EGFR c.2570G>T ;(p.G857V)

Variant ID: 7-55259512-G-T

NM_005228.3(EGFR):c.2570G>T;(p.G857V)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Inconsistent clinical outcomes following afatinib treatment in NSCLC patients harboring uncommon epidermal growth factor receptor mutation.

Frontiers In Oncology
Dong, Wei W; Wang, Congjie C; Wang, Chunsheng C; Zhao, Kewei K; Ma, Zhao Z; Hu, Shanliang S
Publication Date: 2022

Variant appearance in text: EGFR: G857V
PubMed Link: 36425553
Variant Present in the following documents:
  • DataSheet_1.pdf
View BVdb publication page



A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.

Genome Research
Chen, Siwei S; Liu, Yuan Y; Zhang, Yingying Y; Wierbowski, Shayne D SD; Lipkin, Steven M SM; Wei, Xiaomu X; Yu, Haiyuan H
Publication Date: 2022-01

Variant appearance in text: EGFR: G857V
PubMed Link: 34963661
Variant Present in the following documents:
  • supp_gr.275437.121_Supplementary_Table_1.xlsx, sheet 3
View BVdb publication page



PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer.

Journal For Immunotherapy Of Cancer
Stein, Alexander A; Simnica, Donjete D; Schultheiß, Christoph C; Scholz, Rebekka R; Tintelnot, Joseph J; Gökkurt, Eray E; von Wenserski, Lisa L; Willscher, Edith E; Paschold, Lisa L; Sauer, Markus M; Lorenzen, Sylvie S; Riera-Knorrenschild, Jorge J; Depenbusch, Reinhard R; Ettrich, Thomas J TJ; Dörfel, Steffen S; Al-Batran, Salah-Eddin SE; Karthaus, Meinolf M; Pelzer, Uwe U; Waberer, Lisa L; Hinke, Axel A; Bauer, Marcus M; Massa, Chiara C; Seliger, Barbara B; Wickenhauser, Claudia C; Bokemeyer, Carsten C; Hegewisch-Becker, Susanna S; Binder, Mascha M
Publication Date: 2021-07

Variant appearance in text: EGFR: 2570G>T; Gly857Val
PubMed Link: 34315821
Variant Present in the following documents:
  • jitc-2021-002844supp002.xlsx, sheet 1
View BVdb publication page



The effectiveness of afatinib in patients with lung adenocarcinoma harboring complex epidermal growth factor receptor mutation.

Therapeutic Advances In Medical Oncology
Wu, Shang-Gin SG; Yu, Chong-Jen CJ; Yang, James Chih-Hsin JC; Shih, Jin-Yuan JY
Publication Date: 2020

Variant appearance in text: EGFR: G857V
PubMed Link: 32843903
Variant Present in the following documents:
  • Main text
  • 10.1177_1758835920946156.pdf
View BVdb publication page



Molecular dynamics simulation-guided drug sensitivity prediction for lung cancer with rare EGFR mutations.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Ikemura, Shinnosuke S; Yasuda, Hiroyuki H; Matsumoto, Shingo S; Kamada, Mayumi M; Hamamoto, Junko J; Masuzawa, Keita K; Kobayashi, Keigo K; Manabe, Tadashi T; Arai, Daisuke D; Nakachi, Ichiro I; Kawada, Ichiro I; Ishioka, Kota K; Nakamura, Morio M; Namkoong, Ho H; Naoki, Katsuhiko K; Ono, Fumie F; Araki, Mitsugu M; Kanada, Ryo R; Ma, Biao B; Hayashi, Yuichiro Y; Mimaki, Sachiyo S; Yoh, Kiyotaka K; Kobayashi, Susumu S SS; Kohno, Takashi T; Okuno, Yasushi Y; Goto, Koichi K; Tsuchihara, Katsuya K; Soejima, Kenzo K
Publication Date: 2019-05-14

Variant appearance in text: EGFR: G857V
PubMed Link: 31043566
Variant Present in the following documents:
  • pnas.1819430116.sapp.pdf
View BVdb publication page



Competitive evolution of NSCLC tumor clones and the drug resistance mechanism of first-generation EGFR-TKIs in Chinese NSCLC patients.

Heliyon
Deng, Qinfang Q; Xie, Boxiong B; Wu, Leilei L; Ji, Xianxiu X; Li, Chao C; Feng, Li L; Fang, Qiyu Q; Bao, Yuchen Y; Li, Jialu J; Jin, Shengnan S; Ding, Chunming C; Li, Yixue Y; Zhou, Songwen S
Publication Date: 2018-12

Variant appearance in text: EGFR: G857V
PubMed Link: 30603682
Variant Present in the following documents:
  • mmc2.xlsx, sheet 1
View BVdb publication page



Rational design of non-resistant targeted cancer therapies.

Scientific Reports
Martínez-Jiménez, Francisco F; Overington, John P JP; Al-Lazikani, Bissan B; Marti-Renom, Marc A MA
Publication Date: 2017-04-24

Variant appearance in text: EGFR: G857V
PubMed Link: 28436422
Variant Present in the following documents:
  • Main text
  • srep46632.pdf
View BVdb publication page



REGene: a literature-based knowledgebase of animal regeneration that bridge tissue regeneration and cancer.

Scientific Reports
Zhao, Min M; Rotgans, Bronwyn B; Wang, Tianfang T; Cummins, S F SF
Publication Date: 2016-03-15

Variant appearance in text: EGFR: G857V
PubMed Link: 26975833
Variant Present in the following documents:
  • srep23167-s9.xls, sheet 1
View BVdb publication page



Limited copy number-high resolution melting (LCN-HRM) enables the detection and identification by sequencing of low level mutations in cancer biopsies.

Molecular Cancer
Do, Hongdo H; Dobrovic, Alexander A
Publication Date: 2009-10-08

Variant appearance in text: EGFR: 2570G>T; G857V
PubMed Link: 19811662
Variant Present in the following documents:
  • Main text
  • 1476-4598-8-82.pdf
View BVdb publication page



High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia.

Blood
Loriaux, Marc M MM; Levine, Ross L RL; Tyner, Jeffrey W JW; Fröhling, Stefan S; Scholl, Claudia C; Stoffregen, Eric P EP; Wernig, Gerlinde G; Erickson, Heidi H; Eide, Christopher A CA; Berger, Roland R; Bernard, Olivier A OA; Griffin, James D JD; Stone, Richard M RM; Lee, Benjamin B; Meyerson, Matthew M; Heinrich, Michael C MC; Deininger, Michael W MW; Gilliland, D Gary DG; Druker, Brian J BJ
Publication Date: 2008-05-01

Variant appearance in text: EGFR: G857V
PubMed Link: 18252861
Variant Present in the following documents:
  • Main text
View BVdb publication page