Publications:

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Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: T847A

PubMed Link: 35304574

Variant Present in the following documents:

• 41388_2022_Article_2263.pdf

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Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer.

Nature Communications

Vandekerkhove, Gillian G; Lavoie, Jean-Michel JM; Annala, Matti M; Murtha, Andrew J AJ; Sundahl, Nora N; Walz, Simon S; Sano, Takeshi T; Taavitsainen, Sinja S; Ritch, Elie E; Fazli, Ladan L; Hurtado-Coll, Antonio A; Wang, Gang G; Nykter, Matti M; Black, Peter C PC; Todenhöfer, Tilman T; Ost, Piet P; Gibb, Ewan A EA; Chi, Kim N KN; Eigl, Bernhard J BJ; Wyatt, Alexander W AW

Publication Date: 2021-01-08

Variant appearance in text: EGFR: T847A

PubMed Link: 33420073

Variant Present in the following documents:

• 41467_2020_20493_MOESM3_ESM.xlsx, sheet 4

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[Research Progress in Consistency of Driver Gene Status between Primary and Corresponding Metastatic Lesions in Non-small Cell Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Zhou, Bing B; Xiong, Jianping J

Publication Date: 2020-03-20

Variant appearance in text: EGFR: T847A

PubMed Link: 32102137

Variant Present in the following documents:

• Main text
• zgfazz-23-3-196.pdf

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Genetic heterogeneity in hepatocellular carcinoma and paired bone metastasis revealed by next-generation sequencing.

International Journal Of Clinical And Experimental Pathology

Jin, Ketao K; Lan, Huanrong H; Wang, Xuanwei X; Lv, Jieqing J

Publication Date: 2017

Variant appearance in text: EGFR: 2539A>G; Thr847Ala

PubMed Link: 31966388

Variant Present in the following documents:

• Main text

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: EGFR: T847A

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 1
• pone.0196434.s001.xlsx, sheet 3
• pone.0196434.s001.xlsx, sheet 2

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EGFR mutational status in a large series of Caucasian European NSCLC patients: data from daily practice.

British Journal Of Cancer

Gahr, S S; Stoehr, R R; Geissinger, E E; Ficker, J H JH; Brueckl, W M WM; Gschwendtner, A A; Gattenloehner, S S; Fuchs, F S FS; Schulz, C C; Rieker, R J RJ; Hartmann, A A; Ruemmele, P P; Dietmaier, W W

Publication Date: 2013-10-01

Variant appearance in text: EGFR: T847A

PubMed Link: 24002608

Variant Present in the following documents:

• Main text
• bjc2013511a.pdf

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Assessment of computational methods for predicting the effects of missense mutations in human cancers.

Bmc Genomics

Gnad, Florian F; Baucom, Albion A; Mukhyala, Kiran K; Manning, Gerard G; Zhang, Zemin Z

Publication Date: 2013

Variant appearance in text: EGFR: T847A

PubMed Link: 23819521

Variant Present in the following documents:

• 1471-2164-14-S3-S7-S1.xlsx, sheet 2
• 1471-2164-14-S3-S7-S1.xlsx, sheet 1

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DNA-Mutation Inventory to Refine and Enhance Cancer Treatment (DIRECT): a catalog of clinically relevant cancer mutations to enable genome-directed anticancer therapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Yeh, Paul P; Chen, Heidi H; Andrews, Jenny J; Naser, Riyad R; Pao, William W; Horn, Leora L

Publication Date: 2013-04-01

Variant appearance in text: EGFR: T847A

PubMed Link: 23344264

Variant Present in the following documents:

• Main text

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Comparison of EGFR and K-RAS gene status between primary tumours and corresponding metastases in NSCLC.

British Journal Of Cancer

Kalikaki, A A; Koutsopoulos, A A; Trypaki, M M; Souglakos, J J; Stathopoulos, E E; Georgoulias, V V; Mavroudis, D D; Voutsina, A A

Publication Date: 2008-09-16

Variant appearance in text: EGFR: T847A

PubMed Link: 19238633

Variant Present in the following documents:

• Main text

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'Classical' but not 'other' mutations of EGFR kinase domain are associated with clinical outcome in gefitinib-treated patients with non-small cell lung cancer.

British Journal Of Cancer

Pallis, A G AG; Voutsina, A A; Kalikaki, Ar A; Souglakos, J J; Briasoulis, E E; Murray, S S; Koutsopoulos, A A; Tripaki, M M; Stathopoulos, E E; Mavroudis, D D; Georgoulias, V V

Publication Date: 2007-12-03

Variant appearance in text: EGFR: T847A

PubMed Link: 18000506

Variant Present in the following documents:

• Main text
• 6604068a.pdf

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