EGFR c.2581_2583delinsTTT ;(p.L861F)

Variant ID: 7-55259523-CTG-TTT

NM_005228.3(EGFR):c.2581_2583delinsTTT;(p.L861F)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Preclinical assessment of combination therapy of EGFR tyrosine kinase inhibitors in a highly heterogeneous tumor model.

Oncogene
Ikeuchi, Hiroshi H; Hirose, Takeshi T; Ikegami, Masachika M; Takamochi, Kazuya K; Suzuki, Kenji K; Mano, Hiroyuki H; Kohsaka, Shinji S
Publication Date: 2022-04

Variant appearance in text: EGFR: L861F
PubMed Link: 35304574
Variant Present in the following documents:
  • Main text
  • 41388_2022_Article_2263.pdf
View BVdb publication page



The effectiveness of afatinib in patients with lung adenocarcinoma harboring complex epidermal growth factor receptor mutation.

Therapeutic Advances In Medical Oncology
Wu, Shang-Gin SG; Yu, Chong-Jen CJ; Yang, James Chih-Hsin JC; Shih, Jin-Yuan JY
Publication Date: 2020

Variant appearance in text: EGFR: L861F
PubMed Link: 32843903
Variant Present in the following documents:
  • Main text
  • 10.1177_1758835920946156.pdf
View BVdb publication page



Genomic and pathological heterogeneity in clinically diagnosed small cell lung cancer in never/light smokers identifies therapeutically targetable alterations.

Molecular Oncology
Ogino, Atsuko A; Choi, Jihyun J; Lin, Mika M; Wilkens, Margaret K MK; Calles, Antonio A; Xu, Man M; Adeni, Anika E AE; Chambers, Emily S ES; Capelletti, Marzia M; Butaney, Mohit M; Gray, Nathanael S NS; Gokhale, Prafulla C PC; Palakurthi, Sangeetha S; Kirschmeier, Paul P; Oxnard, Geoffrey R GR; Sholl, Lynette M LM; Jänne, Pasi A PA
Publication Date: 2021-01

Variant appearance in text: EGFR: L861F
PubMed Link: 32191822
Variant Present in the following documents:
  • Main text
  • MOL2-15-27.pdf
View BVdb publication page



Co-conserved features associated with cis regulation of ErbB tyrosine kinases.

Plos One
Mirza, Amar A; Mustafa, Morad M; Talevich, Eric E; Kannan, Natarajan N
Publication Date: 2010-12-13

Variant appearance in text: EGFR: L861F
PubMed Link: 21179209
Variant Present in the following documents:
  • Main text
  • pone.0014310.pdf
View BVdb publication page