb publication page



Aumolertinib challenge as an optional treatment in advanced non small-cell lung cancer after osimertinib failure with epidermal growth factor receptor-sensitive mutation: A case series.

Oncology Letters
Ding, Xinjing X; Ding, Jianghua J; Leng, Zhaohui Z; Song, Yun Y
Publication Date: 2022-11

Variant appearance in text: EGFR: G796s
PubMed Link: 36276494
Variant Present in the following documents:
  • ol-24-05-13520.pdf
View BVdb publication page



Protein tyrosine kinase inhibitor resistance in malignant tumors: molecular mechanisms and future perspective.

Signal Transduction And Targeted Therapy
Yang, Yang Y; Li, Shuo S; Wang, Yujiao Y; Zhao, Yi Y; Li, Qiu Q
Publication Date: 2022-09-17

Variant appearance in text: EGFR: G796S
PubMed Link: 36115852
Variant Present in the following documents:
  • Main text
View BVdb publication page



Monitoring Somatic Genetic Alterations in Circulating Cell-Free DNA/RNA of Patients with "Oncogene-Addicted" Advanced Lung Adenocarcinoma: A Real-World Clinical Study.

International Journal Of Molecular Sciences
Lupini, Laura L; Roncarati, Roberta R; Belluomini, Lorenzo L; Lancia, Federica F; Bassi, Cristian C; D'Abundo, Lucilla L; Michilli, Angelo A; Guerriero, Paola P; Fasano, Alessandra A; Tiberi, Elisa E; Salamone, Andrea A; Cosi, Donato Michele DM; Saccenti, Elena E; Tagliatti, Valentina V; Maestri, Iva I; Sabbioni, Silvia S; Volinia, Stefano S; Gafà, Roberta R; Lanza, Giovanni G; Frassoldati, Antonio A; Negrini, Massimo M
Publication Date: 2022-08-01

Variant appearance in text: EGFR: G796s
PubMed Link: 35955679
Variant Present in the following documents:
  • ijms-23-08546.pdf
View BVdb publication page



L718Q/V mutation in exon 18 of EGFR mediates resistance to osimertinib: clinical features and treatment.

Discover. Oncology
Li, Meihui M; Qin, Jing J; Xie, Fajun F; Gong, Lei L; Han, Na N; Lu, Hongyang H
Publication Date: 2022-08-09

Variant appearance in text: EGFR: G796S
PubMed Link: 35943592
Variant Present in the following documents:
  • 12672_2022_Article_537.pdf
View BVdb publication page



Resistance to TKIs in EGFR-Mutated Non-Small Cell Lung Cancer: From Mechanisms to New Therapeutic Strategies.

Cancers
Koulouris, Andreas A; Tsagkaris, Christos C; Corriero, Anna Chiara AC; Metro, Giulio G; Mountzios, Giannis G
Publication Date: 2022-07-08

Variant appearance in text: EGFR: G796S
PubMed Link: 35884398
Variant Present in the following documents:
  • Main text
  • cancers-14-03337.pdf
View BVdb publication page



AACR Project GENIE: 100,000 Cases and Beyond.

Cancer Discovery
Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,
Publication Date: 2022-09-02

Variant appearance in text: EGFR: G796S
PubMed Link: 35819403
Variant Present in the following documents:
  • cd-21-1547_supplementary_table_1_suppst1.xlsx, sheet 1
View BVdb publication page



The emerging landscape of EFGR tyrosine kinase inhibitors in lung adenocarcinoma-successes and challenges.

Journal Of Thoracic Disease
Oduah, Eziafa I EI; Lee, Chung-Shien CS; Seetharamu, Nagarashee N
Publication Date: 2022-06

Variant appearance in text: EGFR: G796S
PubMed Link: 35813761
Variant Present in the following documents:
  • Main text
  • jtd-14-06-1766.pdf
View BVdb publication page



RET kinase alterations in targeted cancer therapy.

Cancer Drug Resistance (Alhambra, Calif.)
Liu, Xuan X; Hu, Xueqing X; Shen, Tao T; Li, Qi Q; Mooers, Blaine H M BHM; Wu, Jie J
Publication Date: 2020

Variant appearance in text: EGFR: G796S
PubMed Link: 35582449
Variant Present in the following documents:
  • cdr-3-472.pdf
View BVdb publication page



Integrated proteomic analysis of low-grade gliomas reveals contributions of 1p-19q co-deletion to oligodendroglioma.

Acta Neuropathologica Communications
Wong, Derek D; Lee, Tae Hoon TH; Lum, Amy A; Tao, Valerie Lan VL; Yip, Stephen S
Publication Date: 2022-05-07

Variant appearance in text: EGFR: 2386G>A; Gly796Ser
PubMed Link: 35526077
Variant Present in the following documents:
  • 40478_2022_1372_MOESM18_ESM.xlsx, sheet 1
View BVdb publication page



Osimertinib-Centered Therapy Against Uncommon Epidermal Growth Factor Receptor-Mutated Non-Small-Cell Lung Cancer- A Mini Review.

Frontiers In Oncology
Song, Chengyang C; Yang, Xueying X
Publication Date: 2022

Variant appearance in text: EGFR: G796S
PubMed Link: 35494059
Variant Present in the following documents:
  • Main text
  • fonc-12-834585.pdf
View BVdb publication page



Preclinical Models for Acquired Resistance to Third-Generation EGFR Inhibitors in NSCLC: Functional Studies and Drug Combinations Used to Overcome Resistance.

Frontiers In Oncology
Mahfoudhi, Emna E; Ricordel, Charles C; Lecuyer, Gwendoline G; Mouric, Cécile C; Lena, Hervé H; Pedeux, Rémy R
Publication Date: 2022

Variant appearance in text: EGFR: G796S
PubMed Link: 35463360
Variant Present in the following documents:
  • Main text
  • fonc-12-853501.pdf
View BVdb publication page



Acquired Mechanisms of Resistance to Osimertinib-The Next Challenge.

Cancers
Ríos-Hoyo, Alejandro A; Moliner, Laura L; Arriola, Edurne E
Publication Date: 2022-04-12

Variant appearance in text: EGFR: G796S
PubMed Link: 35454838
Variant Present in the following documents:
  • Main text
  • cancers-14-01931.pdf
View BVdb publication page



Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.

Cancer Medicine
Liu, Binliang B; Yi, Zongbi Z; Guan, Yanfang Y; Ouyang, Quchang Q; Li, Chunxiao C; Guan, Xiuwen X; Lv, Dan D; Li, Lixi L; Zhai, Jingtong J; Qian, Haili H; Xu, Binghe B; Ma, Fei F; Zeng, Yixin Y
Publication Date: 2022-07

Variant appearance in text: EGFR: 2386G>A; G796S
PubMed Link: 35393784
Variant Present in the following documents:
  • CAM4-11-2767-s001.xlsx, sheet 1
View BVdb publication page



[Targeted Therapy and Mechanism of Drug Resistance in Non-small Cell Lung Cancer 
with Epidermal Growth Factor Receptor Gene Mutation].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Huang, Junxia J; Wang, Hong H
Publication Date: 2022-03-20

Variant appearance in text: EGFR: G796S
PubMed Link: 35340161
Variant Present in the following documents:
  • Main text
  • zgfazz-25-3-183.pdf
View BVdb publication page



The Role of TP53 Mutations in EGFR-Mutated Non-Small-Cell Lung Cancer: Clinical Significance and Implications for Therapy.

Cancers
Canale, Matteo M; Andrikou, Kalliopi K; Priano, Ilaria I; Cravero, Paola P; Pasini, Luigi L; Urbini, Milena M; Delmonte, Angelo A; Crinò, Lucio L; Bronte, Giuseppe G; Ulivi, Paola P
Publication Date: 2022-02-23

Variant appearance in text: EGFR: G796S
PubMed Link: 35267450
Variant Present in the following documents:
  • Main text
  • cancers-14-01143.pdf
View BVdb publication page



Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine
Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R
Publication Date: 2022-05

Variant appearance in text: EGFR: 2386G>A; Gly796Ser
PubMed Link: 35244186
Variant Present in the following documents:
  • Supplementary_Data3.xlsx, sheet 1
View BVdb publication page



EGFR exon 19 deletion switch and development of p.L792Q mutation as a new resistance mechanism to osimertinib: a case report and literature review.

Translational Cancer Research
Pisapia, Pasquale P; Rocco, Danilo D; Pepe, Francesco F; De Luca, Caterina C; Battiloro, Ciro C; Smeraglio, Riccardo R; Cieri, Miriam M; Bellevicine, Claudio C; Troncone, Giancarlo G; Malapelle, Umberto U
Publication Date: 2019-01

Variant appearance in text: EGFR: G796S
PubMed Link: 35117065
Variant Present in the following documents:
  • Main text
View BVdb publication page



Effective treatment of pulmonary adenocarcinoma harboring triple EGFR mutations of L858R, T790M, cis-G796s/cis-C797s by osimertinib, brigatinib, and bevacizumab combination therapy: A case report.

Respiratory Medicine Case Reports
Chang, Yuan Y; Liu, Shuang S; Jiang, Yanwen Y; Hua, Li L; Wen, Linfang L
Publication Date: 2022

Variant appearance in text: EGFR: G796s
PubMed Link: 35106279
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



EGFR-dependent mechanisms of resistance to osimertinib determined by ctDNA NGS analysis identify patients with better outcome.

Translational Lung Cancer Research
Vendrell, Julie A JA; Quantin, Xavier X; Aussel, Audrey A; Solassol, Isabelle I; Serre, Isabelle I; Solassol, Jérôme J
Publication Date: 2021-11

Variant appearance in text: EGFR: G796S
PubMed Link: 35004240
Variant Present in the following documents:
  • Main text
  • tlcr-10-11-4084.pdf
View BVdb publication page



Therapeutic advances in non-small cell lung cancer: Focus on clinical development of targeted therapy and immunotherapy.

Medcomm
Cheng, Yuan Y; Zhang, Tao T; Xu, Qing Q
Publication Date: 2021-12

Variant appearance in text: EGFR: G796S
PubMed Link: 34977873
Variant Present in the following documents:
  • Main text
  • MCO2-2-692.pdf
View BVdb publication page



Real-World Approach for Molecular Analysis of Acquired EGFR Tyrosine Kinase Inhibitor Resistance Mechanisms in NSCLC.

Jto Clinical And Research Reports
Hondelink, Liesbeth M LM; Jebbink, Merel M; von der Thüsen, Jan H JH; Cohen, Danielle D; Dubbink, Hendrikus J HJ; Paats, Marthe S MS; Dingemans, Anne-Marie C AC; de Langen, Adrianus J AJ; Boelens, Mirjam C MC; Smit, Egbert F EF; Postmus, Pieter E PE; van Wezel, Tom T; Monkhorst, Kim K
Publication Date: 2021-12

Variant appearance in text: EGFR: G796S
PubMed Link: 34849493
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Integrative Bioinformatics approaches to therapeutic gene target selection in various cancers for Nitroglycerin.

Scientific Reports
Chinnappan, Jayaprakash J; Ramu, Akilandeswari A; V, Vidhya Rajalakshmi VR; S, Akil Kavya AK
Publication Date: 2021-11-11

Variant appearance in text: EGFR: G796S
PubMed Link: 34764329
Variant Present in the following documents:
  • Main text
View BVdb publication page



Predictive and Prognostic Biomarkers for Lung Cancer Bone Metastasis and Their Therapeutic Value.

Frontiers In Oncology
Chai, Xupeng X; Yinwang, Eloy E; Wang, Zenan Z; Wang, Zhan Z; Xue, Yucheng Y; Li, Binghao B; Zhou, Hao H; Zhang, Wenkan W; Wang, Shengdong S; Zhang, Yongxing Y; Li, Hengyuan H; Mou, Haochen H; Sun, Lingling L; Qu, Hao H; Wang, Fangqian F; Zhang, Zengjie Z; Chen, Tao T; Ye, Zhaoming Z
Publication Date: 2021

Variant appearance in text: EGFR: G796S
PubMed Link: 34722241
Variant Present in the following documents:
  • fonc-11-692788.pdf
View BVdb publication page



Molecular Mechanism of EGFR-TKI Resistance in EGFR-Mutated Non-Small Cell Lung Cancer: Application to Biological Diagnostic and Monitoring.

Cancers
Reita, Damien D; Pabst, Lucile L; Pencreach, Erwan E; Guérin, Eric E; Dano, Laurent L; Rimelen, Valérie V; Voegeli, Anne-Claire AC; Vallat, Laurent L; Mascaux, Céline C; Beau-Faller, Michèle M
Publication Date: 2021-09-30

Variant appearance in text: EGFR: G796S
PubMed Link: 34638411
Variant Present in the following documents:
  • Main text
View BVdb publication page



Treating disease progression with osimertinib in EGFR-mutated non-small-cell lung cancer: novel targeted agents and combination strategies.

Esmo Open
Di Noia, V V; D'Aveni, A A; D'Argento, E E; Rossi, S S; Ghirardelli, P P; Bortolotti, L L; Vavassori, V V; Bria, E E; Ceresoli, G L GL
Publication Date: 2021-10-08

Variant appearance in text: EGFR: G796S
PubMed Link: 34634633
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: EGFR: G796S
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



High Incidence of C797S Mutation in Patients With Long Treatment History of EGFR Tyrosine Kinase Inhibitors Including Osimertinib.

Jto Clinical And Research Reports
Osoegawa, Atsushi A; Yamaguchi, Masafumi M; Nakamura, Tomomi T; Morinaga, Ryotaro R; Tanaka, Kentaro K; Kashiwabara, Kosuke K; Miura, Takashi T; Suetsugu, Takayuki T; Harada, Taishi T; Asoh, Tatsuma T; Taguchi, Kenichi K; Nabeshima, Kazuki K; Kishimoto, Junji J; Sakai, Kazuko K; Nishio, Kazuto K; Sugio, Kenji K
Publication Date: 2021-07

Variant appearance in text: EGFR: G796S
PubMed Link: 34590037
Variant Present in the following documents:
  • Main text
  • mmc1.xlsx, sheet 1
View BVdb publication page



Iterative Upgrading of Small Molecular Tyrosine Kinase Inhibitors for EGFR Mutation in NSCLC: Necessity and Perspective.

Pharmaceutics
Zhu, Jing J; Yang, Qian Q; Xu, Weiguo W
Publication Date: 2021-09-18

Variant appearance in text: EGFR: G796S
PubMed Link: 34575576
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mechanisms and management of 3rd‑generation EGFR‑TKI resistance in advanced non‑small cell lung cancer (Review).

International Journal Of Oncology
He, Jingyi J; Huang, Zhengrong Z; Han, Linzhi L; Gong, Yan Y; Xie, Conghua C
Publication Date: 2021-11

Variant appearance in text: EGFR: G796S
PubMed Link: 34558640
Variant Present in the following documents:
  • Main text
  • ijo-59-05-05270.pdf
View BVdb publication page



Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (Cambridge (Mass.))
Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J
Publication Date: 2021-05-28

Variant appearance in text: EGFR: G796S
PubMed Link: 34557754
Variant Present in the following documents:
  • Main text
View BVdb publication page



Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (New York, N.Y.)
Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J
Publication Date: 2021-05-28

Variant appearance in text: EGFR: G796S
PubMed Link: 34557754
Variant Present in the following documents:
  • Main text
View BVdb publication page



Structure-based classification predicts drug response in EGFR-mutant NSCLC.

Nature
Robichaux, Jacqulyne P JP; Le, Xiuning X; Vijayan, R S K RSK; Hicks, J Kevin JK; Heeke, Simon S; Elamin, Yasir Y YY; Lin, Heather Y HY; Udagawa, Hibiki H; Skoulidis, Ferdinandos F; Tran, Hai H; Varghese, Susan S; He, Junqin J; Zhang, Fahao F; Nilsson, Monique B MB; Hu, Lemei L; Poteete, Alissa A; Rinsurongkawong, Waree W; Zhang, Xiaoshan X; Ren, Chenghui C; Liu, Xiaoke X; Hong, Lingzhi L; Zhang, Jianjun J; Diao, Lixia L; Madison, Russell R; Schrock, Alexa B AB; Saam, Jennifer J; Raymond, Victoria V; Fang, Bingliang B; Wang, Jing J; Ha, Min Jin MJ; Cross, Jason B JB; Gray, Jhanelle E JE; Heymach, John V JV
Publication Date: 2021-09

Variant appearance in text: EGFR: 2386G>A; G796S
PubMed Link: 34526717
Variant Present in the following documents:
  • Main text
View BVdb publication page



A review of research progress on mechanisms and overcoming strategies of acquired osimertinib resistance.

Anti-Cancer Drugs
Qu, Fanjie F; Zhou, Yi Y; Yu, Weiwei W
Publication Date: 2021-09-13

Variant appearance in text: EGFR: G796S
PubMed Link: 34520433
Variant Present in the following documents:
  • Main text
  • acd-33-e76.pdf
View BVdb publication page



A review of research progress on mechanisms and overcoming strategies of acquired osimertinib resistance.

Anti-Cancer Drugs
Qu, Fanjie F; Zhou, Yi Y; Yu, Weiwei W
Publication Date: 2022-01-01

Variant appearance in text: EGFR: G796S
PubMed Link: 34520433
Variant Present in the following documents:
  • Main text
  • acd-33-e76.pdf
View BVdb publication page



NGS-Based ctDNA Profiling After the Resistance of Second-Line Osimertinib for Patient with EGFR-Mutated Pulmonary Adenocarcinoma.

Oncotargets And Therapy
Li, Dan D; Yang, DaFu D; Cui, SaiQiong S; Pan, Evenki E; Yang, Peng P; Dai, ZhaoXia Z
Publication Date: 2021

Variant appearance in text: EGFR: G796S
PubMed Link: 34321891
Variant Present in the following documents:
  • Main text
  • ott-14-4261.pdf
View BVdb publication page



Comparison of Resistance Spectra after First and Second Line Osimertinib Treatment Detected by Liquid Biopsy.

Cancers
Jóri, Balázs B; Schatz, Stefanie S; Kaller, Len L; Kah, Bettina B; Roeper, Julia J; Ramdani, Hayat O HO; Diehl, Linda L; Hoffknecht, Petra P; Grohé, Christian C; Griesinger, Frank F; Tiemann, Markus M; Heukamp, Lukas C LC; Falk, Markus M
Publication Date: 2021-06-08

Variant appearance in text: EGFR: G796S
PubMed Link: 34201252
Variant Present in the following documents:
  • Main text
  • cancers-13-02861.pdf
View BVdb publication page



Pan-cancer network disorders revealed by overall and local signaling entropy.

Journal Of Molecular Cell Biology
Feng, Li L; Sun, Yi-Di YD; Li, Chen C; Li, Yi-Xue YX; Chen, Luo-Nan LN; Zeng, Rong R
Publication Date: 2021-12-06

Variant appearance in text: EGFR: G796S
PubMed Link: 34097054
Variant Present in the following documents:
  • mjab031.pdf
View BVdb publication page



Epidermal Growth Factor Receptor Expression and Resistance Patterns to Targeted Therapy in Non-Small Cell Lung Cancer: A Review.

Cells
Karlsen, Emma-Anne EA; Kahler, Sam S; Tefay, Joan J; Joseph, Shannon R SR; Simpson, Fiona F
Publication Date: 2021-05-14

Variant appearance in text: EGFR: G796S
PubMed Link: 34069119
Variant Present in the following documents:
  • cells-10-01206.pdf
View BVdb publication page