Publications:

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Efficacy and Safety of Gefitinib Plus Anlotinib for Patients with EGFR Positive Advanced Non-Small-Cell Lung Cancer: A Retrospective Exploratory Study.

International Journal Of General Medicine

Hu, Wen-Xia WX; Peng, Jing-Cui JC; Wang, Yun Y; Jin, Hao H; Geng, Nan N

Publication Date: 2022

Variant appearance in text: EGFR: L858A

PubMed Link: 35509604

Variant Present in the following documents:

• Main text
• ijgm-15-4453.pdf

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Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene

Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-04

Variant appearance in text: EGFR: L858A

PubMed Link: 35304574

Variant Present in the following documents:

• 41388_2022_Article_2263.pdf

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GLP2-GLP2R signal affects the viability and EGFR-TKIs sensitivity of PC9 and HCC827 cells.

Bmc Pulmonary Medicine

Song, Bin B; Ge, Hong H; Pu, Chenwei C; Li, Ning N

Publication Date: 2022-01-13

Variant appearance in text: EGFR: L858A

PubMed Link: 35027025

Variant Present in the following documents:

• Main text
• 12890_2021_Article_1800.pdf

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GLP2-GLP2R signal affects the viability and EGFR-TKIs sensitivity of PC9 and HCC827 cells.

Bmc Pulmonary Medicine

Song, Bin B; Ge, Hong H; Pu, Chenwei C; Li, Ning N

Publication Date: 2022-01-13

Variant appearance in text: EGFR: L858A

PubMed Link: 35027025

Variant Present in the following documents:

• Main text
• 12890_2021_Article_1800.pdf

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Therapeutic advances in non-small cell lung cancer: Focus on clinical development of targeted therapy and immunotherapy.

Medcomm

Cheng, Yuan Y; Zhang, Tao T; Xu, Qing Q

Publication Date: 2021-12

Variant appearance in text: EGFR: L858A

PubMed Link: 34977873

Variant Present in the following documents:

• Main text
• MCO2-2-692.pdf

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Landscape of drug-resistance mutations in kinase regulatory hotspots.

Briefings In Bioinformatics

Kim, Pora P; Li, Hanyang H; Wang, Junmei J; Zhao, Zhongming Z

Publication Date: 2021-05-20

Variant appearance in text: EGFR: L858A

PubMed Link: 32510566

Variant Present in the following documents:

• Main text

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Targeting the miR-630/YAP1/ERK feedback loop in epidermal growth factor receptor-mutated lung adenocarcinomas.

Journal Of Thoracic Disease

Zhang, Jinglin J; Cheng, Alfred S L ASL; Yu, Jun J; To, Ka Fai KF; Kang, Wei W

Publication Date: 2018-11

Variant appearance in text: EGFR: L858A

PubMed Link: 30631543

Variant Present in the following documents:

• Main text

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Tumour-vasculature development via endothelial-to-mesenchymal transition after radiotherapy controls CD44v6+ cancer cell and macrophage polarization.

Nature Communications

Choi, Seo-Hyun SH; Kim, A-Ram AR; Nam, Jae-Kyung JK; Kim, Jin-Mo JM; Kim, Jee-Youn JY; Seo, Haeng Ran HR; Lee, Hae-June HJ; Cho, Jaeho J; Lee, Yoon-Jin YJ

Publication Date: 2018-11-30

Variant appearance in text: EGFR: L858A

PubMed Link: 30504836

Variant Present in the following documents:

• 41467_2018_7470_MOESM1_ESM.pdf

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Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine.

Nature Medicine

Van Allen, Eliezer M EM; Wagle, Nikhil N; Stojanov, Petar P; Perrin, Danielle L DL; Cibulskis, Kristian K; Marlow, Sara S; Jane-Valbuena, Judit J; Friedrich, Dennis C DC; Kryukov, Gregory G; Carter, Scott L SL; McKenna, Aaron A; Sivachenko, Andrey A; Rosenberg, Mara M; Kiezun, Adam A; Voet, Douglas D; Lawrence, Michael M; Lichtenstein, Lee T LT; Gentry, Jeff G JG; Huang, Franklin W FW; Fostel, Jennifer J; Farlow, Deborah D; Barbie, David D; Gandhi, Leena L; Lander, Eric S ES; Gray, Stacy W SW; Joffe, Steven S; Janne, Pasi P; Garber, Judy J; MacConaill, Laura L; Lindeman, Neal N; Rollins, Barrett B; Kantoff, Philip P; Fisher, Sheila A SA; Gabriel, Stacey S; Getz, Gad G; Garraway, Levi A LA

Publication Date: 2014-06

Variant appearance in text: EGFR: L858A

PubMed Link: 24836576

Variant Present in the following documents:

• NIHMS531666-supplement-10.xlsx, sheet 1

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Assessment of computational methods for predicting the effects of missense mutations in human cancers.

Bmc Genomics

Gnad, Florian F; Baucom, Albion A; Mukhyala, Kiran K; Manning, Gerard G; Zhang, Zemin Z

Publication Date: 2013

Variant appearance in text: EGFR: L858A

PubMed Link: 23819521

Variant Present in the following documents:

• 1471-2164-14-S3-S7-S1.xlsx, sheet 1

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Effects of oncogenic mutations on the conformational free-energy landscape of EGFR kinase.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Sutto, Ludovico L; Gervasio, Francesco Luigi FL

Publication Date: 2013-06-25

Variant appearance in text: EGFR: L858A

PubMed Link: 23754386

Variant Present in the following documents:

• Main text

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The energy landscape analysis of cancer mutations in protein kinases.

Plos One

Dixit, Anshuman A; Verkhivker, Gennady M GM

Publication Date: 2011

Variant appearance in text: EGFR: L858A

PubMed Link: 21998754

Variant Present in the following documents:

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Novel heteroduplex method using small cytology specimens with a remarkably high success rate for analysing EGFR gene mutations with a significant correlation to gefitinib efficacy in non-small-cell lung cancer.

British Journal Of Cancer

Oshita, F F; Matsukuma, S S; Yoshihara, M M; Sakuma, Y Y; Ohgane, N N; Kameda, Y Y; Saito, H H; Yamada, K K; Tsuchiya, E E; Miyagi, Y Y

Publication Date: 2006-10-23

Variant appearance in text: EGFR: L858A

PubMed Link: 17047654

Variant Present in the following documents:

• Main text
• 95-6603396a.pdf

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