EGFR c.2578A>G ;(p.K860E)

Variant ID: 7-55259520-A-G

NM_005228.3(EGFR):c.2578A>G;(p.K860E)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Landscape of drug-resistance mutations in kinase regulatory hotspots.

Briefings In Bioinformatics
Kim, Pora P; Li, Hanyang H; Wang, Junmei J; Zhao, Zhongming Z
Publication Date: 2021-05-20

Variant appearance in text: EGFR: K860E
PubMed Link: 32510566
Variant Present in the following documents:
  • Main text
View BVdb publication page



[A Review of EGFR-TKIs Therapy of Non-small Cell Lung Cancer
with Uncommon EGFR Mutations].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer
Du, Wenxing W; Wo, Yang Y; Lu, Tong T; Wang, Yuanyong Y; Jiao, Wenjie W
Publication Date: 2019-09-20

Variant appearance in text: EGFR: K860E
PubMed Link: 31526464
Variant Present in the following documents:
  • Main text
  • zgfazz-22-9-590.pdf
View BVdb publication page



Treating EGFR-Mutated Oncogene-Addicted Advanced Non-Small-Cell Lung Cancer in the Era of Economic Crisis in Greece: Challenges and Opportunities.

Journal Of Global Oncology
Fountzilas, Elena E; Levva, Sofia S; Mountzios, Giannis G; Polychronidou, Genovefa G; Maniadakis, Nikos N; Kotoula, Vassiliki V; Fountzilas, George G
Publication Date: 2018-09

Variant appearance in text: EGFR: K860E
PubMed Link: 30260753
Variant Present in the following documents:
  • Main text
  • JGO.18.00115.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: EGFR: K860E
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 2
  • pone.0196434.s001.xlsx, sheet 1
View BVdb publication page



Efficacy of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) in targeted therapy of lung squamous cell carcinoma patients with EGFR mutation: a pooled analysis.

Oncotarget
Zhuang, Jingqi J; Yu, Yongfeng Y; Li, Ziming Z; Lu, Shun S
Publication Date: 2017-08-08

Variant appearance in text: EGFR: K860E
PubMed Link: 28881841
Variant Present in the following documents:
  • Main text
  • oncotarget-08-53675.pdf
View BVdb publication page



DNA-Mutation Inventory to Refine and Enhance Cancer Treatment (DIRECT): a catalog of clinically relevant cancer mutations to enable genome-directed anticancer therapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Yeh, Paul P; Chen, Heidi H; Andrews, Jenny J; Naser, Riyad R; Pao, William W; Horn, Leora L
Publication Date: 2013-04-01

Variant appearance in text: EGFR: K860E
PubMed Link: 23344264
Variant Present in the following documents:
  • Main text
View BVdb publication page



'Classical' but not 'other' mutations of EGFR kinase domain are associated with clinical outcome in gefitinib-treated patients with non-small cell lung cancer.

British Journal Of Cancer
Pallis, A G AG; Voutsina, A A; Kalikaki, Ar A; Souglakos, J J; Briasoulis, E E; Murray, S S; Koutsopoulos, A A; Tripaki, M M; Stathopoulos, E E; Mavroudis, D D; Georgoulias, V V
Publication Date: 2007-12-03

Variant appearance in text: EGFR: K860E
PubMed Link: 18000506
Variant Present in the following documents:
  • Main text
View BVdb publication page