Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway.
Nature Communications
González, Lorena L; Díaz, Lucía L; Pous, Joan J; Baginski, Blazej B; Duran-Corbera, Anna A; Scarpa, Margherita M; Brun-Heath, Isabelle I; Igea, Ana A; Martin-Malpartida, Pau P; Ruiz, Lidia L; Pallara, Chiara C; Esguerra, Mauricio M; Colizzi, Francesco F; Mayor-Ruiz, Cristina C; Biondi, Ricardo M RM; Soliva, Robert R; Macias, Maria J MJ; Orozco, Modesto M; Nebreda, Angel R AR
Non-canonical integrin signaling activates EGFR and RAS-MAPK-ERK signaling in small cell lung cancer.
Theranostics
Rubio, Karla K; Romero-Olmedo, Addi J AJ; Sarvari, Pouya P; Swaminathan, Guruprasadh G; Ranvir, Vikas P VP; Rogel-Ayala, Diana G DG; Cordero, Julio J; Günther, Stefan S; Mehta, Aditi A; Bassaly, Birgit B; Braubach, Peter P; Wygrecka, Malgorzata M; Gattenlöhner, Stefan S; Tresch, Achim A; Braun, Thomas T; Dobreva, Gergana G; Rivera, Miguel N MN; Singh, Indrabahadur I; Graumann, Johannes J; Barreto, Guillermo G
Identification of FKBP10 prognostic value in lung adenocarcinoma patients with surgical resection of brain metastases: A retrospective single-institution cohort study.
Utilisation Patterns and Treatment Outcomes of EGFR-Tyrosine Kinase Inhibitors in EGFR-mutant Advanced Lung Carcinoma in the Pakistani-Asian Population: A Real-world Data Study.
Retrospective Analysis of the Incidence of Drug-Induced Interstitial Lung Disease by Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and Survival in Patients Aged 75 Years or Older with Lung Cancer.
Jma Journal
Ishibashi, Masayuki M; Nakagawa, Yoshiko Y; Shimizu, Tetsuo T; Gon, Yasuhiro Y; Yamamoto, Hiroshi H
LncRNA LINC00969 promotes acquired gefitinib resistance by epigenetically suppressing of NLRP3 at transcriptional and posttranscriptional levels to inhibit pyroptosis in lung cancer.
Central nervous system efficacy of furmonertinib (AST2818) in patients with EGFR T790M mutated non-small cell lung cancer: a pooled analysis from two phase 2 studies.
A new class of anti-proliferative activity and apoptotic inducer with molecular docking studies for a novel of 1,3-dithiolo[4,5-b]quinoxaline derivatives hybrid with a sulfonamide moiety.
Rsc Advances
Ismail, Mostafa A MA; Abusaif, Moustafa S MS; El-Gaby, Mohamed S A MSA; Ammar, Yousry A YA; Ragab, Ahmed A
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Nature
Abbosh, Christopher C; Frankell, Alexander M AM; Harrison, Thomas T; Kisistok, Judit J; Garnett, Aaron A; Johnson, Laura L; Veeriah, Selvaraju S; Moreau, Mike M; Chesh, Adrian A; Chaunzwa, Tafadzwa L TL; Weiss, Jakob J; Schroeder, Morgan R MR; Ward, Sophia S; Grigoriadis, Kristiana K; Shahpurwalla, Aamir A; Litchfield, Kevin K; Puttick, Clare C; Biswas, Dhruva D; Karasaki, Takahiro T; Black, James R M JRM; Martínez-Ruiz, Carlos C; Bakir, Maise Al MA; Pich, Oriol O; Watkins, Thomas B K TBK; Lim, Emilia L EL; Huebner, Ariana A; Moore, David A DA; Godin-Heymann, Nadia N; L'Hernault, Anne A; Bye, Hannah H; Odell, Aaron A; Roberts, Paula P; Gomes, Fabio F; Patel, Akshay J AJ; Manzano, Elizabeth E; Hiley, Crispin T CT; Carey, Nicolas N; Riley, Joan J; Cook, Daniel E DE; Hodgson, Darren D; Stetson, Daniel D; Barrett, J Carl JC; Kortlever, Roderik M RM; Evan, Gerard I GI; Hackshaw, Allan A; Daber, Robert D RD; Shaw, Jacqui A JA; Aerts, Hugo J W L HJWL; Licon, Abel A; Stahl, Josh J; Jamal-Hanjani, Mariam M; , ; Birkbak, Nicolai J NJ; McGranahan, Nicholas N; Swanton, Charles C
The evolution of non-small cell lung cancer metastases in TRACERx.
Nature
Al Bakir, Maise M; Huebner, Ariana A; Martínez-Ruiz, Carlos C; Grigoriadis, Kristiana K; Watkins, Thomas B K TBK; Pich, Oriol O; Moore, David A DA; Veeriah, Selvaraju S; Ward, Sophia S; Laycock, Joanne J; Johnson, Diana D; Rowan, Andrew A; Razaq, Maryam M; Akther, Mita M; Naceur-Lombardelli, Cristina C; Prymas, Paulina P; Toncheva, Antonia A; Hessey, Sonya S; Dietzen, Michelle M; Colliver, Emma E; Frankell, Alexander M AM; Bunkum, Abigail A; Lim, Emilia L EL; Karasaki, Takahiro T; Abbosh, Christopher C; Hiley, Crispin T CT; Hill, Mark S MS; Cook, Daniel E DE; Wilson, Gareth A GA; Salgado, Roberto R; Nye, Emma E; Stone, Richard Kevin RK; Fennell, Dean A DA; Price, Gillian G; Kerr, Keith M KM; Naidu, Babu B; Middleton, Gary G; Summers, Yvonne Y; Lindsay, Colin R CR; Blackhall, Fiona H FH; Cave, Judith J; Blyth, Kevin G KG; Nair, Arjun A; Ahmed, Asia A; Taylor, Magali N MN; Procter, Alexander James AJ; Falzon, Mary M; Lawrence, David D; Navani, Neal N; Thakrar, Ricky M RM; Janes, Sam M SM; Papadatos-Pastos, Dionysis D; Forster, Martin D MD; Lee, Siow Ming SM; Ahmad, Tanya T; Quezada, Sergio A SA; Peggs, Karl S KS; Van Loo, Peter P; Dive, Caroline C; Hackshaw, Allan A; Birkbak, Nicolai J NJ; Zaccaria, Simone S; , ; Jamal-Hanjani, Mariam M; McGranahan, Nicholas N; Swanton, Charles C
[A Real-world Study on the Expression Characteristics of PD-L1 in Patients with Advanced EGFR Positive NSCLC and Its Relationship with the Therapeutic Efficacy of EGFR-TKIs].
Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Chen, Ran R; Gao, Xiang X; Xu, Fudong F; Zhang, Shucai S; Ma, Li L; Hu, Bo B
Discovery of an In Vivo Chemical Probe for BCL6 Inhibition by Optimization of Tricyclic Quinolinones.
Journal Of Medicinal Chemistry
Harnden, Alice C AC; Davis, Owen A OA; Box, Gary M GM; Hayes, Angela A; Johnson, Louise D LD; Henley, Alan T AT; de Haven Brandon, Alexis K AK; Valenti, Melanie M; Cheung, Kwai-Ming J KJ; Brennan, Alfie A; Huckvale, Rosemary R; Pierrat, Olivier A OA; Talbot, Rachel R; Bright, Michael D MD; Akpinar, Hafize Aysin HA; Miller, Daniel S J DSJ; Tarantino, Dalia D; Gowan, Sharon S; de Klerk, Selby S; McAndrew, Peter Craig PC; Le Bihan, Yann-Vaï YV; Meniconi, Mirco M; Burke, Rosemary R; Kirkin, Vladimir V; van Montfort, Rob L M RLM; Raynaud, Florence I FI; Rossanese, Olivia W OW; Bellenie, Benjamin R BR; Hoelder, Swen S
Osimertinib combined with bevacizumab as the first-line treatment in non-small cell lung cancer patients with brain metastasis harboring epidermal growth factor receptor mutations.
Thoracic Cancer
Zhang, Ling L; You, Yunhong Y; Liu, Xueli X; Liu, Fengjuan F; Nie, Keke K; Ji, Youxin Y
Identification of EGFR mutation status in male patients with non-small-cell lung cancer: role of 18F-FDG PET/CT and serum tumor markers CYFRA21-1 and SCC-Ag.
Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA