Publications:

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Challenges of EGFR-TKIs in NSCLC and the potential role of herbs and active compounds: From mechanism to clinical practice.

Frontiers In Pharmacology

Song, Xiaotong X; Cao, Luchang L; Ni, Baoyi B; Wang, Jia J; Qin, Xiaoyan X; Sun, Xiaoyue X; Xu, Bowen B; Wang, Xinmiao X; Li, Jie J

Publication Date: 2023

Variant appearance in text: EGFR: l858m

PubMed Link: 37089959

Variant Present in the following documents:

• Main text
• fphar-14-1090500.pdf

View BVdb publication page

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Osimertinib in NSCLC With Atypical EGFR-Activating Mutations: A Retrospective Multicenter Study.

Jto Clinical And Research Reports

Ji, Jingran J; Aredo, Jacqueline V JV; Piper-Vallillo, Andrew A; Huppert, Laura L; Rotow, Julia K JK; Husain, Hatim H; Stewart, Susan S; Cobb, Rosemary R; Wakelee, Heather A HA; Blakely, Collin M CM; Wong, Melisa L ML; Gubens, Matthew A MA; Madani, Mohammad H MH; Digumarthy, Subba R SR; McCoach, Caroline C; Piotrowska, Zofia Z; Neal, Joel W JW; Riess, Jonathan W JW

Publication Date: 2023-03

Variant appearance in text: EGFR: L858M

PubMed Link: 36879929

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: rs121913443

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 4

View BVdb publication page

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Prognostic value of baseline genetic features and newly identified TP53 mutations in advanced breast cancer.

Molecular Oncology

Zhang, Lanxin L; Sun, Siwen S; Zhao, Xiaotian X; Liu, Jingwen J; Xu, Yang Y; Xu, Lingzhi L; Song, Chen C; Li, Na N; Yu, Jing J; Zhao, Shanshan S; Yu, Peiyao P; Fang, Fengqi F; Xie, Jiping J; Ji, Xuening X; Yu, Ruoying R; Ou, Qiuxiang Q; Zhao, Zuowei Z; Li, Man M

Publication Date: 2022-10

Variant appearance in text: EGFR: 2572C>A; L858M

PubMed Link: 35971249

Variant Present in the following documents:

• MOL2-16-3689-s005.xlsx, sheet 1

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: EGFR: 2572C>A; L858M

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology

Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J

Publication Date: 2022

Variant appearance in text: EGFR: 2572C>A; L858M

PubMed Link: 35814426

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 2

View BVdb publication page

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Afatinib 30 mg in the treatment of common and uncommon EGFR-mutated advanced lung adenocarcinomas: a retrospective, single-center, longitudinal study.

Journal Of Thoracic Disease

Qian, Jie J; Ye, Xuanting X; Huang, Aimi A; Qin, Ruoyan R; Cai, Yuqing Y; Xue, Yiqian Y; Zhang, Shi S; Wang, Weimin W; Xiong, Liwen L; Gu, Aiqin A

Publication Date: 2022-06

Variant appearance in text: EGFR: L858M

PubMed Link: 35813735

Variant Present in the following documents:

• jtd-14-06-2169.pdf

View BVdb publication page

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Genomic Alteration Spectrum of Non-Small Cell Lung Cancer Patients in East-China Characterized by Tumor Tissue DNA and Cell-Free DNA.

Oncotargets And Therapy

Li, Jie J; Chen, Siwen S; Xue, Hui H; Wang, Haoyi H; Huang, Tianwei T; Xie, Hongya H; He, Jiang J; Ke, Cai C; Yu, Zhaonan Z; Ni, Bin B

Publication Date: 2022

Variant appearance in text: EGFR: L858M

PubMed Link: 35615557

Variant Present in the following documents:

• Main text
• ott-15-571.pdf

View BVdb publication page

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: EGFR: 2572C>A; L858M

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

View BVdb publication page

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Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: L858M

PubMed Link: 35304574

Variant Present in the following documents:

• 41388_2022_Article_2263.pdf

View BVdb publication page

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Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine

Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R

Publication Date: 2022-05

Variant appearance in text: EGFR: 2572C>A; Leu858Met

PubMed Link: 35244186

Variant Present in the following documents:

• Supplementary_Data3.xlsx, sheet 1

View BVdb publication page

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Anti-angiogenesis boosts chemo-immunotherapy in patients with EGFR mutations or baseline liver metastases: insights from IMpower150 study.

Translational Cancer Research

Rebuzzi, Sara Elena SE; Facchinetti, Francesco F; Tiseo, Marcello M

Publication Date: 2019-12

Variant appearance in text: EGFR: L858M

PubMed Link: 35117143

Variant Present in the following documents:

• Main text
• tcr-08-S6-S612.pdf

View BVdb publication page

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Utility of the Ba/F3 cell system for exploring on-target mechanisms of resistance to targeted therapies for lung cancer.

Cancer Science

Koga, Takamasa T; Suda, Kenichi K; Mitsudomi, Tetsuya T

Publication Date: 2022-03

Variant appearance in text: EGFR: L858M

PubMed Link: 34997674

Variant Present in the following documents:

• CAS-113-815-s001.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: EGFR: L858M

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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The Potential Use of Dynamics Changes of ctDNA and cfDNA in the Perioperative Period to Predict the Recurrence Risk in Early NSCLC.

Frontiers In Oncology

Zhao, Xiaolong X; Dai, Fuqiang F; Mei, Longyong L; Huang, Depei D; Shen, Xudong X; Zhang, Hushan H; She, Xueke X; Ma, Zheng Z

Publication Date: 2021

Variant appearance in text: EGFR: L858M

PubMed Link: 34336662

Variant Present in the following documents:

• Main text
• fonc-11-671963.pdf

View BVdb publication page

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Successful treatment of triple EGFR mutation T785A/L861Q/H297_E298 with afatinib.

Thoracic Cancer

Longo, Vito V; Catino, Annamaria A; Montrone, Michele M; Pizzutilo, Pamela P; Pesola, Francesco F; Marech, Ilaria I; Capone, Iolanda I; Prelaj, Arsela A; Galetta, Domenico D

Publication Date: 2021-07

Variant appearance in text: EGFR: L858M

PubMed Link: 34008923

Variant Present in the following documents:

• TCA-12-2031.pdf

View BVdb publication page

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Unveiling mutational dynamics in non-small cell lung cancer patients by quantitative EGFR profiling in vesicular RNA.

Molecular Oncology

Pasini, Luigi L; Notarangelo, Michela M; Vagheggini, Alessandro A; Burgio, Marco Angelo MA; Crinò, Lucio L; Chiadini, Elisa E; Prochowski, Andrea Iamurri AI; Delmonte, Angelo A; Ulivi, Paola P; D'Agostino, Vito Giuseppe VG

Publication Date: 2021-09

Variant appearance in text: EGFR: L858M

PubMed Link: 33942501

Variant Present in the following documents:

• Main text

View BVdb publication page

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Profiling Oncogenic Germline Mutations in Unselected Chinese Lung Cancer Patients.

Frontiers In Oncology

Yang, Jie J; Li, Hefei H; Li, Ben B; Li, Wei W; Guo, Qiang Q; Hu, Ling L; Song, Zizheng Z; Zhou, Bin B

Publication Date: 2021

Variant appearance in text: EGFR: L858M

PubMed Link: 33898318

Variant Present in the following documents:

• Main text

View BVdb publication page

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Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations.

Oncotarget

Joshi, Asim A; Mishra, Rohit R; Desai, Sanket S; Chandrani, Pratik P; Kore, Hitesh H; Sunder, Roma R; Hait, Supriya S; Iyer, Prajish P; Trivedi, Vaishakhi V; Choughule, Anuradha A; Noronha, Vanita V; Joshi, Amit A; Patil, Vijay V; Menon, Nandini N; Kumar, Rajiv R; Prabhash, Kumar K; Dutt, Amit A

Publication Date: 2021-03-16

Variant appearance in text: rs121913443

PubMed Link: 33796225

Variant Present in the following documents:

• oncotarget-12-578-s005.xlsx, sheet 1

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: EGFR: 2572C>A; L858M

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Efficacy of afatinib in a patient with rare EGFR (G724S/R776H) mutations and amplification in lung adenocarcinoma: A case report.

World Journal Of Clinical Cases

He, Shu-Yan SY; Lin, Qing-Feng QF; Chen, Jie J; Yu, Gui-Ping GP; Zhang, Jun-Ling JL; Shen, Dong D

Publication Date: 2021-02-26

Variant appearance in text: EGFR: L858M

PubMed Link: 33644199

Variant Present in the following documents:

• WJCC-9-1329.pdf

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2572C>A; L858M

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Comparison of the analytical performance between the Oncomine Dx Target Test and a conventional single gene test for epidermal growth factor receptor mutation in non-small cell lung cancer.

Thoracic Cancer

Sakaguchi, Tadashi T; Iketani, Akemi A; Furuhashi, Kazuki K; Nakamura, Yuki Y; Suzuki, Yuta Y; Ito, Kentaro K; Fujiwara, Kentaro K; Nishii, Yoichi Y; Katsuta, Koji K; Taguchi, Osamu O; Hataji, Osamu O

Publication Date: 2021-02

Variant appearance in text: EGFR: L858M

PubMed Link: 33314600

Variant Present in the following documents:

• Main text

View BVdb publication page

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Detection of EGFR Mutations in Plasma Cell-Free Tumor DNA of TKI-Treated Advanced-NSCLC Patients by Three Methodologies: Scorpion-ARMS, PNAClamp, and Digital PCR.

Diagnostics (Basel, Switzerland)

Siggillino, Annamaria A; Ulivi, Paola P; Pasini, Luigi L; Reda, Maria Sole MS; Chiadini, Elisa E; Tofanetti, Francesca Romana FR; Baglivo, Sara S; Metro, Giulio G; Crinó, Lucio L; Delmonte, Angelo A; Minotti, Vincenzo V; Roila, Fausto F; Ludovini, Vienna V

Publication Date: 2020-12-07

Variant appearance in text: EGFR: L858M

PubMed Link: 33297595

Variant Present in the following documents:

• Main text
• diagnostics-10-01062.pdf

View BVdb publication page

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Unique genomic features and prognostic value of COSMIC mutational signature 4 in lung adenocarcinoma and lung squamous cell carcinoma.

Annals Of Translational Medicine

Cai, Xiuyu X; Chen, Zhenghe Z; Deng, Meiling M; Li, Zhiyong Z; Wu, Qianchao Q; Wei, Jinwang J; Dai, Chun C; Wang, Guan G; Luo, Chun C

Publication Date: 2020-09

Variant appearance in text: EGFR: L858M

PubMed Link: 33241025

Variant Present in the following documents:

• Main text
• atm-08-18-1176.pdf

View BVdb publication page

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Great Efficacy of Afatinib in a Patient with Lung Adenocarcinoma Harboring EGFR L833V/H835L Mutations: A Case Report.

Oncotargets And Therapy

Long, Xiang X; Qin, Tian T; Lin, Junhong J

Publication Date: 2020

Variant appearance in text: EGFR: L858M

PubMed Link: 33116645

Variant Present in the following documents:

• Main text
• ott-13-10689.pdf

View BVdb publication page

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Multiple mutations within individual oncogenes.

Cancer Science

Saito, Yuki Y; Koya, Junji J; Kataoka, Keisuke K

Publication Date: 2021-02

Variant appearance in text: EGFR: L858M

PubMed Link: 33073435

Variant Present in the following documents:

• Main text
• CAS-112-483.pdf

View BVdb publication page

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Usefulness of a novel device to divide core needle biopsy specimens in a spatially matched fashion.

Scientific Reports

Shiraishi, Takumi T; Inui, Shogo S; Inoue, Yuta Y; Saito, Yumiko Y; Taga, Hideto H; Kaneko, Masatomo M; Tsuji, Keisuke K; Ueda, Saya S; Ueda, Takashi T; Matsugasumi, Toru T; Taniguchi, Hidefumi H; Ueno, Akihisa A; Yamada, Takeshi T; Yamada, Yasuhiro Y; Iwata, Tsuyoshi T; Fujihara, Atsuko A; Hongo, Fumiya F; Ukimura, Osamu O

Publication Date: 2020-10-13

Variant appearance in text: rs121913443

PubMed Link: 33051506

Variant Present in the following documents:

• 41598_2020_74136_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports

Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA

Publication Date: 2020-09-21

Variant appearance in text: EGFR: L858M

PubMed Link: 32958805

Variant Present in the following documents:

• 41598_2020_72404_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

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EGFR mutation status in a series of Turkish non-small cell lung cancer patients.

Biomedical Reports

Calibasi-Kocal, Gizem G; Amirfallah, Arsalan A; Sever, Tolga T; Umit Unal, Olcun O; Gurel, Duygu D; Oztop, Ilhan I; Ellidokuz, Hulya H; Basbinar, Yasemin Y

Publication Date: 2020-08

Variant appearance in text: EGFR: Leu858Met

PubMed Link: 32509305

Variant Present in the following documents:

• Main text

View BVdb publication page

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Switching from first or second generation EGFR-TKI to osimertinib in EGFR mutation-positive NSCLC.

Lung Cancer Management

Imamura, Fumio F; Inoue, Takako T; Kunimasa, Kei K; Kubota, Aki A; Kuhara, Hanako H; Tamiya, Motohiro M; Nishino, Kazumi K; Kimura, Madoka M; Kuno, Kika K; Kawachi, Hayato H; Kumagai, Toru T

Publication Date: 2020-03-19

Variant appearance in text: EGFR: L858M

PubMed Link: 32346403

Variant Present in the following documents:

• lmt-09-29.pdf

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: EGFR: L858M

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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EGFR, KRAS, BRAF, ALK, and cMET genetic alterations in 1440 Sardinian patients with lung adenocarcinoma.

Bmc Pulmonary Medicine

Colombino, Maria M; Paliogiannis, Panagiotis P; Cossu, Antonio A; Santeufemia, Davide Adriano DA; , ; Sini, Maria Cristina MC; Casula, Milena M; Palomba, Grazia G; Manca, Antonella A; Pisano, Marina M; Doneddu, Valentina V; Palmieri, Giuseppe G

Publication Date: 2019-11-11

Variant appearance in text: EGFR: 2572C>A; L858M

PubMed Link: 31711449

Variant Present in the following documents:

View BVdb publication page

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Validation and Clinical Applications of a Comprehensive Next Generation Sequencing System for Molecular Characterization of Solid Cancer Tissues.

Frontiers In Molecular Biosciences

Dehghani, Mehdi M; Rosenblatt, Kevin P KP; Li, Lei L; Rakhade, Mrudula M; Amato, Robert J RJ

Publication Date: 2019

Variant appearance in text: EGFR: L858M

PubMed Link: 31681791

Variant Present in the following documents:

• Data_Sheet_9.xlsx, sheet 1

View BVdb publication page

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Second-generation EGFR and ErbB tyrosine kinase inhibitors as first-line treatments for non-small cell lung cancer.

Oncotargets And Therapy

Wang, Shouzheng S; Li, Junling J

Publication Date: 2019

Variant appearance in text: EGFR: L858M

PubMed Link: 31496745

Variant Present in the following documents:

• ott-12-6535.pdf

View BVdb publication page

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Treatment of uncommon EGFR mutations in non-small cell lung cancer: new evidence and treatment.

Translational Lung Cancer Research

Zhang, Tianli T; Wan, Bing B; Zhao, Yuan Y; Li, Chuling C; Liu, Hongbing H; Lv, Tangfeng T; Zhan, Ping P; Song, Yong Y

Publication Date: 2019-06

Variant appearance in text: EGFR: L858M

PubMed Link: 31367543

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmacist-led patient education and adverse event management in patients with non-small cell lung cancer receiving afatinib in a community-based, real-world clinical setting.

Journal Of Oncology Pharmacy Practice : Official Publication Of The International Society Of Oncology Pharmacy Practitioners

Khrystolubova, Natasha N; Shieh, Monica M; Patel, Anjan J AJ; Bailey, Ray R

Publication Date: 2020-01

Variant appearance in text: EGFR: L858M

PubMed Link: 30832554

Variant Present in the following documents:

• Main text
• 10.1177_1078155219833441.pdf

View BVdb publication page

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Competitive evolution of NSCLC tumor clones and the drug resistance mechanism of first-generation EGFR-TKIs in Chinese NSCLC patients.

Heliyon

Deng, Qinfang Q; Xie, Boxiong B; Wu, Leilei L; Ji, Xianxiu X; Li, Chao C; Feng, Li L; Fang, Qiyu Q; Bao, Yuchen Y; Li, Jialu J; Jin, Shengnan S; Ding, Chunming C; Li, Yixue Y; Zhou, Songwen S

Publication Date: 2018-12

Variant appearance in text: EGFR: L858M

PubMed Link: 30603682

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

View BVdb publication page

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Sensitivity of epidermal growth factor receptor with single or double uncommon mutations to afatinib confirmed by a visual assay.

Cancer Science

Kimura, Shinichi S; Tanaka, Kentaro K; Harada, Taishi T; Liu, Renpeng R; Shibahara, Daisuke D; Kawano, Yuko Y; Nakanishi, Yoichi Y; Okamoto, Isamu I

Publication Date: 2018-11

Variant appearance in text: EGFR: L858M

PubMed Link: 30255614

Variant Present in the following documents:

• Main text
• CAS-109-3657.pdf

View BVdb publication page

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Discrepancies between ALK protein disruption and occurrence of ALK gene rearrangement in Polish NSCLC patients.

Journal Of Thoracic Disease

Grenda, Anna A; Jarosz, Bożena B; Krawczyk, Paweł P; Kucharczyk, Tomasz T; Wojas-Krawczyk, Kamila K; Reszka, Katarzyna K; Krukowska, Kinga K; Nicoś, Marcin M; Pankowski, Juliusz J; Bryl, Maciej M; Ramlau, Rodryg R; Kuźnar-Kamińska, Barbara B; Grodzki, Tomasz T; Szczęsna, Aleksandra A; Siemiątkowska, Krystyna K; Szumiło, Justyna J; Batura-Gabryel, Halina H; Palonka, Michał M; Milanowski, Janusz J

Publication Date: 2018-08

Variant appearance in text: EGFR: 2572C>A; Leu858Met

PubMed Link: 30233874

Variant Present in the following documents:

• Main text

View BVdb publication page

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Fibroblast growth factor receptor 3 (FGFR3) aberrations in muscle-invasive urothelial carcinoma.

Bmc Urology

Kim, Young Saing YS; Kim, Kyung K; Kwon, Ghee-Young GY; Lee, Su Jin SJ; Park, Se Hoon SH

Publication Date: 2018-07-31

Variant appearance in text: EGFR: 2572C>A; L858M

PubMed Link: 30064409

Variant Present in the following documents:

• 12894_2018_380_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Feasibility study of cancer genome alterations identified by next generation sequencing: ABC study.

Japanese Journal Of Clinical Oncology

Naito, Yoichi Y; Takahashi, Hideaki H; Shitara, Kohei K; Okamoto, Wataru W; Bando, Hideaki H; Kuwata, Takeshi T; Kuboki, Yasutoshi Y; Matsumoto, Shingo S; Miki, Izumi I; Yamanaka, Takeharu T; Watanabe, Atsushi A; Kojima, Motohiro M

Publication Date: 2018-06-01

Variant appearance in text: EGFR: 2572C>A; L858M

PubMed Link: 29659903

Variant Present in the following documents:

• hyy052supplementaltable1ionver1.xls, sheet 1

View BVdb publication page

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Molecular Characterization of Urothelial Carcinoma of the Bladder and Upper Urinary Tract.

Translational Oncology

Lee, Ji Yun JY; Kim, Kyung K; Sung, Hyun Hwan HH; Jeon, Hwang Gyun HG; Jeong, Byong Chang BC; Seo, Seong Il SI; Jeon, Seong Soo SS; Lee, Hyun Moo HM; Choi, Han-Yong HY; Kwon, Ghee-Young GY; Kim, Kyoung-Mee KM; Lee, Jeeyun J; Lim, Ho Yeong HY; Park, Se Hoon SH

Publication Date: 2018-02

Variant appearance in text: EGFR: 2572C>A; L858M

PubMed Link: 29161613

Variant Present in the following documents:

• mmc1.xlsx, sheet 1

View BVdb publication page

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Immunohistochemical assays incorporating SP142 and 22C3 monoclonal antibodies for detection of PD-L1 expression in NSCLC patients with known status of EGFR and ALK genes.

Oncotarget

Krawczyk, Paweł P; Jarosz, Bożena B; Kucharczyk, Tomasz T; Grenda, Anna A; Reszka, Katarzyna K; Pankowski, Juliusz J; Wojas-Krawczyk, Kamila K; Nicoś, Marcin M; Szumiło, Justyna J; Trojanowski, Tomasz T; Milanowski, Janusz J

Publication Date: 2017-09-08

Variant appearance in text: EGFR: 2572C>A; Leu858Met

PubMed Link: 28969070

Variant Present in the following documents:

• Main text
• oncotarget-08-64283.pdf

View BVdb publication page

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Development and Validation of an Ultradeep Next-Generation Sequencing Assay for Testing of Plasma Cell-Free DNA from Patients with Advanced Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Janku, Filip F; Zhang, Shile S; Waters, Jill J; Liu, Li L; Huang, Helen J HJ; Subbiah, Vivek V; Hong, David S DS; Karp, Daniel D DD; Fu, Siqing S; Cai, Xuyu X; Ramzanali, Nishma M NM; Madwani, Kiran K; Cabrilo, Goran G; Andrews, Debra L DL; Zhao, Yue Y; Javle, Milind M; Kopetz, E Scott ES; Luthra, Rajyalakshmi R; Kim, Hyunsung J HJ; Gnerre, Sante S; Satya, Ravi Vijaya RV; Chuang, Han-Yu HY; Kruglyak, Kristina M KM; Toung, Jonathan J; Zhao, Chen C; Shen, Richard R; Heymach, John V JV; Meric-Bernstam, Funda F; Mills, Gordon B GB; Fan, Jian-Bing JB; Salathia, Neeraj S NS

Publication Date: 2017-09-15

Variant appearance in text: EGFR: L858M

PubMed Link: 28536309

Variant Present in the following documents:

• Main text

View BVdb publication page

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: EGFR: L858M; rs121913443

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

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Prevalence of driver mutations in non-small-cell lung cancers in the People's Republic of China.

Lung Cancer (Auckland, N.Z.)

Gou, Lan-Ying LY; Wu, Yi-Long YL

Publication Date: 2014

Variant appearance in text: EGFR: L858M

PubMed Link: 28210137

Variant Present in the following documents:

• Main text
• lctt-5-001.pdf

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Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research

Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U

Publication Date: 2017-04

Variant appearance in text: EGFR: 2572C>A; L858M

PubMed Link: 28179366

Variant Present in the following documents:

• supp_gr.213546.116_Supplemental_Table_S7.xlsx, sheet 1

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EGFR L858M/L861Q cis Mutations Confer Selective Sensitivity to Afatinib.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer

Saxon, Jamie A JA; Sholl, Lynette M LM; Jänne, Pasi A PA

Publication Date: 2017-05

Variant appearance in text: EGFR: L858M

PubMed Link: 28088511

Variant Present in the following documents:

• Main text

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Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples.

Journal Of Translational Medicine

Dallol, Ashraf A; Buhmeida, Abdelbaset A; Al-Ahwal, Mahmoud Shaheen MS; Al-Maghrabi, Jaudah J; Bajouh, Osama O; Al-Khayyat, Shadi S; Alam, Rania R; Abusanad, Atlal A; Turki, Rola R; Elaimi, Aisha A; Alhadrami, Hani A HA; Abuzenadah, Mohammed M; Banni, Huda H; Al-Qahtani, Mohammed H MH; Abuzenadah, Adel M AM

Publication Date: 2016-05-04

Variant appearance in text: EGFR: Leu858Met

PubMed Link: 27146902

Variant Present in the following documents:

• Main text
• 12967_2016_Article_878.pdf

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Determination of somatic oncogenic mutations linked to target-based therapies using MassARRAY technology.

Oncotarget

Ibarrola-Villava, Maider M; Fleitas, Tania T; Llorca-Cardeñosa, Marta J MJ; Mongort, Cristina C; Alonso, Elisa E; Navarro, Samuel S; Burgues, Octavio O; Vivancos, Ana A; Cejalvo, Juan Miguel JM; Perez-Fidalgo, José Alejandro JA; Roselló, Susana S; Ribas, Gloria G; Cervantes, Andrés A

Publication Date: 2016-04-19

Variant appearance in text: EGFR: L858M

PubMed Link: 26968814

Variant Present in the following documents:

• oncotarget-07-22543-s001.pdf

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Mutational profiling of brain metastasis from breast cancer: matched pair analysis of targeted sequencing between brain metastasis and primary breast cancer.

Oncotarget

Lee, Ji Yun JY; Park, Kyunghee K; Lim, Sung Hee SH; Kim, Hae Su HS; Yoo, Kwai Han KH; Jung, Ki Sun KS; Song, Haa-Na HN; Hong, Mineui M; Do, In-Gu IG; Ahn, TaeJin T; Lee, Se Kyung SK; Bae, Soo Youn SY; Kim, Seok Won SW; Lee, Jeong Eon JE; Nam, Seok Jin SJ; Kim, Duk-Hwan DH; Jung, Hae Hyun HH; Kim, Ji-Yeon JY; Ahn, Jin Seok JS; Im, Young-Hyuck YH; Park, Yeon Hee YH

Publication Date: 2015-12-22

Variant appearance in text: EGFR: 2572C>A; L858M

PubMed Link: 26527317

Variant Present in the following documents:

• oncotarget-06-43731-s002.xlsx, sheet 1

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Afatinib in Non-Small Cell Lung Cancer Harboring Uncommon EGFR Mutations Pretreated With Reversible EGFR Inhibitors.

The Oncologist

Heigener, David F DF; Schumann, Christian C; Sebastian, Martin M; Sadjadian, Parvis P; Stehle, Ingo I; Märten, Angela A; Lüers, Anne A; Griesinger, Frank F; Scheffler, Matthias M; ,

Publication Date: 2015-10

Variant appearance in text: EGFR: L858M

PubMed Link: 26354527

Variant Present in the following documents:

• Main text

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Patient-derived cell models as preclinical tools for genome-directed targeted therapy.

Oncotarget

Lee, Ji Yun JY; Kim, Sun Young SY; Park, Charny C; Kim, Nayoung K D NK; Jang, Jiryeon J; Park, Kyunghee K; Yi, Jun Ho JH; Hong, Mineui M; Ahn, Taejin T; Rath, Oliver O; Schueler, Julia J; Kim, Seung Tae ST; Do, In-Gu IG; Lee, Sujin S; Park, Se Hoon SH; Ji, Yong Ick YI; Kim, Dukwhan D; Park, Joon Oh JO; Park, Young Suk YS; Kang, Won Ki WK; Kim, Kyoung-Mee KM; Park, Woong-Yang WY; Lim, Ho Yeong HY; Lee, Jeeyun J

Publication Date: 2015-09-22

Variant appearance in text: EGFR: 2572C>A; L858M

PubMed Link: 26296973

Variant Present in the following documents:

• oncotarget-06-25619-s003.xls, sheet 1

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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: EGFR: L858M

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 5

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Molecular characterization of patients with pathologic complete response or early failure after neoadjuvant chemotherapy for locally advanced breast cancer using next generation sequencing and nCounter assay.

Oncotarget

Park, Kyunghee K; Choi, Moon Ki MK; Jung, Hae Hyun HH; Do, In-Gu IG; Lee, Kwang Hee KH; Ahn, TaeJin T; Kil, Won Ho WH; Kim, Seok Won SW; Lee, Jeong Eon JE; Nam, Seok Jin SJ; Kim, Duk-Hwan DH; Ahn, Jin Seok JS; Im, Young-Hyuck YH; Park, Yeon Hee YH

Publication Date: 2015-09-15

Variant appearance in text: EGFR: 2572C>A; L858M

PubMed Link: 26009992

Variant Present in the following documents:

• oncotarget-06-24499-s002.xlsx, sheet 1

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Impact of tissue type and content of neoplastic cells of samples on the quality of epidermal growth factor receptor mutation analysis among patients with lung adenocarcinoma.

Molecular Medicine Reports

Paliogiannis, Panagiotis P; Attene, Federico F; Cossu, Antonio A; Defraia, Efisio E; Porcu, Giuseppe G; Carta, Annamaria A; Sotgiu, Maria Ignazia MI; Pazzola, Antonio A; Cordero, Lorenzo L; Capelli, Francesca F; Fadda, Giovanni Maria GM; Ortu, Salvatore S; Sotgiu, Giovanni G; Palomba, Grazia G; Sini, Maria Cristina MC; Palmieri, Giuseppe G; Colombino, Maria M

Publication Date: 2015-07

Variant appearance in text: EGFR: 2572C>A; Leu858Met

PubMed Link: 25683726

Variant Present in the following documents:

• Main text
• mmr-12-01-0187.pdf

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