EGFR c.2450G>A ;(p.W817*)

Variant ID: 7-55249152-G-A

NM_005228.3(EGFR):c.2450G>A;(p.W817*)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Structural Insight and Development of EGFR Tyrosine Kinase Inhibitors.

Molecules (Basel, Switzerland)
Amelia, Tasia T; Kartasasmita, Rahmana Emran RE; Ohwada, Tomohiko T; Tjahjono, Daryono Hadi DH
Publication Date: 2022-01-26

Variant appearance in text: EGFR: W817X
PubMed Link: 35164092
Variant Present in the following documents:
  • Main text
  • molecules-27-00819.pdf
View BVdb publication page



Structural Insight and Development of EGFR Tyrosine Kinase Inhibitors.

Molecules (Basel, Switzerland)
Amelia, Tasia T; Kartasasmita, Rahmana Emran RE; Ohwada, Tomohiko T; Tjahjono, Daryono Hadi DH
Publication Date: 2022-01-26

Variant appearance in text: EGFR: W817X
PubMed Link: 35164092
Variant Present in the following documents:
  • Main text
  • molecules-27-00819.pdf
View BVdb publication page



Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast.

Communications Biology
Nagasawa, Satoi S; Kuze, Yuta Y; Maeda, Ichiro I; Kojima, Yasuyuki Y; Motoyoshi, Ai A; Onishi, Tatsuya T; Iwatani, Tsuguo T; Yokoe, Takamichi T; Koike, Junki J; Chosokabe, Motohiro M; Kubota, Manabu M; Seino, Hibiki H; Suzuki, Ayako A; Seki, Masahide M; Tsuchihara, Katsuya K; Inoue, Eisuke E; Tsugawa, Koichiro K; Ohta, Tomohiko T; Suzuki, Yutaka Y
Publication Date: 2021-04-01

Variant appearance in text: EGFR: W817X
PubMed Link: 33795819
Variant Present in the following documents:
  • 42003_2021_1959_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: W817*
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Variability in organ-specific EGFR mutational spectra in tumour epithelium and stroma may be the biological basis for differential responses to tyrosine kinase inhibitors.

British Journal Of Cancer
Weber, F F; Fukino, K K; Sawada, T T; Williams, N N; Sweet, K K; Brena, R M RM; Plass, C C; Caldes, T T; Mutter, G L GL; Villalona-Calero, M A MA; Eng, C C
Publication Date: 2005-05-23

Variant appearance in text: EGFR: W817X
PubMed Link: 15841079
Variant Present in the following documents:
  • Main text
  • 92-6602557a.pdf
View BVdb publication page