Publications:

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Overview on Therapeutic Options in Uncommon EGFR Mutant Non-Small Cell Lung Cancer (NSCLC): New Lights for an Unmet Medical Need.

International Journal Of Molecular Sciences

Pretelli, Giulia G; Spagnolo, Calogera Claudia CC; Ciappina, Giuliana G; Santarpia, Mariacarmela M; Pasello, Giulia G

Publication Date: 2023-05-17

Variant appearance in text: EGFR: P848L

PubMed Link: 37240224

Variant Present in the following documents:

• Main text
• ijms-24-08878.pdf

View BVdb publication page

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Optimal therapy for concomitant EGFR and TP53 mutated non-small cell lung cancer: a real-world study.

Bmc Cancer

Sun, Haiyan H; Ren, Peng P; Chen, Yongzi Y; Lan, Lan L; Yan, Zhuchen Z; Yang, Yinli Y; Wang, Bin B; Wang, Cong C; Li, Yanwei Y; Li, Ling L; Zhang, Yu Y; Li, Yanyang Y; Wang, Zuolin Z; Pan, Zhanyu Z; Jiang, Zhansheng Z

Publication Date: 2023-03-02

Variant appearance in text: EGFR: P848L

PubMed Link: 36864384

Variant Present in the following documents:

• Main text
• 12885_2023_Article_10637.pdf

View BVdb publication page

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Clinical outcome of Brazilian patients with non-small cell lung cancer in early stage harboring rare mutations in epidermal growth factor receptor.

Brazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas

Machado-Rugolo, J J; Baldavira, C M CM; Prieto, T G TG; Olivieri, E H R EHR; Fabro, A T AT; Rainho, C A CA; Castelli, E C EC; Ribolla, P E M PEM; Ab'Saber, A M AM; Takagaki, T T; Nagai, M A MA; Capelozzi, V L VL

Publication Date: 2023

Variant appearance in text: EGFR: 2543C>T; Pro848Leu; rs148934350

PubMed Link: 36629526

Variant Present in the following documents:

• Main text
• 1414-431X-bjmbr-55-e12409.pdf

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: rs148934350

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 4

View BVdb publication page

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: EGFR: P848L

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non-Small Cell Lung Cancer.

Cancer Research

Woo, Xing Yi XY; Srivastava, Anuj A; Mack, Philip C PC; Graber, Joel H JH; Sanderson, Brian J BJ; Lloyd, Michael W MW; Chen, Mandy M; Domanskyi, Sergii S; Gandour-Edwards, Regina R; Tsai, Rebekah A RA; Keck, James J; Cheng, Mingshan M; Bundy, Margaret M; Jocoy, Emily L EL; Riess, Jonathan W JW; Holland, William W; Grubb, Stephen C SC; Peterson, James G JG; Stafford, Grace A GA; Paisie, Carolyn C; Neuhauser, Steven B SB; Karuturi, R Krishna Murthy RKM; George, Joshy J; Simons, Allen K AK; Chavaree, Margaret M; Tepper, Clifford G CG; Goodwin, Neal N; Airhart, Susan D SD; Lara, Primo N PN; Openshaw, Thomas H TH; Liu, Edison T ET; Gandara, David R DR; Bult, Carol J CJ

Publication Date: 2022-11-15

Variant appearance in text: EGFR: P848L

PubMed Link: 36069866

Variant Present in the following documents:

• 4126.pdf

View BVdb publication page

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: EGFR: P848L

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

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Integrative analysis prioritised oxytocin-related biomarkers associated with the aetiology of autism spectrum disorder.

Ebiomedicine

Wang, Tao T; Zhao, Tingting T; Liu, Liqiu L; Teng, Huajing H; Fan, Tianda T; Li, Yi Y; Wang, Yan Y; Li, Jinchen J; Xia, Kun K; Sun, Zhongsheng Z

Publication Date: 2022-07

Variant appearance in text: EGFR: 2543C>T; P848L; rs148934350

PubMed Link: 35665681

Variant Present in the following documents:

• mmc26.xlsx, sheet 1

View BVdb publication page

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Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: P848L

PubMed Link: 35304574

Variant Present in the following documents:

• 41388_2022_Article_2263.pdf

View BVdb publication page

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Desmoid fibromatosis in the pharyngeal wall: A case report and literature review.

Clinical Case Reports

Geisenhainer, Katharina K; Klenke, Daniela D; Moser, Norman N; Kurbad, Oliver O; Bremmer, Felix F; Kauffmann, Philipp P; Schliephake, Henning H; Brockmeyer, Phillipp P

Publication Date: 2022-01

Variant appearance in text: EGFR: P848L

PubMed Link: 35028152

Variant Present in the following documents:

• Main text
• CCR3-10-e05268.pdf

View BVdb publication page

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Circulating Cell-Free DNA-Based Comprehensive Molecular Analysis of Biliary Tract Cancers Using Next-Generation Sequencing.

Cancers

Csoma, Szilvia Lilla SL; Bedekovics, Judit J; Veres, Gergő G; Árokszállási, Anita A; András, Csilla C; Méhes, Gábor G; Mokánszki, Attila A

Publication Date: 2022-01-04

Variant appearance in text: EGFR: 2543C>T; Pro848Leu

PubMed Link: 35008396

Variant Present in the following documents:

• Main text
• cancers-14-00233.pdf

View BVdb publication page

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Circulating Cell-Free DNA-Based Comprehensive Molecular Analysis of Biliary Tract Cancers Using Next-Generation Sequencing.

Cancers

Csoma, Szilvia Lilla SL; Bedekovics, Judit J; Veres, Gergő G; Árokszállási, Anita A; András, Csilla C; Méhes, Gábor G; Mokánszki, Attila A

Publication Date: 2022-01-04

Variant appearance in text: EGFR: 2543C>T; Pro848Leu

PubMed Link: 35008396

Variant Present in the following documents:

• Main text
• cancers-14-00233.pdf

View BVdb publication page

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Systematic population-based identification of NTRK and RET fusion-positive thyroid cancers.

European Thyroid Journal

Eszlinger, Markus M; Stewardson, Paul P; McIntyre, John B JB; Box, Adrian A; Khalil, Moosa M; Hyrcza, Martin M; Koro, Konstantin K; Ruether, Dean D; Wu, Jiahui J; Paschke, Ralf R

Publication Date: 2022-01-27

Variant appearance in text: EGFR: P848L

PubMed Link: 34981751

Variant Present in the following documents:

• Main text
• ETJ-21-0061.pdf

View BVdb publication page

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Identification of the Unique Clinical and Genetic Features of Chinese Lung Cancer Patients With EGFR Germline Mutations in a Large-Scale Retrospective Study.

Frontiers In Oncology

Lin, Xinqing X; Peng, Muyun M; Chen, Quanfang Q; Yuan, Mingming M; Chen, Rongrong R; Deng, Haiyi H; Deng, Jiaxi J; Liu, Ouqi O; Weng, Yuqing Y; Chen, Mingjiu M; Zhou, Chengzhi C

Publication Date: 2021

Variant appearance in text: EGFR: P848L

PubMed Link: 34869019

Variant Present in the following documents:

• Main text
• fonc-11-774156.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: EGFR: P848L

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses.

Cancers

Koopman, Bart B; Cajiao Garcia, Betzabel N BN; Kuijpers, Chantal C H J CCHJ; Damhuis, Ronald A M RAM; van der Wekken, Anthonie J AJ; Groen, Harry J M HJM; Schuuring, Ed E; Willems, Stefan M SM; van Kempen, Léon C LC

Publication Date: 2021-07-20

Variant appearance in text: EGFR: P848L

PubMed Link: 34298851

Variant Present in the following documents:

• Main text
• cancers-13-03641.pdf

View BVdb publication page

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Comparison of two targeted ultra-deep sequencing technologies for analysis of plasma circulating tumour DNA in endocrine-therapy-resistant breast cancer patients.

Breast Cancer Research And Treatment

Nteliopoulos, Georgios G; Page, Karen K; Hills, Allison A; Howarth, Karen K; Emmett, Warren W; Green, Emma E; Martinson, Luke J LJ; Fernadez-Garcia, Daniel D; Hastings, Robert R; Guttery, David S DS; Kenny, Laura L; Stebbing, Justin J; Cleator, Susan S; Rehman, Farah F; Gleason, Kelly L T KLT; Sanela, Andrijac A; Ion, Charlotte C; Rushton, Amelia J AJ; Rosenfeld, Nitzan N; Coombes, R Charles RC; Shaw, Jacqueline A JA

Publication Date: 2021-07

Variant appearance in text: EGFR: P848L

PubMed Link: 34097174

Variant Present in the following documents:

• 10549_2021_6220_MOESM2_ESM.xlsx, sheet 2
• 10549_2021_6220_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients.

Oncotarget

Barakeh, Duna H DH; Aljelaify, Rasha R; Bashawri, Yara Y; Almutairi, Amal A; Alqubaishi, Fatimah F; Alnamnakani, Mohammed M; Almubarak, Latifa L; Al Naeem, Abdulrahman A; Almushawah, Fatema F; Alrashed, May M; Abedalthagafi, Malak M

Publication Date: 2021-03-30

Variant appearance in text: EGFR: 2543C>T; P848L

PubMed Link: 33868589

Variant Present in the following documents:

• oncotarget-12-686-s002.xlsx, sheet 1

View BVdb publication page

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Combined assay of Circulating Tumor DNA and Protein Biomarkers for early noninvasive detection and prognosis of Non-Small Cell Lung Cancer.

Journal Of Cancer

Yin, Jian-Xin JX; Hu, Wen-Wei WW; Gu, Hua H; Fang, Jian-Min JM

Publication Date: 2021

Variant appearance in text: EGFR: P848L

PubMed Link: 33442424

Variant Present in the following documents:

• jcav12p1258s2.xlsx, sheet 4

View BVdb publication page

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Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups.

Bmc Medical Genomics

Miller, Eirwen M EM; Patterson, Nicole E NE; Gressel, Gregory M GM; Karabakhtsian, Rouzan G RG; Bejerano-Sagie, Michal M; Ravi, Nivedita N; Maslov, Alexander A; Quispe-Tintaya, Wilber W; Wang, Tao T; Lin, Juan J; Smith, Harriet O HO; Goldberg, Gary L GL; Kuo, Dennis Y S DYS; Montagna, Cristina C

Publication Date: 2020-11-30

Variant appearance in text: EGFR: P848L

PubMed Link: 33256706

Variant Present in the following documents:

• 12920_2020_824_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports

Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA

Publication Date: 2020-09-21

Variant appearance in text: EGFR: P848L

PubMed Link: 32958805

Variant Present in the following documents:

• 41598_2020_72404_MOESM2_ESM.xlsx, sheet 3

View BVdb publication page

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Novel EGFR V834L Germline Mutation Associated With Familial Lung Adenocarcinoma.

Jco Precision Oncology

van der Leest, Cor C; Wagner, Anja A; Pedrosa, Rute M RM; Aerts, Joachim G JG; Dinjens, Winand N M WNM; Dubbink, Hendrikus J HJ

Publication Date: 2018

Variant appearance in text: EGFR: P848L

PubMed Link: 32913987

Variant Present in the following documents:

• Main text
• PO.17.00266.pdf

View BVdb publication page

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Patients with advanced non-small cell lung cancer with EGFR mutations in addition to complex mutations treated with osimertinib have a poor clinical outcome: A real-world data analysis.

Oncology Letters

Chang, Nijia N; Duan, Jingjing J; Wang, Lingxiong L; Dong, Zhouhuan Z; Liu, Zhefeng Z

Publication Date: 2020-09

Variant appearance in text: EGFR: P848L

PubMed Link: 32782544

Variant Present in the following documents:

• Main text
• ol-20-03-2266.pdf

View BVdb publication page

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Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine

Li, Jiaping J; Jiang, Wei W; Wei, Jinwang J; Zhang, Jianwei J; Cai, Linbo L; Luo, Minjie M; Wang, Zhan Z; Sun, Wending W; Wang, Shengzhou S; Wang, Chen C; Dai, Chun C; Liu, Jun J; Wang, Guan G; Wang, Jiping J; Xu, Qiang Q; Deng, Yanhong Y

Publication Date: 2020-08-01

Variant appearance in text: EGFR: 2543C>T; P848L

PubMed Link: 32738923

Variant Present in the following documents:

• 12967_2020_2449_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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The contribution of hereditary cancer-related germline mutations to lung cancer susceptibility.

Translational Lung Cancer Research

Liu, Mengyuan M; Liu, Xinyi X; Suo, Peisu P; Gong, Yuan Y; Qu, Baolin B; Peng, Xiumei X; Xiao, Wenhua W; Li, Yuemin Y; Chen, Yan Y; Zeng, Zhen Z; Lu, Yinying Y; Huang, Tanxiao T; Zhao, Yingshen Y; Liu, Ming M; Li, Lifeng L; Chen, Yaru Y; Zhou, Yanqing Y; Liu, Guifeng G; Yao, Jianfei J; Chen, Shifu S; Song, Lele L

Publication Date: 2020-06

Variant appearance in text: EGFR: P848L

PubMed Link: 32676327

Variant Present in the following documents:

• Main text
• tlcr-09-03-646.pdf

View BVdb publication page

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Mutation and drug-specific intracellular accumulation of EGFR predict clinical responses to tyrosine kinase inhibitors.

Ebiomedicine

de Wit, Maurice M; Gao, Ya Y; Mercieca, Darlene D; de Heer, Iris I; Valkenburg, Bart B; van Royen, Martin E ME; Aerts, Joachim J; Sillevis Smitt, Peter P; French, Pim P

Publication Date: 2020-06

Variant appearance in text: EGFR: P848L

PubMed Link: 32512509

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Early assessment of KRAS mutation in cfDNA correlates with risk of progression and death in advanced non-small-cell lung cancer.

British Journal Of Cancer

Zulato, Elisabetta E; Attili, Ilaria I; Pavan, Alberto A; Nardo, Giorgia G; Del Bianco, Paola P; Boscolo Bragadin, Andrea A; Verza, Martina M; Pasqualini, Lorenza L; Pasello, Giulia G; Fassan, Matteo M; Calabrese, Fiorella F; Guarneri, Valentina V; Amadori, Alberto A; Conte, PierFranco P; Indraccolo, Stefano S; Bonanno, Laura L

Publication Date: 2020-07

Variant appearance in text: EGFR: P848L

PubMed Link: 32376889

Variant Present in the following documents:

• 41416_2020_833_MOESM1_ESM.pdf

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: EGFR: P848L

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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Novel pathogenic alterations in pediatric and adult desmoid-type fibromatosis - A systematic analysis of 204 cases.

Scientific Reports

Trautmann, Marcel M; Rehkämper, Jan J; Gevensleben, Heidrun H; Becker, Jessica J; Wardelmann, Eva E; Hartmann, Wolfgang W; Grünewald, Inga I; Huss, Sebastian S

Publication Date: 2020-02-25

Variant appearance in text: EGFR: P848L

PubMed Link: 32099073

Variant Present in the following documents:

• Main text
• 41598_2020_Article_60237.pdf
• 41598_2020_60237_MOESM1_ESM.pdf

View BVdb publication page

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Genetic alterations of malignant pleural mesothelioma: association with tumor heterogeneity and overall survival.

Molecular Oncology

Quetel, Lisa L; Meiller, Clément C; Assié, Jean-Baptiste JB; Blum, Yuna Y; Imbeaud, Sandrine S; Montagne, François F; Tranchant, Robin R; de Wolf, Julien J; Caruso, Stefano S; Copin, Marie-Christine MC; Hofman, Véronique V; Gibault, Laure L; Badoual, Cécile C; Pintilie, Ecaterina E; Hofman, Paul P; Monnet, Isabelle I; Scherpereel, Arnaud A; Le Pimpec-Barthes, Françoise F; Zucman-Rossi, Jessica J; Jaurand, Marie-Claude MC; Jean, Didier D

Publication Date: 2020-06

Variant appearance in text: EGFR: P848L

PubMed Link: 32083805

Variant Present in the following documents:

• MOL2-14-1207-s005.xlsx, sheet 1

View BVdb publication page

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Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology

Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M

Publication Date: 2020-01-07

Variant appearance in text: EGFR: 2543C>T; P848L

PubMed Link: 31925297

Variant Present in the following documents:

• 42003_2019_736_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Osimertinib as treatment for EGFR exon 20 insertion-positive lung adenocarcinoma.

Excli Journal

Murano, Chihiro C; Igarashi, Akira A; Yamauchi, Keiko K; Inoue, Sumito S; Watanabe, Masafumi M

Publication Date: 2019

Variant appearance in text: EGFR: P848L

PubMed Link: 31645848

Variant Present in the following documents:

• Main text
• EXCLI-18-893.pdf

View BVdb publication page

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Mutation profiling of cancer drivers in Brazilian colorectal cancer.

Scientific Reports

Dos Santos, Wellington W; Sobanski, Thais T; de Carvalho, Ana Carolina AC; Evangelista, Adriane Feijó AF; Matsushita, Marcus M; Berardinelli, Gustavo Nóriz GN; de Oliveira, Marco Antonio MA; Reis, Rui Manuel RM; Guimarães, Denise Peixoto DP

Publication Date: 2019-09-23

Variant appearance in text: EGFR: P848L

PubMed Link: 31548566

Variant Present in the following documents:

• Main text

View BVdb publication page

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Non-invasive detection of EGFR and TP53 mutations through the combination of plasma, urine and sputum in advanced non-small cell lung cancer.

Oncology Letters

Wu, Zhen Z; Yang, Zhen Z; Li, Chun-Sun CS; Zhao, Wei W; Liang, Zhi-Xin ZX; Dai, Yu Y; Zeng, Jing J; Zhu, Qiang Q; Miao, Kai-Ling KL; Cui, Dong-Hua DH; Chen, Liang-An LA

Publication Date: 2019-10

Variant appearance in text: EGFR: P848L

PubMed Link: 31516572

Variant Present in the following documents:

• Supplementary_Data.pdf

View BVdb publication page

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Characterization of epidermal growth factor receptor (EGFR) P848L, an unusual EGFR variant present in lung cancer patients, in a murine Ba/F3 model.

Febs Open Bio

Sarcar, Bhaswati B; Gimbrone, Nicholas T NT; Wright, Gabriela G; Remsing Rix, Lily L LL; Gordian, Edna R ER; Rix, Uwe U; Chiappori, Alberto A AA; Reuther, Gary W GW; Santiago-Cardona, Pedro G PG; Muñoz-Antonia, Teresita T; Cress, William Douglas WD

Publication Date: 2019-10

Variant appearance in text: EGFR: P848L

PubMed Link: 31314158

Variant Present in the following documents:

• Main text

View BVdb publication page

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The Japanese Lung Cancer Society Guideline for non-small cell lung cancer, stage IV.

International Journal Of Clinical Oncology

Akamatsu, Hiroaki H; Ninomiya, Kiichiro K; Kenmotsu, Hirotsugu H; Morise, Masahiro M; Daga, Haruko H; Goto, Yasushi Y; Kozuki, Toshiyuki T; Miura, Satoru S; Sasaki, Takaaki T; Tamiya, Akihiro A; Teraoka, Shunsuke S; Tsubata, Yukari Y; Yoshioka, Hiroshige H; Hattori, Yoshihiro Y; Imamura, Chiyo K CK; Katsuya, Yuki Y; Matsui, Reiko R; Minegishi, Yuji Y; Mizugaki, Hidenori H; Nosaki, Kaname K; Okuma, Yusuke Y; Sakamoto, Setsuko S; Sone, Takashi T; Tanaka, Kentaro K; Umemura, Shigeki S; Yamanaka, Takeharu T; Amano, Shinsuke S; Hasegawa, Kazuo K; Morita, Satoshi S; Nakajima, Kazuko K; Maemondo, Makoto M; Seto, Takashi T; Yamamoto, Nobuyuki N

Publication Date: 2019-07

Variant appearance in text: EGFR: P848L

PubMed Link: 31049758

Variant Present in the following documents:

• Main text
• 10147_2019_Article_1431.pdf

View BVdb publication page

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: EGFR: P848L

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

View BVdb publication page

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Heterogeneous Responses to Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors (TKIs) in Patients with Uncommon EGFR Mutations: New Insights and Future Perspectives in this Complex Clinical Scenario.

International Journal Of Molecular Sciences

Russo, Alessandro A; Franchina, Tindara T; Ricciardi, Giuseppina G; Battaglia, Alessandra A; Picciotto, Maria M; Adamo, Vincenzo V

Publication Date: 2019-03-21

Variant appearance in text: EGFR: P848L

PubMed Link: 30901844

Variant Present in the following documents:

• Main text
• ijms-20-01431.pdf

View BVdb publication page

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Inherited lung cancer syndromes targeting never smokers.

Translational Lung Cancer Research

Yamamoto, Hiromasa H; Yatabe, Yasushi Y; Toyooka, Shinichi S

Publication Date: 2018-08

Variant appearance in text: EGFR: P848L

PubMed Link: 30225213

Variant Present in the following documents:

• Main text

View BVdb publication page

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: EGFR: P848L

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 3
• pone.0196434.s001.xlsx, sheet 1
• pone.0196434.s001.xlsx, sheet 2

View BVdb publication page

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Clinical Analysis of Uncommon Epidermal Growth Factor Receptor Mutations in 16 Cases of Nonsmall Cell Lung Cancer.

Chinese Medical Journal

Hu, Ai-Min AM; Li, Yun-Song YS; Zhao, Dan D; Hu, Fan-Bin FB; Wang, Qun-Hui QH; Li, Bao-Lan BL

Publication Date: 2018-04-20

Variant appearance in text: EGFR: P848L

PubMed Link: 29664067

Variant Present in the following documents:

• CMJ-131-1005.pdf

View BVdb publication page

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A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched normal.

Plos Computational Biology

Sun, James X JX; He, Yuting Y; Sanford, Eric E; Montesion, Meagan M; Frampton, Garrett M GM; Vignot, Stéphane S; Soria, Jean-Charles JC; Ross, Jeffrey S JS; Miller, Vincent A VA; Stephens, Phil J PJ; Lipson, Doron D; Yelensky, Roman R

Publication Date: 2018-02

Variant appearance in text: EGFR: P848L; rs148934350

PubMed Link: 29415044

Variant Present in the following documents:

• pcbi.1005965.s007.pdf

View BVdb publication page

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Genetic variation in human drug-related genes.

Genome Medicine

Schärfe, Charlotta Pauline Irmgard CPI; Tremmel, Roman R; Schwab, Matthias M; Kohlbacher, Oliver O; Marks, Debora Susan DS

Publication Date: 2017-12-22

Variant appearance in text: rs148934350

PubMed Link: 29273096

Variant Present in the following documents:

• 13073_2017_502_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

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Oncogenic driver mutations, treatment, and EGFR-TKI resistance in a Caucasian population with non-small cell lung cancer: survival in clinical practice.

Oncotarget

Faehling, Martin M; Schwenk, Birgit B; Kramberg, Sebastian S; Eckert, Robert R; Volckmar, Anna-Lena AL; Stenzinger, Albrecht A; Sträter, Jörn J

Publication Date: 2017-09-29

Variant appearance in text: EGFR: 2543C>T; P848L

PubMed Link: 29100434

Variant Present in the following documents:

• Main text
• oncotarget-08-77897.pdf

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CA 19-9 and CA 125 as potential predictors of disease recurrence in resectable lung adenocarcinoma.

Plos One

Isaksson, Sofi S; Jönsson, Per P; Monsef, Nastaran N; Brunnström, Hans H; Bendahl, Pär-Ola PO; Jönsson, Mats M; Staaf, Johan J; Planck, Maria M

Publication Date: 2017

Variant appearance in text: EGFR: P848L

PubMed Link: 29049328

Variant Present in the following documents:

• Main text
• pone.0186284.pdf

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