Publications:

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Genomic Landscape of Primary Resistance to Osimertinib Among Hispanic Patients with EGFR-Mutant Non-Small Cell Lung Cancer (NSCLC): Results of an Observational Longitudinal Cohort Study.

Targeted Oncology

Chamorro, Diego F DF; Cardona, Andrés F AF; Rodríguez, July J; Ruiz-Patiño, Alejandro A; Arrieta, Oscar O; Moreno-Pérez, Darwin A DA; Rojas, Leonardo L; Zatarain-Barrón, Zyanya Lucia ZL; Ardila, Dora V DV; Viola, Lucia L; Recondo, Gonzalo G; Blaquier, Juan B JB; Martín, Claudio C; Raez, Luis L; Samtani, Suraj S; Ordóñez-Reyes, Camila C; Garcia-Robledo, Juan Esteban JE; Corrales, Luis L; Sotelo, Carolina C; Ricaurte, Luisa L; Cuello, Mauricio M; Mejía, Sergio S; Jaller, Elvira E; Vargas, Carlos C; Carranza, Hernán H; Otero, Jorge J; Archila, Pilar P; Bermudez, Maritza M; Gamez, Tatiana T; Russo, Alessandro A; Malapelle, Umberto U; de Miguel Perez, Diego D; de Lima, Vladmir C Cordeiro VCC; Freitas, Helano H; Saldahna, Erick E; Rolfo, Christian C; Rosell, Rafael R; ,

Publication Date: 2023-04-05

Variant appearance in text: EGFR: K846R

PubMed Link: 37017806

Variant Present in the following documents:

• Main text
• 11523_2023_Article_955.pdf

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Curcumin and Its Analogs in Non-Small Cell Lung Cancer Treatment: Challenges and Expectations.

Biomolecules

Tang, Chunyin C; Liu, Jieting J; Yang, Chunsong C; Ma, Jun J; Chen, Xuejiao X; Liu, Dongwen D; Zhou, Yao Y; Zhou, Wei W; Lin, Yunzhu Y; Yuan, Xiaohuan X

Publication Date: 2022-11-04

Variant appearance in text: EGFR: K846R

PubMed Link: 36358986

Variant Present in the following documents:

• Main text
• biomolecules-12-01636.pdf

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Effect of Curcumin on Attenuation of Liver Cirrhosis via Genes/Proteins and Pathways: A System Pharmacology Study.

Nutrients

Mahmoudi, Ali A; Atkin, Stephen L SL; Jamialahmadi, Tannaz T; Banach, Maciej M; Sahebkar, Amirhossein A

Publication Date: 2022-10-17

Variant appearance in text: EGFR: K846R

PubMed Link: 36297027

Variant Present in the following documents:

• nutrients-14-04344.pdf

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2537A>G; K846R

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

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Identification of novel bioactive molecules from garlic bulbs: A special effort to determine the anticancer potential against lung cancer with targeted drugs.

Saudi Journal Of Biological Sciences

Padmini, R R; Uma Maheshwari, V V; Saravanan, P P; Woo Lee, Keun K; Razia, M M; Alwahibi, Mona S MS; Ravindran, B B; Soliman Elshikh, Mohamed M; Ock Kim, Young Y; Kim, Hyungsuk H; Kim, Hak-Jae HJ

Publication Date: 2020-12

Variant appearance in text: EGFR: K846R

PubMed Link: 33304133

Variant Present in the following documents:

• main.pdf

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Risk factors of metachronous brain metastasis in patients with EGFR-mutated advanced non-small cell lung cancer.

Bmc Cancer

Ouyang, Wen W; Yu, Jing J; Zhou, Yan Y; Hu, Jing J; Huang, Zhao Z; Zhang, Junhong J; Xie, Conghua C

Publication Date: 2020-07-28

Variant appearance in text: EGFR: K846R

PubMed Link: 32723319

Variant Present in the following documents:

• Main text
• 12885_2020_Article_7202.pdf

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Serum Platelet-Derived Growth Factor Is Significantly Lower in Patients with Lung Cancer and Continued to Decrease After Platinum-Based Chemotherapy.

Oncotargets And Therapy

Ma, Rong R; Yang, Qing Q; Cao, Shengya S; Liu, Siwen S; Cao, Haixia H; Xu, Heng H; Wu, Jianzhong J; Feng, Jifeng J

Publication Date: 2020

Variant appearance in text: EGFR: K846R

PubMed Link: 32184623

Variant Present in the following documents:

• ott-13-1883.pdf

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Molecular designing, virtual screening and docking study of novel curcumin analogue as mutation (S769L and K846R) selective inhibitor for EGFR.

Saudi Journal Of Biological Sciences

Shaik, Noor Ahmad NA; Al-Kreathy, Huda M HM; Ajabnoor, Ghada M GM; Verma, Prashant Kumar PK; Banaganapalli, Babajan B

Publication Date: 2019-03

Variant appearance in text: EGFR: K846R

PubMed Link: 30899155

Variant Present in the following documents:

• Main text
• main.pdf

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Frequency, impact and a preclinical study of novel ERBB gene family mutations in HER2-positive breast cancer.

Therapeutic Advances In Medical Oncology

Elster, Naomi N; Toomey, Sinead S; Fan, Yue Y; Cremona, Mattia M; Morgan, Clare C; Weiner Gorzel, Karolina K; Bhreathnach, Una U; Milewska, Malgorzata M; Murphy, Madeline M; Madden, Stephen S; Naidoo, Jarushka J; Fay, Joanna J; Kay, Elaine E; Carr, Aoife A; Kennedy, Sean S; Furney, Simon S; Mezynski, Janusz J; Breathhnach, Oscar O; Morris, Patrick P; Grogan, Liam L; Hill, Arnold A; Kennedy, Susan S; Crown, John J; Gallagher, William W; Hennessy, Bryan B; Eustace, Alex A

Publication Date: 2018

Variant appearance in text: EGFR: K846R

PubMed Link: 30023006

Variant Present in the following documents:

• Main text
• Supplementary_material.pdf
• 10.1177_1758835918778297.pdf

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: EGFR: K846R

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 1
• pone.0196434.s001.xlsx, sheet 3
• pone.0196434.s001.xlsx, sheet 2

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Integrative annotation and knowledge discovery of kinase post-translational modifications and cancer-associated mutations through federated protein ontologies and resources.

Scientific Reports

Huang, Liang-Chin LC; Ross, Karen E KE; Baffi, Timothy R TR; Drabkin, Harold H; Kochut, Krzysztof J KJ; Ruan, Zheng Z; D'Eustachio, Peter P; McSkimming, Daniel D; Arighi, Cecilia C; Chen, Chuming C; Natale, Darren A DA; Smith, Cynthia C; Gaudet, Pascale P; Newton, Alexandra C AC; Wu, Cathy C; Kannan, Natarajan N

Publication Date: 2018-04-25

Variant appearance in text: EGFR: K846R

PubMed Link: 29695735

Variant Present in the following documents:

• 41598_2018_24457_MOESM1_ESM.pdf

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: ERBB: 2537A>G

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

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Epidermal growth factor receptor in non-small cell lung cancer.

Translational Lung Cancer Research

Prabhakar, Charles N CN

Publication Date: 2015-04

Variant appearance in text: EGFR: K846R

PubMed Link: 25870793

Variant Present in the following documents:

• Main text

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The energy landscape analysis of cancer mutations in protein kinases.

Plos One

Dixit, Anshuman A; Verkhivker, Gennady M GM

Publication Date: 2011

Variant appearance in text: EGFR: K846R

PubMed Link: 21998754

Variant Present in the following documents:

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Mechanisms of drug resistance in kinases.

Expert Opinion On Investigational Drugs

Barouch-Bentov, Rina R; Sauer, Karsten K

Publication Date: 2011-02

Variant appearance in text: EGFR: K846R

PubMed Link: 21235428

Variant Present in the following documents:

• Main text

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