EGFR c.2575G>T ;(p.A859S)

Variant ID: 7-55259517-G-T

NM_005228.3(EGFR):c.2575G>T;(p.A859S)

This variant was identified in 11 publications

View GRCh38 version.




Publications:


Prognostic value of cell-free DNA in cerebrospinal fluid from lung cancer patients with brain metastases during radiotherapy.

Radiation Oncology (London, England)
Qiao, Simiao S; Hao, Yuying Y; Cai, Linbo L; Duan, Xiaotong X; Wang, Lijuan L; Zhou, Aidong A; Zhu, Xiaoxia X
Publication Date: 2023-03-11

Variant appearance in text: EGFR: A859S
PubMed Link: 36906568
Variant Present in the following documents:
  • Main text
  • 13014_2023_Article_2239.pdf
View BVdb publication page



Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology
Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J
Publication Date: 2022

Variant appearance in text: EGFR: 2575G>T; A859S
PubMed Link: 35814426
Variant Present in the following documents:
  • DataSheet_1.xlsx, sheet 2
View BVdb publication page



EGFR-dependent mechanisms of resistance to osimertinib determined by ctDNA NGS analysis identify patients with better outcome.

Translational Lung Cancer Research
Vendrell, Julie A JA; Quantin, Xavier X; Aussel, Audrey A; Solassol, Isabelle I; Serre, Isabelle I; Solassol, Jérôme J
Publication Date: 2021-11

Variant appearance in text: EGFR: A859S
PubMed Link: 35004240
Variant Present in the following documents:
  • Main text
View BVdb publication page



Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine
Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z
Publication Date: 2021-10

Variant appearance in text: EGFR: Ala859Ser
PubMed Link: 34599863
Variant Present in the following documents:
  • CAM4-10-7360-s002.xlsx, sheet 2
View BVdb publication page



Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine
Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z
Publication Date: 2021-10

Variant appearance in text: EGFR: Ala859Ser
PubMed Link: 34599863
Variant Present in the following documents:
  • CAM4-10-7360-s002.xlsx, sheet 2
View BVdb publication page



Oncogene Concatenated Enriched Amplicon Nanopore Sequencing for rapid, accurate, and affordable somatic mutation detection.

Genome Biology
Thirunavukarasu, Deepak D; Cheng, Lauren Y LY; Song, Ping P; Chen, Sherry X SX; Borad, Mitesh J MJ; Kwong, Lawrence L; James, Phillip P; Turner, Daniel J DJ; Zhang, David Yu DY
Publication Date: 2021-09-06

Variant appearance in text: EGFR: 2575G>T; A859S
PubMed Link: 34482832
Variant Present in the following documents:
  • 13059_2021_2449_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Mutation Spectrum of EGFR From 21,324 Chinese Patients With Non-Small Cell Lung Cancer (NSCLC) Successfully Tested by Multiple Methods in a CAP-Accredited Laboratory.

Pathology Oncology Research : Por
Mao, Linlin L; Zhao, Weiwei W; Li, Xiaoxia X; Zhang, Shangfei S; Zhou, Changhong C; Zhou, Danyan D; Ou, Xiaohua X; Xu, Yanyan Y; Tang, Yuanxiao Y; Ou, Xiaoyong X; Hu, Changming C; Ding, Xiangdong X; Luo, Pifu P; Yu, Shihui S
Publication Date: 2021

Variant appearance in text: EGFR: A859S
PubMed Link: 34257561
Variant Present in the following documents:
  • Main text
  • pore-27-602726.pdf
View BVdb publication page



Osimertinib Resistance With a Novel EGFR L858R/A859S/Y891D Triple Mutation in a Patient With Non-Small Cell Lung Cancer: A Case Report.

Frontiers In Oncology
Yang, Yanli Y; Zhang, Xing X; Wang, Ruixiao R; Qin, Jiayue J; Wang, Juan J; Li, Zhimin Z; Song, Xia X
Publication Date: 2020

Variant appearance in text: EGFR: A859S
PubMed Link: 33324543
Variant Present in the following documents:
  • Main text
  • fonc-10-542277.pdf
View BVdb publication page



The in cis compound EGFR mutations in Chinese advanced non-small cell lung cancer patients.

Cancer Biology & Therapy
Li, Min M; Zhou, Cheng-Zhi CZ; Yang, Jin-Ji JJ; Lu, Shun S; Zheng, Di D; Hu, Jie J; Zeng, Hui H; Lu, You Y; Lu, Kai-Hua KH; Li, Shu-Ang SA; Mao, Xin-Ru XR; Han-Zhang, Han H; Lizaso, Analyn A; Ye, Jun-Yi JY; Hu, Cheng-Ping CP
Publication Date: 2019

Variant appearance in text: EGFR: A859S
PubMed Link: 30990107
Variant Present in the following documents:
  • Main text
View BVdb publication page



Selective gene amplification to detect the T790M mutation in plasma from patients with advanced non-small cell lung cancer (NSCLC) who have developed epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) resistance.

Journal Of Thoracic Disease
Nishikawa, Shingo S; Kimura, Hideharu H; Koba, Hayato H; Yoneda, Taro T; Watanabe, Satoshi S; Sakai, Tamami T; Hara, Johsuke J; Sone, Takashi T; Kasahara, Kazuo K; Nakao, Shinji S
Publication Date: 2018-03

Variant appearance in text: EGFR: A859S
PubMed Link: 29707292
Variant Present in the following documents:
  • Main text
View BVdb publication page



Significant Improvement in Detecting BRAF, KRAS, and EGFR Mutations Using Next-Generation Sequencing as Compared with FDA-Cleared Kits.

Molecular Diagnosis & Therapy
Ma, Wanlong W; Brodie, Steven S; Agersborg, Sally S; Funari, Vincent A VA; Albitar, Maher M
Publication Date: 2017-10

Variant appearance in text: EGFR: 2575G>T; Ala859Ser
PubMed Link: 28639239
Variant Present in the following documents:
  • Main text
View BVdb publication page



Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications
Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ
Publication Date: 2017-05-11

Variant appearance in text: EGFR: A859S
PubMed Link: 28492226
Variant Present in the following documents:
  • ncomms15086.pdf
  • ncomms15086-s3.xlsx, sheet 1
  • ncomms15086-s1.pdf
View BVdb publication page