Publications:

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: EGFR: G857E

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

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Assessing Genetic Variants in Matched Biocompartments From Patients With Serous Ovarian Cancer.

Technology In Cancer Research & Treatment

Sanders, Brooke E BE; Ku, Lisa L; Walker, Paul P; Bitler, Benjamin G BG

Publication Date: 2021

Variant appearance in text: EGFR: G857E

PubMed Link: 34169762

Variant Present in the following documents:

• Main text
• 10.1177_15330338211027917.pdf

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2570G>A; G857E

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Landscape of drug-resistance mutations in kinase regulatory hotspots.

Briefings In Bioinformatics

Kim, Pora P; Li, Hanyang H; Wang, Junmei J; Zhao, Zhongming Z

Publication Date: 2021-05-20

Variant appearance in text: EGFR: G857E

PubMed Link: 32510566

Variant Present in the following documents:

• Main text

View BVdb publication page

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Comprehensive Genomic Profiling of Rare Tumors: Routes to Targeted Therapies.

Frontiers In Oncology

Wang, Shuhang S; Chen, Rongrong R; Tang, Yu Y; Yu, Yue Y; Fang, Yuan Y; Huang, Huiyao H; Wu, Dawei D; Fang, Hong H; Bai, Ying Y; Sun, Chao C; Yu, Anqi A; Fan, Qi Q; Gu, Dejian D; Yi, Xin X; Li, Ning N

Publication Date: 2020

Variant appearance in text: EGFR: 2570G>A; G857E

PubMed Link: 32373528

Variant Present in the following documents:

• Table_6.xlsx, sheet 1

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: EGFR: G857E

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

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[Research Progress in Consistency of Driver Gene Status between Primary and Corresponding Metastatic Lesions in Non-small Cell Lung Cancer].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Zhou, Bing B; Xiong, Jianping J

Publication Date: 2020-03-20

Variant appearance in text: EGFR: G857E

PubMed Link: 32102137

Variant Present in the following documents:

• Main text
• zgfazz-23-3-196.pdf

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[A Review of EGFR-TKIs Therapy of Non-small Cell Lung Cancer
with Uncommon EGFR Mutations].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Du, Wenxing W; Wo, Yang Y; Lu, Tong T; Wang, Yuanyong Y; Jiao, Wenjie W

Publication Date: 2019-09-20

Variant appearance in text: EGFR: G857E

PubMed Link: 31526464

Variant Present in the following documents:

• Main text
• zgfazz-22-9-590.pdf

View BVdb publication page

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Better Progression-Free Survival in Elderly Patients with Stage IV Lung Adenocarcinoma Harboring Uncommon Epidermal Growth Factor Receptor Mutations Treated with the First-line Tyrosine Kinase Inhibitors.

Cancers

Tsai, Ming-Ju MJ; Hung, Jen-Yu JY; Lee, Mei-Hsuan MH; Kuo, Chia-Yu CY; Tsai, Yu-Chen YC; Tsai, Ying-Ming YM; Liu, Ta-Chih TC; Yang, Chih-Jen CJ; Huang, Ming-Shyan MS; Chong, Inn-Wen IW

Publication Date: 2018-11-13

Variant appearance in text: EGFR: G857E

PubMed Link: 30428509

Variant Present in the following documents:

• Main text
• cancers-10-00434.pdf

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Conformational landscape of the epidermal growth factor receptor kinase reveals a mutant specific allosteric pocket.

Chemical Science

Kannan, Srinivasaraghavan S; Venkatachalam, Gireedhar G; Lim, Hong Hwa HH; Surana, Uttam U; Verma, Chandra C

Publication Date: 2018-06-21

Variant appearance in text: EGFR: G857E

PubMed Link: 29997876

Variant Present in the following documents:

• Main text
• SC-009-C8SC01262H.pdf

View BVdb publication page

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: EGFR: G857E

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 2
• pone.0196434.s001.xlsx, sheet 3

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Clinical Analysis of Uncommon Epidermal Growth Factor Receptor Mutations in 16 Cases of Nonsmall Cell Lung Cancer.

Chinese Medical Journal

Hu, Ai-Min AM; Li, Yun-Song YS; Zhao, Dan D; Hu, Fan-Bin FB; Wang, Qun-Hui QH; Li, Bao-Lan BL

Publication Date: 2018-04-20

Variant appearance in text: EGFR: G857E

PubMed Link: 29664067

Variant Present in the following documents:

• CMJ-131-1005.pdf

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Epidermal growth factor receptor somatic mutation analysis in 354 Chinese patients with non-small cell lung cancer.

Oncology Letters

Quan, Xueping X; Gao, Hongjun H; Wang, Zhikuan Z; Li, Jie J; Zhao, Wentao W; Liang, Wei W; Yu, Qiang Q; Guo, Dongliang D; Hao, Zhanping Z; Liu, Jingxin J

Publication Date: 2018-02

Variant appearance in text: EGFR: G857E

PubMed Link: 29434916

Variant Present in the following documents:

• Main text

View BVdb publication page

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Afatinib in Non-Small Cell Lung Cancer Harboring Uncommon EGFR Mutations Pretreated With Reversible EGFR Inhibitors.

The Oncologist

Heigener, David F DF; Schumann, Christian C; Sebastian, Martin M; Sadjadian, Parvis P; Stehle, Ingo I; Märten, Angela A; Lüers, Anne A; Griesinger, Frank F; Scheffler, Matthias M; ,

Publication Date: 2015-10

Variant appearance in text: EGFR: G857E

PubMed Link: 26354527

Variant Present in the following documents:

• Main text

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HER family kinase domain mutations promote tumor progression and can predict response to treatment in human breast cancer.

Molecular Oncology

Boulbes, Delphine R DR; Arold, Stefan T ST; Chauhan, Gaurav B GB; Blachno, Korina V KV; Deng, Nanfu N; Chang, Wei-Chao WC; Jin, Quanri Q; Huang, Tzu-Hsuan TH; Hsu, Jung-Mao JM; Brady, Samuel W SW; Bartholomeusz, Chandra C; Ladbury, John E JE; Stone, Steve S; Yu, Dihua D; Hung, Mien-Chie MC; Esteva, Francisco J FJ

Publication Date: 2015-03

Variant appearance in text: EGFR: G857E

PubMed Link: 25435280

Variant Present in the following documents:

• Main text

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Screening for EGFR and KRAS mutations in non-small cell lung carcinomas using DNA extraction by hydrothermal pressure coupled with PCR-based direct sequencing.

International Journal Of Clinical And Experimental Pathology

Liu, Yan Y; Wu, Bing-Quan BQ; Zhong, Hao-Hao HH; Hui, Pei P; Fang, Wei-Gang WG

Publication Date: 2013

Variant appearance in text: EGFR: G857E

PubMed Link: 24040454

Variant Present in the following documents:

• Main text

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Assessment of computational methods for predicting the effects of missense mutations in human cancers.

Bmc Genomics

Gnad, Florian F; Baucom, Albion A; Mukhyala, Kiran K; Manning, Gerard G; Zhang, Zemin Z

Publication Date: 2013

Variant appearance in text: EGFR: G857E

PubMed Link: 23819521

Variant Present in the following documents:

• 1471-2164-14-S3-S7-S1.xlsx, sheet 2

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Aberrations in the epidermal growth factor receptor gene in 958 patients with diverse advanced tumors: implications for therapy.

Annals Of Oncology : Official Journal Of The European Society For Medical Oncology

Wheler, J J JJ; Falchook, G S GS; Tsimberidou, A M AM; Hong, D S DS; Naing, A A; Piha-Paul, S A SA; Chen, S S SS; Fu, S S; Stephen, B B; Fok, J Y JY; Janku, F F; Kurzrock, R R

Publication Date: 2013-03

Variant appearance in text: EGFR: G857E

PubMed Link: 23139256

Variant Present in the following documents:

• Main text

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Comparison of EGFR and K-RAS gene status between primary tumours and corresponding metastases in NSCLC.

British Journal Of Cancer

Kalikaki, A A; Koutsopoulos, A A; Trypaki, M M; Souglakos, J J; Stathopoulos, E E; Georgoulias, V V; Mavroudis, D D; Voutsina, A A

Publication Date: 2008-09-16

Variant appearance in text: EGFR: G857E

PubMed Link: 19238633

Variant Present in the following documents:

• Main text

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'Classical' but not 'other' mutations of EGFR kinase domain are associated with clinical outcome in gefitinib-treated patients with non-small cell lung cancer.

British Journal Of Cancer

Pallis, A G AG; Voutsina, A A; Kalikaki, Ar A; Souglakos, J J; Briasoulis, E E; Murray, S S; Koutsopoulos, A A; Tripaki, M M; Stathopoulos, E E; Mavroudis, D D; Georgoulias, V V

Publication Date: 2007-12-03

Variant appearance in text: EGFR: G857E

PubMed Link: 18000506

Variant Present in the following documents:

• Main text
• 6604068a.pdf

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