Pancreatic Cancer-Related Mutational Burden Is Not Increased in a Patient Cohort With Clinically Severe Chronic Pancreatitis.
Clinical And Translational Gastroenterology
Cowan, Robert W RW; Pratt, Erica D ED; Kang, Jin Muk JM; Zhao, Jun J; Wilhelm, Joshua J JJ; Abdulla, Muhamad M; Qiao, Edmund M EM; Brennan, Luke P LP; Ulintz, Peter J PJ; Bellin, Melena D MD; Rhim, Andrew D AD
A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses.
Cancers
Koopman, Bart B; Cajiao Garcia, Betzabel N BN; Kuijpers, Chantal C H J CCHJ; Damhuis, Ronald A M RAM; van der Wekken, Anthonie J AJ; Groen, Harry J M HJM; Schuuring, Ed E; Willems, Stefan M SM; van Kempen, Léon C LC
The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes.
British Journal Of Cancer
Salas-Benito, Diego D; Conde, Enrique E; Tamayo-Uria, Ibon I; Mancheño, Uxua U; Elizalde, Edurne E; Garcia-Ros, David D; Aramendia, Jose M JM; Muruzabal, Juan C JC; Alcaide, Julia J; Guillen-Grima, Francisco F; Minguez, Jose A JA; Amores-Tirado, Jose J; Gonzalez-Martin, Antonio A; Sarobe, Pablo P; Lasarte, Juan J JJ; Ponz-Sarvise, Mariano M; De Andrea, Carlos E CE; Hervas-Stubbs, Sandra S
Better Progression-Free Survival in Elderly Patients with Stage IV Lung Adenocarcinoma Harboring Uncommon Epidermal Growth Factor Receptor Mutations Treated with the First-line Tyrosine Kinase Inhibitors.
Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.
Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Frequency and clinical relevance of EGFR mutations and EML4-ALK translocations in octogenarians with non-small cell lung cancer.
Oncotargets And Therapy
Tufman, Amanda A; Kahnert, Kathrin K; Duell, Thomas T; Kauffmann-Guerrero, Diego D; Milger, Katrin K; Schneider, Christian C; Stump, Julia J; Syunyaeva, Zulfiya Z; Huber, Rudolf Maria RM; Reu, Simone S
Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.
Oncogene
Nickerson, M L ML; Witte, N N; Im, K M KM; Turan, S S; Owens, C C; Misner, K K; Tsang, S X SX; Cai, Z Z; Wu, S S; Dean, M M; Costello, J C JC; Theodorescu, D D
Mutation analysis of genes in the EGFR pathway in Head and Neck cancer patients: implications for anti-EGFR treatment response.
Bmc Research Notes
Boeckx, Carolien C; Weyn, Christine C; Vanden Bempt, Isabelle I; Deschoolmeester, Vanessa V; Wouters, An A; Specenier, Pol P; Van Laer, Carl C; Van den Weyngaert, Danielle D; Kockx, Mark M; Vermorken, Jan B JB; Peeters, Marc M; Pauwels, Patrick P; Lardon, Filip F; Baay, Marc M
Alterations in epidermal growth factor receptors 1 and 2 in esophageal squamous cell carcinomas.
Bmc Cancer
Gonzaga, Isabela Martins IM; Soares-Lima, Sheila Coelho SC; de Santos, Paulo Thiago Souza PT; Blanco, Tania Cristina Moita TC; de Reis, Bruno Souza Bianchi BS; Quintella, Danielle Carvalho DC; de Oliveira, Ivanir Martins IM; de Faria, Paulo Antonio Silvestre PA; Kruel, Cleber Dario Pinto CD; Andreollo, Nelson Adami NA; de Simão, Tatiana Almeida TA; Pinto, Luis Felipe Ribeiro LF
Lack of EGFR-activating mutations in European patients with triple-negative breast cancer could emphasise geographic and ethnic variations in breast cancer mutation profiles.
The human epidermal growth factor receptor (EGFR) gene in European patients with advanced colorectal cancer harbors infrequent mutations in its tyrosine kinase domain.
Bmc Medical Genetics
Metzger, Brigitte B; Chambeau, Laetitia L; Begon, Dominique Y DY; Faber, Carlo C; Kayser, Jacques J; Berchem, Guy G; Pauly, Marc M; Boniver, Jacques J; Delvenne, Philippe P; Dicato, Mario M; Wenner, Thomas T
Screening for EGFR Mutations in Patients with Head and Neck Cancer Treated with Gefitinib on a Compassionate-Use Program: A Hellenic Cooperative Oncology Group Study.
Journal Of Oncology
Murray, Samuel S; Bobos, Mattheos M; Angouridakis, Nikolaos N; Nikolaou, Angelos A; Linardou, Helena H; Razis, Evangelia E; Fountzilas, George G
Limited copy number-high resolution melting (LCN-HRM) enables the detection and identification by sequencing of low level mutations in cancer biopsies.
Polymorphisms in the epidermal growth factor receptor gene and the risk of primary lung cancer: a case-control study.
Bmc Cancer
Choi, Jin Eun JE; Park, Sun Ha SH; Kim, Kyung Mee KM; Lee, Won Kee WK; Kam, Sin S; Cha, Sung Ick SI; Kim, Chang Ho CH; Kang, Young Mo YM; Kim, Young-Chul YC; Han, Sung Beom SB; Jung, Tae Hoon TH; Park, Jae Yong JY