EGFR c.2612C>A ;(p.A871E)

Variant ID: 7-55259554-C-A

NM_005228.3(EGFR):c.2612C>A;(p.A871E)

This variant was identified in 14 publications

View GRCh38 version.




Publications:


Pan-cancer clinical impact of latent drivers from double mutations.

Communications Biology
Yavuz, Bengi Ruken BR; Tsai, Chung-Jung CJ; Nussinov, Ruth R; Tuncbag, Nurcan N
Publication Date: 2023-02-20

Variant appearance in text: EGFR: A871E
PubMed Link: 36808143
Variant Present in the following documents:
  • 42003_2023_4519_MOESM3_ESM.xlsx, sheet 3
View BVdb publication page



Mucoepidermoid carcinoma (MEC) and adenosquamous carcinoma (ASC), the same or different entities?

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc
White, Valerie A VA; Hyrcza, Martin D MD; Lennerz, Jochen K JK; Thierauf, Julia J; Lokuhetty, Dilani D; Cree, Ian A IA; Indave, Blanca Iciar BI
Publication Date: 2022-10

Variant appearance in text: EGFR: A871E
PubMed Link: 35871081
Variant Present in the following documents:
  • 41379_2022_1100_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine
Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R
Publication Date: 2022-05

Variant appearance in text: EGFR: 2612C>A; Ala871Glu
PubMed Link: 35244186
Variant Present in the following documents:
  • Supplementary_Data3.xlsx, sheet 1
View BVdb publication page



Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine
Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z
Publication Date: 2021-10

Variant appearance in text: EGFR: Ala871Glu
PubMed Link: 34599863
Variant Present in the following documents:
  • CAM4-10-7360-s002.xlsx, sheet 2
View BVdb publication page



Driver gene alterations profiling of Chinese non-small cell lung cancer and the effects of co-occurring alterations on immunotherapy.

Cancer Medicine
Sun, Shengjie S; Du, Wenjuan W; Sun, Qiong Q; Zhao, Xiao X; Qin, Boyu B; Shi, Duozhi D; Wan, Chong C; Wu, Zhiyong Z
Publication Date: 2021-10

Variant appearance in text: EGFR: Ala871Glu
PubMed Link: 34599863
Variant Present in the following documents:
  • CAM4-10-7360-s002.xlsx, sheet 2
View BVdb publication page



A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation Subclasses.

Cancers
Koopman, Bart B; Cajiao Garcia, Betzabel N BN; Kuijpers, Chantal C H J CCHJ; Damhuis, Ronald A M RAM; van der Wekken, Anthonie J AJ; Groen, Harry J M HJM; Schuuring, Ed E; Willems, Stefan M SM; van Kempen, Léon C LC
Publication Date: 2021-07-20

Variant appearance in text: EGFR: A871E
PubMed Link: 34298851
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutation Spectrum of EGFR From 21,324 Chinese Patients With Non-Small Cell Lung Cancer (NSCLC) Successfully Tested by Multiple Methods in a CAP-Accredited Laboratory.

Pathology Oncology Research : Por
Mao, Linlin L; Zhao, Weiwei W; Li, Xiaoxia X; Zhang, Shangfei S; Zhou, Changhong C; Zhou, Danyan D; Ou, Xiaohua X; Xu, Yanyan Y; Tang, Yuanxiao Y; Ou, Xiaoyong X; Hu, Changming C; Ding, Xiangdong X; Luo, Pifu P; Yu, Shihui S
Publication Date: 2021

Variant appearance in text: EGFR: A871E
PubMed Link: 34257561
Variant Present in the following documents:
  • Main text
  • pore-27-602726.pdf
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: EGFR: 2612C>A; A871E
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Landscape of drug-resistance mutations in kinase regulatory hotspots.

Briefings In Bioinformatics
Kim, Pora P; Li, Hanyang H; Wang, Junmei J; Zhao, Zhongming Z
Publication Date: 2021-05-20

Variant appearance in text: EGFR: A871E
PubMed Link: 32510566
Variant Present in the following documents:
  • Main text
View BVdb publication page



The in cis compound EGFR mutations in Chinese advanced non-small cell lung cancer patients.

Cancer Biology & Therapy
Li, Min M; Zhou, Cheng-Zhi CZ; Yang, Jin-Ji JJ; Lu, Shun S; Zheng, Di D; Hu, Jie J; Zeng, Hui H; Lu, You Y; Lu, Kai-Hua KH; Li, Shu-Ang SA; Mao, Xin-Ru XR; Han-Zhang, Han H; Lizaso, Analyn A; Ye, Jun-Yi JY; Hu, Cheng-Ping CP
Publication Date: 2019

Variant appearance in text: EGFR: A871E
PubMed Link: 30990107
Variant Present in the following documents:
  • Main text
View BVdb publication page



Somatic mutations in leukocytes infiltrating primary breast cancers.

Npj Breast Cancer
Kleppe, Maria M; Comen, Elizabeth E; Wen, Hannah Y HY; Bastian, Lennart L; Blum, Brian B; Rapaport, Franck T FT; Keller, Matthew M; Granot, Zvika Z; Socci, Nicolas N; Viale, Agnès A; You, Daoqi D; Benezra, Robert R; Weigelt, Britta B; Brogi, Edi E; Berger, Michael F MF; Reis-Filho, Jorge S JS; Levine, Ross L RL; Norton, Larry L
Publication Date: 2015

Variant appearance in text: EGFR: A871E
PubMed Link: 28721364
Variant Present in the following documents:
  • Main text
View BVdb publication page



Non-classic EGFR mutations in a cohort of Dutch EGFR-mutated NSCLC patients and outcomes following EGFR-TKI treatment.

British Journal Of Cancer
Kuiper, J L JL; Hashemi, S M S SM; Thunnissen, E E; Snijders, P J F PJ; Grünberg, K K; Bloemena, E E; Sie, D D; Postmus, P E PE; Heideman, D A M DA; Smit, E F EF
Publication Date: 2016-12-06

Variant appearance in text: EGFR: A871E
PubMed Link: 27875527
Variant Present in the following documents:
  • Main text
  • bjc2016372a.pdf
View BVdb publication page



Irreversible EGFR-TKIs: dreaming perfection.

Translational Lung Cancer Research
Landi, Lorenza L; Cappuzzo, Federico F
Publication Date: 2013-02

Variant appearance in text: EGFR: A871E
PubMed Link: 25806203
Variant Present in the following documents:
  • Main text
View BVdb publication page



False positives in multiplex PCR-based next-generation sequencing have unique signatures.

The Journal Of Molecular Diagnostics : Jmd
McCall, Chad M CM; Mosier, Stacy S; Thiess, Michele M; Debeljak, Marija M; Pallavajjala, Aparna A; Beierl, Katie K; Deak, Kristen L KL; Datto, Michael B MB; Gocke, Christopher D CD; Lin, Ming-Tseh MT; Eshleman, James R JR
Publication Date: 2014-09

Variant appearance in text: EGFR: A871E
PubMed Link: 25017478
Variant Present in the following documents:
  • Main text
View BVdb publication page



DNA-Mutation Inventory to Refine and Enhance Cancer Treatment (DIRECT): a catalog of clinically relevant cancer mutations to enable genome-directed anticancer therapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Yeh, Paul P; Chen, Heidi H; Andrews, Jenny J; Naser, Riyad R; Pao, William W; Horn, Leora L
Publication Date: 2013-04-01

Variant appearance in text: EGFR: A871E
PubMed Link: 23344264
Variant Present in the following documents:
  • Main text
View BVdb publication page