The genomic landscape of 85 advanced neuroendocrine neoplasms reveals subtype-heterogeneity and potential therapeutic targets.
Nature Communications
van Riet, Job J; van de Werken, Harmen J G HJG; Cuppen, Edwin E; Eskens, Ferry A L M FALM; Tesselaar, Margot M; van Veenendaal, Linde M LM; Klümpen, Heinz-Josef HJ; Dercksen, Marcus W MW; Valk, Gerlof D GD; Lolkema, Martijn P MP; Sleijfer, Stefan S; Mostert, Bianca B
Publication Date: 2021-07-29
Variant appearance in text: EGFR: 2993A>T; Tyr998Phe
Pan-cancer whole-genome analyses of metastatic solid tumours.
Nature
Priestley, Peter P; Baber, Jonathan J; Lolkema, Martijn P MP; Steeghs, Neeltje N; de Bruijn, Ewart E; Shale, Charles C; Duyvesteyn, Korneel K; Haidari, Susan S; van Hoeck, Arne A; Onstenk, Wendy W; Roepman, Paul P; Voda, Mircea M; Bloemendal, Haiko J HJ; Tjan-Heijnen, Vivianne C G VCG; van Herpen, Carla M L CML; Labots, Mariette M; Witteveen, Petronella O PO; Smit, Egbert F EF; Sleijfer, Stefan S; Voest, Emile E EE; Cuppen, Edwin E
Integrated genomic approaches identify upregulation of SCRN1 as a novel mechanism associated with acquired resistance to erlotinib in PC9 cells harboring oncogenic EGFR mutation.
Oncotarget
Kim, Nayoung N; Cho, Ahye A; Watanabe, Hideo H; Choi, Yoon-La YL; Aziz, Meraj M; Kassner, Michelle M; Joung, Je-Gun JG; Park, Angela Kyung-Joo AK; Francis, Joshua M JM; Bae, Joon Seol JS; Ahn, Soo-Min SM; Kim, Kyoung-Mee KM; Park, Joon Oh JO; Park, Woong-Yang WY; Ahn, Myung-Ju MJ; Park, Keunchil K; Koo, Jaehyung J; Yin, Hongwei Holly HH; Cho, Jeonghee J
Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress.
Molecular & Cellular Proteomics : Mcp
Tong, Jiefei J; Taylor, Paul P; Moran, Michael F MF
Epidermal growth factor receptor phosphorylation sites Ser991 and Tyr998 are implicated in the regulation of receptor endocytosis and phosphorylations at Ser1039 and Thr1041.
Molecular & Cellular Proteomics : Mcp
Tong, Jiefei J; Taylor, Paul P; Peterman, Scott M SM; Prakash, Amol A; Moran, Michael F MF