EGFR c.2525A>T ;(p.N842I)

Variant ID: 7-55259467-A-T

NM_005228.3(EGFR):c.2525A>T;(p.N842I)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Analytical and clinical validation of a custom 15-gene next-generation sequencing panel for the evaluation of circulating tumor DNA mutations in patients with advanced non-small-cell lung cancer.

Plos One
Chow, Yock Ping YP; Zainul Abidin, Norziha N; Kow, Ken Siong KS; Tho, Lye Mun LM; Wong, Chieh Lee CL
Publication Date: 2022

Variant appearance in text: EGFR: 2525A>T
PubMed Link: 36256645
Variant Present in the following documents:
  • pone.0276161.s002.xlsx, sheet 1
View BVdb publication page



Multilaboratory Assessment of a New Reference Material for Quality Assurance of Cell-Free Tumor DNA Measurements.

The Journal Of Molecular Diagnostics : Jmd
He, Hua-Jun HJ; Stein, Erica V EV; Konigshofer, Yves Y; Forbes, Thomas T; Tomson, Farol L FL; Garlick, Russell R; Yamada, Emiko E; Godfrey, Tony T; Abe, Toshiya T; Tamura, Koji K; Borges, Michael M; Goggins, Michael M; Elmore, Sandra S; Gulley, Margaret L ML; Larson, Jessica L JL; Ringel, Lando L; Haynes, Brian C BC; Karlovich, Chris C; Williams, P Mickey PM; Garnett, Aaron A; Ståhlberg, Anders A; Filges, Stefan S; Sorbara, Lynn L; Young, Mathew R MR; Srivastava, Sudhir S; Cole, Kenneth D KD
Publication Date: 2019-07

Variant appearance in text: EGFR: 2525A>T
PubMed Link: 31055023
Variant Present in the following documents:
  • Main text
View BVdb publication page



Olaparib is effective in combination with, and as maintenance therapy after, first-line endocrine therapy in prostate cancer cells.

Molecular Oncology
Feiersinger, Gertrud E GE; Trattnig, Kristina K; Leitner, Peter D PD; Guggenberger, Fabian F; Oberhuber, Alexander A; Peer, Sarah S; Hermann, Martin M; Skvortsova, Ira I; Vrbkova, Jana J; Bouchal, Jan J; Culig, Zoran Z; Santer, Frédéric R FR
Publication Date: 2018-04

Variant appearance in text: EGFR: 2525A>T; N842I
PubMed Link: 29465803
Variant Present in the following documents:
  • MOL2-12-561-s006.xlsx, sheet 7
View BVdb publication page



Erlotinib is effective in pancreatic cancer with epidermal growth factor receptor mutations: a randomized, open-label, prospective trial.

Oncotarget
Wang, Jack P JP; Wu, Chen-Yi CY; Yeh, Yi-Cheng YC; Shyr, Yi-Ming YM; Wu, Ying-Ying YY; Kuo, Chen-Yu CY; Hung, Yi-Ping YP; Chen, Ming-Huang MH; Lee, Wei-Ping WP; Luo, Jiing-Chyuan JC; Chao, Yee Y; Li, Chung-Pin CP
Publication Date: 2015-07-20

Variant appearance in text: EGFR: N842I
PubMed Link: 26046796
Variant Present in the following documents:
  • oncotarget-06-18162-s001.pdf
View BVdb publication page



HER family kinase domain mutations promote tumor progression and can predict response to treatment in human breast cancer.

Molecular Oncology
Boulbes, Delphine R DR; Arold, Stefan T ST; Chauhan, Gaurav B GB; Blachno, Korina V KV; Deng, Nanfu N; Chang, Wei-Chao WC; Jin, Quanri Q; Huang, Tzu-Hsuan TH; Hsu, Jung-Mao JM; Brady, Samuel W SW; Bartholomeusz, Chandra C; Ladbury, John E JE; Stone, Steve S; Yu, Dihua D; Hung, Mien-Chie MC; Esteva, Francisco J FJ
Publication Date: 2015-03

Variant appearance in text: EGFR: N842I
PubMed Link: 25435280
Variant Present in the following documents:
  • Main text
View BVdb publication page