EGFR c.2386_2388delinsTGA ;(p.G796*)

Variant ID: 7-55249088-GGC-TGA

NM_005228.3(EGFR):c.2386_2388delinsTGA;(p.G796*)

This variant was identified in 12 publications

View GRCh38 version.




Publications:


Toward the next generation EGFR inhibitors: an overview of osimertinib resistance mediated by EGFR mutations in non-small cell lung cancer.

Cell Communication And Signaling : Ccs
Li, Yufeng Y; Mao, Tianyu T; Wang, Jing J; Zheng, Hongrui H; Hu, Ziyi Z; Cao, Pingping P; Yang, Suisui S; Zhu, Lingyun L; Guo, Shunyao S; Zhao, Xinfei X; Tian, Yue Y; Shen, Hua H; Lin, Fan F
Publication Date: 2023-04-11

Variant appearance in text: EGFR: G796X
PubMed Link: 37041601
Variant Present in the following documents:
  • Main text
  • 12964_2023_Article_1082.pdf
View BVdb publication page



Overcoming CEP85L-ROS1, MKRN1-BRAF and MET amplification as rare, acquired resistance mutations to Osimertinib.

Frontiers In Oncology
Kian, Waleed W; Krayim, Bilal B; Alsana, Hadel H; Giles, Betsy B; Purim, Ofer O; Alguayn, Wafeek W; Alguayn, Farouq F; Peled, Nir N; Roisman, Laila C LC
Publication Date: 2023

Variant appearance in text: EGFR: G796X
PubMed Link: 36923435
Variant Present in the following documents:
  • Main text
  • fonc-13-1124949.pdf
View BVdb publication page



Recent progress in targeted therapy for non-small cell lung cancer.

Frontiers In Pharmacology
Xiao, Yanxia Y; Liu, Pu P; Wei, Jie J; Zhang, Xin X; Guo, Jun J; Lin, Yajun Y
Publication Date: 2023

Variant appearance in text: EGFR: G796X
PubMed Link: 36909198
Variant Present in the following documents:
  • Main text
  • fphar-14-1125547.pdf
View BVdb publication page



Therapeutic strategies for EGFR-mutated non-small cell lung cancer patients with osimertinib resistance.

Journal Of Hematology & Oncology
Fu, Kai K; Xie, Fachao F; Wang, Fang F; Fu, Liwu L
Publication Date: 2022-12-08

Variant appearance in text: EGFR: G796X
PubMed Link: 36482474
Variant Present in the following documents:
  • Main text
  • 13045_2022_Article_1391.pdf
View BVdb publication page



Acquired Mechanisms of Resistance to Osimertinib-The Next Challenge.

Cancers
Ríos-Hoyo, Alejandro A; Moliner, Laura L; Arriola, Edurne E
Publication Date: 2022-04-12

Variant appearance in text: EGFR: G796X
PubMed Link: 35454838
Variant Present in the following documents:
  • Main text
  • cancers-14-01931.pdf
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Utility of the Ba/F3 cell system for exploring on-target mechanisms of resistance to targeted therapies for lung cancer.

Cancer Science
Koga, Takamasa T; Suda, Kenichi K; Mitsudomi, Tetsuya T
Publication Date: 2022-03

Variant appearance in text: EGFR: G796X
PubMed Link: 34997674
Variant Present in the following documents:
  • Main text
  • CAS-113-815.pdf
View BVdb publication page



Hsa_circ_0005576 promotes osimertinib resistance through the miR-512-5p/IGF1R axis in lung adenocarcinoma cells.

Cancer Science
Liu, Suo S; Jiang, Zhibin Z; Xiao, Peng P; Li, Xiaozhi X; Chen, Yinji Y; Tang, Hao H; Chai, Yanfei Y; Liu, Yicai Y; Zhu, Zhao Z; Xie, Qianyi Q; He, Wei W; Ma, Yuchao Y; Jin, Longyu L; Feng, Wei W
Publication Date: 2021-10-27

Variant appearance in text: EGFR: G796X
PubMed Link: 34706132
Variant Present in the following documents:
  • Main text
  • CAS-113-79.pdf
View BVdb publication page



Hsa_circ_0005576 promotes osimertinib resistance through the miR-512-5p/IGF1R axis in lung adenocarcinoma cells.

Cancer Science
Liu, Suo S; Jiang, Zhibin Z; Xiao, Peng P; Li, Xiaozhi X; Chen, Yinji Y; Tang, Hao H; Chai, Yanfei Y; Liu, Yicai Y; Zhu, Zhao Z; Xie, Qianyi Q; He, Wei W; Ma, Yuchao Y; Jin, Longyu L; Feng, Wei W
Publication Date: 2022-01

Variant appearance in text: EGFR: G796X
PubMed Link: 34706132
Variant Present in the following documents:
  • Main text
  • CAS-113-79.pdf
View BVdb publication page



Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (New York, N.Y.)
Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J
Publication Date: 2021-05-28

Variant appearance in text: EGFR: G796X
PubMed Link: 34557754
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Acquired resistance to third-generation EGFR-TKIs and emerging next-generation EGFR inhibitors.

Innovation (Cambridge (Mass.))
Du, Xiaojing X; Yang, Biwei B; An, Quanlin Q; Assaraf, Yehuda G YG; Cao, Xin X; Xia, Jinglin J
Publication Date: 2021-05-28

Variant appearance in text: EGFR: G796X
PubMed Link: 34557754
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Toward structure-based drug design against the epidermal growth factor receptor (EGFR).

Drug Discovery Today
Haddad, Yazan Y; Remes, Marek M; Adam, Vojtech V; Heger, Zbynek Z
Publication Date: 2021-02

Variant appearance in text: EGFR: G796X
PubMed Link: 33075469
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Impact of concurrent genomic alterations in epidermal growth factor receptor (EGFR)-mutated lung cancer.

Journal Of Thoracic Disease
Gini, Beatrice B; Thomas, Nicholas N; Blakely, Collin M CM
Publication Date: 2020-05

Variant appearance in text: EGFR: G796X
PubMed Link: 32642201
Variant Present in the following documents:
  • Main text
  • jtd-12-05-2883.pdf
View BVdb publication page



Genetic alterations in epidermal growth factor receptor-tyrosine kinase inhibitor-naïve non-small cell lung carcinoma.

Oncology Letters
Yamaura, Takumi T; Muto, Satoshi S; Mine, Hayato H; Takagi, Hironori H; Watanabe, Masayuki M; Ozaki, Yuki Y; Inoue, Takuya T; Fukuhara, Mitsuro M; Okabe, Naoyuki N; Matsumura, Yuki Y; Hasegawa, Takeo T; Osugi, Jun J; Hoshino, Mika M; Higuchi, Mitsunori M; Shio, Yutaka Y; Suzuki, Hiroyuki H
Publication Date: 2020-06

Variant appearance in text: EGFR: G796X
PubMed Link: 32391110
Variant Present in the following documents:
  • Main text
View BVdb publication page