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EGFR c.2572C>G ;(p.L858V)
Variant ID: 7-55259514-C-G
NM_005228.3(
EGFR
):c.2572C>G;(p.L858V)
This variant was identified in 4 publications
View GRCh38 version.
Variant-Specific Resource Links:
gnomAD v2.1.1
Mutalizer Name Checker
Google
UCSC Genome Browser
ClinVar
dbSNP
Publications:
Multigene Mutation Profiling and Clinical Characteristics of Small-Cell Lung Cancer in Never-Smokers vs. Heavy Smokers (Geno1.3-CLICaP).
Frontiers In Oncology
Cardona, Andrés F AF; Rojas, Leonardo L; Zatarain-Barrón, Zyanya Lucia ZL; Ruiz-Patiño, Alejandro A; Ricaurte, Luisa L; Corrales, Luis L; Martín, Claudio C; Freitas, Helano H; Cordeiro de Lima, Vladmir Cláudio VC; Rodriguez, July J; Avila, Jenny J; Bravo, Melissa M; Archila, Pilar P; Carranza, Hernán H; Vargas, Carlos C; Otero, Jorge J; Barrón, Feliciano F; Karachaliou, Niki N; Rosell, Rafael R; Arrieta, Oscar O
Publication Date: 2019
Variant appearance in text: EGFR: L858V
PubMed Link:
31058075
Variant Present in the following documents:
Main text
fonc-09-00254.pdf
View BVdb publication page
Competitive evolution of NSCLC tumor clones and the drug resistance mechanism of first-generation EGFR-TKIs in Chinese NSCLC patients.
Heliyon
Deng, Qinfang Q; Xie, Boxiong B; Wu, Leilei L; Ji, Xianxiu X; Li, Chao C; Feng, Li L; Fang, Qiyu Q; Bao, Yuchen Y; Li, Jialu J; Jin, Shengnan S; Ding, Chunming C; Li, Yixue Y; Zhou, Songwen S
Publication Date: 2018-12
Variant appearance in text: EGFR: L858V
PubMed Link:
30603682
Variant Present in the following documents:
mmc2.xlsx, sheet 1
View BVdb publication page
Navigating into the binding pockets of the HER family protein kinases: discovery of novel EGFR inhibitor as antitumor agent.
Drug Design, Development And Therapy
Liu, Wei W; Ning, Jin-Feng JF; Meng, Qing-Wei QW; Hu, Jing J; Zhao, Yan-Bin YB; Liu, Chao C; Cai, Li L
Publication Date: 2015
Variant appearance in text: EGFR: L858V
PubMed Link:
26229444
Variant Present in the following documents:
dddt-9-3837.pdf
View BVdb publication page
Effects of oncogenic mutations on the conformational free-energy landscape of EGFR kinase.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Sutto, Ludovico L; Gervasio, Francesco Luigi FL
Publication Date: 2013-06-25
Variant appearance in text: EGFR: L858V
PubMed Link:
23754386
Variant Present in the following documents:
Main text
View BVdb publication page